ES2600789T3 - Tratamiento de infecciones por VIH-1 latentes usando auranofina o trióxido de arsénico - Google Patents
Tratamiento de infecciones por VIH-1 latentes usando auranofina o trióxido de arsénico Download PDFInfo
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- ES2600789T3 ES2600789T3 ES09759664.7T ES09759664T ES2600789T3 ES 2600789 T3 ES2600789 T3 ES 2600789T3 ES 09759664 T ES09759664 T ES 09759664T ES 2600789 T3 ES2600789 T3 ES 2600789T3
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- hiv
- cells
- auranofin
- hdaci
- treatment
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A—HUMAN NECESSITIES
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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- A—HUMAN NECESSITIES
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0819857A GB0819857D0 (en) | 2008-10-29 | 2008-10-29 | Antiviral therapy |
| GB0819857 | 2008-10-29 | ||
| GB0908952A GB0908952D0 (en) | 2009-05-22 | 2009-05-22 | Antiviral therapy |
| GB0908952 | 2009-05-22 | ||
| PCT/EP2009/007958 WO2010049182A2 (en) | 2008-10-29 | 2009-10-29 | Treatment of retroviral reservoirs exploiting oxidative stress |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2600789T3 true ES2600789T3 (es) | 2017-02-10 |
Family
ID=41596151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09759664.7T Active ES2600789T3 (es) | 2008-10-29 | 2009-10-29 | Tratamiento de infecciones por VIH-1 latentes usando auranofina o trióxido de arsénico |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US8785493B2 (OSRAM) |
| EP (1) | EP2349245B1 (OSRAM) |
| JP (1) | JP5779503B2 (OSRAM) |
| ES (1) | ES2600789T3 (OSRAM) |
| PL (1) | PL2349245T3 (OSRAM) |
| WO (1) | WO2010049182A2 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| ES2620027T3 (es) | 2008-09-03 | 2017-06-27 | Biomarin Pharmaceutical Inc. | Composiciones que incluyen derivados del ácido 6-aminohexanoico como inhibidores de HDAC |
| US9719069B2 (en) | 2009-01-27 | 2017-08-01 | University Of Utah Research Foundation | Methods and compositions relating to viral latency |
| GB201011921D0 (en) * | 2010-07-15 | 2010-09-01 | Sutan Anwar | Method for gas chromatography analysis and maintenance |
| US9540395B2 (en) | 2011-02-28 | 2017-01-10 | Biomarin Pharmaceutical Inc. | Histone deacetylase inhibitors |
| US8957066B2 (en) | 2011-02-28 | 2015-02-17 | Biomarin Pharmaceutical Inc. | Histone deacetylase inhibitors |
| US10059723B2 (en) | 2011-02-28 | 2018-08-28 | Biomarin Pharmaceutical Inc. | Histone deacetylase inhibitors |
| CN102727523A (zh) * | 2011-04-02 | 2012-10-17 | 复旦大学 | 一种具有抗hiv潜伏作用的药物及其用途 |
| KR20150132345A (ko) | 2013-03-15 | 2015-11-25 | 바이오마린 파머수티컬 인크. | Hdac 저해제 |
| EP3008043A2 (en) * | 2013-06-14 | 2016-04-20 | University Of Utah Research Foundation | Triazol-1-ol analogs anti-retroviral latency drugs |
| EP3470536A1 (en) * | 2013-10-01 | 2019-04-17 | The J. David Gladstone Institutes | Compositions, systems and methods for gene expression noise drug screening and uses thereof |
| US12220420B2 (en) * | 2016-05-03 | 2025-02-11 | Galera Labs, Llc | Combination therapy for cancer treatment |
| BR112019019491A2 (pt) | 2017-03-23 | 2020-04-22 | Istituto Superiore di Sanità | sulfoximina butionina e um metalofármaco para tratamento de câncer, hiv ou uma doença reumática |
| US20230285441A1 (en) * | 2020-04-15 | 2023-09-14 | Georgia State University Research Foundation, Inc. | Treatment of coronavirus infections with auranofin |
| CN116478070B (zh) * | 2022-06-23 | 2024-09-27 | 山东第一医科大学(山东省医学科学院) | 一种化合物、药物组合物及其在扩张血管或抗病毒领域的应用 |
| CN116947763A (zh) * | 2023-07-11 | 2023-10-27 | 郑州大学 | 2-巯基-5-氰基-6-芳基嘧啶杂环类化合物、制备方法和应用 |
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| US7232685B2 (en) * | 2001-12-19 | 2007-06-19 | The Regents Of The Universtiy Of California | Cell lines with latent immunodeficiency virus and methods of use thereof |
| AU2002351898A1 (en) * | 2001-12-21 | 2003-07-09 | Universite Libre De Bruxelles | Method for obtaining the elimination of integrated and functional viruses from infected mammal cells |
| US8247613B2 (en) * | 2006-04-17 | 2012-08-21 | The J. David Gladstone Institutes | Methods and compositions for the synergistic activation of latent HIV |
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2009
- 2009-10-29 PL PL09759664T patent/PL2349245T3/pl unknown
- 2009-10-29 JP JP2011533630A patent/JP5779503B2/ja active Active
- 2009-10-29 US US13/125,325 patent/US8785493B2/en active Active
- 2009-10-29 WO PCT/EP2009/007958 patent/WO2010049182A2/en not_active Ceased
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2014
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2016
- 2016-12-21 US US15/386,336 patent/US20170157174A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012506884A (ja) | 2012-03-22 |
| PL2349245T3 (pl) | 2017-07-31 |
| JP5779503B2 (ja) | 2015-09-16 |
| US8785493B2 (en) | 2014-07-22 |
| US20150024065A1 (en) | 2015-01-22 |
| US20110305774A1 (en) | 2011-12-15 |
| WO2010049182A2 (en) | 2010-05-06 |
| US20170157174A1 (en) | 2017-06-08 |
| EP2349245B1 (en) | 2016-08-03 |
| WO2010049182A3 (en) | 2010-12-02 |
| EP2349245A2 (en) | 2011-08-03 |
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