ES2847973T3 - Politerapia de anticuerpos biespecíficos anti-CD20/anti-CD3 y agonistas de 4-1BB (CD137) - Google Patents
Politerapia de anticuerpos biespecíficos anti-CD20/anti-CD3 y agonistas de 4-1BB (CD137) Download PDFInfo
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| CN108026177B (zh) | 2015-10-02 | 2021-11-26 | 豪夫迈·罗氏有限公司 | 双特异性抗cd19xcd3 t细胞活化性抗原结合分子 |
| WO2017055328A1 (en) | 2015-10-02 | 2017-04-06 | F. Hoffmann-La Roche Ag | Anti-human cd19 antibodies with high affinity |
| CR20180171A (es) | 2015-10-07 | 2018-05-03 | Hoffmann La Roche | Anticuerpos biespecíficos con tetravalencia para un receptor de fnt coestimulador |
| CA2997406C (en) * | 2015-12-09 | 2024-05-28 | F. Hoffmann-La Roche Ag | Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies or cytokine release |
| EP3231813A1 (en) | 2016-03-29 | 2017-10-18 | F. Hoffmann-La Roche AG | Trimeric costimulatory tnf family ligand-containing antigen binding molecules |
| EP3243836A1 (en) | 2016-05-11 | 2017-11-15 | F. Hoffmann-La Roche AG | C-terminally fused tnf family ligand trimer-containing antigen binding molecules |
| EP3455254B1 (en) | 2016-05-11 | 2021-07-07 | F. Hoffmann-La Roche AG | Antigen binding molecules comprising a tnf family ligand trimer and a tenascin binding moiety |
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| KR102692708B1 (ko) | 2016-12-20 | 2024-08-07 | 에프. 호프만-라 로슈 아게 | 항-cd20/항-cd3 이중특이성 항체 및 4-1bb(cd137) 작용물질의 병용 요법 |
| KR20190099527A (ko) | 2017-01-03 | 2019-08-27 | 에프. 호프만-라 로슈 아게 | 항-4-1bb 클론 20h4.9를 포함하는 이중특이성 항원 결합 분자 |
| WO2018178055A1 (en) | 2017-03-29 | 2018-10-04 | F. Hoffmann-La Roche Ag | Bispecific antigen binding molecule for a costimulatory tnf receptor |
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| AU2018247796A1 (en) | 2017-04-04 | 2019-08-29 | F. Hoffmann-La Roche Ag | Novel bispecific antigen binding molecules capable of specific binding to CD40 and to FAP |
| JP2021500902A (ja) | 2017-11-01 | 2021-01-14 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 新規ｔｎｆファミリーリガンド三量体含有抗原結合分子 |
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| EP3704155A2 (en) | 2017-11-01 | 2020-09-09 | F. Hoffmann-La Roche AG | Combination therapy with targeted ox40 agonists |
| ES2998140T3 (en) | 2018-03-13 | 2025-02-19 | Hoffmann La Roche | Therapeutic combination of 4-1bb agonists with anti-cd20 antibodies |
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| AR114284A1 (es) | 2018-04-13 | 2020-08-12 | Hoffmann La Roche | Moléculas de unión a antígeno dirigidas a her2 que comprenden 4-1bbl |
| JP2021528988A (ja) | 2018-07-04 | 2021-10-28 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 新規の二重特異性アゴニスト４−１ｂｂ抗原結合分子 |
| JP2022511396A (ja) | 2018-10-01 | 2022-01-31 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | Ｃｄ４０への三価結合を伴う二重特異性抗原結合分子 |
| UA126188C2 (uk) | 2018-10-01 | 2022-08-25 | Ф. Хоффманн-Ля Рош Аг | Біспецифічна антигензв'язувальна молекула, яка містить домен зв'язування з fap та домен зв'язування з сd40 |
| WO2020127618A1 (en) | 2018-12-21 | 2020-06-25 | F. Hoffmann-La Roche Ag | Tumor-targeted agonistic cd28 antigen binding molecules |
| EP3952996A1 (en) | 2019-04-12 | 2022-02-16 | F. Hoffmann-La Roche AG | Bispecific antigen binding molecules comprising lipocalin muteins |
| EP3990477A1 (en) | 2019-06-26 | 2022-05-04 | F. Hoffmann-La Roche AG | Fusion of an antibody binding cea and 4-1bbl |
| CA3162009A1 (en) | 2020-01-09 | 2021-07-15 | F. Hoffmann-La Roche Ag | New 4-1bbl trimer-containing antigen binding molecules |
| AR121706A1 (es) | 2020-04-01 | 2022-06-29 | Hoffmann La Roche | Moléculas de unión a antígeno biespecíficas dirigidas a ox40 y fap |
-
2017
- 2017-12-18 KR KR1020197017459A patent/KR102692708B1/ko active Active
- 2017-12-18 CA CA3039446A patent/CA3039446A1/en active Pending
- 2017-12-18 AU AU2017384126A patent/AU2017384126B2/en active Active
- 2017-12-18 EP EP17829176.1A patent/EP3559034B1/en active Active
- 2017-12-18 BR BR112019007267A patent/BR112019007267A2/pt unknown
- 2017-12-18 PL PL17829176T patent/PL3559034T3/pl unknown
- 2017-12-18 IL IL267406A patent/IL267406B2/en unknown
- 2017-12-18 ES ES17829176T patent/ES2847973T3/es active Active
- 2017-12-18 JP JP2019533085A patent/JP7247091B2/ja active Active
- 2017-12-18 MX MX2019006954A patent/MX2019006954A/es unknown
- 2017-12-18 CN CN201780078372.8A patent/CN110088135A/zh active Pending
- 2017-12-18 WO PCT/EP2017/083222 patent/WO2018114748A1/en not_active Ceased
- 2017-12-19 TW TW106144582A patent/TWI773712B/zh active
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2020
- 2020-03-16 US US16/820,504 patent/US11718680B2/en active Active
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2023
- 2023-06-13 US US18/334,228 patent/US20240109976A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2019006954A (es) | 2019-08-01 |
| TW201834684A (zh) | 2018-10-01 |
| IL267406A (en) | 2019-08-29 |
| JP2020504723A (ja) | 2020-02-13 |
| IL267406B2 (en) | 2025-05-01 |
| EP3559034A1 (en) | 2019-10-30 |
| KR20190093588A (ko) | 2019-08-09 |
| WO2018114748A1 (en) | 2018-06-28 |
| TWI773712B (zh) | 2022-08-11 |
| AU2017384126A1 (en) | 2019-05-02 |
| US11718680B2 (en) | 2023-08-08 |
| EP3559034B1 (en) | 2020-12-02 |
| CA3039446A1 (en) | 2018-06-28 |
| KR102692708B1 (ko) | 2024-08-07 |
| US20200325238A1 (en) | 2020-10-15 |
| JP7247091B2 (ja) | 2023-03-28 |
| BR112019007267A2 (pt) | 2019-07-09 |
| US20240109976A1 (en) | 2024-04-04 |
| CN110088135A (zh) | 2019-08-02 |
| PL3559034T3 (pl) | 2021-04-19 |
| AU2017384126B2 (en) | 2025-01-23 |
| IL267406B1 (en) | 2025-01-01 |
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