ES2662027T3 - Procedimiento y aparato para la determinación de parámetros de contaminantes en una solución líquida - Google Patents
Procedimiento y aparato para la determinación de parámetros de contaminantes en una solución líquida Download PDFInfo
- Publication number
- ES2662027T3 ES2662027T3 ES07700123.8T ES07700123T ES2662027T3 ES 2662027 T3 ES2662027 T3 ES 2662027T3 ES 07700123 T ES07700123 T ES 07700123T ES 2662027 T3 ES2662027 T3 ES 2662027T3
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- ES
- Spain
- Prior art keywords
- solution
- container
- individual
- laser
- scanner
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 238000000034 method Methods 0.000 title claims abstract description 21
- 239000006193 liquid solution Substances 0.000 title claims abstract description 8
- 239000000356 contaminant Substances 0.000 title abstract description 6
- 239000002245 particle Substances 0.000 claims abstract description 25
- 230000003287 optical effect Effects 0.000 claims abstract description 7
- 238000012545 processing Methods 0.000 claims abstract description 3
- 239000003344 environmental pollutant Substances 0.000 claims abstract 3
- 231100000719 pollutant Toxicity 0.000 claims abstract 3
- 230000005284 excitation Effects 0.000 claims description 10
- 238000004811 liquid chromatography Methods 0.000 claims description 4
- 238000001917 fluorescence detection Methods 0.000 claims description 2
- 238000002356 laser light scattering Methods 0.000 claims 1
- 239000006185 dispersion Substances 0.000 abstract description 4
- 239000000523 sample Substances 0.000 description 15
- 238000004458 analytical method Methods 0.000 description 10
- 238000001514 detection method Methods 0.000 description 6
- 239000013307 optical fiber Substances 0.000 description 3
- 238000012800 visualization Methods 0.000 description 3
- 238000000149 argon plasma sintering Methods 0.000 description 2
- 238000005515 capillary zone electrophoresis Methods 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000007717 exclusion Effects 0.000 description 2
- 238000001825 field-flow fractionation Methods 0.000 description 2
- 238000001506 fluorescence spectroscopy Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000005497 microtitration Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000004566 IR spectroscopy Methods 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000004520 agglutination Effects 0.000 description 1
- 239000000538 analytical sample Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000005251 capillar electrophoresis Methods 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000002983 circular dichroism Methods 0.000 description 1
- 238000002296 dynamic light scattering Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000004255 ion exchange chromatography Methods 0.000 description 1
- 238000001155 isoelectric focusing Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 238000001370 static light scattering Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0205—Investigating particle size or size distribution by optical means
- G01N15/0227—Investigating particle size or size distribution by optical means using imaging; using holography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
- G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6402—Atomic fluorescence; Laser induced fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N2015/0294—Particle shape
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/19—Dichroism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
- G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Length Measuring Devices By Optical Means (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CH2007/000025 WO2008086632A1 (en) | 2007-01-19 | 2007-01-19 | Method and apparatus for detecting and registering properties of samples |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2662027T3 true ES2662027T3 (es) | 2018-04-05 |
Family
ID=38522765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07700123.8T Active ES2662027T3 (es) | 2007-01-19 | 2007-01-19 | Procedimiento y aparato para la determinación de parámetros de contaminantes en una solución líquida |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9417176B2 (enExample) |
| EP (1) | EP2106541B1 (enExample) |
| JP (1) | JP2010516999A (enExample) |
