LT2552438T - Hepatoceliulinės karcinomos gydymo būdai - Google Patents

Hepatoceliulinės karcinomos gydymo būdai

Info

Publication number
LT2552438T
LT2552438T LTEP11760333.2T LT11760333T LT2552438T LT 2552438 T LT2552438 T LT 2552438T LT 11760333 T LT11760333 T LT 11760333T LT 2552438 T LT2552438 T LT 2552438T
Authority
LT
Lithuania
Prior art keywords
treatment
methods
hepatocellular carcinoma
hepatocellular
carcinoma
Prior art date
Application number
LTEP11760333.2T
Other languages
English (en)
Lithuanian (lt)
Inventor
Winnie Yeo
Nathalie Wong
Original Assignee
Abraxis Bioscience, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abraxis Bioscience, Llc filed Critical Abraxis Bioscience, Llc
Publication of LT2552438T publication Critical patent/LT2552438T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
LTEP11760333.2T 2010-03-26 2011-03-25 Hepatoceliulinės karcinomos gydymo būdai LT2552438T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31815310P 2010-03-26 2010-03-26
PCT/US2011/030037 WO2011119988A1 (en) 2010-03-26 2011-03-25 Methods of treatment of hepatocellular carcinoma

Publications (1)

Publication Number Publication Date
LT2552438T true LT2552438T (lt) 2016-09-26

Family

ID=44673662

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP11760333.2T LT2552438T (lt) 2010-03-26 2011-03-25 Hepatoceliulinės karcinomos gydymo būdai

Country Status (20)

