ES2608604T3 - Uso de MVA para tratar el cáncer de próstata - Google Patents
Uso de MVA para tratar el cáncer de próstata Download PDFInfo
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- ES2608604T3 ES2608604T3 ES08839145.3T ES08839145T ES2608604T3 ES 2608604 T3 ES2608604 T3 ES 2608604T3 ES 08839145 T ES08839145 T ES 08839145T ES 2608604 T3 ES2608604 T3 ES 2608604T3
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A61K2039/525—Virus
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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- A61K2039/5256—Virus expressing foreign proteins
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- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
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- A61K2039/80—Vaccine for a specifically defined cancer
- A61K2039/884—Vaccine for a specifically defined cancer prostate
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
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- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/023—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a poxvirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/04—Uses of viruses as vector in vivo
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Developmental Biology & Embryology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pregnancy & Childbirth (AREA)
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- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US96089307P | 2007-10-18 | 2007-10-18 | |
| US960893P | 2007-10-18 | ||
| PCT/US2008/080229 WO2009052328A1 (en) | 2007-10-18 | 2008-10-16 | Use of mva to treat prostate cancer |
Publications (1)
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| ES2608604T3 true ES2608604T3 (es) | 2017-04-12 |
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| ES08839145.3T Active ES2608604T3 (es) | 2007-10-18 | 2008-10-16 | Uso de MVA para tratar el cáncer de próstata |
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| JP (1) | JP5669581B2 (OSRAM) |
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| RU (1) | RU2499606C2 (OSRAM) |
| WO (1) | WO2009052328A1 (OSRAM) |
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| US6136311A (en) | 1996-05-06 | 2000-10-24 | Cornell Research Foundation, Inc. | Treatment and diagnosis of cancer |
| PT1335987E (pt) * | 2000-11-23 | 2006-05-31 | Bavarian Nordic As | Variante do virus vacina modificado ancara |
| JP2009531324A (ja) | 2006-03-20 | 2009-09-03 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 癌標的化のための操作された抗前立腺幹細胞抗原（ｐｓｃａ）抗体 |
| US8940298B2 (en) * | 2007-09-04 | 2015-01-27 | The Regents Of The University Of California | High affinity anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting and detection |
| EP2209498A2 (en) * | 2007-10-03 | 2010-07-28 | Cornell University | Treatment of proliferative disorders using antibodies to psma |
| EP2207564B1 (en) * | 2007-10-18 | 2016-10-05 | Bavarian Nordic A/S | Use of mva to treat prostate cancer |
| US20100069616A1 (en) * | 2008-08-06 | 2010-03-18 | The Regents Of The University Of California | Engineered antibody-nanoparticle conjugates |
| EP2398504B1 (en) * | 2009-02-17 | 2018-11-28 | Cornell Research Foundation, Inc. | Methods and kits for diagnosis of cancer and prediction of therapeutic value |
| GB2484058A (en) * | 2009-12-01 | 2012-04-04 | Uni Konstanz | Prostate cancer DNA vaccine |
