ES2580135T3 - Métodos de tratamiento de carcinoma hepatocelular - Google Patents

Métodos de tratamiento de carcinoma hepatocelular Download PDF

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Publication number
ES2580135T3
ES2580135T3 ES11760333.2T ES11760333T ES2580135T3 ES 2580135 T3 ES2580135 T3 ES 2580135T3 ES 11760333 T ES11760333 T ES 11760333T ES 2580135 T3 ES2580135 T3 ES 2580135T3
Authority
ES
Spain
Prior art keywords
composition
nanoparticles
albumin
taxane
paclitaxel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11760333.2T
Other languages
English (en)
Spanish (es)
Inventor
Winnie Yeo
Nathalie Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abraxis Bioscience LLC
Original Assignee
Abraxis Bioscience LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abraxis Bioscience LLC filed Critical Abraxis Bioscience LLC
Application granted granted Critical
Publication of ES2580135T3 publication Critical patent/ES2580135T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
ES11760333.2T 2010-03-26 2011-03-25 Métodos de tratamiento de carcinoma hepatocelular Active ES2580135T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31815310P 2010-03-26 2010-03-26
US318153P 2010-03-26
PCT/US2011/030037 WO2011119988A1 (en) 2010-03-26 2011-03-25 Methods of treatment of hepatocellular carcinoma

Publications (1)

Publication Number Publication Date
ES2580135T3 true ES2580135T3 (es) 2016-08-19

Family

ID=44673662

Family Applications (2)

Application Number Title Priority Date Filing Date
ES11760333.2T Active ES2580135T3 (es) 2010-03-26 2011-03-25 Métodos de tratamiento de carcinoma hepatocelular
ES14200645.1T Active ES2675212T3 (es) 2010-03-26 2011-03-25 Métodos de tratamiento de carcinoma hepatocelular

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES14200645.1T Active ES2675212T3 (es) 2010-03-26 2011-03-25 Métodos de tratamiento de carcinoma hepatocelular

Country Status (20)

Country Link
US (3) US9370494B2 (enExample)
EP (2) EP2898884B1 (enExample)
JP (2) JP5847156B2 (enExample)
KR (1) KR101786142B1 (enExample)
CN (2) CN103052385B (enExample)
AU (1) AU2011230512B2 (enExample)
BR (1) BR112012024349A2 (enExample)
CA (2) CA2793536C (enExample)
DK (1) DK2552438T3 (enExample)
ES (2) ES2580135T3 (enExample)
HR (1) HRP20160609T1 (enExample)
HU (1) HUE027749T2 (enExample)
IL (2) IL221886A (enExample)
LT (1) LT2552438T (enExample)
MX (2) MX359413B (enExample)
NZ (1) NZ602382A (enExample)
PL (1) PL2552438T3 (enExample)
PT (1) PT2552438T (enExample)
TW (1) TWI495467B (enExample)
WO (1) WO2011119988A1 (enExample)

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Also Published As

Publication number Publication date
CN103052385B (zh) 2015-05-27
IL221886A (en) 2016-08-31
WO2011119988A1 (en) 2011-09-29
CN104784121A (zh) 2015-07-22
LT2552438T (lt) 2016-09-26
CA2793536A1 (en) 2011-09-29
MX346861B (es) 2017-04-04
PL2552438T3 (pl) 2016-12-30
MX359413B (es) 2018-09-27
BR112012024349A2 (pt) 2016-05-24
HK1212926A1 (en) 2016-06-24
MX2012010936A (es) 2012-10-10
TWI495467B (zh) 2015-08-11
JP2015134825A (ja) 2015-07-27
DK2552438T3 (en) 2016-07-04
KR101786142B1 (ko) 2017-10-17
EP2552438A4 (en) 2013-09-04
US20160374952A1 (en) 2016-12-29
ES2675212T3 (es) 2018-07-09
HUE027749T2 (en) 2016-10-28
EP2552438B1 (en) 2016-05-11
AU2011230512B2 (en) 2016-09-15
PT2552438T (pt) 2016-07-07
TW201138765A (en) 2011-11-16
US20130115296A1 (en) 2013-05-09
US9370494B2 (en) 2016-06-21
AU2011230512A1 (en) 2012-10-04
HK1181665A1 (zh) 2013-11-15
CA2793536C (en) 2019-10-01
HRP20160609T1 (hr) 2016-09-23
EP2898884A1 (en) 2015-07-29
JP2013523656A (ja) 2013-06-17
CA3051495A1 (en) 2011-09-29
JP5847156B2 (ja) 2016-01-20
IL247171B (en) 2019-02-28
EP2898884B1 (en) 2018-05-09
US20140079787A1 (en) 2014-03-20
KR20130062922A (ko) 2013-06-13
NZ602382A (en) 2014-11-28
EP2552438A1 (en) 2013-02-06
CN103052385A (zh) 2013-04-17

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