ES2809212T3 - Secuencia de nucleótidos que expresa una proteína de anclaje al exosoma para usar como vacuna - Google Patents

Secuencia de nucleótidos que expresa una proteína de anclaje al exosoma para usar como vacuna Download PDF

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Publication number
ES2809212T3
ES2809212T3 ES17826320T ES17826320T ES2809212T3 ES 2809212 T3 ES2809212 T3 ES 2809212T3 ES 17826320 T ES17826320 T ES 17826320T ES 17826320 T ES17826320 T ES 17826320T ES 2809212 T3 ES2809212 T3 ES 2809212T3
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nefmut
cells
exosomes
dna
antigen
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Spanish (es)
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Maurizio Paolo Maria Federico
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St Superiore Di Sanita
Istituto Superiore di Sanita ISS
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Istituto Superiore di Sanita ISS
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
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    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
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    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4267Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K40/4268MAGE
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    • A61K40/00Cellular immunotherapy
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    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
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    • C12N2710/20011Papillomaviridae
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    • C12N2740/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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ES17826320T 2016-10-11 2017-10-11 Secuencia de nucleótidos que expresa una proteína de anclaje al exosoma para usar como vacuna Active ES2809212T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102016000101794A IT201600101794A1 (it) 2016-10-11 2016-10-11 Sequenza nucleotidica esprimente una proteina ancorante esosomi per uso come vaccino.
PCT/IT2017/000223 WO2018069947A1 (en) 2016-10-11 2017-10-11 Nucleotide sequence expressing an exosome-anchoring protein for use as vaccine

Publications (1)

Publication Number Publication Date
ES2809212T3 true ES2809212T3 (es) 2021-03-03

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ES17826320T Active ES2809212T3 (es) 2016-10-11 2017-10-11 Secuencia de nucleótidos que expresa una proteína de anclaje al exosoma para usar como vacuna

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Country Link
US (2) US11559571B2 (enExample)
EP (1) EP3389701B1 (enExample)
JP (2) JP2019536473A (enExample)
KR (1) KR102620487B1 (enExample)
CN (2) CN117210480A (enExample)
AU (1) AU2017343893B2 (enExample)
BR (1) BR112019007343A2 (enExample)
CA (1) CA3040035A1 (enExample)
DK (1) DK3389701T3 (enExample)
ES (1) ES2809212T3 (enExample)
HU (1) HUE050492T2 (enExample)
IL (1) IL265942B2 (enExample)
IT (1) IT201600101794A1 (enExample)
MX (1) MX2019004183A (enExample)
RU (1) RU2761642C2 (enExample)
SG (1) SG11201903235XA (enExample)
WO (1) WO2018069947A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201600101794A1 (it) 2016-10-11 2018-04-11 St Superiore Di Sanita Sequenza nucleotidica esprimente una proteina ancorante esosomi per uso come vaccino.
IT202000009688A1 (it) 2020-05-04 2021-11-04 Biovelocita S R L Proteine di fusione di ancoraggio a esosomi
WO2021224429A1 (en) 2020-05-06 2021-11-11 Biovelocita S.R.L Exosome-anchoring coronavirus fusion proteins and vaccines
IT202000030740A1 (it) * 2020-12-14 2022-06-14 St Superiore Di Sanita SEQUENZA NUCLEOTIDICA ESPRIMENTE UNA PROTEINA ANCORANTE VESCICOLE EXTRACELLULARI FUSA AD ANTIGENI DI SARS-CoV-2 E RELATIVA PROTEINA DI FUSIONE PER L’USO COME VACCINO

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6534285B1 (en) * 1984-12-24 2003-03-18 Genentech, Inc. Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use
GB0118532D0 (en) * 2001-07-30 2001-09-19 Isis Innovation Materials and methods relating to improved vaccination strategies
FR2928926B1 (fr) 2008-03-18 2015-08-21 Centre Nat Rech Scient Polynucleotides et polypeptides chimeriques permettant la secretion d'un polypeptide d'interet en association avec des exosomes et leur utilisation pour la production de compositions immunogenes
WO2011119628A2 (en) * 2010-03-23 2011-09-29 The Regents Of The University Of California Compositions and methods for self-adjuvanting vaccines against microbes and tumors
US20130101614A1 (en) 2010-06-15 2013-04-25 The Regents Of The University Of California Novel live recombinant booster vaccine against tuberculosis
US10004793B2 (en) 2014-04-24 2018-06-26 Statens Serum Institut M.tuberculosis vaccines
IT201600101794A1 (it) 2016-10-11 2018-04-11 St Superiore Di Sanita Sequenza nucleotidica esprimente una proteina ancorante esosomi per uso come vaccino.
IT201600131935A1 (it) 2016-12-29 2018-06-29 Enea Agenzia Naz Per Le Nuove Tecnologie Lenergia E Lo Sviluppo Economico Sostenibile Sequenza segnale di proteina vegetale come coadiuvante in vaccini a DNA.
US11130787B2 (en) 2020-06-11 2021-09-28 MBF Therapeutics, Inc. Alphaherpesvirus glycoprotein d-encoding nucleic acid constructs and methods
CN112409496B (zh) 2020-11-26 2021-07-13 焦顺昌 一种跨膜表达新型冠状病毒抗原s2的融合蛋白、重组载体、重组树突状细胞及其应用

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Publication number Publication date
WO2018069947A8 (en) 2019-07-04
HUE050492T2 (hu) 2020-12-28
CA3040035A1 (en) 2018-04-19
AU2017343893B2 (en) 2024-06-13
IL265942B2 (en) 2023-11-01
JP2022071130A (ja) 2022-05-13
US20230364211A1 (en) 2023-11-16
SG11201903235XA (en) 2019-05-30
JP2019536473A (ja) 2019-12-19
KR20190079628A (ko) 2019-07-05
EP3389701B1 (en) 2020-04-29
WO2018069947A1 (en) 2018-04-19
NZ753370A (en) 2024-01-26
US11559571B2 (en) 2023-01-24
JP7340639B2 (ja) 2023-09-07
CN110049775A (zh) 2019-07-23
AU2017343893A1 (en) 2019-05-30
RU2761642C2 (ru) 2021-12-13
CN117210480A (zh) 2023-12-12
IL265942B1 (en) 2023-07-01
EP3389701A1 (en) 2018-10-24
MX2019004183A (es) 2020-09-03
IT201600101794A1 (it) 2018-04-11
IL265942A (en) 2019-05-30
RU2019114370A (ru) 2020-11-13
BR112019007343A2 (pt) 2019-10-01
US20200206329A1 (en) 2020-07-02
RU2019114370A3 (enExample) 2021-03-01
KR102620487B1 (ko) 2024-01-03
DK3389701T3 (da) 2020-08-03

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