SG11201703841VA - Method for the absolute quantification of naturally processed hla-restricted cancer peptides - Google Patents

Method for the absolute quantification of naturally processed hla-restricted cancer peptides

Info

Publication number
SG11201703841VA
SG11201703841VA SG11201703841VA SG11201703841VA SG11201703841VA SG 11201703841V A SG11201703841V A SG 11201703841VA SG 11201703841V A SG11201703841V A SG 11201703841VA SG 11201703841V A SG11201703841V A SG 11201703841VA SG 11201703841V A SG11201703841V A SG 11201703841VA
Authority
SG
Singapore
Prior art keywords
absolute quantification
naturally processed
cancer peptides
restricted cancer
processed hla
Prior art date
Application number
SG11201703841VA
Inventor
Toni Weinschenk
Julia Leibold
Original Assignee
Immatics Biotechnologies Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
Publication of SG11201703841VA publication Critical patent/SG11201703841VA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539MHC-molecules, e.g. HLA-molecules
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/15Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2496/00Reference solutions for assays of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
SG11201703841VA 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides SG11201703841VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462097994P 2014-12-30 2014-12-30
GBGB1423361.3A GB201423361D0 (en) 2014-12-30 2014-12-30 Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides
PCT/EP2015/079873 WO2016107740A1 (en) 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides

Publications (1)

Publication Number Publication Date
SG11201703841VA true SG11201703841VA (en) 2017-07-28

Family

ID=52471641

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201703841VA SG11201703841VA (en) 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides
SG10201913988XA SG10201913988XA (en) 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201913988XA SG10201913988XA (en) 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides

Country Status (35)

