ES2535358T3 - Bibliotecas de proteínas de fusión de transferrina - Google Patents

Bibliotecas de proteínas de fusión de transferrina Download PDF

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Publication number
ES2535358T3
ES2535358T3 ES12157790.2T ES12157790T ES2535358T3 ES 2535358 T3 ES2535358 T3 ES 2535358T3 ES 12157790 T ES12157790 T ES 12157790T ES 2535358 T3 ES2535358 T3 ES 2535358T3
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ES
Spain
Prior art keywords
transferrin
protein
binding
amino acid
fusion protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12157790.2T
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English (en)
Spanish (es)
Inventor
Andrew John Turner
Baiyang Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biorexis Pharmaceutical Corp
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Biorexis Pharmaceutical Corp
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Publication of ES2535358T3 publication Critical patent/ES2535358T3/es
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79Transferrins, e.g. lactoferrins, ovotransferrins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES12157790.2T 2006-12-12 2007-12-07 Bibliotecas de proteínas de fusión de transferrina Active ES2535358T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93495106P 2006-12-12 2006-12-12
US934951P 2006-12-12

Publications (1)

Publication Number Publication Date
ES2535358T3 true ES2535358T3 (es) 2015-05-08

Family

ID=39362844

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12157790.2T Active ES2535358T3 (es) 2006-12-12 2007-12-07 Bibliotecas de proteínas de fusión de transferrina

Country Status (13)

Country Link
US (1) US8822639B2 (cg-RX-API-DMAC7.html)
EP (2) EP2114999A2 (cg-RX-API-DMAC7.html)
JP (1) JP5492563B2 (cg-RX-API-DMAC7.html)
KR (1) KR20090098880A (cg-RX-API-DMAC7.html)
CN (1) CN101622274A (cg-RX-API-DMAC7.html)
AU (1) AU2007331195A1 (cg-RX-API-DMAC7.html)
CA (1) CA2673085C (cg-RX-API-DMAC7.html)
ES (1) ES2535358T3 (cg-RX-API-DMAC7.html)
IL (1) IL198815A0 (cg-RX-API-DMAC7.html)
MX (1) MX2009006398A (cg-RX-API-DMAC7.html)
NO (1) NO20092591L (cg-RX-API-DMAC7.html)
WO (1) WO2008072075A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200904757B (cg-RX-API-DMAC7.html)

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US8401798B2 (en) * 2008-06-06 2013-03-19 Dna Twopointo, Inc. Systems and methods for constructing frequency lookup tables for expression systems
DK3252068T3 (da) 2009-10-12 2025-08-25 Larry J Smith Metoder og sammensætninger til modulering af genekspression ved anvendelse af oligonukleotidbaserede lægemidler administreret in vivo eller in vitro
CN102258767B (zh) * 2010-05-24 2013-05-15 黄敏铨 促进伤口愈合的组合物
US20130251740A1 (en) * 2010-10-26 2013-09-26 Rockefeller University (The) Immunogenic agents
EP2670421B1 (en) * 2011-02-02 2017-12-06 Medipost Co., Ltd. Use of icam-1 for prevention or treatment of neurological diseases
US9623117B2 (en) * 2011-04-04 2017-04-18 Wisconsin Alumni Research Foundation Method for selective targeting and entry of bacterial toxins to cells
HUE037849T2 (hu) 2012-06-08 2018-09-28 Alkermes Pharma Ireland Ltd Cirkuláris permutációval módosított ligandumok agonistaként és antagonistaként
AU2013359469B2 (en) * 2012-12-10 2019-05-16 Seattle Biomedical Research Institute Cell-free biofragment compositions and related systems, devices, and methods
JP7235436B2 (ja) * 2014-11-10 2023-03-08 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 細胞の表面上にポリペプチドを発現させるための組成物および方法
EP3438254A4 (en) * 2016-03-30 2019-10-16 Kaneka Corporation POLYPEPTIDE WITH ENDONUCLEASE ACTIVITY AND MANUFACTURING METHOD THEREFOR
CN109641971B (zh) * 2016-08-25 2023-04-04 Jcr制药股份有限公司 抗体融合蛋白的制造方法
US20220064245A1 (en) * 2018-12-21 2022-03-03 Vib Vzw Fusion proteins comprising a cytokine and scaffold protein
CN113045670B (zh) * 2019-12-27 2022-11-01 华南农业大学 一种可溶性鸡α干扰素融合蛋白及其生产方法与应用
KR20230160294A (ko) 2021-03-24 2023-11-23 알케르메스, 인코포레이티드 Upar 항체 및 이를 갖는 융합 단백질
WO2023114912A2 (en) * 2021-12-16 2023-06-22 Thomas Jefferson University A therapeutic against crimean-congo hemorrhagic fever virus

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Also Published As

Publication number Publication date
JP2010512160A (ja) 2010-04-22
WO2008072075A3 (en) 2008-11-06
AU2007331195A1 (en) 2008-06-19
WO2008072075A2 (en) 2008-06-19
MX2009006398A (es) 2009-06-23
CN101622274A (zh) 2010-01-06
KR20090098880A (ko) 2009-09-17
IL198815A0 (en) 2011-08-01
US20110086768A1 (en) 2011-04-14
EP2479189B1 (en) 2015-02-25
EP2479189A1 (en) 2012-07-25
NO20092591L (no) 2009-09-11
US8822639B2 (en) 2014-09-02
EP2114999A2 (en) 2009-11-11
ZA200904757B (en) 2010-04-28
JP5492563B2 (ja) 2014-05-14
CA2673085C (en) 2013-10-15
CA2673085A1 (en) 2008-06-19

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