JP2010516999A - 試料の特性を検出し自記する為の方法と装置 - Google Patents

試料の特性を検出し自記する為の方法と装置 Download PDF

Info

Publication number
JP2010516999A
JP2010516999A JP2009545784A JP2009545784A JP2010516999A JP 2010516999 A JP2010516999 A JP 2010516999A JP 2009545784 A JP2009545784 A JP 2009545784A JP 2009545784 A JP2009545784 A JP 2009545784A JP 2010516999 A JP2010516999 A JP 2010516999A
Authority
JP
Japan
Prior art keywords
sample
laser
laser beam
scanner
fluorescence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009545784A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010516999A5 (enExample
Inventor
トゥドール・アービンテ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JP2010516999A publication Critical patent/JP2010516999A/ja
Publication of JP2010516999A5 publication Critical patent/JP2010516999A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0227—Investigating particle size or size distribution by optical means using imaging; using holography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6402—Atomic fluorescence; Laser induced fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N2015/0294—Particle shape
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/19—Dichroism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Length Measuring Devices By Optical Means (AREA)
JP2009545784A 2007-01-19 2007-01-19 試料の特性を検出し自記する為の方法と装置 Pending JP2010516999A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CH2007/000025 WO2008086632A1 (en) 2007-01-19 2007-01-19 Method and apparatus for detecting and registering properties of samples

Publications (2)

Publication Number Publication Date
JP2010516999A true JP2010516999A (ja) 2010-05-20
JP2010516999A5 JP2010516999A5 (enExample) 2012-08-30

Family

ID=38522765

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009545784A Pending JP2010516999A (ja) 2007-01-19 2007-01-19 試料の特性を検出し自記する為の方法と装置

Country Status (7)

Country Link
US (1) US9417176B2 (enExample)
EP (1) EP2106541B1 (enExample)
JP (1) JP2010516999A (enExample)
CN (1) CN101583863A (enExample)
ES (1) ES2662027T3 (enExample)
PL (1) PL2106541T3 (enExample)
WO (1) WO2008086632A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8315398B2 (en) 2007-12-21 2012-11-20 Dts Llc System for adjusting perceived loudness of audio signals
US8538042B2 (en) 2009-08-11 2013-09-17 Dts Llc System for increasing perceived loudness of speakers
US9312829B2 (en) 2012-04-12 2016-04-12 Dts Llc System for adjusting loudness of audio signals in real time
CN112119339A (zh) * 2018-04-23 2020-12-22 生德奈股份有限公司 用于检查包含至少一种细胞和/或至少一种颗粒的液体的方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6059872B2 (ja) * 2009-03-04 2017-01-18 マルベルン インスツルメンツ リミテッドＭａｌｖｅｒｎ Ｉｎｓｔｒｕｍｅｎｔｓ Ｌｉｍｉｔｅｄ 粒子特性の測定
US10132736B2 (en) 2012-05-24 2018-11-20 Abbvie Inc. Methods for inspection of protein particles in a liquid beneficial agent
EP3532985B1 (en) * 2016-10-28 2023-07-12 Beckman Coulter, Inc. Substance preparation evaluation system

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0372247A (ja) * 1989-08-12 1991-03-27 Res Dev Corp Of Japan 高感度多波長発光蛍光分光方法及び装置
JPH03197840A (ja) * 1989-12-26 1991-08-29 Canon Inc 粒子解析装置
JPH03293557A (ja) * 1990-04-12 1991-12-25 Hitachi Ltd 蛍光検出型電気泳動装置
JPH0572179A (ja) * 1991-09-10 1993-03-23 Hitachi Ltd 核酸、蛋白の２次元蛍光像検出装置
JPH06505333A (ja) * 1991-02-01 1994-06-16 ノボ　ノルディスク　アクティーゼルスカブ 液体充填の容器を検査する方法と装置
US5486693A (en) * 1994-02-17 1996-01-23 Thermedics Detection Inc. Detection of turbid contaminants in containers by detecting scattered radiant energy
JP2002521660A (ja) * 1998-07-23 2002-07-16 アクシス−シールド・エーエスエー 凝集検定
JP2002228586A (ja) * 2001-01-31 2002-08-14 Hitachi Ltd 蛍光測定装置及び蛍光測定方法
JP2003294604A (ja) * 2002-01-17 2003-10-15 Becton Dickinson & Co フローセルイメージングによる粒子の画像化装置及びその方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3624835A (en) * 1968-11-21 1971-11-30 Science Spectrum Microparticle analyzer employing a spherical detector array
US4221961A (en) * 1978-10-23 1980-09-09 Industrial Automation Corporation Electronic bottle inspector having particle and liquid detection capabilities
WO1982000354A1 (en) * 1980-07-24 1982-02-04 Oy Labsystems Method and apparatus for the measurement of the properties of an agglutination
WO1989007255A1 (en) * 1988-02-03 1989-08-10 Cetus Corporation Apparatus and method for detecting hemagglutinaion reactions
DE4223269A1 (de) * 1992-07-16 1994-01-20 Krieg Gunther Verfahren und Vorrichtung zur schnellen Identifikation von Molekülverbindungen, insbesondere von Flüssigkeiten in Getränkeflaschen
US5436979A (en) * 1992-08-21 1995-07-25 Eastman Kodak Company Process for detecting and mapping dirt on the surface of a photographic element
JP3559648B2 (ja) * 1996-04-23 2004-09-02 株式会社日立製作所 キャピラリーアレー電気泳動装置
CA2253710A1 (en) * 1996-04-25 1997-10-30 Spectrametrix Inc. Analyte assay using particulate labels
US6914250B2 (en) * 1997-03-07 2005-07-05 Clare Chemical Research, Inc. Fluorometric detection using visible light
JP2002221498A (ja) * 2000-11-24 2002-08-09 Sukiyan Technol:Kk 異物検査システム
US7643134B2 (en) * 2004-08-19 2010-01-05 Becton, Dickinson And Company Apparatus for performing optical measurements on blood culture bottles

