ES2563246T3 - Polímeros reticulados y productos médicos derivados de polioxazolina nucleofílicamente activada - Google Patents

Polímeros reticulados y productos médicos derivados de polioxazolina nucleofílicamente activada Download PDF

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Publication number
ES2563246T3
ES2563246T3 ES13712382.4T ES13712382T ES2563246T3 ES 2563246 T3 ES2563246 T3 ES 2563246T3 ES 13712382 T ES13712382 T ES 13712382T ES 2563246 T3 ES2563246 T3 ES 2563246T3
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groups
pox
electrophilic
crosslinking agent
polymer
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ES13712382.4T
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English (en)
Spanish (es)
Inventor
Johannes Caspar Mathias Elizabeth Bender
Richard Hoogenboom
Jan Cornelis Maria Van Hest
Harry Van Goor
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Bender Analytical Holding BV
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Bender Analytical Holding BV
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/48—Polymers modified by chemical after-treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0019—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0233—Polyamines derived from (poly)oxazolines, (poly)oxazines or having pendant acyl groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C08J3/246—Intercrosslinking of at least two polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L79/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen with or without oxygen or carbon only, not provided for in groups C08L61/00 - C08L77/00
    • C08L79/02—Polyamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2379/00—Characterised by the use of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen with or without oxygen, or carbon only, not provided for in groups C08J2361/00 - C08J2377/00
    • C08J2379/02—Polyamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2312/00—Crosslinking
ES13712382.4T 2012-03-16 2013-03-15 Polímeros reticulados y productos médicos derivados de polioxazolina nucleofílicamente activada Active ES2563246T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12159982 2012-03-16
EP12159982 2012-03-16
PCT/NL2013/050187 WO2013137736A1 (en) 2012-03-16 2013-03-15 Cross-linked polymers and medical products derived from nucleophilically activated polyoxazoline

Publications (1)

Publication Number Publication Date
ES2563246T3 true ES2563246T3 (es) 2016-03-11

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
ES13712382.4T Active ES2563246T3 (es) 2012-03-16 2013-03-15 Polímeros reticulados y productos médicos derivados de polioxazolina nucleofílicamente activada

Country Status (8)

Country Link
US (2) US9416228B2 (ja)
EP (1) EP2825582B1 (ja)
JP (2) JP6178399B2 (ja)
CN (1) CN104271638B (ja)
BR (1) BR112014022821B1 (ja)
ES (1) ES2563246T3 (ja)
HK (1) HK1206049A1 (ja)
WO (1) WO2013137736A1 (ja)

