ES2624448T3 - Implantes poliméricos de agonistas alfa-2 adrenérgicos biodegradables - Google Patents

Implantes poliméricos de agonistas alfa-2 adrenérgicos biodegradables Download PDF

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Publication number
ES2624448T3
ES2624448T3 ES09799446.1T ES09799446T ES2624448T3 ES 2624448 T3 ES2624448 T3 ES 2624448T3 ES 09799446 T ES09799446 T ES 09799446T ES 2624448 T3 ES2624448 T3 ES 2624448T3
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ES
Spain
Prior art keywords
implant
polymer
release
implants
eye
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09799446.1T
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English (en)
Spanish (es)
Inventor
Lon T. Spada
Alazar N. Ghebremeskel
Michael R. Robinson
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Allergan Inc
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Allergan Inc
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Publication of ES2624448T3 publication Critical patent/ES2624448T3/es
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
ES09799446.1T 2008-11-17 2009-11-06 Implantes poliméricos de agonistas alfa-2 adrenérgicos biodegradables Active ES2624448T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US272548 2002-10-16
US12/272,548 US9095506B2 (en) 2008-11-17 2008-11-17 Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof
PCT/US2009/063490 WO2010056598A2 (en) 2008-11-17 2009-11-06 Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof

Publications (1)

Publication Number Publication Date
ES2624448T3 true ES2624448T3 (es) 2017-07-14

Family

ID=41698087

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09799446.1T Active ES2624448T3 (es) 2008-11-17 2009-11-06 Implantes poliméricos de agonistas alfa-2 adrenérgicos biodegradables

Country Status (7)

Country Link
US (7) US9095506B2 (https=)
EP (1) EP2355795B1 (https=)
JP (2) JP5580832B2 (https=)
AU (3) AU2009314266A1 (https=)
CA (1) CA2743837C (https=)
ES (1) ES2624448T3 (https=)
WO (1) WO2010056598A2 (https=)

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Also Published As

Publication number Publication date
US9522113B2 (en) 2016-12-20
US20200069578A1 (en) 2020-03-05
CA2743837C (en) 2017-03-28
US9861576B2 (en) 2018-01-09
CA2743837A1 (en) 2010-05-20
US20170100334A1 (en) 2017-04-13
AU2018202557A1 (en) 2018-05-10
US10842739B2 (en) 2020-11-24
JP2014184348A (ja) 2014-10-02
US9095506B2 (en) 2015-08-04
EP2355795A2 (en) 2011-08-17
US10471004B2 (en) 2019-11-12
JP2012509264A (ja) 2012-04-19
EP2355795B1 (en) 2017-01-04
JP5580832B2 (ja) 2014-08-27
AU2018202557B2 (en) 2020-02-27
US20180353426A1 (en) 2018-12-13
AU2009314266A1 (en) 2010-05-20
US20160030334A1 (en) 2016-02-04
AU2016204582A1 (en) 2016-07-21
US20230285279A1 (en) 2023-09-14
WO2010056598A3 (en) 2010-12-23
US20100124565A1 (en) 2010-05-20
WO2010056598A2 (en) 2010-05-20
US20210161809A1 (en) 2021-06-03

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