ES2714786T3 - Cápsula gastrointestinal - Google Patents
Cápsula gastrointestinal Download PDFInfo
- Publication number
- ES2714786T3 ES2714786T3 ES07805598T ES07805598T ES2714786T3 ES 2714786 T3 ES2714786 T3 ES 2714786T3 ES 07805598 T ES07805598 T ES 07805598T ES 07805598 T ES07805598 T ES 07805598T ES 2714786 T3 ES2714786 T3 ES 2714786T3
- Authority
- ES
- Spain
- Prior art keywords
- cgi
- capsule
- gastrointestinal
- stirring mechanism
- segment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000002775 capsule Substances 0.000 title claims abstract description 24
- 230000002496 gastric effect Effects 0.000 title claims abstract description 15
- 230000007246 mechanism Effects 0.000 claims abstract description 13
- 238000003756 stirring Methods 0.000 claims abstract description 12
- 230000000694 effects Effects 0.000 claims abstract description 3
- 238000001514 detection method Methods 0.000 claims description 15
- 238000013019 agitation Methods 0.000 claims description 13
- 239000000463 material Substances 0.000 claims description 5
- 230000004913 activation Effects 0.000 description 24
- 238000001994 activation Methods 0.000 description 24
- 210000004913 chyme Anatomy 0.000 description 8
- 210000002784 stomach Anatomy 0.000 description 8
- 230000035939 shock Effects 0.000 description 7
- 230000005294 ferromagnetic effect Effects 0.000 description 6
- 239000007787 solid Substances 0.000 description 6
- 206010010774 Constipation Diseases 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 230000010287 polarization Effects 0.000 description 5
- 230000037406 food intake Effects 0.000 description 4
- 210000001035 gastrointestinal tract Anatomy 0.000 description 4
- 210000002429 large intestine Anatomy 0.000 description 4
- 230000037023 motor activity Effects 0.000 description 4
- 208000008589 Obesity Diseases 0.000 description 3
- 230000003111 delayed effect Effects 0.000 description 3
- 210000003608 fece Anatomy 0.000 description 3
- 210000000936 intestine Anatomy 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 210000000813 small intestine Anatomy 0.000 description 3
- 230000000638 stimulation Effects 0.000 description 3
- 238000002604 ultrasonography Methods 0.000 description 3
- 230000001154 acute effect Effects 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 125000004122 cyclic group Chemical group 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 239000010408 film Substances 0.000 description 2
- 235000020824 obesity Nutrition 0.000 description 2
- 230000002572 peristaltic effect Effects 0.000 description 2
- 229920000747 poly(lactic acid) Polymers 0.000 description 2
- 229920001606 poly(lactic acid-co-glycolic acid) Polymers 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 229920002595 Dielectric elastomer Polymers 0.000 description 1
- 206010021518 Impaired gastric emptying Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 238000012084 abdominal surgery Methods 0.000 description 1
- 210000003815 abdominal wall Anatomy 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- ADCXHZZSUADYMI-UHFFFAOYSA-N cadmium lithium Chemical compound [Li].[Cd] ADCXHZZSUADYMI-UHFFFAOYSA-N 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 208000012696 congenital leptin deficiency Diseases 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 229920001746 electroactive polymer Polymers 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 230000005176 gastrointestinal motility Effects 0.000 description 1
- 208000001288 gastroparesis Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 208000001022 morbid obesity Diseases 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 210000004303 peritoneum Anatomy 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 210000001187 pylorus Anatomy 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 239000012815 thermoplastic material Substances 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
