ES2732054T3 - Matrices de monolitos con compuestos de reconocimiento unidos - Google Patents
Matrices de monolitos con compuestos de reconocimiento unidos Download PDFInfo
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- ES2732054T3 ES2732054T3 ES15743623T ES15743623T ES2732054T3 ES 2732054 T3 ES2732054 T3 ES 2732054T3 ES 15743623 T ES15743623 T ES 15743623T ES 15743623 T ES15743623 T ES 15743623T ES 2732054 T3 ES2732054 T3 ES 2732054T3
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- monolith
- nucleic acid
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- chemical
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
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- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
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- Treatment Of Liquids With Adsorbents In General (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
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| PCT/US2015/013382 WO2015116739A1 (en) | 2014-01-28 | 2015-01-28 | Monoliths with attached recognition compounds, arrays thereof and uses thereof |
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| JP6564369B2 (ja) | 2013-12-09 | 2019-08-21 | デュレクト コーポレイション | 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法 |
| WO2017119503A1 (ja) * | 2016-01-08 | 2017-07-13 | 株式会社ジーンデザイン | ゾル－ゲル法で作製される無機多孔質体を用いた核酸合成用担体 |
| EP3464590A4 (en) * | 2016-06-05 | 2020-04-01 | Dice Molecules SV, LLC | ROUTING METHODS, COMPOSITIONS AND USES THEREOF |
| EP3837344A4 (en) * | 2018-08-17 | 2022-01-26 | Sierra Biosystems, Inc. | ROW-INDEPENDENT OLIGONUCLEOTIDE SYNTHESIS |
| CN110724623A (zh) * | 2019-09-10 | 2020-01-24 | 深圳市百迈生命科学有限公司 | 1536孔固相合成与萃取板 |
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| GB1123878A (en) | 1966-08-23 | 1968-08-14 | Ici Ltd | Synthesis of norbornene derivatives |
| US4889632A (en) | 1987-12-10 | 1989-12-26 | Ceskoslovenska Akademie Ved | Macroporous polymeric membranes for the separation of polymers and a method of their application |
| EP0554407A1 (en) | 1990-10-26 | 1993-08-11 | Genta Incorporated | Non-aromatic organic polymeric reagents for solid phase synthesis of oligomers |
| DK51092D0 (da) | 1991-05-24 | 1992-04-15 | Ole Buchardt | Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf |
| US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
| US5281368A (en) | 1992-03-31 | 1994-01-25 | Exxon Chemical Patents Inc. | Norbornene polymerization initiators and process for preparing same |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| WO1999005320A1 (en) * | 1997-07-22 | 1999-02-04 | Rapigene, Inc. | Multiple functionalities within an array element and uses thereof |
| AU4437399A (en) | 1998-06-12 | 1999-12-30 | Waters Investments Limited | Novel ion exchange porous resins for solid phase extraction and chromatography |
| US6238565B1 (en) | 1998-09-16 | 2001-05-29 | Varian, Inc. | Monolithic matrix for separating bio-organic molecules |
| WO2000023458A1 (en) | 1998-10-19 | 2000-04-27 | The Board Of Trustees Of The Leland Stanford Junior University | Dna-templated combinatorial library chemistry |
| US6919181B2 (en) | 2002-03-25 | 2005-07-19 | Agilent Technologies, Inc. | Methods for generating ligand arrays |
| US7473367B2 (en) | 2002-06-26 | 2009-01-06 | Dionex Corporation | Monolithic column |
| US20040200776A1 (en) * | 2003-01-17 | 2004-10-14 | Ivanov Alexander R. | Narrow I.D. monolithic capillary columns for high efficiency separation and high sensitivity analysis of biomolecules |
| US20050095602A1 (en) | 2003-11-04 | 2005-05-05 | West Jason A. | Microfluidic integrated microarrays for biological detection |
