ES2554492T3 - Microvesículas (MVs) derivadas de citoblastos de etapa adulta para uso en el tratamiento terapéutico de una enfermedad neoplásica. - Google Patents
Microvesículas (MVs) derivadas de citoblastos de etapa adulta para uso en el tratamiento terapéutico de una enfermedad neoplásica. Download PDFInfo
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- ES2554492T3 ES2554492T3 ES11705585.5T ES11705585T ES2554492T3 ES 2554492 T3 ES2554492 T3 ES 2554492T3 ES 11705585 T ES11705585 T ES 11705585T ES 2554492 T3 ES2554492 T3 ES 2554492T3
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- cells
- mvs
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- derived
- cytoblast
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Immunology (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10425052A EP2363136A1 (en) | 2010-03-02 | 2010-03-02 | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
| EP10425052 | 2010-03-02 | ||
| PCT/EP2011/052945 WO2011107437A1 (en) | 2010-03-02 | 2011-02-28 | Microvesicles (mvs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2554492T3 true ES2554492T3 (es) | 2015-12-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11705585.5T Active ES2554492T3 (es) | 2010-03-02 | 2011-02-28 | Microvesículas (MVs) derivadas de citoblastos de etapa adulta para uso en el tratamiento terapéutico de una enfermedad neoplásica. |
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| Country | Link |
|---|---|
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| EP (2) | EP2363136A1 (cg-RX-API-DMAC7.html) |
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| EP2363136A1 (en) * | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
| CA2798900C (en) | 2010-05-12 | 2021-10-12 | Tengion, Inc. | Isolated secreted vesicles produced by bioactive renal cells |
| ITRM20110403A1 (it) * | 2011-07-28 | 2013-01-29 | Ospedale Pediatrico Bambino Gesu | Microvescicole isolate da cellule mesenchimali come agenti immunosoppressori. |
| CN102357071B (zh) * | 2011-10-26 | 2013-10-23 | 重庆医科大学附属儿童医院 | 载紫杉醇纳米微泡及其制备方法 |
| CN104136034B (zh) * | 2011-11-30 | 2018-04-24 | 安斯泰来再生医药协会 | 间充质基质细胞及其相关用途 |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| US11286463B2 (en) | 2012-03-08 | 2022-03-29 | Advanced ReGen Medical Technologies, LLC | Reprogramming of aged adult stem cells |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| US10772911B2 (en) | 2013-12-20 | 2020-09-15 | Advanced ReGen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
| US20150174166A1 (en) | 2013-12-20 | 2015-06-25 | Advanced ReGen Medical Technologies, LLC | Compositions for Cellular Restoration and Methods of Making and Using Same |
| EP4445915A3 (en) * | 2014-03-24 | 2025-01-22 | Advanced Regen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
| WO2015179301A1 (en) * | 2014-05-19 | 2015-11-26 | Eleftherios Papoutsakis | Megakaryocytic particles and microparticles for cell therapy & fate modification of stem and progenitor cells |
| WO2017190000A1 (en) | 2016-04-29 | 2017-11-02 | Advanced ReGen Medical Technologies, LLC | Microrna compositions and methods of making and using same |
| EP3724334A1 (en) * | 2017-12-14 | 2020-10-21 | Unicyte EV AG | Pharmaceutical carriers containing mirnas for use in the treatment of renal cancer |
| EP3740576A4 (en) | 2018-01-18 | 2021-10-20 | Advanced Regen Medical Technologies, LLC | THERAPEUTIC COMPOSITIONS AND THEIR PREPARATION AND USE METHODS |
| WO2019197442A1 (en) * | 2018-04-12 | 2019-10-17 | Unicyte Ev Ag | A combination of active ingredients for the treatment of tumor |
| CN111494417B (zh) * | 2020-02-10 | 2024-04-09 | 寇晓星 | 诱导性细胞外囊泡在制备治疗肿瘤药物中的应用 |
| CA3178268A1 (en) | 2020-05-11 | 2021-11-18 | Jonathan Thon | Compositions and methods related to megakaryocyte-derived extracellular vesicles |
| KR102601831B1 (ko) * | 2020-09-23 | 2023-11-14 | 대한민국 | 고형암 증식 억제 효과를 갖는 개과동물의 엑소좀 |
| EP4534649A1 (en) * | 2023-10-03 | 2025-04-09 | Unicyte AG | A method of qualifying as pharmaceutically active a batch of undifferentiated adult stem cells having the potential to differentiate along the hepatic lineage |