Country Link
US (2) US10545154B2 (en)
EP (1) EP3241026B1 (en)
JP (1) JP6735741B2 (en)
KR (1) KR102336968B1 (en)
CN (1) CN107003322B (en)
AU (1) AU2015373584B2 (en)
BR (1) BR112017008212B1 (en)
CA (1) CA2972306C (en)
CL (1) CL2017001071A1 (en)
CO (1) CO2017004543A2 (en)
CR (1) CR20170297A (en)
CY (1) CY1124223T1 (en)
DK (1) DK3241026T3 (en)
EA (1) EA036328B1 (en)
ES (1) ES2871035T3 (en)
GB (1) GB201423361D0 (en)
HR (1) HRP20210811T1 (en)
HU (1) HUE054455T2 (en)
IL (1) IL250982B (en)
LT (1) LT3241026T (en)
MA (2) MA40137B1 (en)
MD (1) MD3241026T2 (en)
MX (1) MX2017008722A (en)
MY (1) MY190199A (en)
PE (1) PE20171136A1 (en)
PH (1) PH12017500483A1 (en)
PL (1) PL3241026T3 (en)
PT (1) PT3241026T (en)
RS (1) RS61914B1 (en)
SG (2) SG11201703841VA (en)
SI (1) SI3241026T1 (en)
TW (1) TWI632370B (en)
UA (1) UA122774C2 (en)
WO (1) WO2016107740A1 (en)
ZA (1) ZA201701646B (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201423361D0 (en) * 2014-12-30 2015-02-11 Immatics Biotechnologies Gmbh Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides
CR20210232A (en) * 2015-03-17 2022-06-24 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
GB201513921D0 (en) 2015-08-05 2015-09-23 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
DE102016123893A1 (en) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T cell receptors with improved binding
EP4317432A3 (en) 2016-12-08 2024-04-17 Immatics Biotechnologies GmbH T cell receptors with improved pairing
SG11202000027WA (en) 2017-07-14 2020-02-27 Immatics Biotechnologies Gmbh Improved dual specificity polypeptide molecule
DE102017127984B4 (en) 2017-11-27 2019-12-05 Immatics US, Inc. Method for the propagation and activation of γδ T cells
CN111684062A (en) 2018-02-09 2020-09-18 伊玛提克斯美国公司 Method for producing T cell
DE102018107224A1 (en) 2018-02-21 2019-08-22 Immatics Biotechnologies Gmbh Peptides and combinations of peptides of non-canonical origin for use in immunotherapy against various cancers
KR20200027858A (en) * 2018-09-05 2020-03-13 에스케이하이닉스 주식회사 Memory controller and memory system having the same
TW202039535A (en) 2018-12-18 2020-11-01 德商英麥提克生物技術股份有限公司 Immunotherapy with b*08 restricted peptides and combination of peptides against cancers and related methods
US20200297768A1 (en) 2019-03-19 2020-09-24 Immatics US, Inc. Cd28 t cell cultures, compositions, and methods of using thereof
EA202193139A1 (en) 2019-05-27 2022-03-01 Имматикс Юс, Инк. VIRAL VECTORS AND THEIR APPLICATIONS IN ADOPTIONAL CELL THERAPY
KR20220018006A (en) 2019-06-06 2022-02-14 이매틱스 바이오테크놀로지스 게엠베하 Classification by counter selection using sequence-like peptides
US20210032370A1 (en) 2019-08-02 2021-02-04 Immatics Biotechnologies Gmbh Recruiting agent further binding an mhc molecule
DE102019121007A1 (en) 2019-08-02 2021-02-04 Immatics Biotechnologies Gmbh Antigen binding proteins that specifically bind to MAGE-A
EP4010708A1 (en) 2019-08-09 2022-06-15 Immatics US, Inc. Methods for peptide mass spectrometry fragmentation prediction
US20210048442A1 (en) 2019-08-13 2021-02-18 Immatics Biotechnologies Gmbh Method for the characterization of peptide:mhc binding polypeptides
IL295891A (en) 2020-02-24 2022-10-01 Immatics Us Inc Methods for expanding t cells for the treatment of cancer and related malignancies
DE102020111571A1 (en) 2020-03-11 2021-09-16 Immatics US, Inc. WPRE MUTANT CONSTRUCTS, COMPOSITIONS, AND RELATED PROCEDURES
DE102020106710A1 (en) 2020-03-11 2021-09-16 Immatics US, Inc. WPRE MUTANT CONSTRUCTS, COMPOSITIONS, AND RELATED PROCEDURES
AU2021275049A1 (en) 2020-05-19 2022-12-22 Amgen Inc. MAGEB2 binding constructs
WO2022040631A1 (en) 2020-08-21 2022-02-24 Immatics US, Inc. Methods for isolating cd8+ selected t cells
DE102020125457A1 (en) 2020-09-29 2022-03-31 Immatics Biotechnologies Gmbh Amidated peptides and their deamidated counterparts presented by HLA-A*02 molecules for use in immunotherapy against various types of cancer
JP2024502034A (en) 2020-12-31 2024-01-17 イマティクス ユーエス,アイエヌシー. CD8 polypeptides, compositions, and methods of using them
BR112023022975A2 (en) 2021-05-05 2024-01-23 Immatics Biotechnologies Gmbh IMPROVED BMA031 ANTIGEN BINDING POLYPEPTIDES
TW202309071A (en) 2021-05-05 2023-03-01 德商英麥提克生物技術股份有限公司 Antigen binding proteins specifically binding prame
US20230024554A1 (en) 2021-06-28 2023-01-26 Immatics Biotechnologies Gmbh Method of characterizing the binding characteristics between a peptide of interest and mhc molecules
EP4113120A1 (en) 2021-06-28 2023-01-04 Immatics Biotechnologies GmbH Method of characterizing the binding characteristics between a peptide of interest and mhc molecules
KR20240038028A (en) 2021-07-27 2024-03-22 이매틱스 바이오테크놀로지스 게엠베하 Antigen binding protein that specifically binds to CT45
WO2023025851A1 (en) 2021-08-24 2023-03-02 Immatics US, Inc. Selection of immune cells using peptide mhc complexes generated by conditional ligand exchange
TW202332765A (en) 2021-09-20 2023-08-16 美商英麥提克斯股份有限公司 Monocyte depletion of t cells populations for t-cell therapy
US20230190807A1 (en) 2021-10-06 2023-06-22 Immatics Biotechnologies Gmbh Tcr compounds, compositions, and methods of treating
WO2023081925A1 (en) 2021-11-08 2023-05-11 Immatics Biotechnologies Gmbh Adoptive cell therapy combination treatment and compositions thereof
US20240066127A1 (en) 2022-04-28 2024-02-29 Immatics US, Inc. Il-12 polypeptides, il-15 polypeptides, il-18 polypeptides, cd8 polypeptides, compositions, and methods of using thereof
US20230348561A1 (en) 2022-04-28 2023-11-02 Immatics US, Inc. Dominant negative tgfbeta receptor polypeptides, cd8 polypeptides, cells, compositions, and methods of using thereof
WO2023212697A1 (en) 2022-04-28 2023-11-02 Immatics US, Inc. Membrane-bound il-15, cd8 polypeptides, cells, compositions, and methods of using thereof
WO2023215825A1 (en) 2022-05-05 2023-11-09 Immatics US, Inc. Methods for improving t cell efficacy

