ES2534605T3 - Agentes receptores de la histamina H3, preparación y usos terapéuticos - Google Patents
Agentes receptores de la histamina H3, preparación y usos terapéuticos Download PDFInfo
- Publication number
- ES2534605T3 ES2534605T3 ES05789881.9T ES05789881T ES2534605T3 ES 2534605 T3 ES2534605 T3 ES 2534605T3 ES 05789881 T ES05789881 T ES 05789881T ES 2534605 T3 ES2534605 T3 ES 2534605T3
- Authority
- ES
- Spain
- Prior art keywords
- pyrrolidin
- phenyl
- ylmethyl
- methanone
- thiophene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60362804P | 2004-08-23 | 2004-08-23 | |
| US603628P | 2004-08-23 | ||
| PCT/US2005/029032 WO2006023462A1 (en) | 2004-08-23 | 2005-08-15 | Histamine h3 receptor agents, preparation and therapeutic uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2534605T3 true ES2534605T3 (es) | 2015-04-24 |
Family
ID=35385793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES05789881.9T Expired - Lifetime ES2534605T3 (es) | 2004-08-23 | 2005-08-15 | Agentes receptores de la histamina H3, preparación y usos terapéuticos |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7705025B2 (enExample) |
| EP (1) | EP1784400B1 (enExample) |
| JP (1) | JP4942654B2 (enExample) |
| CN (1) | CN101006082B (enExample) |
| AU (1) | AU2005277518B2 (enExample) |
| BR (1) | BRPI0514553A (enExample) |
| CA (1) | CA2577061C (enExample) |
| ES (1) | ES2534605T3 (enExample) |
| MX (1) | MX2007002274A (enExample) |
| WO (1) | WO2006023462A1 (enExample) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8008301B2 (en) * | 2004-04-01 | 2011-08-30 | Eli Lilly And Company | Histamine H3 receptor agents, preparation and therapeutic uses |
| MX2007004479A (es) | 2004-10-13 | 2007-06-18 | Ptc Therapeutics Inc | Compuestoss para supresion sin sentido y metodos para su uso. |
| WO2006107661A1 (en) * | 2005-04-01 | 2006-10-12 | Eli Lilly And Company | Histamine h3 receptor agents, preparation and therapeutic uses |
| CA2645731A1 (en) | 2006-03-15 | 2007-09-27 | Wyeth | N-substituted-azacyclylamines as histamine-3 antagonists |
| CA2649913A1 (en) | 2006-05-19 | 2007-11-29 | Wyeth | N-benzoyl- and n-benzylpyrrolidin-3-ylamines as histamine-3 antagonists |
| WO2007143824A1 (en) * | 2006-06-13 | 2007-12-21 | Merck Frosst Canada Ltd. | Azacyclopentane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase |
| PE20081152A1 (es) * | 2006-10-06 | 2008-08-10 | Wyeth Corp | Azaciclilaminas n-sustituidas como antagonistas de histamina-3 |
| US20100070019A1 (en) * | 2006-10-29 | 2010-03-18 | Aneuwrap Ltd. | extra-vascular wrapping for treating aneurysmatic aorta and methods thereof |
| WO2008072724A1 (ja) * | 2006-12-14 | 2008-06-19 | Taisho Pharmaceutical Co., Ltd. | ピラゾール誘導体 |
| CL2008001503A1 (es) | 2007-05-24 | 2008-07-04 | Wyeth Corp | Compuestos derivados de azaciclilbenzamidas, antagonistas de histamina-3; procedimiento de preparacion; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para tratar un trastorno neurodegenerativo, como alzheimer, parkinso |
| JP2010533725A (ja) | 2007-07-16 | 2010-10-28 | ワイス・エルエルシー | ヒスタミン‐３（ｈ３）受容体としてのアミノアルキルアゾール化合物 |
| CA2705502C (en) | 2007-11-13 | 2016-01-26 | Taisho Pharmaceutical Co., Ltd. | Phenylpyrazole derivatives |
| DE102008015032A1 (de) | 2008-03-17 | 2009-09-24 | Aicuris Gmbh & Co. Kg | Substituierte Pyrazolamide und ihre Verwendung |