Country Link
US (3) US9370494B2 (enExample)
EP (2) EP2898884B1 (enExample)
JP (2) JP5847156B2 (enExample)
KR (1) KR101786142B1 (enExample)
CN (2) CN104784121A (enExample)
AU (1) AU2011230512B2 (enExample)
BR (1) BR112012024349A2 (enExample)
CA (2) CA2793536C (enExample)
DK (1) DK2552438T3 (enExample)
ES (2) ES2675212T3 (enExample)
HR (1) HRP20160609T1 (enExample)
HU (1) HUE027749T2 (enExample)
IL (2) IL221886A (enExample)
LT (1) LT2552438T (enExample)
MX (2) MX359413B (enExample)
NZ (1) NZ602382A (enExample)
PL (1) PL2552438T3 (enExample)
PT (1) PT2552438T (enExample)
TW (1) TWI495467B (enExample)
WO (1) WO2011119988A1 (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
HUE040046T2 (hu) 2002-12-09 2019-02-28 Abraxis Bioscience Llc Gyógyszerészeti készítmények és hatóanyagok beadására szolgáló eljárások
EP1853250B1 (en) 2005-02-18 2011-11-02 Abraxis BioScience, LLC Combinations and modes of administration of therapeutic agents and combination therapy
US8735394B2 (en) 2005-02-18 2014-05-27 Abraxis Bioscience, Llc Combinations and modes of administration of therapeutic agents and combination therapy
TR200801337T1 (tr) * 2005-08-31 2008-07-21 Abraxis Bioscience, Llc. Suda zayıf çözülebilen farmasötik ajanlar ve antimikrobiyal ajanlar içeren kompozisyonlar.
PL2117520T3 (pl) * 2006-12-14 2019-03-29 Abraxis Bioscience, Llc Terapia raka piersi w oparciu o status występowania receptora hormonalnego przy użyciu nanocząstek zawierających taksan
PT2131821T (pt) * 2007-03-07 2018-10-10 Abraxis Bioscience Llc Nanopartícula que compreende rapamicina e albumina como agente anticancerígeno
JP5579057B2 (ja) * 2007-06-01 2014-08-27 アブラクシス バイオサイエンス, エルエルシー 再発性癌の処置のための方法および組成物
CA2758913A1 (en) 2009-04-15 2010-10-21 Abraxis Bioscience, Llc Prion free nanoparticle compositions and methods of making thereof
BR112012024349A2 (pt) 2010-03-26 2016-05-24 Abraxis Bioscience Llc métodos de tratamento de carcinoma hepatocelular
ES2600912T3 (es) 2010-03-29 2017-02-13 Abraxis Bioscience, Llc Métodos para tratar el cáncer
KR20190109593A (ko) 2010-03-29 2019-09-25 아브락시스 바이오사이언스, 엘엘씨 치료제의 약물 전달 및 유효성 향상 방법
KR20180049180A (ko) 2010-06-04 2018-05-10 아브락시스 바이오사이언스, 엘엘씨 췌장암의 치료 방법
JP6038123B2 (ja) 2011-04-28 2016-12-07 アブラクシス バイオサイエンス, エルエルシー ナノ粒子組成物の脈管内送達およびそれらの使用
HUE045661T2 (hu) 2011-12-14 2020-01-28 Abraxis Bioscience Llc Polimer segédanyagok alkalmazása részecskék liofilizálásához vagy fagyasztásához
US9149455B2 (en) 2012-11-09 2015-10-06 Abraxis Bioscience, Llc Methods of treating melanoma
US20140186447A1 (en) * 2012-12-28 2014-07-03 Abraxis Bioscience, Llc Nanoparticle compositions of albumin and paclitaxel
US9511046B2 (en) 2013-01-11 2016-12-06 Abraxis Bioscience, Llc Methods of treating pancreatic cancer
CN105228612A (zh) 2013-03-12 2016-01-06 阿布拉科斯生物科学有限公司 治疗肺癌的方法
US9962373B2 (en) 2013-03-14 2018-05-08 Abraxis Bioscience, Llc Methods of treating bladder cancer
MA38687A1 (fr) 2013-05-30 2017-12-29 Nanobiotix Composition pharmaceutique, préparation et utilisations de celle-ci
WO2015120273A1 (en) * 2014-02-07 2015-08-13 The General Hospital Corporation Differential diagnosis of hepatic neoplasms
ES2951598T3 (es) 2014-11-25 2023-10-23 Curadigm Sas Composición farmacéutica que combina al menos dos nanopartículas distintas y un compuesto farmacéutico, preparación y usos de los mismos
EP3229843B1 (en) * 2014-11-25 2020-01-01 Curadigm Sas Pharmaceutical composition, preparation and uses thereof
TW201628656A (zh) 2014-11-25 2016-08-16 奈諾生技公司 醫藥組合物、其製備與用途
US11304902B2 (en) 2014-11-25 2022-04-19 Curadigm Sas Pharmaceutical compositions, preparation and uses thereof
US10705070B1 (en) 2015-03-05 2020-07-07 Abraxis Bioscience, Llc Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug
US10527604B1 (en) 2015-03-05 2020-01-07 Abraxis Bioscience, Llc Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel
MA43100A (fr) 2015-05-28 2018-09-05 Nanobiotix Nanoparticules à utiliser en tant que vaccin thérapeutique
CN116473964A (zh) 2015-06-29 2023-07-25 阿布拉科斯生物科学有限公司 治疗上皮样细胞肿瘤的方法
BR112019006329A2 (pt) * 2016-10-07 2019-06-25 Abraxis Bioscience Llc métodos de tratamento de câncer do trato biliar
CN110062622B (zh) 2016-10-27 2022-10-14 珠海贝海生物技术有限公司 多西他赛和人血清白蛋白的中性pH组合物
US10896749B2 (en) * 2017-01-27 2021-01-19 Shire Human Genetic Therapies, Inc. Drug monitoring tool
CN107828887A (zh) * 2017-10-12 2018-03-23 上海市东方医院 Stmn1基因的用途
MX2020009740A (es) 2018-03-20 2021-01-20 Abraxis Bioscience Llc Metodos para el tratamiento de trastornos del sistema nervioso central mediante la administracion de nanoparticulas de un inhibidor del objetivo de la rapamicina en mamiferos (mtor) y una albumina.
AU2020375810A1 (en) 2019-10-28 2022-05-12 Abraxis Bioscience, Llc Pharmaceutical compositions of albumin and rapamycin
JP2024542042A (ja) * 2021-10-26 2024-11-13 リポジェムス・インターナショナル・エッセ・ピ・ア 肝がん療法での薬物送達システムとしての微小断片化脂肪組織