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60223696T2 (en) 2001-09-14 2009-01-29 Electrophoretics Ltd., Cobham GROUND MARKER
US20050221350A1 (en) * 2002-05-29 2005-10-06 Toni Weinschenk Method for identifying immunoreactive peptides
DE10225139A1 (en) 2002-05-29 2004-02-26 Immatics Biotechnologies Gmbh Methods for the identification of immunoreactive peptides
US6644103B1 (en) 2002-10-24 2003-11-11 Simmonds Precision Products, Inc. Method and apparatus for detecting a dry/wet state of a thermistor bead
AU2003277610A1 (en) * 2002-11-08 2004-06-07 Shuichi Hanada Method of examining cancer cells and reagent therefor
US7811828B2 (en) 2004-01-28 2010-10-12 Immatics Biotechnologies Gmbh Method for identifying and quantifying of tumuor-associated
JP2008043332A (en) * 2006-08-17 2008-02-28 Panomics Inc Quantitative determination of nucleic acid from tissue slide
DK2172211T3 (en) * 2008-10-01 2015-02-16 Immatics Biotechnologies Gmbh Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers
GB201004551D0 (en) * 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer
GB201006360D0 (en) * 2010-04-16 2010-06-02 Immatics Biotechnologies Gmbh Method for differentially quantifying naturally processed HLA-restricted peptides for cancer, autoimmune and infectious diseases immunotherapy development
WO2012140429A2 (en) 2011-04-15 2012-10-18 Micromass Uk Limited Method and apparatus for the analysis of biological samples
US9869684B2 (en) 2011-06-24 2018-01-16 Definitek, Inc. Accurate measurement of glutathione for disease diagnosis and drug metabolite screening
US10077171B2 (en) * 2012-10-17 2018-09-18 Grant C. Chustz Safety barrier for vehicles and cranes
GB201423361D0 (en) * 2014-12-30 2015-02-11 Immatics Biotechnologies Gmbh Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides
DE102016115246C5 (en) * 2016-08-17 2018-12-20 Immatics Biotechnologies Gmbh NEW T-CELL RECEPTORS AND THEIR USE IN IMMUNOTHERAPY
DK3707159T3 (en) * 2017-11-06 2023-04-11 Immatics Biotechnologies Gmbh PREVIOUSLY UNKNOWN MODIFIED T CELL RECEPTORS AND IMMUNE THERAPY USING THEREOF

Also Published As

Publication number Publication date
CA2972306A1 (en) 2016-07-07
PL3241026T3 (en) 2021-10-25
CY1124223T1 (en) 2022-05-27
KR102336968B1 (en) 2021-12-08
PT3241026T (en) 2021-05-25
SG10201913988XA (en) 2020-03-30
CL2017001071A1 (en) 2017-12-22
BR112017008212A2 (en) 2017-12-26
RS61914B1 (en) 2021-06-30
MX2017008722A (en) 2017-10-18
HRP20210811T1 (en) 2021-09-03
US20200103408A1 (en) 2020-04-02
PE20171136A1 (en) 2017-08-09
GB201423361D0 (en) 2015-02-11
HUE054455T2 (en) 2021-09-28
MY190199A (en) 2022-04-04
JP6735741B2 (en) 2020-08-05
MA41287B1 (en) 2021-07-29
US20160187351A1 (en) 2016-06-30
UA122774C2 (en) 2021-01-06
IL250982A0 (en) 2017-04-30
EA036328B1 (en) 2020-10-27
TW201631320A (en) 2016-09-01
EA201791148A1 (en) 2017-11-30
CN107003322A (en) 2017-08-01
TWI632370B (en) 2018-08-11
CN107003322B (en) 2019-08-30
SI3241026T1 (en) 2021-08-31
IL250982B (en) 2020-08-31
MD3241026T2 (en) 2021-07-31
US10545154B2 (en) 2020-01-28
WO2016107740A1 (en) 2016-07-07
AU2015373584A1 (en) 2017-04-20
AU2015373584B2 (en) 2022-02-24
MA40137B1 (en) 2019-05-31
LT3241026T (en) 2021-05-25
DK3241026T3 (en) 2021-05-10
MA41287A (en) 2017-11-08
MA40137A1 (en) 2018-03-30
ES2871035T3 (en) 2021-10-28
EP3241026B1 (en) 2021-04-14
CO2017004543A2 (en) 2017-09-29
BR112017008212B1 (en) 2023-11-28
PH12017500483A1 (en) 2017-08-07
EP3241026A1 (en) 2017-11-08
CR20170297A (en) 2017-10-19
JP2018500004A (en) 2018-01-11
US11988669B2 (en) 2024-05-21
KR20170099914A (en) 2017-09-01
ZA201701646B (en) 2018-05-30
CA2972306C (en) 2021-02-16

Similar Documents

Publication Publication Date Title
ZA201701646B (en) Method for the absolute quantification of naturally processed hla-restricted cancer peptides
PT3368683T (en) Method for the quantification ofpd-l1
GB2547966B (en) De-aliased source separation method
HUP1400114A2 (en) Method for the production of peptides
GB2547965B (en) Source separation method
IL248283B (en) Method for the synthesis of clofarabine
GB201506117D0 (en) Method for chromatography
IL259107B (en) Method for decamouflaging an object
GB201614804D0 (en) Method
IL257514A (en) Cancer detection method
IL247270A0 (en) Method of detecting cancer
GB201506113D0 (en) Method for chromatography
IL258898A (en) Method for synthesizing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids
PL3336368T3 (en) Method for the stationary connection of two components
GB201616707D0 (en) Method
GB201604809D0 (en) Method for detecting cancer
GB201607828D0 (en) Method
GB201607463D0 (en) Method
GB201522150D0 (en) Saftey Apparatus
GB201600721D0 (en) Method
SG11201707200PA (en) Method for shape classification of an object
GB201518261D0 (en) Method of forming an object
AU2015903363A0 (en) Method of detecting cancer
GB201502948D0 (en) Recycling apparatus