| BR112012012887A2 (pt) | 2009-12-02 | 2017-05-02 | Imaginab Inc | minicorpo e cys-diabody (cysdb) codificados por sequência de nucleótidos, respectivo uso e métodos de diagnósticos e de tratamento de câncer associado com a expressão de psma num sujeito. |
| JP6312141B2 (ja) | 2012-03-30 | 2018-04-18 | 国立大学法人京都大学 | 前立腺がん検査用尿中バイオマーカー |
| MX2016005656A (es) * | 2013-11-01 | 2016-07-14 | Pfizer | Vectores para expresion de antigenos asociados a prostata. |
| US20160081314A1 (en) | 2014-09-19 | 2016-03-24 | Regeneron Pharmaceuticals, Inc. | Chimeric Antigen Receptors |
| CA2977660A1 (en) | 2015-02-25 | 2016-09-15 | Memorial Sloan-Kettering Cancer Center | Use of inactivated nonreplicating modified vaccinia virus ankara (mva) as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors |
| JP6936153B2 (ja) | 2015-04-17 | 2021-09-15 | メモリアル スローン ケタリング キャンサー センター | Ｍｖａ又はｍｖａδｅ３ｌの固形腫瘍免疫療法剤としての使用 |
| MX2018001566A (es) | 2015-08-07 | 2019-04-25 | Imaginab Inc | Construcciones de union a antigeno para moleculas diana. |
| CA3000275A1 (en) * | 2015-10-02 | 2017-04-06 | University Of Copenhagen | Small molecules blocking histone reader domains |
| FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
| GB201520550D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| GB201520568D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd | Peptides |
| GB201520570D0 (en) * | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
| CN108883203A (zh) * | 2016-02-12 | 2018-11-23 | 麦迪逊疫苗公司 | 癌症疗法 |
| AU2017222686B2 (en) | 2016-02-25 | 2021-12-23 | Memorial Sloan Kettering Cancer Center | Replication competent attenuated vaccinia viruses with deletion of thymidine kinase with and without the expression of human Flt3L or GM-CSF for cancer immunotherapy |
| EP3419662A4 (en) | 2016-02-25 | 2019-09-18 | Memorial Sloan Kettering Cancer Center | HUMAN FLT3L EXPRESSIVE RECOMBINANT MVA OR MVADELE3L AND USE THEREOF AS IMMUNOTHERAPEUTICS AGAINST SOLID TUMORS |
| CA3021947A1 (en) * | 2016-04-26 | 2017-11-02 | Sumitomo Dainippon Pharma Co., Ltd. | Substituted purine derivative |
| RS66700B1 (sr) | 2016-06-03 | 2025-05-30 | Regeneron Pharma | Glodari koji eksprimiraju egzogenu terminalnu dezoksinukleotidil transferazu |
| SG11201810631SA (en) * | 2016-06-03 | 2018-12-28 | Etubics Corp | Compositions and methods for tumor vaccination using prostate cancer-associated antigens |
| CN106084027A (zh) * | 2016-06-24 | 2016-11-09 | 安徽未名细胞治疗有限公司 | 特异性肿瘤抗原EphA2的CTL识别表位肽及其应用 |
| CN106119231A (zh) * | 2016-06-24 | 2016-11-16 | 安徽未名细胞治疗有限公司 | 一种肿瘤抗原psa的ctl识别表位肽及其应用 |
| WO2018147960A1 (en) | 2017-02-08 | 2018-08-16 | Imaginab, Inc. | Extension sequences for diabodies |
| CN111107872A (zh) | 2017-05-12 | 2020-05-05 | 纪念斯隆-凯特林癌症中心 | 有用于癌症免疫疗法的牛痘病毒突变体 |
| US10925947B2 (en) * | 2018-06-29 | 2021-02-23 | Immatics Biotechnologies Gmbh | A*03 restricted peptides for use in immunotherapy against cancers and related methods |
| JP7480126B2 (ja) | 2018-09-15 | 2024-05-09 | メモリアル スローン ケタリング キャンサー センター | がん免疫療法のための、組換えポックスウイルス |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| WO2020247859A2 (en) * | 2019-06-07 | 2020-12-10 | Oregon Health & Science University | Tumor-associated antigen-specific t cell responses |
| MX2022005980A (es) | 2019-11-18 | 2022-09-07 | Janssen Biotech Inc | Vacunas basadas en calr y jak2 mutantes y sus usos. |
| JP2023521194A (ja) * | 2020-04-13 | 2023-05-23 | ヤンセン バイオテツク，インコーポレーテツド | Ｐｓｍａ及びｓｔｅａｐ１ワクチン並びにそれらの使用 |
