ES2848977T5 - Métodos de tratamiento de afecciones oculares - Google Patents

Métodos de tratamiento de afecciones oculares Download PDF

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Publication number
ES2848977T5
ES2848977T5 ES15852340T ES15852340T ES2848977T5 ES 2848977 T5 ES2848977 T5 ES 2848977T5 ES 15852340 T ES15852340 T ES 15852340T ES 15852340 T ES15852340 T ES 15852340T ES 2848977 T5 ES2848977 T5 ES 2848977T5
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ES
Spain
Prior art keywords
micrograms
acetylcholine receptor
nicotinic acetylcholine
administered
receptor agonist
Prior art date
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Active
Application number
ES15852340T
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English (en)
Spanish (es)
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ES2848977T3 (es
Inventor
Douglas Michael Ackermann
James Loudin
Kenneth J Mandell
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Oyster Point Pharma Inc
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Oyster Point Pharma Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55748136&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2848977(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Oyster Point Pharma Inc filed Critical Oyster Point Pharma Inc
Application granted granted Critical
Publication of ES2848977T3 publication Critical patent/ES2848977T3/es
Publication of ES2848977T5 publication Critical patent/ES2848977T5/es
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995Pyrazines or piperazines forming part of bridged ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Emergency Medicine (AREA)
ES15852340T 2014-10-20 2015-10-19 Métodos de tratamiento de afecciones oculares Active ES2848977T5 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462066280P 2014-10-20 2014-10-20
US201562100844P 2015-01-07 2015-01-07
PCT/US2015/056273 WO2016064759A1 (en) 2014-10-20 2015-10-19 Methods of treating ocular conditions

Publications (2)

Publication Number Publication Date
ES2848977T3 ES2848977T3 (es) 2021-08-13
ES2848977T5 true ES2848977T5 (es) 2024-06-06

Family

ID=55748136

Family Applications (2)

Application Number Title Priority Date Filing Date
ES15852340T Active ES2848977T5 (es) 2014-10-20 2015-10-19 Métodos de tratamiento de afecciones oculares
ES20212556T Active ES2986830T3 (es) 2014-10-20 2015-10-19 Métodos de tratamiento de afecciones oculares

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES20212556T Active ES2986830T3 (es) 2014-10-20 2015-10-19 Métodos de tratamiento de afecciones oculares

Country Status (21)

Country Link
US (14) US9532944B2 (https=)
EP (3) EP3209295B2 (https=)
JP (3) JP6873906B2 (https=)
KR (2) KR102511955B1 (https=)
CN (3) CN111956803B (https=)
AU (2) AU2015336216B2 (https=)
BR (2) BR122022025737B1 (https=)
CA (1) CA2965129C (https=)
DK (2) DK3848028T5 (https=)
EA (1) EA035335B1 (https=)
ES (2) ES2848977T5 (https=)
FI (1) FI3848028T3 (https=)
IL (3) IL293188B2 (https=)
MX (2) MX392383B (https=)
MY (1) MY186870A (https=)
PH (1) PH12017500602A1 (https=)
PL (1) PL3848028T3 (https=)
PT (2) PT3209295T (https=)
SG (2) SG10202011669PA (https=)
WO (1) WO2016064759A1 (https=)
ZA (1) ZA201703467B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
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SG10202011669PA (en) 2014-10-20 2020-12-30 Oyster Point Pharma Inc Methods of treating ocular conditions
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TW202019417A (zh) * 2018-07-10 2020-06-01 美商奧伊斯特普安生物製藥公司 治療眼部症狀之正向異位調節劑與菸鹼乙醯膽鹼受體促效劑之組合
TW202019424A (zh) * 2018-07-10 2020-06-01 美商奧伊斯特普安生物製藥公司 治療眼部症狀之方法
ES3039903T3 (en) * 2020-04-28 2025-10-27 Oyster Point Pharma Inc Local administration of nicotinic acetylcholine receptor agonists for the inhibition of coronavirus infections
WO2025037323A1 (en) * 2023-08-12 2025-02-20 Pavan Kumar Kothapuvari Pharmaceutical compositions for treatment of dry eye disease and associated disorders
DE102023208057A1 (de) * 2023-08-23 2025-02-27 Ursapharm Arzneimittel Gmbh Ophthalmologische zusammensetzung enthaltend mindestens einen nikotinischen acetylcholinrezeptor-agonist zur topischen applikation am auge bei der prävention oder behandlung von entzündungen am auge

