ES2708826T3 - Detección de la predisposición genética a afecciones asociadas a la osteoartritis - Google Patents

Detección de la predisposición genética a afecciones asociadas a la osteoartritis Download PDF

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Publication number
ES2708826T3
ES2708826T3 ES15193948T ES15193948T ES2708826T3 ES 2708826 T3 ES2708826 T3 ES 2708826T3 ES 15193948 T ES15193948 T ES 15193948T ES 15193948 T ES15193948 T ES 15193948T ES 2708826 T3 ES2708826 T3 ES 2708826T3
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ES
Spain
Prior art keywords
subject
disease
osteoarthritis
progression
allele
Prior art date
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Active
Application number
ES15193948T
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English (en)
Spanish (es)
Inventor
Jack F Bukowski
Nazneen Aziz
Hwa-Ying Wang
Kenneth Huttner
Steven B Abramson
Mukundan Attur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seaport Diagnostics Inc
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Orig3n Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES15193948T 2008-05-02 2009-05-04 Detección de la predisposición genética a afecciones asociadas a la osteoartritis Active ES2708826T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4999208P 2008-05-02 2008-05-02
US11874408P 2008-12-01 2008-12-01

Publications (1)

Publication Number Publication Date
ES2708826T3 true ES2708826T3 (es) 2019-04-11

Family

ID=41210581

Family Applications (2)

Application Number Title Priority Date Filing Date
ES15193948T Active ES2708826T3 (es) 2008-05-02 2009-05-04 Detección de la predisposición genética a afecciones asociadas a la osteoartritis
ES09740020.4T Active ES2561316T3 (es) 2008-05-02 2009-05-04 Detección de la predisposición genética a estados asociados con la osteoartritis

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES09740020.4T Active ES2561316T3 (es) 2008-05-02 2009-05-04 Detección de la predisposición genética a estados asociados con la osteoartritis

Country Status (9)

Country Link
US (2) US20100098775A1 (enExample)
EP (3) EP3467126A1 (enExample)
JP (3) JP5762282B2 (enExample)
AU (1) AU2009242490B2 (enExample)
CA (1) CA2723239C (enExample)
DK (2) DK2283156T3 (enExample)
ES (2) ES2708826T3 (enExample)
NZ (1) NZ589034A (enExample)
WO (1) WO2009135218A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2708826T3 (es) * 2008-05-02 2019-04-11 Orig3N Inc Detección de la predisposición genética a afecciones asociadas a la osteoartritis
US20120115137A1 (en) * 2010-08-31 2012-05-10 Kornman Kenneth S Methods of Predicting Osteoarthritis
US10221456B2 (en) * 2012-08-06 2019-03-05 Merck Patent Gmbh Genetic markers for predicting responsiveness to FPG-18 compound
CN104755629A (zh) * 2012-08-06 2015-07-01 默克专利有限公司 软骨疾病的预后生物标记
CA3011363A1 (en) 2016-01-12 2017-07-20 Interleukin Genetics, Inc. Methods for predicting response to treatment
US10329620B2 (en) 2017-01-12 2019-06-25 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
HUE058848T2 (hu) 2017-09-29 2022-09-28 Merck Patent Gmbh FGF-18 vegyületre vonatkozó válaszkészség elõrejelzésére szolgáló gyulladásos biomarkerek
SI3687558T1 (sl) 2017-09-29 2022-08-31 Merck Patent Gmbh Presnovni biooznačevalci za napovedovanje odzivnosti na spojino FGF-18
EP3850113B1 (en) * 2018-09-10 2024-04-03 Merck Patent GmbH Markers useful in enrichment strategies for the treatment of osteoarthritis
US12370240B2 (en) 2018-11-28 2025-07-29 Genascence Corporation Methods and compositions for treating osteoarthritis
CA3142662A1 (en) 2019-06-06 2020-12-10 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
US20220265773A1 (en) * 2019-08-02 2022-08-25 New York University Methods and compositions for treating arthritis
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8311018D0 (en) 1983-04-22 1983-05-25 Amersham Int Plc Detecting mutations in dna
US4998617A (en) * 1986-09-15 1991-03-12 Laura Lupton Inc Facial cosmetic liquid make up kit
US4968607A (en) * 1987-11-25 1990-11-06 Immunex Corporation Interleukin-1 receptors
US5459039A (en) 1989-05-12 1995-10-17 Duke University Methods for mapping genetic mutations
FR2650840B1 (fr) 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
DE69433811T2 (de) 1993-01-07 2005-06-23 Sequenom, Inc., San Diego Dns - sequenzierung durch massenspektronomie
US5593826A (en) 1993-03-22 1997-01-14 Perkin-Elmer Corporation, Applied Biosystems, Inc. Enzymatic ligation of 3'amino-substituted oligonucleotides
US5686246A (en) * 1995-08-03 1997-11-11 Kornman; Kenneth S. Detecting genetic predisposition to periodontal disease
US5942390A (en) 1996-01-12 1999-08-24 Cedars-Sinai Medical Center Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism
US5698399A (en) * 1996-04-05 1997-12-16 Duff; Gordon W. Detecting genetic predisposition for osteoporosis
GB9621129D0 (en) * 1996-10-10 1996-11-27 Duff Gordon W Detecting genetic predisposition to sight-threatening diabetic retinopathy
GB9706359D0 (en) * 1997-03-27 1997-05-14 Gemini International Holdings Polymorphisms of an il-1 receptor antagonist gene
GB9711040D0 (en) * 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
WO2003064600A2 (en) * 2002-01-25 2003-08-07 Interleukin Genetics, Inc. The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes
EP2186913B1 (en) * 2003-11-26 2016-02-10 Celera Corporation Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
CA2631675A1 (en) * 2005-11-30 2007-06-21 The University Of North Carolina At Chapel Hill Identification of genetic polymorphic variants associated with somatosensory disorders and methods of using the same
ES2708826T3 (es) * 2008-05-02 2019-04-11 Orig3N Inc Detección de la predisposición genética a afecciones asociadas a la osteoartritis
US9037472B2 (en) 2012-04-20 2015-05-19 Nuance Communications, Inc. Method and system for facilitating communications for a user transaction

Also Published As

Publication number Publication date
AU2009242490A1 (en) 2009-11-05
EP2283156A2 (en) 2011-02-16
US20160340734A1 (en) 2016-11-24
JP2011520433A (ja) 2011-07-21
JP2018038436A (ja) 2018-03-15
JP5762282B2 (ja) 2015-08-12
AU2009242490B2 (en) 2015-01-22
NZ589034A (en) 2012-10-26
US20100098775A1 (en) 2010-04-22
EP3467126A1 (en) 2019-04-10
WO2009135218A3 (en) 2010-04-01
JP6263499B2 (ja) 2018-01-17
CA2723239C (en) 2020-07-21
EP3059323B1 (en) 2018-12-12
CA2723239A1 (en) 2009-11-05
DK3059323T3 (en) 2019-03-04
EP2283156B1 (en) 2015-11-11
EP3059323A1 (en) 2016-08-24
JP2015211677A (ja) 2015-11-26
ES2561316T3 (es) 2016-02-25
WO2009135218A2 (en) 2009-11-05
DK2283156T3 (en) 2016-02-15

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