| US12295997B2 (en) * | 2020-07-06 | 2025-05-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| FR3160186A1 (fr) | 2024-03-13 | 2025-09-19 | Odimma Therapeutics | Vecteur non-viral pour transcription augmentee |
Family Cites Families (14)
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| JP3939746B2 (ja) * | 1991-07-25 | 2007-07-04 | バイオジェン・アイデック・インコーポレイテッド | 細胞毒性ｔ−リンパ球応答の誘導 |
| JPH09504000A (ja) * | 1993-08-11 | 1997-04-22 | ジェナー テクノロジーズ | 前立腺癌ワクチン |
| US6045802A (en) * | 1994-10-03 | 2000-04-04 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule |
| US6165460A (en) * | 1995-07-10 | 2000-12-26 | Therion Biologics Corporation | Generation of immune responses to prostate-specific antigen (PSA) |
| WO1998004689A1 (en) * | 1995-07-31 | 1998-02-05 | Urocor, Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate disease |
| CA2286477A1 (en) | 1997-04-11 | 1998-10-22 | Dendreon Corporation | Composition and method for inducing an immune response against tumour-related antigens |
| ES2222728T3 (es) | 1998-10-05 | 2005-02-01 | Pharmexa A/S | Procedimiento de vacunacion terapeutica. |
| CA2354024C (en) * | 1998-12-09 | 2009-12-22 | Jeffrey Schlom | A recombinant vector expressing multiple costimulatory molecules and uses thereof |
| PT1335987E (pt) | 2000-11-23 | 2006-05-31 | Bavarian Nordic As | Variante do virus vacina modificado ancara |
| WO2003073828A2 (en) * | 2002-03-01 | 2003-09-12 | Applied Immune Technologies | Immunotherapy for prostate cancer using recombinant bacille calmette-guerin expressing prostate specific antigens |
| MXPA04011194A (es) * | 2002-05-16 | 2005-02-14 | Bavarian Nordic As | Virus de viruela recombinantes que expresan los genes homologos introducidos dentro del genoma viral de la viruela. |
| WO2005019464A1 (en) * | 2003-08-21 | 2005-03-03 | Virax Development Pty Ltd | Poxvirus vector encoding prostate specific antigens for treatment of prostate cancer |
| BRPI0401465A (pt) | 2004-04-20 | 2006-02-21 | Embria Informatica Ltda | sistema para administrar interações entre usuários e aplicações de software em um ambiente web |
| EP2207564B1 (en) | 2007-10-18 | 2016-10-05 | Bavarian Nordic A/S | Use of mva to treat prostate cancer |
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- 2008-10-16 RU RU2010115220/15A patent/RU2499606C2/ru not_active IP Right Cessation
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Also Published As
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| US7867483B2 (en) | 2011-01-11 |
| KR101648087B1 (ko) | 2016-08-17 |
| AU2008312444A1 (en) | 2009-04-23 |
| CA2702586A1 (en) | 2009-04-23 |
| KR20100109545A (ko) | 2010-10-08 |
| WO2009052328A1 (en) | 2009-04-23 |
| EP2207564B1 (en) | 2016-10-05 |
| DK2207564T3 (en) | 2017-01-16 |
| JP5669581B2 (ja) | 2015-02-12 |
| KR20160065985A (ko) | 2016-06-09 |
| HK1149709A1 (en) | 2011-10-14 |
| RU2499606C2 (ru) | 2013-11-27 |
| US8377688B2 (en) | 2013-02-19 |
| CN101888853B (zh) | 2013-03-13 |
| RU2010115220A (ru) | 2011-11-27 |
| IL204541A (en) | 2015-02-26 |
| EP2207564A1 (en) | 2010-07-21 |
| AU2008312444B2 (en) | 2014-02-06 |
| CN101888853A (zh) | 2010-11-17 |
| CA2702586C (en) | 2017-08-01 |
| NZ601827A (en) | 2014-01-31 |
| WO2009052328A8 (en) | 2009-07-02 |
| US20090104225A1 (en) | 2009-04-23 |
| US20110008386A1 (en) | 2011-01-13 |
| JP2011500718A (ja) | 2011-01-06 |
| NZ584042A (en) | 2012-09-28 |
| IL204541A0 (en) | 2010-11-30 |
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