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362478A (en) 1993-03-26 1994-11-08 Vivorx Pharmaceuticals, Inc. Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell
US5997904A (en) 1993-02-22 1999-12-07 American Bioscience, Inc. Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof
US6528067B1 (en) 1993-02-22 2003-03-04 American Bioscience, Inc. Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof
US6749868B1 (en) 1993-02-22 2004-06-15 American Bioscience, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
US6537579B1 (en) 1993-02-22 2003-03-25 American Bioscience, Inc. Compositions and methods for administration of pharmacologically active compounds
US6753006B1 (en) 1993-02-22 2004-06-22 American Bioscience, Inc. Paclitaxel-containing formulations
US5650156A (en) 1993-02-22 1997-07-22 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of nutriceuticals and compositions useful therefor
US5665382A (en) 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of pharmaceutically active agents for in vivo delivery
US6096331A (en) 1993-02-22 2000-08-01 Vivorx Pharmaceuticals, Inc. Methods and compositions useful for administration of chemotherapeutic agents
US5665383A (en) 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of immunostimulating agents for in vivo delivery
WO1999000113A1 (en) 1997-06-27 1999-01-07 Vivorx Pharmaceuticals, Inc. Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
US5916596A (en) 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
CN1245156C (zh) 1993-02-22 2006-03-15 美国生物科学有限公司 用于体内传送生物制品的方法及用于该方法的组合物
US5439686A (en) 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US20030068362A1 (en) 1993-02-22 2003-04-10 American Bioscience, Inc. Methods and formulations for the delivery of pharmacologically active agents
US6565842B1 (en) 1995-06-07 2003-05-20 American Bioscience, Inc. Crosslinkable polypeptide compositions
US8137684B2 (en) 1996-10-01 2012-03-20 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
US20030199425A1 (en) 1997-06-27 2003-10-23 Desai Neil P. Compositions and methods for treatment of hyperplasia
CA2369740A1 (en) 1999-04-22 2000-11-02 American Biosciences, Inc. Long term administration of pharmacologically active agents
CA2371912C (en) 1999-05-21 2010-02-16 American Bioscience, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
GB9920548D0 (en) 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
ITMI20001107A1 (it) 2000-05-18 2001-11-18 Acs Dobfar Spa Metodo per il trattamento di tumori solici mediante microparticelle di albumina incorporanti paclitaxel
ITMI20020680A1 (it) 2002-03-29 2003-09-29 Acs Dobfar Spa Composizione antitumorale migliorata a base di paclitaxel e metodo per il suo ottenimento
ITMI20020681A1 (it) 2002-03-29 2003-09-29 Acs Dobfar Spa Procedimento per la produzione di nanoparticelle di paclitaxel ed albumina
HUE040046T2 (hu) 2002-12-09 2019-02-28 Abraxis Bioscience Llc Gyógyszerészeti készítmények és hatóanyagok beadására szolgáló eljárások
KR20140027554A (ko) 2002-12-09 2014-03-06 아브락시스 바이오사이언스, 엘엘씨 약리학적 물질의 조성물 및 그 전달방법
US8735394B2 (en) 2005-02-18 2014-05-27 Abraxis Bioscience, Llc Combinations and modes of administration of therapeutic agents and combination therapy
US20070166388A1 (en) 2005-02-18 2007-07-19 Desai Neil P Combinations and modes of administration of therapeutic agents and combination therapy
EP1853250B1 (en) 2005-02-18 2011-11-02 Abraxis BioScience, LLC Combinations and modes of administration of therapeutic agents and combination therapy