- A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
- A61H23/0254—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with rotary motor
- A61H23/0263—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with rotary motor using rotating unbalanced masses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H21/00—Massage devices for cavities of the body, e.g. nose, ears and anus ; Vibration or percussion related aspects A61H23/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
- A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H2205/00—Devices for specific parts of the body
- A61H2205/08—Trunk
- A61H2205/083—Abdomen
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rehabilitation Therapy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Otolaryngology (AREA)
- Reproductive Health (AREA)
- Percussion Or Vibration Massage (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Surgical Instruments (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84520006P | 2006-09-18 | 2006-09-18 | |
| PCT/IL2007/001139 WO2008035329A2 (en) | 2006-09-18 | 2007-09-17 | Gastrointestinal capsule |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2714786T3 true ES2714786T3 (es) | 2019-05-30 |
Family
ID=39200951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07805598T Active ES2714786T3 (es) | 2006-09-18 | 2007-09-17 | Cápsula gastrointestinal |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US9078799B2 (enExample) |
| EP (1) | EP2073779B1 (enExample) |
| JP (2) | JP5075204B2 (enExample) |
| CN (1) | CN101516314B (enExample) |
| AU (1) | AU2007298473A1 (enExample) |
| BR (1) | BRPI0714733A2 (enExample) |
| CA (1) | CA2662070C (enExample) |
| ES (1) | ES2714786T3 (enExample) |
| TR (1) | TR201902226T4 (enExample) |
| WO (1) | WO2008035329A2 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11026822B2 (en) | 2006-01-13 | 2021-06-08 | C. R. Bard, Inc. | Stent delivery system |
| GB0615658D0 (en) | 2006-08-07 | 2006-09-13 | Angiomed Ag | Hand-held actuator device |
| US9078799B2 (en) * | 2006-09-18 | 2015-07-14 | Vibrant Ltd. | Gastrointestinal capsule |
| GB0713497D0 (en) | 2007-07-11 | 2007-08-22 | Angiomed Ag | Device for catheter sheath retraction |
| CN103025319B (zh) * | 2010-03-10 | 2015-07-01 | 因卡伯实验室有限责任公司 | 用于利用可吞咽式药剂递送装置递送到肠道内腔中的治疗剂制剂 |
| GB201017834D0 (en) | 2010-10-21 | 2010-12-01 | Angiomed Ag | System to deliver a bodily implant |
| US9155677B2 (en) | 2011-08-09 | 2015-10-13 | Franklin R. Lacy | System for gastrointestinal and vascular atrophy engineering to restore normal youthful bodily functions |
| GB201202706D0 (en) * | 2012-02-16 | 2012-04-04 | Vibrant Ltd | gastrointestinal capsule |
| AU2014224165B2 (en) * | 2012-02-16 | 2017-10-19 | Vibrant Ltd | Gastrointestinal capsule and treatment method |
| US20200315541A1 (en) * | 2012-02-16 | 2020-10-08 | Vibrant Ltd. | Gastrointestinal Capsule and Treatment Method |
| US20150065926A1 (en) * | 2012-04-12 | 2015-03-05 | Sony Corporation | Capsule-type medical device and system |
| CN105877980B (zh) | 2015-04-27 | 2019-04-19 | 上海安翰医疗技术有限公司 | 消化道内部理疗装置及其控制方法 |
| US11116658B2 (en) | 2015-06-28 | 2021-09-14 | Oberon Sciences Ilan Ltd. | Devices for gastrointestinal stimulation and uses thereof |
| CN105342825B (zh) * | 2015-11-18 | 2018-07-06 | 上海麦添医疗科技有限公司 | 可吞入消化道按摩装置及其加工方法 |
| CN105434155A (zh) * | 2015-12-30 | 2016-03-30 | 上海是源医疗仪器科技有限公司 | 一种可调节胃肠动力的智能振动胶囊系统 |
| CN205459754U (zh) * | 2016-01-28 | 2016-08-17 | 上海和初医疗科技有限公司 | 消化道胶囊 |
| US10478373B2 (en) | 2016-04-18 | 2019-11-19 | Ankon Medical Technologies (Shanghai) Co., Ltd | In vivo device and method of using the same |
