PL3241026T3 - Metoda bezwzględnego określenia ilościowego naturalnie przetwarzanych ograniczonych do hla peptydów nowotworowych - Google Patents

Metoda bezwzględnego określenia ilościowego naturalnie przetwarzanych ograniczonych do hla peptydów nowotworowych

Info

Publication number
PL3241026T3
PL3241026T3 PL15822924T PL15822924T PL3241026T3 PL 3241026 T3 PL3241026 T3 PL 3241026T3 PL 15822924 T PL15822924 T PL 15822924T PL 15822924 T PL15822924 T PL 15822924T PL 3241026 T3 PL3241026 T3 PL 3241026T3
Authority
PL
Poland
Prior art keywords
absolute quantification
naturally processed
cancer peptides
restricted cancer
processed hla
Prior art date
Application number
PL15822924T
Other languages
English (en)
Inventor
Toni Weinschenk
Julia LEIBOLD
Original Assignee
Immatics Biotechnologies Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
Publication of PL3241026T3 publication Critical patent/PL3241026T3/pl

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539MHC-molecules, e.g. HLA-molecules
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/15Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2496/00Reference solutions for assays of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
PL15822924T 2014-12-30 2015-12-15 Metoda bezwzględnego określenia ilościowego naturalnie przetwarzanych ograniczonych do hla peptydów nowotworowych PL3241026T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462097994P 2014-12-30 2014-12-30
GBGB1423361.3A GB201423361D0 (en) 2014-12-30 2014-12-30 Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides
PCT/EP2015/079873 WO2016107740A1 (en) 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides
EP15822924.5A EP3241026B1 (en) 2014-12-30 2015-12-15 Method for the absolute quantification of naturally processed hla-restricted cancer peptides

Publications (1)

Publication Number Publication Date
PL3241026T3 true PL3241026T3 (pl) 2021-10-25

Family

ID=52471641

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15822924T PL3241026T3 (pl) 2014-12-30 2015-12-15 Metoda bezwzględnego określenia ilościowego naturalnie przetwarzanych ograniczonych do hla peptydów nowotworowych

Country Status (35)

Country Link
US (3) US10545154B2 (pl)
EP (1) EP3241026B1 (pl)
JP (1) JP6735741B2 (pl)
KR (1) KR102336968B1 (pl)
CN (1) CN107003322B (pl)
AU (1) AU2015373584B2 (pl)
BR (1) BR112017008212B1 (pl)
CA (1) CA2972306C (pl)
CL (1) CL2017001071A1 (pl)
CO (1) CO2017004543A2 (pl)
CR (1) CR20170297A (pl)
CY (1) CY1124223T1 (pl)
DK (1) DK3241026T3 (pl)
EA (1) EA036328B1 (pl)
ES (1) ES2871035T3 (pl)
GB (1) GB201423361D0 (pl)
HR (1) HRP20210811T1 (pl)
HU (1) HUE054455T2 (pl)
IL (1) IL250982B (pl)
LT (1) LT3241026T (pl)
MA (2) MA41287B1 (pl)
MD (1) MD3241026T2 (pl)
MX (1) MX2017008722A (pl)
MY (1) MY190199A (pl)
PE (1) PE20171136A1 (pl)
PH (1) PH12017500483A1 (pl)
PL (1) PL3241026T3 (pl)
PT (1) PT3241026T (pl)
RS (1) RS61914B1 (pl)
SG (2) SG11201703841VA (pl)
SI (1) SI3241026T1 (pl)
TW (1) TWI632370B (pl)
UA (1) UA122774C2 (pl)
WO (1) WO2016107740A1 (pl)
ZA (1) ZA201701646B (pl)