TR200801337T1 (tr) 2005-08-31 2008-07-21 Abraxis Bioscience, Llc. Suda zayıf çözülebilen farmasötik ajanlar ve antimikrobiyal ajanlar içeren kompozisyonlar.
JP5368093B2 (ja) 2005-08-31 2013-12-18 アブラクシス バイオサイエンス, エルエルシー 増大した安定性を有する難水溶性薬剤の組成物および調製の方法
US20080045589A1 (en) * 2006-05-26 2008-02-21 Susan Kelley Drug Combinations with Substituted Diaryl Ureas for the Treatment of Cancer
US20080280987A1 (en) 2006-08-31 2008-11-13 Desai Neil P Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases
JP2010502603A (ja) 2006-08-31 2010-01-28 アブラクシス バイオサイエンス, エルエルシー 血管形成を阻害し、血管形成関連疾患を処置する方法
CA2663878A1 (en) * 2006-09-19 2008-03-27 Asuragen, Inc. Mir-200 regulated genes and pathways as targets for therapeutic intervention
PL2117520T3 (pl) 2006-12-14 2019-03-29 Abraxis Bioscience, Llc Terapia raka piersi w oparciu o status występowania receptora hormonalnego przy użyciu nanocząstek zawierających taksan
PT2131821T (pt) 2007-03-07 2018-10-10 Abraxis Bioscience Llc Nanopartícula que compreende rapamicina e albumina como agente anticancerígeno
JP5641927B2 (ja) 2007-04-13 2014-12-17 アブラクシス バイオサイエンス リミテッド ライアビリティー カンパニー Sparc及びその使用方法
WO2008137148A2 (en) 2007-05-03 2008-11-13 Abraxis Bioscience, Llc Methods and compositions for treating pulmonary hypertension
JP5579057B2 (ja) 2007-06-01 2014-08-27 アブラクシス バイオサイエンス, エルエルシー 再発性癌の処置のための方法および組成物
AU2009234127B2 (en) 2008-04-10 2015-04-30 Abraxis Bioscience, Llc Compositions of hydrophobic taxane derivatives and uses thereof
JP2011517683A (ja) 2008-04-10 2011-06-16 アブラクシス バイオサイエンス, エルエルシー 疎水性タキサン誘導体の組成物およびその使用
US20120128732A1 (en) 2008-12-11 2012-05-24 Vuong Trieu Combinations and modes of administration of therapeutic agents and combination therapy
KR101739598B1 (ko) 2009-03-13 2017-06-08 아브락시스 바이오사이언스, 엘엘씨 티오콜키신 유도체와의 조합 요법
EP2416650B1 (en) 2009-04-10 2020-02-26 Abraxis BioScience, LLC Nanoparticle formulations and uses therof
CA2758913A1 (en) 2009-04-15 2010-10-21 Abraxis Bioscience, Llc Prion free nanoparticle compositions and methods of making thereof
AU2010286670B2 (en) 2009-08-25 2016-04-21 Abraxis Bioscience, Llc Combination therapy with nanoparticle compositions of taxane and hedgehog inhibitors
BR112012024349A2 (pt) 2010-03-26 2016-05-24 Abraxis Bioscience Llc métodos de tratamento de carcinoma hepatocelular
ES2600912T3 (es) 2010-03-29 2017-02-13 Abraxis Bioscience, Llc Métodos para tratar el cáncer
KR20190109593A (ko) 2010-03-29 2019-09-25 아브락시스 바이오사이언스, 엘엘씨 치료제의 약물 전달 및 유효성 향상 방법
MX343671B (es) 2010-06-02 2016-11-16 Abraxis Bioscience Llc * Metodos de tratamiento de cancer de vejiga.
KR20180049180A (ko) 2010-06-04 2018-05-10 아브락시스 바이오사이언스, 엘엘씨 췌장암의 치료 방법
MX2012014231A (es) 2010-06-07 2013-01-28 Abraxis Bioscience Llc Metodos de terapia combinada para tratar enfermedades proliferativas.
JP6038123B2 (ja) 2011-04-28 2016-12-07 アブラクシス バイオサイエンス, エルエルシー ナノ粒子組成物の脈管内送達およびそれらの使用
HUE045661T2 (hu) 2011-12-14 2020-01-28 Abraxis Bioscience Llc Polimer segédanyagok alkalmazása részecskék liofilizálásához vagy fagyasztásához
US9149455B2 (en) 2012-11-09 2015-10-06 Abraxis Bioscience, Llc Methods of treating melanoma
US20140186447A1 (en) 2012-12-28 2014-07-03 Abraxis Bioscience, Llc Nanoparticle compositions of albumin and paclitaxel
US9511046B2 (en) 2013-01-11 2016-12-06 Abraxis Bioscience, Llc Methods of treating pancreatic cancer
US20140199405A1 (en) 2013-01-11 2014-07-17 Abraxis Bioscience, Llc Method for treating cancer based on mutation status of k-ras
US20140199404A1 (en) 2013-01-11 2014-07-17 Abraxis Bioscience, Llc Method for treating cancer based on level of a nucleoside transporter