| US10500127B2 (en) | 2016-04-18 | 2019-12-10 | Ankon Medical Technologies (Shanghai) Co., Ltd. | Vivo device and method of using the same |
| CN106175744B (zh) * | 2016-07-18 | 2019-01-01 | 合肥凯利光电科技有限公司 | 消化道动力检测仪振动状态下抗干扰性能的工业检测方法 |
| CN106175745B (zh) * | 2016-07-18 | 2019-01-01 | 合肥凯利光电科技有限公司 | 消化道动力检测仪温湿环境中抗干扰性能的工业检测方法 |
| CN106264450B (zh) * | 2016-07-18 | 2019-04-02 | 合肥凯利光电科技有限公司 | 消化道动力检测仪低温环境中工作稳定性的工业检测方法 |
| US20240156366A1 (en) * | 2016-09-21 | 2024-05-16 | Vibrant Ltd. | Gastrointestinal treatment system including a personalized vibrating capsule, and method of use thereof |
| US11504024B2 (en) | 2018-03-30 | 2022-11-22 | Vibrant Ltd. | Gastrointestinal treatment system including a vibrating capsule, and method of use thereof |
| CN207908510U (zh) | 2016-09-21 | 2018-09-25 | 维布兰特公司 | 安装在抽水马桶上的传感器 |
| GB2554354B (en) | 2016-09-21 | 2021-06-02 | Vibrant Ltd | Systems for adaptive treatment of disorders in the gastrointestinal tract |
| US20210196296A1 (en) * | 2017-01-30 | 2021-07-01 | Vibrant Ltd. | Method for treating conditions of the gi tract using a vibrating ingestible capsule |
| US10888277B1 (en) | 2017-01-30 | 2021-01-12 | Vibrant Ltd | Method for treating diarrhea and reducing Bristol stool scores using a vibrating ingestible capsule |
| US20220409139A1 (en) * | 2017-01-30 | 2022-12-29 | Vibrant Ltd. | Method for treating a gastric bloating sensation using a vibrating ingestible capsule |
| US10905378B1 (en) | 2017-01-30 | 2021-02-02 | Vibrant Ltd | Method for treating gastroparesis using a vibrating ingestible capsule |
| CN106924024B (zh) * | 2017-04-18 | 2018-03-09 | 李伟 | 奶牛瘤胃迟缓按摩装置 |
| KR102797753B1 (ko) | 2018-03-30 | 2025-04-18 | 바이브런트 리미티드 | 진동 캡슐을 포함하는 위장 치료 시스템 |
| US10537720B2 (en) | 2018-04-09 | 2020-01-21 | Vibrant Ltd. | Method of enhancing absorption of ingested medicaments for treatment of parkinsonism |
| US11638678B1 (en) | 2018-04-09 | 2023-05-02 | Vibrant Ltd. | Vibrating capsule system and treatment method |
| US12083303B2 (en) | 2019-01-21 | 2024-09-10 | Vibrant Ltd. | Device and method for delivering a flowable ingestible medicament into the gastrointestinal tract of a user |
| US20210023357A1 (en) * | 2018-04-09 | 2021-01-28 | Vibrant Ltd. | Vibrating capsule for enhancing absorption of ingested medicaments |
| US11510590B1 (en) | 2018-05-07 | 2022-11-29 | Vibrant Ltd. | Methods and systems for treating gastrointestinal disorders |
| CA3125091A1 (en) | 2019-01-03 | 2020-07-09 | Vibrant Ltd. | Device and method for delivering an ingestible medicament into the gastrointestinal tract of a user |
| GB201900780D0 (en) | 2019-01-21 | 2019-03-06 | Vibrant Ltd | Device and method for delivering a flowable ingestible medicament into the gastrointestinal tract of a user |
| GB201901470D0 (en) * | 2019-02-04 | 2019-03-27 | Vibrant Ltd | Vibrating capsule for gastrointestinal treatment, and method of use thereof |
| CN110038220B (zh) * | 2019-05-30 | 2024-02-09 | 上海麦添医疗科技有限公司 | 一种消化道理疗装置 |
| CN111568730B (zh) * | 2020-05-20 | 2022-02-11 | 合肥工业大学 | 一种肠道按摩机器 |
| CN111525653B (zh) * | 2020-06-01 | 2022-12-06 | 上海安翰医疗技术有限公司 | 振动胶囊及其供电方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3485235A (en) * | 1967-12-04 | 1969-12-23 | Ronald Felson | Capsule for the study and treatment of the digestive tract |
| JPS57163309A (en) * | 1981-04-01 | 1982-10-07 | Olympus Optical Co Ltd | Capsule apparatus for medical use |
| JPH03162857A (ja) * | 1989-02-24 | 1991-07-12 | Teranishi Denki Seisakusho:Kk | マッサージ機 |
| EA001070B1 (ru) * | 1996-04-01 | 2000-10-30 | Валерий Иванович КОБОЗЕВ | Электростимулятор желудочно-кишечного тракта |
| US8636648B2 (en) * | 1999-03-01 | 2014-01-28 | West View Research, Llc | Endoscopic smart probe |
| JP2001112710A (ja) * | 1999-10-20 | 2001-04-24 | Asahi Optical Co Ltd | カプセル内視鏡 |
| WO2002007598A1 (en) * | 2000-07-24 | 2002-01-31 | Motorola, Inc. | Ingestible electronic capsule |
