CN101583863A - 用于检测和登记样品性质的方法和设备 - Google Patents

用于检测和登记样品性质的方法和设备 Download PDF

Info

Publication number
CN101583863A
CN101583863A CNA2007800499751A CN200780049975A CN101583863A CN 101583863 A CN101583863 A CN 101583863A CN A2007800499751 A CNA2007800499751 A CN A2007800499751A CN 200780049975 A CN200780049975 A CN 200780049975A CN 101583863 A CN101583863 A CN 101583863A
Authority
CN
China
Prior art keywords
sample
laser beam
laser
scanner
shows
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800499751A
Other languages
English (en)
Chinese (zh)
Inventor
图德·阿尔温特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CN101583863A publication Critical patent/CN101583863A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0227—Investigating particle size or size distribution by optical means using imaging; using holography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6402—Atomic fluorescence; Laser induced fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N2015/0294—Particle shape
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/19—Dichroism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Length Measuring Devices By Optical Means (AREA)
CNA2007800499751A 2007-01-19 2007-01-19 用于检测和登记样品性质的方法和设备 Pending CN101583863A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CH2007/000025 WO2008086632A1 (en) 2007-01-19 2007-01-19 Method and apparatus for detecting and registering properties of samples

Publications (1)

Publication Number Publication Date
CN101583863A true CN101583863A (zh) 2009-11-18

Family

ID=38522765

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800499751A Pending CN101583863A (zh) 2007-01-19 2007-01-19 用于检测和登记样品性质的方法和设备

Country Status (7)

Country Link
US (1) US9417176B2 (enExample)
EP (1) EP2106541B1 (enExample)
JP (1) JP2010516999A (enExample)
CN (1) CN101583863A (enExample)
ES (1) ES2662027T3 (enExample)
PL (1) PL2106541T3 (enExample)
WO (1) WO2008086632A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104487816A (zh) * 2012-05-24 2015-04-01 艾伯维公司 用于检测有益制剂中的颗粒的系统及方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2232700B1 (en) 2007-12-21 2014-08-13 Dts Llc System for adjusting perceived loudness of audio signals
EP2404157B1 (en) * 2009-03-04 2021-02-24 Malvern Panalytical Limited Method for measuring particle size by dynamic or static light scattering measurement
US8538042B2 (en) 2009-08-11 2013-09-17 Dts Llc System for increasing perceived loudness of speakers
US9312829B2 (en) 2012-04-12 2016-04-12 Dts Llc System for adjusting loudness of audio signals in real time
BR112019008270A8 (pt) * 2016-10-28 2023-04-11 Beckman Coulter Inc Sistema de avaliação de preparação de substância
LU100777B1 (de) * 2018-04-23 2019-10-23 Cytena Gmbh Verfahren zum Untersuchen einer Flüssigkeit, die wenigstens eine Zelle und/oder wenigstens ein Partikel enthält

