ES2586410T3 - Procedimientos y composiciones de detección de un mutante de EGFR resistente a fármacos - Google Patents

Procedimientos y composiciones de detección de un mutante de EGFR resistente a fármacos Download PDF

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Publication number
ES2586410T3
ES2586410T3 ES06720702.7T ES06720702T ES2586410T3 ES 2586410 T3 ES2586410 T3 ES 2586410T3 ES 06720702 T ES06720702 T ES 06720702T ES 2586410 T3 ES2586410 T3 ES 2586410T3
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ES
Spain
Prior art keywords
sequence
patient
gefitinib
egfr
erlotinib
Prior art date
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Expired - Lifetime
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ES06720702.7T
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English (en)
Spanish (es)
Inventor
Harold Varmus
Katerina Politi
William Pao
Vincent Miller
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Memorial Sloan Kettering Cancer Center
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Memorial Sloan Kettering Cancer Center
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36793833&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2586410(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Memorial Sloan Kettering Cancer Center filed Critical Memorial Sloan Kettering Cancer Center
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Publication of ES2586410T3 publication Critical patent/ES2586410T3/es
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES06720702.7T 2005-02-11 2006-02-13 Procedimientos y composiciones de detección de un mutante de EGFR resistente a fármacos Expired - Lifetime ES2586410T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65248805P 2005-02-11 2005-02-11
US652488P 2005-02-11
PCT/US2006/005050 WO2006086777A2 (en) 2005-02-11 2006-02-13 Methods and compositions for detecting a drug resistant egfr mutant

Publications (1)

Publication Number Publication Date
ES2586410T3 true ES2586410T3 (es) 2016-10-14

Family

ID=36793833

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06720702.7T Expired - Lifetime ES2586410T3 (es) 2005-02-11 2006-02-13 Procedimientos y composiciones de detección de un mutante de EGFR resistente a fármacos

Country Status (7)

Country Link
US (2) US8067175B2 (https=)
EP (2) EP1851339B1 (https=)
JP (2) JP4898710B2 (https=)
CN (1) CN101193905B (https=)
CA (1) CA2597673C (https=)
ES (1) ES2586410T3 (https=)
WO (1) WO2006086777A2 (https=)

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Also Published As

Publication number Publication date
CN101193905B (zh) 2014-06-25
CA2597673C (en) 2014-07-08
CN101193905A (zh) 2008-06-04
CA2597673A1 (en) 2006-08-17
EP1851339A4 (en) 2009-05-27
WO2006086777A3 (en) 2007-11-22
US8501413B2 (en) 2013-08-06
WO2006086777A2 (en) 2006-08-17
JP2008529532A (ja) 2008-08-07
EP1851339B1 (en) 2016-05-18
HK1118832A1 (en) 2009-02-20
US20120077201A1 (en) 2012-03-29
JP2012070746A (ja) 2012-04-12
US8067175B2 (en) 2011-11-29
EP1851339A2 (en) 2007-11-07
US20100173285A1 (en) 2010-07-08
JP4898710B2 (ja) 2012-03-21
EP2505591A1 (en) 2012-10-03

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