| CN (1) | CN101583863A (enExample) |
| ES (1) | ES2662027T3 (enExample) |
| PL (1) | PL2106541T3 (enExample) |
| WO (1) | WO2008086632A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2232700B1 (en) | 2007-12-21 | 2014-08-13 | Dts Llc | System for adjusting perceived loudness of audio signals |
| EP2404157B1 (en) * | 2009-03-04 | 2021-02-24 | Malvern Panalytical Limited | Method for measuring particle size by dynamic or static light scattering measurement |
| US8538042B2 (en) | 2009-08-11 | 2013-09-17 | Dts Llc | System for increasing perceived loudness of speakers |
| US9312829B2 (en) | 2012-04-12 | 2016-04-12 | Dts Llc | System for adjusting loudness of audio signals in real time |
| US10132736B2 (en) | 2012-05-24 | 2018-11-20 | Abbvie Inc. | Methods for inspection of protein particles in a liquid beneficial agent |
| CN117253055A (zh) * | 2016-10-28 | 2023-12-19 | 贝克曼库尔特有限公司 | 物质准备评估系统 |
| LU100777B1 (de) * | 2018-04-23 | 2019-10-23 | Cytena Gmbh | Verfahren zum Untersuchen einer Flüssigkeit, die wenigstens eine Zelle und/oder wenigstens ein Partikel enthält |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3624835A (en) * | 1968-11-21 | 1971-11-30 | Science Spectrum | Microparticle analyzer employing a spherical detector array |
| US4221961A (en) * | 1978-10-23 | 1980-09-09 | Industrial Automation Corporation | Electronic bottle inspector having particle and liquid detection capabilities |
| EP0056413A1 (en) | 1980-07-24 | 1982-07-28 | Labsystems Oy | Method and apparatus for the measurement of the properties of an agglutination |
| WO1989007255A1 (en) | 1988-02-03 | 1989-08-10 | Cetus Corporation | Apparatus and method for detecting hemagglutinaion reactions |
| JP2667526B2 (ja) * | 1989-08-12 | 1997-10-27 | 科学技術振興事業団 | 高感度多波長発光蛍光分光方法及び装置 |
| JPH03197840A (ja) * | 1989-12-26 | 1991-08-29 | Canon Inc | 粒子解析装置 |
| JP2826366B2 (ja) * | 1990-04-12 | 1998-11-18 | 株式会社日立製作所 | 蛍光検出型電気泳動装置 |
| DK17791D0 (da) * | 1991-02-01 | 1991-02-01 | Novo Nordisk As | Beholderinspektion |
| JPH0572179A (ja) * | 1991-09-10 | 1993-03-23 | Hitachi Ltd | 核酸、蛋白の2次元蛍光像検出装置 |
| DE4223269A1 (de) | 1992-07-16 | 1994-01-20 | Krieg Gunther | Verfahren und Vorrichtung zur schnellen Identifikation von Molekülverbindungen, insbesondere von Flüssigkeiten in Getränkeflaschen |
| US5436979A (en) * | 1992-08-21 | 1995-07-25 | Eastman Kodak Company | Process for detecting and mapping dirt on the surface of a photographic element |
| US5486693A (en) * | 1994-02-17 | 1996-01-23 | Thermedics Detection Inc. | Detection of turbid contaminants in containers by detecting scattered radiant energy |
| JP3559648B2 (ja) | 1996-04-23 | 2004-09-02 | 株式会社日立製作所 | キャピラリーアレー電気泳動装置 |
| CN1262667C (zh) * | 1996-04-25 | 2006-07-05 | 詹尼康科学公司 | 利用颗粒标记物检测分析物 |
| US6914250B2 (en) * | 1997-03-07 | 2005-07-05 | Clare Chemical Research, Inc. | Fluorometric detection using visible light |
| GB9816088D0 (en) * | 1998-07-23 | 1998-09-23 | Axis Biochemicals Asa | System |
| JP2002221498A (ja) * | 2000-11-24 | 2002-08-09 | Sukiyan Technol:Kk | 異物検査システム |
| JP2002228586A (ja) * | 2001-01-31 | 2002-08-14 | Hitachi Ltd | 蛍光測定装置及び蛍光測定方法 |
| US20030133119A1 (en) * | 2002-01-17 | 2003-07-17 | Bachur Nicholas R. | Rapid imaging of particles in a large fluid volume through flow cell imaging |
| ES2703694T3 (es) | 2004-08-19 | 2019-03-12 | Becton Dickinson Co | Aparato para la realización de mediciones ópticas en botellas de hemocultivo |
-
2007
- 2007-01-19 JP JP2009545784A patent/JP2010516999A/ja active Pending
- 2007-01-19 WO PCT/CH2007/000025 patent/WO2008086632A1/en not_active Ceased
- 2007-01-19 PL PL07700123T patent/PL2106541T3/pl unknown
- 2007-01-19 US US12/522,877 patent/US9417176B2/en not_active Expired - Fee Related
- 2007-01-19 EP EP07700123.8A patent/EP2106541B1/en not_active Not-in-force
- 2007-01-19 ES ES07700123.8T patent/ES2662027T3/es active Active
- 2007-01-19 CN CNA2007800499751A patent/CN101583863A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2106541A1 (en) | 2009-10-07 |
| US20100102247A1 (en) | 2010-04-29 |
| US9417176B2 (en) | 2016-08-16 |
| EP2106541B1 (en) | 2017-12-13 |
| CN101583863A (zh) | 2009-11-18 |
| WO2008086632A8 (en) | 2009-08-13 |
| JP2010516999A (ja) | 2010-05-20 |
| WO2008086632A1 (en) | 2008-07-24 |
| PL2106541T3 (pl) | 2018-05-30 |
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