ES2871035T3 - Método para la cuantificación absoluta de péptidos cancerosos restringidos a HLA que son procesados de forma natural - Google Patents

Método para la cuantificación absoluta de péptidos cancerosos restringidos a HLA que son procesados de forma natural Download PDF

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Publication number
ES2871035T3
ES2871035T3 ES15822924T ES15822924T ES2871035T3 ES 2871035 T3 ES2871035 T3 ES 2871035T3 ES 15822924 T ES15822924 T ES 15822924T ES 15822924 T ES15822924 T ES 15822924T ES 2871035 T3 ES2871035 T3 ES 2871035T3
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mhc
peptide
peptide ligand
quantification
ligand
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Spanish (es)
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Toni Weinschenk
Julia Leibold
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Immatics Biotechnologies GmbH
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539MHC-molecules, e.g. HLA-molecules
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/15Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2496/00Reference solutions for assays of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
ES15822924T 2014-12-30 2015-12-15 Método para la cuantificación absoluta de péptidos cancerosos restringidos a HLA que son procesados de forma natural Active ES2871035T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462097994P 2014-12-30 2014-12-30
GBGB1423361.3A GB201423361D0 (en) 2014-12-30 2014-12-30 Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides
PCT/EP2015/079873 WO2016107740A1 (en) 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides

Publications (1)

Publication Number Publication Date
ES2871035T3 true ES2871035T3 (es) 2021-10-28

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ES15822924T Active ES2871035T3 (es) 2014-12-30 2015-12-15 Método para la cuantificación absoluta de péptidos cancerosos restringidos a HLA que son procesados de forma natural

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Country Link
US (3) US10545154B2 (https=)
EP (1) EP3241026B1 (https=)
JP (1) JP6735741B2 (https=)
KR (1) KR102336968B1 (https=)
CN (1) CN107003322B (https=)
AU (1) AU2015373584B2 (https=)
BR (1) BR112017008212B1 (https=)
CA (1) CA2972306C (https=)
CL (1) CL2017001071A1 (https=)
CO (1) CO2017004543A2 (https=)
CR (1) CR20170297A (https=)
CY (1) CY1124223T1 (https=)
DK (1) DK3241026T3 (https=)
EA (1) EA036328B1 (https=)
ES (1) ES2871035T3 (https=)
GB (1) GB201423361D0 (https=)
HR (1) HRP20210811T1 (https=)
HU (1) HUE054455T2 (https=)
IL (1) IL250982B (https=)
LT (1) LT3241026T (https=)
MA (2) MA40137B1 (https=)
MD (1) MD3241026T2 (https=)
MX (1) MX383806B (https=)
MY (1) MY190199A (https=)
PE (1) PE20171136A1 (https=)
PH (1) PH12017500483A1 (https=)
PL (1) PL3241026T3 (https=)
PT (1) PT3241026T (https=)
RS (1) RS61914B1 (https=)
SG (2) SG10201913988XA (https=)
SI (1) SI3241026T1 (https=)
TW (1) TWI632370B (https=)
UA (1) UA122774C2 (https=)
WO (1) WO2016107740A1 (https=)
ZA (1) ZA201701646B (https=)

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BR112017008212A2 (pt) 2017-12-26
EA201791148A1 (ru) 2017-11-30
HUE054455T2 (hu) 2021-09-28
LT3241026T (lt) 2021-05-25
TW201631320A (zh) 2016-09-01
IL250982A0 (en) 2017-04-30
EP3241026B1 (en) 2021-04-14
JP6735741B2 (ja) 2020-08-05
MA41287B1 (fr) 2021-07-29
US11988669B2 (en) 2024-05-21
EA036328B1 (ru) 2020-10-27
US20160187351A1 (en) 2016-06-30
CO2017004543A2 (es) 2017-09-29
CN107003322B (zh) 2019-08-30
MA41287A (fr) 2017-11-08
HRP20210811T1 (hr) 2021-09-03
SI3241026T1 (sl) 2021-08-31
DK3241026T3 (da) 2021-05-10
MA40137A1 (fr) 2018-03-30
MX383806B (es) 2025-03-14
CA2972306A1 (en) 2016-07-07
PH12017500483A1 (en) 2017-08-07
PE20171136A1 (es) 2017-08-09
CR20170297A (es) 2017-10-19
JP2018500004A (ja) 2018-01-11
AU2015373584A1 (en) 2017-04-20
ZA201701646B (en) 2018-05-30
RS61914B1 (sr) 2021-06-30
MY190199A (en) 2022-04-04
UA122774C2 (uk) 2021-01-06
AU2015373584B2 (en) 2022-02-24
IL250982B (en) 2020-08-31
US10545154B2 (en) 2020-01-28
US20240280583A1 (en) 2024-08-22
EP3241026A1 (en) 2017-11-08
SG10201913988XA (en) 2020-03-30
PL3241026T3 (pl) 2021-10-25
MX2017008722A (es) 2017-10-18
SG11201703841VA (en) 2017-07-28
KR102336968B1 (ko) 2021-12-08
PT3241026T (pt) 2021-05-25
BR112017008212B1 (pt) 2023-11-28
CY1124223T1 (el) 2022-05-27
CL2017001071A1 (es) 2017-12-22
CA2972306C (en) 2021-02-16
WO2016107740A1 (en) 2016-07-07
KR20170099914A (ko) 2017-09-01
CN107003322A (zh) 2017-08-01
MA40137B1 (fr) 2019-05-31
TWI632370B (zh) 2018-08-11
MD3241026T2 (ro) 2021-07-31
GB201423361D0 (en) 2015-02-11
US20200103408A1 (en) 2020-04-02

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