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| US6088613A (en) * | 1989-12-22 | 2000-07-11 | Imarx Pharmaceutical Corp. | Method of magnetic resonance focused surgical and therapeutic ultrasound |
| WO1998033486A1 (en) * | 1997-01-30 | 1998-08-06 | Quadrant Healthcare (Uk) Limited | Microparticles and their use in cancer treatment |
| ATE296113T1 (de) * | 1998-02-09 | 2005-06-15 | Bracco Research Sa | Zielgerichtete abgabe von biologische-aktive medien |
| US20020177551A1 (en) * | 2000-05-31 | 2002-11-28 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| US7128903B2 (en) * | 2001-10-03 | 2006-10-31 | Innovative Pharmaceutical Concepts (Ipc) Inc. | Pharmaceutical preparations useful for treating tumors and lesions of the skin and the mucous membranes and methods and kits using same |
| WO2005121369A2 (en) * | 2004-06-02 | 2005-12-22 | Sourcepharm, Inc. | Rna-containing microvesicles and methods therefor |
| US8148335B2 (en) * | 2004-06-23 | 2012-04-03 | Children's Hospital & Research Center Oakland | De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy |
| GB0501129D0 (en) * | 2005-01-19 | 2005-02-23 | Ribostem Ltd | Method of treatment by administration of RNA |
| WO2006126219A1 (en) | 2005-05-26 | 2006-11-30 | Fresenius Medical Care Deutschland G.M.B.H. | Liver progenitor cells |
| US20090000641A1 (en) | 2007-06-28 | 2009-01-01 | Applied Materials, Inc. | Methods and apparatus for cleaning deposition chamber parts using selective spray etch |
| ES2419129T3 (es) * | 2007-09-14 | 2013-08-19 | The Ohio State University Research Foundation | Expresión de miARN en microvesículas de sangre periférica humana y usos del mismo |
| WO2009050742A1 (en) | 2007-10-15 | 2009-04-23 | Fresenius Medial Care Deutschland Gmbh | Use of microvesicles (mvs) for preparing a medicament having adjuvant activity on endothelial cell transplantation, particularly in the treatment of diabetes by pancreatic islet transplantation, and related method |
| PL2211875T3 (pl) * | 2007-10-29 | 2013-11-29 | Fresenius Medical Care Deutschland Gmbh | Zastosowanie mikropęcherzyków (MV) pochodzących z komórek macierzystych do wytwarzania leku do regeneracji śródbłonkowej/nabłonkowej uszkodzonych lub poddanych urazowi tkanek lub narządów i związane z nimi sposoby in vitro i in vivo |
| NZ586497A (en) * | 2008-01-04 | 2012-07-27 | Lydac Neuroscience Ltd | Microvesicles |
| HUE026536T2 (en) * | 2008-02-22 | 2016-06-28 | Agency For Science Tech And Res (A Star) | Mesenchymal stem cell particles |
| EP2186883A1 (en) | 2008-11-04 | 2010-05-19 | Fresenius Medical Care | An isolated multipotent mesenchymal stem cell from human adult glomeruli (hGL-MSC), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney |
| EP2363136A1 (en) * | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
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2011
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- 2011-02-28 EP EP11705585.5A patent/EP2542250B1/en active Active
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2017
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2023
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Also Published As
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|---|---|
| US20120321723A1 (en) | 2012-12-20 |
| DK2542250T3 (en) | 2015-12-07 |
| WO2011107437A1 (en) | 2011-09-09 |
| JP5841952B2 (ja) | 2016-01-13 |
| CN102781454B (zh) | 2015-12-16 |
| EP2542250A1 (en) | 2013-01-09 |
| HUE026292T2 (en) | 2016-05-30 |
| JP2013520971A (ja) | 2013-06-10 |
| EP2363136A1 (en) | 2011-09-07 |
| US9717760B2 (en) | 2017-08-01 |
| PL2542250T3 (pl) | 2016-04-29 |
| US10105395B2 (en) | 2018-10-23 |
| US20170348356A1 (en) | 2017-12-07 |
| EP2542250B1 (en) | 2015-08-26 |
| US20190060369A1 (en) | 2019-02-28 |
| US20230248774A1 (en) | 2023-08-10 |
| PT2542250E (pt) | 2015-12-09 |
| CN102781454A (zh) | 2012-11-14 |
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