Also Published As

Publication number Publication date
MX359413B (es) 2018-09-27
CN103052385B (zh) 2015-05-27
CN104784121A (zh) 2015-07-22
EP2552438A4 (en) 2013-09-04
HK1181665A1 (zh) 2013-11-15
JP5847156B2 (ja) 2016-01-20
EP2898884B1 (en) 2018-05-09
CN103052385A (zh) 2013-04-17
CA3051495A1 (en) 2011-09-29
JP2015134825A (ja) 2015-07-27
US20140079787A1 (en) 2014-03-20
BR112012024349A2 (pt) 2016-05-24
ES2580135T3 (es) 2016-08-19
PT2552438T (pt) 2016-07-07
AU2011230512B2 (en) 2016-09-15
CA2793536C (en) 2019-10-01
US20160374952A1 (en) 2016-12-29
EP2552438B1 (en) 2016-05-11
MX2012010936A (es) 2012-10-10
EP2898884A1 (en) 2015-07-29
HK1212926A1 (en) 2016-06-24
DK2552438T3 (en) 2016-07-04
JP2013523656A (ja) 2013-06-17
WO2011119988A1 (en) 2011-09-29
IL221886A (en) 2016-08-31
TW201138765A (en) 2011-11-16
HUE027749T2 (en) 2016-10-28
TWI495467B (zh) 2015-08-11
ES2675212T3 (es) 2018-07-09
CA2793536A1 (en) 2011-09-29
US20130115296A1 (en) 2013-05-09
US9370494B2 (en) 2016-06-21
KR101786142B1 (ko) 2017-10-17
EP2552438A1 (en) 2013-02-06
NZ602382A (en) 2014-11-28
AU2011230512A1 (en) 2012-10-04
KR20130062922A (ko) 2013-06-13
MX346861B (es) 2017-04-04
IL247171B (en) 2019-02-28
HRP20160609T1 (hr) 2016-09-23
PL2552438T3 (pl) 2016-12-30

Similar Documents

Publication Publication Date Title
LT2552438T (lt) Hepatoceliulinės karcinomos gydymo būdai
ZA201304280B (en) Treatment of jak2-mediated conditions
EP2717855A4 (en) PROCESSING METHODS
IL232530A0 (en) Combined cancer treatment
SI3124610T1 (sl) Zdravljenje HBV
SG10201508495VA (en) Combination treatment of cancer
SG2014014724A (en) METHODS FOR THE TREATMENT OF IL-1ß RELATED CONDITIONS
GB201018147D0 (en) Method of treatment
IL228430A0 (en) Cancer treatment
IL256026B (en) Treatment methods
GB201003920D0 (en) Method of treatment
ZA201102173B (en) Treatment of water
GB201018149D0 (en) Method of treatment
EP2585103A4 (en) METHOD OF TREATMENT
GB201020015D0 (en) Method of treatment
GB201014736D0 (en) Treatment of hepatitis C
GB201002499D0 (en) Treatment of tumours
GB201000318D0 (en) Method of treatment
GB201005071D0 (en) Method of treatment
GB201003917D0 (en) Method of treatment
GB201017354D0 (en) Treatment of cancer
GB201114710D0 (en) Treatment of hepatitis c
GB201110602D0 (en) Methods of treatment
GB201109737D0 (en) Methods of treatment
GB201017356D0 (en) Combination treatment of cancer