ES2666458T3 - Macrociclos peptidomiméticos - Google Patents
Macrociclos peptidomiméticos Download PDFInfo
- Publication number
- ES2666458T3 ES2666458T3 ES09736335.2T ES09736335T ES2666458T3 ES 2666458 T3 ES2666458 T3 ES 2666458T3 ES 09736335 T ES09736335 T ES 09736335T ES 2666458 T3 ES2666458 T3 ES 2666458T3
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- polypeptide
- amino acid
- micromolar
- human serum
- cases
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| EP3170835A1 (en) * | 2006-12-14 | 2017-05-24 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
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| CN109627287A (zh) | 2007-02-23 | 2019-04-16 | 爱勒让治疗公司 | 三唑大环系统 |
| CA2682174C (en) | 2007-03-28 | 2021-04-06 | President And Fellows Of Harvard College | Stitched polypeptides |
| CA2710964A1 (en) * | 2007-12-31 | 2009-09-11 | New York University | Control of viral-host membrane fusion with hydrogen bond surrogate-based artificial helices |
| CN101980718A (zh) * | 2008-02-08 | 2011-02-23 | 爱勒让治疗公司 | 治疗性的拟肽大环化合物 |
| US20110144303A1 (en) * | 2008-04-08 | 2011-06-16 | Aileron Therapeutics, Inc. | Biologically Active Peptidomimetic Macrocycles |
| US20110144306A1 (en) * | 2008-07-23 | 2011-06-16 | President And Fellows Of Harvard College | Ligation of stapled polypeptides |
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| US8957026B2 (en) | 2010-09-22 | 2015-02-17 | President And Fellows Of Harvard College | Beta-catenin targeting peptides and uses thereof |
| WO2012051405A1 (en) | 2010-10-13 | 2012-04-19 | Bristol-Myers Squibb Company | Methods for preparing macrocycles and macrocycle stabilized peptides |
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| US9487562B2 (en) | 2011-06-17 | 2016-11-08 | President And Fellows Of Harvard College | Stabilized polypeptides as regulators of RAB GTPase function |
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| SMT202100337T1 (it) | 2012-09-26 | 2021-07-12 | Harvard College | Peptidi graffati bloccati con prolina e loro usi |
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| EP4212180A1 (en) | 2013-12-18 | 2023-07-19 | The Scripps Research Institute | Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof |
| US10533039B2 (en) | 2014-05-21 | 2020-01-14 | President And Fellows Of Harvard College | Ras inhibitory peptides and uses thereof |
| BR112017005598A2 (pt) | 2014-09-24 | 2017-12-12 | Aileron Therapeutics Inc | macrociclos peptidomiméticos e usos dos mesmos |
| SG10201902598VA (en) | 2014-09-24 | 2019-04-29 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and formulations thereof |
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| JP6729579B2 (ja) * | 2015-06-25 | 2020-07-22 | Ａｇｃ株式会社 | 撥水剤組成物、撥水剤組成物の製造方法および物品 |
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2015
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| US8399405B2 (en) | 2013-03-19 |
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| AU2009294877A1 (en) | 2010-03-25 |
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| EP2342222A1 (en) | 2011-07-13 |
| AU2009294877C1 (en) | 2015-05-07 |
| BRPI0918948A2 (pt) | 2015-12-15 |
| US20120172311A1 (en) | 2012-07-05 |
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