ES255922A1 - Procedimiento para la preparaciën de la (cloro-2' amino-4' bencil)-1 bencil-4 piperacina - Google Patents
Procedimiento para la preparaciën de la (cloro-2' amino-4' bencil)-1 bencil-4 piperacinaInfo
- Publication number
- ES255922A1 ES255922A1 ES0255922A ES255922A ES255922A1 ES 255922 A1 ES255922 A1 ES 255922A1 ES 0255922 A ES0255922 A ES 0255922A ES 255922 A ES255922 A ES 255922A ES 255922 A1 ES255922 A1 ES 255922A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- group
- piperazine
- benzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004885 piperazines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 125000003277 amino group Chemical group 0.000 abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 2
- AFUCWUHGNVBJAO-UHFFFAOYSA-N (4-benzylpiperazin-1-yl)-(2-chloro-4-nitrophenyl)methanone Chemical compound ClC1=CC([N+](=O)[O-])=CC=C1C(=O)N1CCN(CC=2C=CC=CC=2)CC1 AFUCWUHGNVBJAO-UHFFFAOYSA-N 0.000 abstract 1
- IQXXEPZFOOTTBA-UHFFFAOYSA-N 1-benzylpiperazine Chemical compound C=1C=CC=CC=1CN1CCNCC1 IQXXEPZFOOTTBA-UHFFFAOYSA-N 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-M Methanesulfonate Chemical compound CS([O-])(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-M 0.000 abstract 1
- 229910002651 NO3 Inorganic materials 0.000 abstract 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- PASDCCFISLVPSO-UHFFFAOYSA-N benzoyl chloride Chemical class ClC(=O)C1=CC=CC=C1 PASDCCFISLVPSO-UHFFFAOYSA-N 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- AFAXGSQYZLGZPG-UHFFFAOYSA-N ethanedisulfonic acid Chemical compound OS(=O)(=O)CCS(O)(=O)=O AFAXGSQYZLGZPG-UHFFFAOYSA-N 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 229940095064 tartrate Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB6629/59A GB874096A (en) | 1959-02-25 | 1959-02-25 | New piperazine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES255922A1 true ES255922A1 (es) | 1960-07-01 |
Family
ID=9817938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0255922A Expired ES255922A1 (es) | 1959-02-25 | 1960-02-20 | Procedimiento para la preparaciën de la (cloro-2' amino-4' bencil)-1 bencil-4 piperacina |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE587892A (ja) |
| ES (1) | ES255922A1 (ja) |
| FR (3) | FR1292932A (ja) |
| GB (1) | GB874096A (ja) |
| NL (1) | NL105768C (ja) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY102447A (en) * | 1986-06-16 | 1992-06-30 | Ciba Geigy Ag | Disubtituted piperazines |
| EP0489690A1 (de) * | 1990-12-05 | 1992-06-10 | Ciba-Geigy Ag | Substituierte N-Benzoyl-N'-(2-phenylethyl)-piperazine |
| EP0524146A1 (de) * | 1991-07-19 | 1993-01-20 | Ciba-Geigy Ag | Aminosubstituierte Piperazinderivate |
| US5384319A (en) * | 1993-01-06 | 1995-01-24 | Ciba-Geigy Corporation | Aminoalkylphenyl compounds |
| US5380726A (en) * | 1993-01-15 | 1995-01-10 | Ciba-Geigy Corporation | Substituted dialkylthio ethers |
| EP0968200A1 (en) | 1997-02-24 | 2000-01-05 | ZymoGenetics, Inc. | Calcitonin mimetics |
| US6268367B1 (en) * | 1998-02-23 | 2001-07-31 | Zymogenetics, Inc. | Piperazine derivatives for treating bone deficit conditions |
| GB0719803D0 (en) | 2007-10-10 | 2007-11-21 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
-
0
- NL NL105768D patent/NL105768C/xx active
-
1959
- 1959-02-25 GB GB6629/59A patent/GB874096A/en not_active Expired
-
1960
- 1960-02-20 ES ES0255922A patent/ES255922A1/es not_active Expired
- 1960-02-22 BE BE587892A patent/BE587892A/fr unknown
- 1960-02-25 FR FR819592A patent/FR1292932A/fr not_active Expired
- 1960-04-01 FR FR823137A patent/FR1297718A/fr not_active Expired
- 1960-06-27 FR FR831247A patent/FR640M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| FR1292932A (fr) | 1962-05-11 |
| FR1297718A (fr) | 1962-07-06 |
| BE587892A (fr) | 1960-08-22 |
| GB874096A (en) | 1961-08-02 |
| FR640M (ja) | 1961-07-03 |
| NL105768C (ja) |
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