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TW202019417A (zh) 2018-07-10 2020-06-01 美商奧伊斯特普安生物製藥公司 治療眼部症狀之正向異位調節劑與菸鹼乙醯膽鹼受體促效劑之組合
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JP2017531044A (ja) 2017-10-19
DK3848028T5 (da) 2025-01-20
EP3209295B1 (en) 2020-12-09
US20160106745A1 (en) 2016-04-21
BR112017008097B1 (pt) 2023-03-28
KR102511955B1 (ko) 2023-03-22
MY186870A (en) 2021-08-26
US9597284B2 (en) 2017-03-21
US20200246336A1 (en) 2020-08-06
US11903943B2 (en) 2024-02-20
CA2965129C (en) 2024-03-12
JP7502404B2 (ja) 2024-06-18
US9532944B2 (en) 2017-01-03
US9504645B2 (en) 2016-11-29
JP2023024574A (ja) 2023-02-16
BR112017008097A2 (pt) 2018-02-20
EA035335B1 (ru) 2020-05-28
MX392383B (es) 2025-03-24
ES2986830T3 (es) 2024-11-12
US20250275963A1 (en) 2025-09-04
US20160106746A1 (en) 2016-04-21
US20220233528A1 (en) 2022-07-28
PT3209295T (pt) 2021-02-05
US12576080B2 (en) 2026-03-17
DK3848028T3 (da) 2024-08-26
US11911380B2 (en) 2024-02-27
US20230226053A1 (en) 2023-07-20
IL293188A (en) 2022-07-01
CN111956650B (zh) 2024-06-04
IL318427A (en) 2025-03-01
AU2015336216A1 (en) 2017-06-08
IL251769B (en) 2022-06-01
IL251769A0 (en) 2017-06-29
CN107106542B (zh) 2020-05-08
US20240173318A1 (en) 2024-05-30
US20160106665A1 (en) 2016-04-21
EP3209295B2 (en) 2023-12-06
US20170239244A1 (en) 2017-08-24
US10456396B2 (en) 2019-10-29
CN111956803A (zh) 2020-11-20
PT3848028T (pt) 2024-09-20
SG11201703135XA (en) 2017-05-30
JP7257371B2 (ja) 2023-04-13
MX2022005888A (es) 2022-06-14
US20160106744A1 (en) 2016-04-21
PL3848028T3 (pl) 2024-11-18
AU2020213351A1 (en) 2020-08-27
EA201790893A1 (ru) 2018-01-31
EP3848028B9 (en) 2024-10-16
IL293188B2 (en) 2025-06-01
US20230226052A1 (en) 2023-07-20
EP3848028A1 (en) 2021-07-14
CA2965129A1 (en) 2016-04-28
US9504644B2 (en) 2016-11-29
EP3209295A4 (en) 2018-05-23
US20250255865A1 (en) 2025-08-14
ES2848977T3 (es) 2021-08-13
CN111956650A (zh) 2020-11-20
AU2020213351B2 (en) 2023-04-06
JP6873906B2 (ja) 2021-05-19
US11903942B2 (en) 2024-02-20
KR102601505B1 (ko) 2023-11-14
AU2015336216B2 (en) 2020-05-21
CN107106542A (zh) 2017-08-29
WO2016064759A1 (en) 2016-04-28
IL293188B1 (en) 2025-02-01
CN111956803B (zh) 2025-10-31
US11224598B2 (en) 2022-01-18
PH12017500602A1 (en) 2017-09-04
FI3848028T3 (fi) 2024-08-21
DK3209295T4 (da) 2024-02-26
US11903941B2 (en) 2024-02-20
DK3209295T3 (da) 2021-03-01
EP4413974A2 (en) 2024-08-14
BR122022025737B1 (pt) 2023-12-26
KR20230042144A (ko) 2023-03-27
SG10202011669PA (en) 2020-12-30
US20230226054A1 (en) 2023-07-20
US20250235449A1 (en) 2025-07-24
EP3848028B1 (en) 2024-05-29
EP3209295A1 (en) 2017-08-30
EP4413974A3 (en) 2024-10-09
MX2017005064A (es) 2018-02-23
ZA201703467B (en) 2023-12-20
JP2021038250A (ja) 2021-03-11
KR20170086040A (ko) 2017-07-25

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