| WO2005078088A1 (ja) | 2004-02-12 | 2005-08-25 | Gl Sciences Incorporated | Ｄｎａなどの分離精製機構 |
| US7897378B2 (en) | 2004-03-18 | 2011-03-01 | Roche Molecular Systems, Inc. | Method and device for purifying nucleic acids |
| JP2006015333A (ja) * | 2004-05-31 | 2006-01-19 | Showa Denko Kk | 有機ポリマーモノリス、その製造方法、およびその用途 |
| EP1786552A1 (en) * | 2004-08-27 | 2007-05-23 | Applera Corporation | Method of making polymer monolith composite substrate and resulting substrate as well as beads and bead array |
| WO2006047791A2 (en) * | 2004-10-27 | 2006-05-04 | The Board Of Trustees Of The Leland Stanford Junior University | Dna-templated combinatorial library device and method for use |
| US8394492B1 (en) | 2004-10-28 | 2013-03-12 | The United States Of America As Represented By The United States National Aeronautics And Space Administration | Surface modified aerogel monoliths |
| CN101400993A (zh) | 2005-11-10 | 2009-04-01 | 阿普尔拉股份有限公司 | 包括多孔聚合物电极的微流体系统 |
| DE102005059315A1 (de) | 2005-12-09 | 2007-06-14 | Qiagen Gmbh | Verfahren zur Anreicherung von kurzkettigen Nukleinsäuren |
| US7608399B2 (en) | 2006-06-26 | 2009-10-27 | Blood Cell Storage, Inc. | Device and method for extraction and analysis of nucleic acids from biological samples |
| GB0614727D0 (en) * | 2006-07-25 | 2006-09-06 | Chromatide Ltd | Solid support |
| CA2629589C (en) | 2007-04-20 | 2016-03-29 | F.Hoffmann-La Roche Ag | Isolation and purification of nucleic acid molecules with a solid phase |
| JP2010507831A (ja) | 2007-04-23 | 2010-03-11 | エルジー・ケム・リミテッド | 位相差フィルム、その製造方法及び位相差フィルムを含む偏光板 |
| CN101861518B (zh) | 2007-10-17 | 2012-05-30 | 株式会社岛津制作所 | 色谱分析用整体柱分离介质及其制造方法 |
| EP2174916B9 (fr) | 2008-10-09 | 2017-11-22 | Université Des Sciences Et Technologies De Lille | Monolithes de silice de haute pureté et son procédé de synthèse |
| WO2010053443A1 (en) | 2008-11-06 | 2010-05-14 | Agency For Science, Technology And Research | Apparatus for biopolymer synthesis |
| EP2335820A1 (en) | 2009-12-18 | 2011-06-22 | Leopold-Franzens-Universität Innsbruck | Method for covalently attaching polymeric monoliths to polyether ether ketone (PEEK) surfaces |
| BR112012016882B1 (pt) | 2010-01-08 | 2021-02-23 | University Of Tasmania | método de armazenamento de um fluido corpóreo para análise futura |
| US20110240541A1 (en) | 2010-04-06 | 2011-10-06 | Binghe Gu | Monolithic column technology for liquid chromatography |
| MX354845B (es) * | 2010-05-18 | 2018-03-22 | Abbvie Inc Star | Aparato y proceso de purificación de proteínas. |
| US8603833B2 (en) | 2010-06-03 | 2013-12-10 | University Of South Florida | Germania-silica-based sol-gel monolith and uses thereof |
| JP5826256B2 (ja) | 2010-06-08 | 2015-12-02 | フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ | 付香成分としてのビシクロケトン |
| EP2405000A1 (en) | 2010-07-06 | 2012-01-11 | Alacris Theranostics GmbH | Synthesis of chemical libraries |
| US20150315569A1 (en) | 2014-05-02 | 2015-11-05 | The Board Of Trustees Of The Leland Stanford Junior University | Method for screening a nucleic acid-programmed small molecule library |
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| CN106459978B (zh) | 2020-05-19 |
| AU2015211020A1 (en) | 2016-08-11 |
| BR112016017152A2 (pt) | 2017-08-08 |
| WO2015116739A1 (en) | 2015-08-06 |
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| MX369674B (es) | 2019-11-15 |
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| US20180179517A9 (en) | 2018-06-28 |
| US20150209753A1 (en) | 2015-07-30 |
| SG10201803094QA (en) | 2018-06-28 |
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