| DE102008015033A1 (de) | 2008-03-17 | 2009-09-24 | Aicuris Gmbh & Co. Kg | Substituierte (Pyrazolyl-carbonyl)imidazolidinone und ihre Verwendung |
| DE102008062863A1 (de) | 2008-12-17 | 2010-06-24 | Aicuris Gmbh & Co. Kg | Substituierte (Thiophenyl-carbonyl)imidazolidinone und ihre Verwendung |
| DE102008062878A1 (de) | 2008-12-17 | 2010-06-24 | Aicuris Gmbh & Co. Kg | Substituierte Furancarboxamide und ihre Verwendung |
| EP2243777A1 (de) * | 2009-04-03 | 2010-10-27 | Bayer CropScience AG | Verfahren zum Herstellen von Pyridyl-substituierten Pyrazolen |
| UA107791C2 (en) | 2009-05-05 | 2015-02-25 | Dow Agrosciences Llc | Pesticidal compositions |
| WO2010150208A2 (en) | 2009-06-23 | 2010-12-29 | Endospan Ltd. | Vascular prostheses for treating aneurysms |
| WO2011004374A1 (en) | 2009-07-09 | 2011-01-13 | Endospan Ltd. | Apparatus for closure of a lumen and methods of using the same |
| DE102009038123A1 (de) | 2009-08-17 | 2011-02-24 | Aicuris Gmbh & Co. Kg | Substituierte (Thiazolyl-carbonyl)imidazolidinone und ihre Verwendung |
| EP3735937A1 (en) | 2009-11-30 | 2020-11-11 | Endospan Ltd. | Multi-component stent-graft system for implantation in a blood vessel with multiple branches |
| US9101457B2 (en) | 2009-12-08 | 2015-08-11 | Endospan Ltd. | Endovascular stent-graft system with fenestrated and crossing stent-grafts |
| EP2533722B1 (en) | 2010-02-08 | 2017-03-29 | Endospan Ltd. | Thermal energy application for prevention and management of endoleaks in stent-grafts |
| US20110208289A1 (en) * | 2010-02-25 | 2011-08-25 | Endospan Ltd. | Flexible Stent-Grafts |
| AR081626A1 (es) | 2010-04-23 | 2012-10-10 | Cytokinetics Inc | Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos |
| AR081331A1 (es) | 2010-04-23 | 2012-08-08 | Cytokinetics Inc | Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos |
| US9133123B2 (en) | 2010-04-23 | 2015-09-15 | Cytokinetics, Inc. | Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use |
| EP2576536B1 (en) * | 2010-06-01 | 2016-09-14 | The University of Queensland | Haematopoietic-prostaglandin d2 synthase inhibitors |
| EP2635278B1 (en) | 2010-11-03 | 2019-12-11 | Dow AgroSciences LLC | Pesticidal compositions and processes related thereto |
| US9526638B2 (en) | 2011-02-03 | 2016-12-27 | Endospan Ltd. | Implantable medical devices constructed of shape memory material |
| WO2012111006A1 (en) | 2011-02-17 | 2012-08-23 | Endospan Ltd. | Vascular bands and delivery systems therefor |
| WO2012114348A1 (en) | 2011-02-23 | 2012-08-30 | Suven Life Sciences Limited | Novel compounds as histamine h3 receptor ligands |
| EP2680788A4 (en) | 2011-03-02 | 2014-12-10 | Endospan Ltd | OUTER RING WITH REDUCED VOLTAGE FOR THE TREATMENT OF AORTIC ANATOMY |
| US8759380B2 (en) | 2011-04-22 | 2014-06-24 | Cytokinetics, Inc. | Certain heterocycles, compositions thereof, and methods for their use |
| US8574287B2 (en) | 2011-06-14 | 2013-11-05 | Endospan Ltd. | Stents incorporating a plurality of strain-distribution locations |
| EP2579811B1 (en) | 2011-06-21 | 2016-03-16 | Endospan Ltd | Endovascular system with circumferentially-overlapping stent-grafts |
| US9254209B2 (en) | 2011-07-07 | 2016-02-09 | Endospan Ltd. | Stent fixation with reduced plastic deformation |
| US9839510B2 (en) | 2011-08-28 | 2017-12-12 | Endospan Ltd. | Stent-grafts with post-deployment variable radial displacement |