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CR20210232A (es) * 2015-03-17 2022-06-24 Immatics Biotechnologies Gmbh NUEVOS PÉPTIDOS Y NUEVA COMBINACIÓN DE PÉPTIDOS PARA EL USO EN LA INMUNOTERAPIA CONTRA EL CÁNCER DE PÁNCREAS Y OTROS TIPOS DE CÁNCER (Divisional 2017-0419)
GB201513921D0 (en) 2015-08-05 2015-09-23 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
NZ754222A (en) 2016-12-08 2022-02-25 Immatics Biotechnologies Gmbh T cell receptors with improved pairing
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
CR20200014A (es) 2017-07-14 2020-06-11 Immatics Biotechnologies Gmbh Molécula de polipéptido con especificidad dual mejorada
DE102017127984B4 (de) 2017-11-27 2019-12-05 Immatics US, Inc. Verfahren für die Vermehrung und Aktivierung von γδ-T-Zellen
US11464800B2 (en) * 2018-02-09 2022-10-11 Immatics US, Inc. Methods for manufacturing T cells
DE102018107224A1 (de) 2018-02-21 2019-08-22 Immatics Biotechnologies Gmbh Peptide und Kombinationen von Peptiden nicht-kanonischen Ursprungs zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten
KR20200027858A (ko) * 2018-09-05 2020-03-13 에스케이하이닉스 주식회사 메모리 컨트롤러 및 이를 포함하는 메모리 시스템
TW202039535A (zh) 2018-12-18 2020-11-01 德商英麥提克生物技術股份有限公司 B*08限制肽和肽組合物抗癌免疫治療和相關方法
US20200297768A1 (en) 2019-03-19 2020-09-24 Immatics US, Inc. Cd28 t cell cultures, compositions, and methods of using thereof
CR20210669A (es) 2019-05-27 2022-05-05 Immatics Us Inc Vectores víricos y uso de los mismos en terapias celulares adoptivas
US20200384028A1 (en) 2019-06-06 2020-12-10 Immatics Biotechnologies Gmbh Sorting with counter selection using sequence similar peptides
US20210032370A1 (en) 2019-08-02 2021-02-04 Immatics Biotechnologies Gmbh Recruiting agent further binding an mhc molecule
DE102019121007A1 (de) 2019-08-02 2021-02-04 Immatics Biotechnologies Gmbh Antigenbindende Proteine, die spezifisch an MAGE-A binden
CN114568032A (zh) 2019-08-09 2022-05-31 伊玛提克斯美国公司 肽质谱片段化预测方法
US20210048442A1 (en) 2019-08-13 2021-02-18 Immatics Biotechnologies Gmbh Method for the characterization of peptide:mhc binding polypeptides
AU2021225817A1 (en) 2020-02-24 2022-10-20 Immatics US, Inc. Methods for expanding T cells for the treatment of cancer and related malignancies
DE102020111571A1 (de) 2020-03-11 2021-09-16 Immatics US, Inc. Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
DE102020106710A1 (de) 2020-03-11 2021-09-16 Immatics US, Inc. Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
AU2021275049A1 (en) 2020-05-19 2022-12-22 Amgen Inc. MAGEB2 binding constructs
TW202227616A (zh) 2020-08-21 2022-07-16 美商英麥提克斯股份有限公司 分離cd8+選擇t細胞的方法
DE102020125457A1 (de) 2020-09-29 2022-03-31 Immatics Biotechnologies Gmbh Amidierte Peptide und ihre deamidierten Gegenstücke, die durch HLA-A*02-Moleküle präsentiert werden, zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten
TW202241938A (zh) 2020-12-31 2022-11-01 美商英麥提克斯股份有限公司 Cd8多肽、組合物及其使用方法
US20220372165A1 (en) 2021-05-05 2022-11-24 Immatics Biotechnologies Gmbh Antigen binding proteins specifically binding prame
WO2022233957A1 (en) 2021-05-05 2022-11-10 Immatics Biotechnologies Gmbh Bma031 antigen binding polypeptides
US20230024554A1 (en) 2021-06-28 2023-01-26 Immatics Biotechnologies Gmbh Method of characterizing the binding characteristics between a peptide of interest and mhc molecules
EP4113120A1 (en) 2021-06-28 2023-01-04 Immatics Biotechnologies GmbH Method of characterizing the binding characteristics between a peptide of interest and mhc molecules
EP4377330A1 (en) 2021-07-27 2024-06-05 Immatics Biotechnologies GmbH Antigen binding proteins specifically binding ct45
EP4392441A1 (en) 2021-08-24 2024-07-03 Immatics US, Inc. Selection of immune cells using peptide mhc complexes generated by conditional ligand exchange
WO2023044488A1 (en) 2021-09-20 2023-03-23 Immatics US, Inc. Monocyte depletion of t cells populations for t-cell therapy
US20230190806A1 (en) 2021-10-06 2023-06-22 Immatics Biotechnologies Gmbh Methods of treating metastatic lesions and compositions thereof
WO2023081925A1 (en) 2021-11-08 2023-05-11 Immatics Biotechnologies Gmbh Adoptive cell therapy combination treatment and compositions thereof
WO2023212691A1 (en) 2022-04-28 2023-11-02 Immatics US, Inc. DOMINANT NEGATIVE TGFβ RECEPTOR POLYPEPTIDES, CD8 POLYPEPTIDES, CELLS, COMPOSITIONS, AND METHODS OF USING THEREOF
WO2023212655A1 (en) 2022-04-28 2023-11-02 Immatics US, Inc. Il-12 polypeptides, il-15 polypeptides, il-18 polypeptides, cd8 polypeptides, compositions, and methods of using thereof
WO2023212697A1 (en) 2022-04-28 2023-11-02 Immatics US, Inc. Membrane-bound il-15, cd8 polypeptides, cells, compositions, and methods of using thereof
US20230355678A1 (en) 2022-05-05 2023-11-09 Immatics US, Inc. Methods for improving t cell efficacy