| KR100417163B1 (ko) * | 2001-11-12 | 2004-02-05 | 한국과학기술연구원 | 마이크로 캡슐형 로봇 |
| KR100482275B1 (ko) * | 2002-08-09 | 2005-04-13 | 한국과학기술연구원 | 마이크로 캡슐형 로봇 |
| US6776165B2 (en) | 2002-09-12 | 2004-08-17 | The Regents Of The University Of California | Magnetic navigation system for diagnosis, biopsy and drug delivery vehicles |
| JP4503930B2 (ja) * | 2003-01-30 | 2010-07-14 | オリンパス株式会社 | 医療装置 |
| US7623904B2 (en) * | 2003-08-06 | 2009-11-24 | Olympus Corporation | Medical apparatus, medical apparatus guide system, capsule type medical apparatus, and capsule type medical apparatus guide apparatus |
| US8306592B2 (en) * | 2003-12-19 | 2012-11-06 | Olympus Corporation | Capsule medical device |
| EP1807036A4 (en) * | 2004-11-02 | 2014-04-16 | Jimmyjane Inc | BODY VIBRATOR WITH REPLACEABLE ENGINE |
| WO2006070374A2 (en) * | 2004-12-30 | 2006-07-06 | Given Imaging Ltd. | System and method for assembling a swallowable sensing device |
| EP1871327B1 (en) * | 2005-03-16 | 2009-12-23 | Unilever PLC | A device for washing and creating massaging vibrations within a bar of soap |
| US20060276729A1 (en) * | 2005-06-07 | 2006-12-07 | Reed Pamela S | Method and device for treating obesity by suppressing appetite and hunger using vibration |
| US8021384B2 (en) * | 2005-07-26 | 2011-09-20 | Ram Weiss | Extending intrabody capsule |
| AU2006273679B2 (en) * | 2005-07-26 | 2012-05-03 | Menachem P. Weiss | Extending intrabody capsule |
| US20070238940A1 (en) | 2005-11-23 | 2007-10-11 | Omar Amirana | Vibrator pill for gastrointestinal disorders |
| US9078799B2 (en) * | 2006-09-18 | 2015-07-14 | Vibrant Ltd. | Gastrointestinal capsule |
| GB201202706D0 (en) * | 2012-02-16 | 2012-04-04 | Vibrant Ltd | gastrointestinal capsule |
| US10537720B2 (en) * | 2018-04-09 | 2020-01-21 | Vibrant Ltd. | Method of enhancing absorption of ingested medicaments for treatment of parkinsonism |
-
2007
- 2007-09-17 US US12/310,201 patent/US9078799B2/en active Active
- 2007-09-17 CN CN200780034629.6A patent/CN101516314B/zh active Active
- 2007-09-17 JP JP2009527961A patent/JP5075204B2/ja active Active
- 2007-09-17 EP EP07805598.5A patent/EP2073779B1/en active Active
- 2007-09-17 WO PCT/IL2007/001139 patent/WO2008035329A2/en not_active Ceased
- 2007-09-17 AU AU2007298473A patent/AU2007298473A1/en not_active Abandoned
- 2007-09-17 ES ES07805598T patent/ES2714786T3/es active Active
- 2007-09-17 TR TR2019/02226T patent/TR201902226T4/tr unknown
- 2007-09-17 CA CA2662070A patent/CA2662070C/en active Active
- 2007-09-17 BR BRPI0714733-3A patent/BRPI0714733A2/pt not_active IP Right Cessation
-
2010
- 2010-09-09 JP JP2010201675A patent/JP5240866B2/ja active Active
-
2015
- 2015-06-07 US US14/732,733 patent/US9532923B2/en active Active
-
2016
- 2016-11-23 US US15/359,731 patent/US11197798B2/en active Active
-
2021
- 2021-11-08 US US17/453,876 patent/US20220054352A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP5075204B2 (ja) | 2012-11-21 |
| US9078799B2 (en) | 2015-07-14 |
| EP2073779A4 (en) | 2016-07-20 |
| US9532923B2 (en) | 2017-01-03 |
| JP2010503451A (ja) | 2010-02-04 |
| AU2007298473A1 (en) | 2008-03-27 |
| EP2073779A2 (en) | 2009-07-01 |
| US20150313792A1 (en) | 2015-11-05 |
| US20170135897A1 (en) | 2017-05-18 |
| WO2008035329A2 (en) | 2008-03-27 |
| BRPI0714733A2 (pt) | 2013-05-21 |
| US20220054352A1 (en) | 2022-02-24 |
| CN101516314B (zh) | 2014-05-21 |
| JP2011045723A (ja) | 2011-03-10 |
| EP2073779B1 (en) | 2018-12-26 |
| JP5240866B2 (ja) | 2013-07-17 |
| TR201902226T4 (tr) | 2019-03-21 |
| WO2008035329A3 (en) | 2009-05-07 |
| US11197798B2 (en) | 2021-12-14 |
| US20090318841A1 (en) | 2009-12-24 |
| CA2662070C (en) | 2015-11-17 |
| CA2662070A1 (en) | 2008-03-27 |
| CN101516314A (zh) | 2009-08-26 |
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