ES2584956T3 - Anticuerpos anti-CD40 y usos de los mismos - Google Patents

Anticuerpos anti-CD40 y usos de los mismos Download PDF

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Publication number
ES2584956T3
ES2584956T3 ES10751218.8T ES10751218T ES2584956T3 ES 2584956 T3 ES2584956 T3 ES 2584956T3 ES 10751218 T ES10751218 T ES 10751218T ES 2584956 T3 ES2584956 T3 ES 2584956T3
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antibody
seq
sequence identity
heavy chain
light chain
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Jacques F. Banchereau
Gerard Zurawski
Sandra Zurawski
Sangkon Oh
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Baylor Research Institute
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Baylor Research Institute
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
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    • A61K2039/6056—Antibodies
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract

Un anticuerpo recombinante humanizado o un fragmento de unión a antígeno del mismo que se une a CD40, que comprende al menos un dominio variable que tiene una identidad de secuencias de un 90 % con al menos una región variable de cadena ligera de anticuerpo de SEQ ID NO: 7; y al menos un dominio variable que tiene una identidad de secuencias de un 90 % con una región variable de cadena pesada de anticuerpo de SEQ ID NO: 6 y en el que el anticuerpo tiene las CDR obtenidas a partir del anticuerpo anti-CD40_11B6.1C3 que tiene una cadena pesada de SEQ ID NO: 6 y una cadena ligera de SEQ ID NO: 7.
ES10751218.8T 2009-03-10 2010-03-05 Anticuerpos anti-CD40 y usos de los mismos Active ES2584956T3 (es)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US718365 1985-04-01
US15906209P 2009-03-10 2009-03-10
US15905909P 2009-03-10 2009-03-10
US15905509P 2009-03-10 2009-03-10
US159062P 2009-03-10
US159055P 2009-03-10
US159059P 2009-03-10
PCT/US2010/026375 WO2010104761A2 (en) 2009-03-10 2010-03-05 Anti-cd40 antibodies and uses thereof
US12/718,365 US9562104B2 (en) 2009-03-10 2010-03-05 Anti-CD40 antibodies

Publications (1)

Publication Number Publication Date
ES2584956T3 true ES2584956T3 (es) 2016-09-30

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ES10751218.8T Active ES2584956T3 (es) 2009-03-10 2010-03-05 Anticuerpos anti-CD40 y usos de los mismos

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US (6) US9562104B2 (es)
EP (1) EP2406286B1 (es)
JP (3) JP5653945B2 (es)
CN (2) CN102448989B (es)
AR (1) AR076106A1 (es)
AU (1) AU2010222942B2 (es)
BR (1) BRPI1009455A2 (es)
CA (2) CA2754862C (es)
DK (1) DK2406286T3 (es)
ES (1) ES2584956T3 (es)
MX (1) MX2011009438A (es)
PT (1) PT2406286T (es)
TW (1) TWI571264B (es)
WO (1) WO2010104761A2 (es)

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US9562104B2 (en) 2009-03-10 2017-02-07 Baylor Research Institute Anti-CD40 antibodies
GB201006096D0 (en) * 2010-04-13 2010-05-26 Alligator Bioscience Ab Novel compositions and uses thereof
US9586996B2 (en) * 2010-04-30 2017-03-07 Esperance Pharmaceuticals, Inc. Lytic-peptide-Her2/neu (human epidermal growth factor receptor 2) ligand conjugates and methods of use
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TWI506035B (zh) * 2010-08-13 2015-11-01 Baylor Res Inst 以直接針對抗原呈現細胞之抗體的標靶佐劑為主之新穎疫苗佐劑
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EP3556774B1 (en) * 2011-03-11 2024-01-03 Beth Israel Deaconess Medical Center Inc. Anti-cd40 antibodies and uses thereof
EP2688592A4 (en) * 2011-03-25 2015-07-22 Baylor Res Inst Compositions and methods for immunization against the hepatitis C virus
WO2012149356A2 (en) 2011-04-29 2012-11-01 Apexigen, Inc. Anti-cd40 antibodies and methods of use
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CN104918957B (zh) 2012-10-30 2018-11-16 埃派斯进有限公司 抗-cd40抗体及其使用方法
JP6566941B2 (ja) 2013-06-28 2019-08-28 ベイラー リサーチ インスティテュートＢａｙｌｏｒ Ｒｅｓｅａｒｃｈ Ｉｎｓｔｉｔｕｔｅ 多発性硬化症のための樹状細胞ａｓｇｐｒ標的化免疫治療薬
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