ES2691306T3 - Procedimientos y composiciones para detectar mutaciones en el gen PI3KCA (PIK3CA) humano - Google Patents

Procedimientos y composiciones para detectar mutaciones en el gen PI3KCA (PIK3CA) humano Download PDF

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Publication number
ES2691306T3
ES2691306T3 ES14709926.1T ES14709926T ES2691306T3 ES 2691306 T3 ES2691306 T3 ES 2691306T3 ES 14709926 T ES14709926 T ES 14709926T ES 2691306 T3 ES2691306 T3 ES 2691306T3
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artificial sequence
dna
note
source
description
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English (en)
Spanish (es)
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Alison Tsan
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ES14709926.1T 2013-03-13 2014-03-12 Procedimientos y composiciones para detectar mutaciones en el gen PI3KCA (PIK3CA) humano Active ES2691306T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361780017P 2013-03-13 2013-03-13
US201361780017P 2013-03-13
PCT/EP2014/054766 WO2014140061A2 (en) 2013-03-13 2014-03-12 Methods and compositions for detecting mutations in the human pi3kca (pik3ca) gene

Publications (1)

Publication Number Publication Date
ES2691306T3 true ES2691306T3 (es) 2018-11-26

Family

ID=50277211

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14709926.1T Active ES2691306T3 (es) 2013-03-13 2014-03-12 Procedimientos y composiciones para detectar mutaciones en el gen PI3KCA (PIK3CA) humano

Country Status (7)

Country Link
US (2) US20140272961A1 (enExample)
EP (1) EP2971075B1 (enExample)
JP (1) JP6453781B2 (enExample)
CN (2) CN105229171A (enExample)
CA (1) CA2899712C (enExample)
ES (1) ES2691306T3 (enExample)
WO (1) WO2014140061A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201206486D0 (en) * 2012-04-12 2012-05-30 Sequessome Technology Holdings Ltd Vesicular formulations and uses thereof
WO2018094569A1 (zh) * 2016-11-22 2018-05-31 深圳华大基因研究院 多肽及其应用
CN109913481B (zh) * 2019-04-24 2020-04-03 无锡市第五人民医院 PIK3CA基因g.179224821G>A突变及其在乳腺癌辅助诊断中的应用
KR102813811B1 (ko) * 2020-03-27 2025-05-30 주식회사 젠큐릭스 Pik3ca 돌연변이 검출용 조성물 및 이를 포함하는 키트
CN111363827A (zh) * 2020-04-30 2020-07-03 北京和合医学诊断技术股份有限公司 用于检测pik3ca基因突变的引物组及其应用方法
CN114410790B (zh) * 2022-01-27 2024-04-12 湖南大学 一种用于检测ctDNA的生物传感检测系统及其检测方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2663248T3 (es) * 2004-03-02 2018-04-11 The Johns Hopkins University Mutaciones del gen de PIK3CA en cánceres humanos
GB2453173A (en) * 2007-09-28 2009-04-01 Dxs Ltd Polynucleotide primers
JP5624044B2 (ja) * 2008-10-20 2014-11-12 エフ.ホフマン−ラ ロシュアーゲーF.Hoffmann−La Roche Aktiengesellschaft 改善されたアレル−特異的増幅
US20100286143A1 (en) * 2009-04-24 2010-11-11 Dora Dias-Santagata Methods and materials for genetic analysis of tumors
US9238832B2 (en) * 2009-12-11 2016-01-19 Roche Molecular Systems, Inc. Allele-specific amplification of nucleic acids
EP3246332B1 (en) * 2010-01-12 2019-07-10 Siemens Healthcare Diagnostics Inc. Oligonucleotides and methods for detecting pik3ca mutations
CN102234685B (zh) * 2010-04-23 2014-08-27 益善生物技术股份有限公司 一种pik3ca基因突变检测液相芯片
KR101825121B1 (ko) * 2010-08-13 2018-02-06 주식회사 파나진 Pna 기반의 실시간 pcr 클램핑을 이용한 pik3ca 돌연변이 검출 방법 및 키트
JP6050820B2 (ja) * 2011-09-23 2016-12-21 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 改良された対立遺伝子特異的pcrのためのg−クランプの使用

Also Published As

Publication number Publication date
CA2899712A1 (en) 2014-09-18
JP2016510982A (ja) 2016-04-14
WO2014140061A3 (en) 2014-10-30
US20160160297A1 (en) 2016-06-09
EP2971075A2 (en) 2016-01-20
US20140272961A1 (en) 2014-09-18
EP2971075B1 (en) 2018-08-15
WO2014140061A2 (en) 2014-09-18
JP6453781B2 (ja) 2019-01-16
CA2899712C (en) 2021-01-05
CN105229171A (zh) 2016-01-06
CN108130373A (zh) 2018-06-08

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