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Also Published As

Publication number Publication date
BR112017008212B1 (pt) 2023-11-28
MD3241026T2 (ro) 2021-07-31
JP2018500004A (ja) 2018-01-11
EP3241026B1 (en) 2021-04-14
RS61914B1 (sr) 2021-06-30
ZA201701646B (en) 2018-05-30
DK3241026T3 (da) 2021-05-10
CA2972306A1 (en) 2016-07-07
AU2015373584A1 (en) 2017-04-20
GB201423361D0 (en) 2015-02-11
MA41287A (fr) 2017-11-08
MA40137B1 (fr) 2019-05-31
CA2972306C (en) 2021-02-16
PH12017500483A1 (en) 2017-08-07
LT3241026T (lt) 2021-05-25
US20240280583A1 (en) 2024-08-22
US20160187351A1 (en) 2016-06-30
HUE054455T2 (hu) 2021-09-28
TW201631320A (zh) 2016-09-01
IL250982B (en) 2020-08-31
EA201791148A1 (ru) 2017-11-30
UA122774C2 (uk) 2021-01-06
WO2016107740A1 (en) 2016-07-07
EA036328B1 (ru) 2020-10-27
CL2017001071A1 (es) 2017-12-22
BR112017008212A2 (pt) 2017-12-26
CN107003322A (zh) 2017-08-01
MX2017008722A (es) 2017-10-18
CR20170297A (es) 2017-10-19
CO2017004543A2 (es) 2017-09-29
EP3241026A1 (en) 2017-11-08
CY1124223T1 (el) 2022-05-27
AU2015373584B2 (en) 2022-02-24
HRP20210811T1 (hr) 2021-09-03
CN107003322B (zh) 2019-08-30
US10545154B2 (en) 2020-01-28
MY190199A (en) 2022-04-04
MA41287B1 (fr) 2021-07-29
SG11201703841VA (en) 2017-07-28
US20200103408A1 (en) 2020-04-02
KR20170099914A (ko) 2017-09-01
TWI632370B (zh) 2018-08-11
KR102336968B1 (ko) 2021-12-08
PT3241026T (pt) 2021-05-25
IL250982A0 (en) 2017-04-30
SG10201913988XA (en) 2020-03-30
SI3241026T1 (sl) 2021-08-31
US11988669B2 (en) 2024-05-21
MA40137A1 (fr) 2018-03-30
ES2871035T3 (es) 2021-10-28
PE20171136A1 (es) 2017-08-09
JP6735741B2 (ja) 2020-08-05

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