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3624835A (en) * 1968-11-21 1971-11-30 Science Spectrum Microparticle analyzer employing a spherical detector array
US4221961A (en) * 1978-10-23 1980-09-09 Industrial Automation Corporation Electronic bottle inspector having particle and liquid detection capabilities
WO1982000354A1 (en) * 1980-07-24 1982-02-04 Oy Labsystems Method and apparatus for the measurement of the properties of an agglutination
WO1989007255A1 (en) * 1988-02-03 1989-08-10 Cetus Corporation Apparatus and method for detecting hemagglutinaion reactions
JP2667526B2 (ja) * 1989-08-12 1997-10-27 科学技術振興事業団 高感度多波長発光蛍光分光方法及び装置
JPH03197840A (ja) * 1989-12-26 1991-08-29 Canon Inc 粒子解析装置
JP2826366B2 (ja) * 1990-04-12 1998-11-18 株式会社日立製作所 蛍光検出型電気泳動装置
DK17791D0 (da) * 1991-02-01 1991-02-01 Novo Nordisk As Beholderinspektion
JPH0572179A (ja) * 1991-09-10 1993-03-23 Hitachi Ltd 核酸、蛋白の２次元蛍光像検出装置
DE4223269A1 (de) * 1992-07-16 1994-01-20 Krieg Gunther Verfahren und Vorrichtung zur schnellen Identifikation von Molekülverbindungen, insbesondere von Flüssigkeiten in Getränkeflaschen
US5436979A (en) * 1992-08-21 1995-07-25 Eastman Kodak Company Process for detecting and mapping dirt on the surface of a photographic element
US5486693A (en) 1994-02-17 1996-01-23 Thermedics Detection Inc. Detection of turbid contaminants in containers by detecting scattered radiant energy
JP3559648B2 (ja) * 1996-04-23 2004-09-02 株式会社日立製作所 キャピラリーアレー電気泳動装置
IL126544A (en) * 1996-04-25 2004-08-31 Genicon Sciences Inc Analyte assay using scattered-light detectable particles
US6914250B2 (en) * 1997-03-07 2005-07-05 Clare Chemical Research, Inc. Fluorometric detection using visible light
GB9816088D0 (en) 1998-07-23 1998-09-23 Axis Biochemicals Asa System
JP2002221498A (ja) 2000-11-24 2002-08-09 Sukiyan Technol:Kk 異物検査システム
JP2002228586A (ja) * 2001-01-31 2002-08-14 Hitachi Ltd 蛍光測定装置及び蛍光測定方法
US20030133119A1 (en) * 2002-01-17 2003-07-17 Bachur Nicholas R. Rapid imaging of particles in a large fluid volume through flow cell imaging
JP4921368B2 (ja) * 2004-08-19 2012-04-25 ベクトン・ディキンソン・アンド・カンパニー 光学的測定を血液培養瓶に対して行う装置

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104487816A (zh) * 2012-05-24 2015-04-01 艾伯维公司 用于检测有益制剂中的颗粒的系统及方法
US10126226B2 (en) 2012-05-24 2018-11-13 Abbvie Inc. Systems for inspection of protein particles in a liquid beneficial agent
US10132736B2 (en) 2012-05-24 2018-11-20 Abbvie Inc. Methods for inspection of protein particles in a liquid beneficial agent

Also Published As

Publication number Publication date
PL2106541T3 (pl) 2018-05-30
WO2008086632A1 (en) 2008-07-24
EP2106541B1 (en) 2017-12-13
JP2010516999A (ja) 2010-05-20
EP2106541A1 (en) 2009-10-07
ES2662027T3 (es) 2018-04-05
US9417176B2 (en) 2016-08-16
US20100102247A1 (en) 2010-04-29
WO2008086632A8 (en) 2009-08-13

Similar Documents

Publication Publication Date Title
EP2948756B1 (en) Optical measuring apparatus and method for the analysis of samples contained in liquid drops
US10156520B2 (en) Array based sample characterization
Bloomfield et al. Non-invasive identification of incoming raw pharmaceutical materials using Spatially Offset Raman Spectroscopy
JP5174035B2 (ja) 二次元配列画像化
US9417176B2 (en) Method and apparatus for detecting and registering properties of samples
JP2008281571A (ja) 共鳴光散乱粒子標識から発生する信号を読み取るための装置
US10670454B2 (en) System for optically monitoring operating conditions in a sample analyzing apparatus
US9488579B2 (en) Optical measuring apparatus and method for the analysis of samples contained in liquid drops
US9488576B2 (en) Optical measuring apparatus and method for the analysis of samples contained in liquid drops
US20220326129A1 (en) Systems and methods for identifying protein aggregates in biotherapeutics
EP3438644B1 (en) Cell analysis system
JP2017538943A (ja) クロマトグラフ試料を光学的に検知する方法及び装置
EP3770580B1 (en) Fine particle measurement device
CN112119339B (zh) 检查包含至少一种细胞和/或至少一种颗粒的液体的方法
JP2004226408A (ja) サンプルの反応を観察する装置と方法
CN104237199A (zh) 一种基于扩散方式的拉曼检测系统和方法
JP7649322B2 (ja) ラマン分析用プレート、ラマン分析装置、分析システム、及びラマン分析方法
KR100691528B1 (ko) 단백질 칩 분석용 표면 플라즈몬 주사 현미경 장치
US20050006594A1 (en) Simple systems for accurately detecting and measuring only fluorescent radiation from a sample in a plastic test tube
JP2003014645A (ja) 検体検査装置

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C12 Rejection of a patent application after its publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20091118