ES2585239T3 - Nuevos agonistas sintéticos de TLR9 - Google Patents

Nuevos agonistas sintéticos de TLR9 Download PDF

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Publication number
ES2585239T3
ES2585239T3 ES14183548.8T ES14183548T ES2585239T3 ES 2585239 T3 ES2585239 T3 ES 2585239T3 ES 14183548 T ES14183548 T ES 14183548T ES 2585239 T3 ES2585239 T3 ES 2585239T3
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Spain
Prior art keywords
compound
disease
disorder
tlr9
immune response
Prior art date
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ES14183548.8T
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English (en)
Spanish (es)
Inventor
Ekambar R. Kandimalla
Mallikarjuna Reddy Putta
Daqing Wang
Dong Yu
Lakshmi Bhagat
Sudhir Agrawal
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Aceragen Inc
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Idera Pharmaceuticals Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/06—Antiasthmatics
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    • A61P13/10—Drugs for disorders of the urinary system of the bladder
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
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    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

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  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
ES14183548.8T 2007-08-01 2008-07-31 Nuevos agonistas sintéticos de TLR9 Active ES2585239T3 (es)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US15292P 1996-04-11
US95325107P 2007-08-01 2007-08-01
US953251P 2007-08-01
US98360107P 2007-10-30 2007-10-30
US983601P 2007-10-30
US98715107P 2007-11-12 2007-11-12
US987151P 2007-11-12
US1529207P 2007-12-20 2007-12-20

Publications (1)

Publication Number Publication Date
ES2585239T3 true ES2585239T3 (es) 2016-10-04

Family

ID=40305273

Family Applications (2)

Application Number Title Priority Date Filing Date
ES14183548.8T Active ES2585239T3 (es) 2007-08-01 2008-07-31 Nuevos agonistas sintéticos de TLR9
ES13171674.8T Active ES2539353T3 (es) 2007-08-01 2008-07-31 Nuevos agonistas sintéticos de TLR9

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES13171674.8T Active ES2539353T3 (es) 2007-08-01 2008-07-31 Nuevos agonistas sintéticos de TLR9

Country Status (12)

Country Link
US (2) US7960362B2 (cg-RX-API-DMAC10.html)
EP (3) EP2650369B1 (cg-RX-API-DMAC10.html)
JP (2) JP5563455B2 (cg-RX-API-DMAC10.html)
KR (1) KR20100053598A (cg-RX-API-DMAC10.html)
CN (3) CN102864151B (cg-RX-API-DMAC10.html)
AU (1) AU2008282172B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0813981A2 (cg-RX-API-DMAC10.html)
CA (1) CA2693266C (cg-RX-API-DMAC10.html)
ES (2) ES2585239T3 (cg-RX-API-DMAC10.html)
IN (1) IN2010KN00195A (cg-RX-API-DMAC10.html)
RU (1) RU2468819C2 (cg-RX-API-DMAC10.html)
WO (1) WO2009018431A2 (cg-RX-API-DMAC10.html)

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CN102864151A (zh) 2013-01-09
AU2008282172B2 (en) 2014-05-22
CA2693266A1 (en) 2009-02-05
EP2650369B1 (en) 2015-04-29
US7960362B2 (en) 2011-06-14
CN105177014B (zh) 2018-04-06
US20090053206A1 (en) 2009-02-26
CN102864151B (zh) 2015-07-08
EP2173912A2 (en) 2010-04-14
JP2014205691A (ja) 2014-10-30
EP2821488A3 (en) 2015-04-29
JP2010535242A (ja) 2010-11-18
WO2009018431A3 (en) 2009-12-30
AU2008282172A1 (en) 2009-02-05
WO2009018431A2 (en) 2009-02-05
JP5816720B2 (ja) 2015-11-18
KR20100053598A (ko) 2010-05-20
IN2010KN00195A (cg-RX-API-DMAC10.html) 2015-08-28
CN101878311A (zh) 2010-11-03
RU2468819C2 (ru) 2012-12-10
US20110311518A1 (en) 2011-12-22
HK1216430A1 (zh) 2016-11-11
ES2539353T3 (es) 2015-06-30
CA2693266C (en) 2015-06-30
RU2010107207A (ru) 2011-09-10
JP5563455B2 (ja) 2014-07-30
EP2650369A1 (en) 2013-10-16
EP2821488A2 (en) 2015-01-07
BRPI0813981A2 (pt) 2017-05-09
CN105177014A (zh) 2015-12-23
EP2173912A4 (en) 2013-03-20
US8361986B2 (en) 2013-01-29
EP2821488B1 (en) 2016-07-27

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