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JP6178399B2 (ja) * 2012-03-16 2017-08-09 ベンデル アナリティカル ホールディング ビー．ブイ．Ｂｅｎｄｅｒ Ａｎａｌｙｔｉｃａｌ Ｈｏｌｄｉｎｇ Ｂ．Ｖ． 求核的に活性化したポリオキサゾリンに由来する架橋ポリマー及び医療製品
DE102013016750A1 (de) * 2013-10-02 2015-04-02 Friedrich-Schiller-Universität Jena Neue Poly(ethylenimin) basierte Copolymere zur Anbindung und Freisetzung von genetischem Material, insbesondere von DNA/RNA, sowie Verfahren zu deren Herstellung und Verwendung
EP3000489B1 (en) * 2014-09-24 2017-04-05 Sofradim Production Method for preparing an anti-adhesion barrier film
US10232077B2 (en) 2014-10-06 2019-03-19 Gatt Technologies B.V. Tissue-adhesive porous haemostatic product
EP3943127A1 (en) * 2015-09-01 2022-01-26 Baxter International Inc Hemostatic material
CA2992692C (en) * 2015-09-09 2021-12-21 Eth Zurich Injectable macroporous hydrogels
KR102489614B1 (ko) * 2016-05-27 2023-01-16 삼성전자주식회사 옥사졸린계 공중합체, 이를 포함하는 조성물, 및 상기 조성물로부터 제조되는 성형품
CN106075549B (zh) * 2016-06-17 2020-02-14 广州迈普再生医学科技股份有限公司 组织封闭胶组合物，组织封闭胶及其制备方法和应用
KR101892955B1 (ko) * 2017-01-25 2018-08-29 국방과학연구소 치환된 Poly[2-(3-butenyl)-2-oxazoline] 및 Nylon-6,6를 포함하는 섬유 및 그 제조방법
US11571492B2 (en) * 2017-08-04 2023-02-07 Hcs Innovation, Llc Natural polymer-based tissue adhesive with healing-promoting properties
EP3681934A1 (en) * 2017-09-15 2020-07-22 Université de Strasbourg Injectable hybrid alginate hydrogels and uses thereof
CN109694484B (zh) * 2017-10-20 2021-08-27 四川大学华西医院 一种免疫佐剂及其制备方法
CN108939174B (zh) * 2018-07-16 2020-06-19 浙江大学 一种pH响应型聚噁唑啉-纳米银的层层自组装多层膜及其制备方法
CN109182260A (zh) * 2018-09-11 2019-01-11 邵勇 一种体外培养胎膜间充质干细胞的方法
CN109731133B (zh) * 2019-02-01 2020-09-01 浙江大学 一种抗菌、抗粘附、可注射式温敏壳聚糖凝胶敷料及其制备方法
CN109776808B (zh) * 2019-02-01 2020-06-30 浙江大学 一种水溶性改性壳聚糖的制备方法
AU2020312628A1 (en) * 2019-07-12 2022-01-20 Gatt Technologies B.V. Biocompatible, flexible, haemostatic sheet
WO2021009014A1 (en) * 2019-07-12 2021-01-21 Gatt Technologies B.V. Haemostatic powder
ES2962645T3 (es) * 2019-07-12 2024-03-20 Cilag Gmbh Int Lámina hemostática biocompatible y flexible
BR112022001554A2 (pt) * 2019-07-30 2022-03-22 Gatt Tech B V Copolímero de polioxazolina, uso do copolímero, produto médico biocompatível e processo de preparação de copolímeros
WO2021143736A1 (en) * 2020-01-16 2021-07-22 The Hong Kong University Of Science And Technology Compositions and methods for controlled release of target agent
CN111803454B (zh) * 2020-07-01 2022-05-06 中国科学院长春应用化学研究所 一种支架材料、其制备方法及应用
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ES2729787T3 (es) * 2011-01-04 2019-11-06 Gatt Tech B V Polímeros reticulados e implantes derivados de la polioxazolina activada de forma electrófila
JP6178399B2 (ja) * 2012-03-16 2017-08-09 ベンデル アナリティカル ホールディング ビー．ブイ．Ｂｅｎｄｅｒ Ａｎａｌｙｔｉｃａｌ Ｈｏｌｄｉｎｇ Ｂ．Ｖ． 求核的に活性化したポリオキサゾリンに由来する架橋ポリマー及び医療製品

Also Published As

Publication number Publication date
US9416228B2 (en) 2016-08-16
CN104271638A (zh) 2015-01-07
HK1206049A1 (zh) 2015-12-31
JP2015511507A (ja) 2015-04-20
WO2013137736A1 (en) 2013-09-19
JP6178399B2 (ja) 2017-08-09
BR112014022821A2 (ja) 2017-06-20
EP2825582B1 (en) 2016-01-13
JP6372000B2 (ja) 2018-08-15
US20150045507A1 (en) 2015-02-12
CN104271638B (zh) 2016-11-02
US20160319075A1 (en) 2016-11-03
JP2017221679A (ja) 2017-12-21
BR112014022821B1 (pt) 2021-03-30
EP2825582A1 (en) 2015-01-21
BR112014022821A8 (pt) 2018-07-31
US9868822B2 (en) 2018-01-16

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