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0372247A (ja) * 1989-08-12 1991-03-27 Res Dev Corp Of Japan 高感度多波長発光蛍光分光方法及び装置
JPH03197840A (ja) * 1989-12-26 1991-08-29 Canon Inc 粒子解析装置
JPH03293557A (ja) * 1990-04-12 1991-12-25 Hitachi Ltd 蛍光検出型電気泳動装置
JPH06505333A (ja) * 1991-02-01 1994-06-16 ノボ　ノルディスク　アクティーゼルスカブ 液体充填の容器を検査する方法と装置
JPH0572179A (ja) * 1991-09-10 1993-03-23 Hitachi Ltd 核酸、蛋白の２次元蛍光像検出装置
US5486693A (en) * 1994-02-17 1996-01-23 Thermedics Detection Inc. Detection of turbid contaminants in containers by detecting scattered radiant energy
JP2002521660A (ja) * 1998-07-23 2002-07-16 アクシス−シールド・エーエスエー 凝集検定
JP2002228586A (ja) * 2001-01-31 2002-08-14 Hitachi Ltd 蛍光測定装置及び蛍光測定方法
JP2003294604A (ja) * 2002-01-17 2003-10-15 Becton Dickinson & Co フローセルイメージングによる粒子の画像化装置及びその方法

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8315398B2 (en) 2007-12-21 2012-11-20 Dts Llc System for adjusting perceived loudness of audio signals
US8538042B2 (en) 2009-08-11 2013-09-17 Dts Llc System for increasing perceived loudness of speakers
US9820044B2 (en) 2009-08-11 2017-11-14 Dts Llc System for increasing perceived loudness of speakers
US10299040B2 (en) 2009-08-11 2019-05-21 Dts, Inc. System for increasing perceived loudness of speakers
US9312829B2 (en) 2012-04-12 2016-04-12 Dts Llc System for adjusting loudness of audio signals in real time
US9559656B2 (en) 2012-04-12 2017-01-31 Dts Llc System for adjusting loudness of audio signals in real time
CN112119339A (zh) * 2018-04-23 2020-12-22 生德奈股份有限公司 用于检查包含至少一种细胞和/或至少一种颗粒的液体的方法
JP2021522474A (ja) * 2018-04-23 2021-08-30 ツィテナ ゲーエムベーハーＣｙｔｅｎａ Ｇｍｂｈ 少なくとも１つの細胞および／または少なくとも１つの粒子を含む液体を検査するための方法
US11624694B2 (en) 2018-04-23 2023-04-11 Cytena Gmbh Method for examining a liquid which contains at least one cell and/or at least one particle

Also Published As

Publication number Publication date
WO2008086632A8 (en) 2009-08-13
EP2106541B1 (en) 2017-12-13
US9417176B2 (en) 2016-08-16
EP2106541A1 (en) 2009-10-07
CN101583863A (zh) 2009-11-18
ES2662027T3 (es) 2018-04-05
PL2106541T3 (pl) 2018-05-30
US20100102247A1 (en) 2010-04-29
WO2008086632A1 (en) 2008-07-24

Similar Documents

Publication Publication Date Title
EP2948756B1 (en) Optical measuring apparatus and method for the analysis of samples contained in liquid drops
EP3071951B1 (en) Optical engine for flow cytometer, flow cytometer system and methods of use
EP1935983B1 (en) Method for determination of biological particles in blood
US9417176B2 (en) Method and apparatus for detecting and registering properties of samples
JP2008281571A (ja) 共鳴光散乱粒子標識から発生する信号を読み取るための装置
JP5174035B2 (ja) 二次元配列画像化
Gessner et al. Identification of biotic and abiotic particles by using a combination of optical tweezers and in situ Raman spectroscopy
US10156520B2 (en) Array based sample characterization
US9488579B2 (en) Optical measuring apparatus and method for the analysis of samples contained in liquid drops
JP2007524389A (ja) 病原微生物検出のための広視野法
EP0592624A4 (en) Diagnostic microbiological testing apparatus and method
US20220326129A1 (en) Systems and methods for identifying protein aggregates in biotherapeutics
US20150308944A1 (en) Optical measuring apparatus and method for the analysis of samples contained in liquid drops
US20200379227A1 (en) Method For Analyzing Fluorescent Particles in an Immunoassay
EP1472913B1 (en) Analysis method
EP3770580B1 (en) Fine particle measurement device
JPH01102342A (ja) 蛍光顕微分光装置
KR102441156B1 (ko) 다파장 광원을 이용한 다중 분석장치
JP2004226408A (ja) サンプルの反応を観察する装置と方法
JP2001004318A (ja) 光路長測定装置
WO2025006995A2 (en) Contaminant sensing interrogator (csi) for biologics and complex fluids
JP2003021593A (ja) 検体検査装置

Legal Events

Date Code Title Description
A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120117

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120412

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120419

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120515

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120522

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120608

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120615

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120706

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20120706

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130204

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130418

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130425

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130604

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130611

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130704

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20131216