| UA114611C2 (uk) | 2011-10-26 | 2017-07-10 | Дау Аґросаєнсиз Елелсі | Пестицидні композиції і способи, що їх стосуються |
| WO2013065040A1 (en) | 2011-10-30 | 2013-05-10 | Endospan Ltd. | Triple-collar stent-graft |
| WO2013084235A2 (en) | 2011-12-04 | 2013-06-13 | Endospan Ltd. | Branched stent-graft system |
| EP2602248A1 (en) | 2011-12-05 | 2013-06-12 | University Of Leicester | Novel pyrrole compounds |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| US20130291227A1 (en) | 2012-04-27 | 2013-10-31 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| US9708288B2 (en) | 2012-04-27 | 2017-07-18 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| US9770350B2 (en) | 2012-05-15 | 2017-09-26 | Endospan Ltd. | Stent-graft with fixation elements that are radially confined for delivery |
| JP6225178B2 (ja) | 2012-05-31 | 2017-11-01 | フェネックス ファーマシューティカルス アーゲー | オーファン核内受容体ＲＯＲγの調整剤としてのカルボキサミドまたはスルホンアミド置換されたチアゾールおよび関連する誘導体 |
| PT2888243T (pt) | 2012-08-23 | 2016-09-21 | Suven Life Sciences Ltd | Compostos de acrilamida como ligantes de recetor h3 de histamina |
| WO2014141232A1 (en) | 2013-03-11 | 2014-09-18 | Endospan Ltd. | Multi-component stent-graft system for aortic dissections |
| US9085564B2 (en) | 2013-10-17 | 2015-07-21 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| JP2016535010A (ja) | 2013-10-17 | 2016-11-10 | ダウ アグロサイエンシィズ エルエルシー | 有害生物防除性化合物の製造方法 |
| CN105636443A (zh) | 2013-10-17 | 2016-06-01 | 美国陶氏益农公司 | 制备杀虫化合物的方法 |
| CN105636441B (zh) | 2013-10-17 | 2018-06-15 | 美国陶氏益农公司 | 制备杀虫化合物的方法 |
| JP6487426B2 (ja) | 2013-10-17 | 2019-03-20 | ダウ アグロサイエンシィズ エルエルシー | 有害生物防除化合物の調製法 |
| KR20160072155A (ko) | 2013-10-17 | 2016-06-22 | 다우 아그로사이언시즈 엘엘씨 | 살충성 화합물의 제조 방법 |
| MX2016004940A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Proceso para la preparacion de compuestos plaguicidas. |
| AR098099A1 (es) | 2013-10-22 | 2016-05-04 | Dow Agrosciences Llc | Composiciones plaguicidas sinérgicas y los métodos relacionados |
| WO2015061146A1 (en) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| NZ719968A (en) | 2013-10-22 | 2017-05-26 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
| CA2926433A1 (en) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
| EP3060043B1 (en) | 2013-10-22 | 2025-11-26 | Corteva Agriscience LLC | Pesticidal compositions and related methods |
| WO2015061148A1 (en) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| US9801376B2 (en) | 2013-10-22 | 2017-10-31 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| JP2016538266A (ja) | 2013-10-22 | 2016-12-08 | ダウ アグロサイエンシィズ エルエルシー | 相乗的有害生物防除組成物および関連する方法 |
| RU2667777C2 (ru) | 2013-10-22 | 2018-09-24 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Пестицидные композиции и связанные с ними способы |
| MX2016005319A (es) | 2013-10-22 | 2016-08-12 | Dow Agrosciences Llc | Composiciones pesticidas y metodos relacionados. |
| TW201519777A (zh) | 2013-10-22 | 2015-06-01 | Dow Agrosciences Llc | 協同性殺蟲組成物及相關方法（九） |
| KR20160074632A (ko) | 2013-10-22 | 2016-06-28 | 다우 아그로사이언시즈 엘엘씨 | 상승작용적 살충 조성물 및 관련 방법 |
| AU2014340412B2 (en) | 2013-10-22 | 2017-04-20 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| RU2016119553A (ru) | 2013-10-22 | 2017-12-04 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Синергетические пестицидные композиции и связанные с ними способы |
| CN105848482A (zh) | 2013-10-22 | 2016-08-10 | 美国陶氏益农公司 | 协同杀虫组合物和相关方法 |
| TW201519783A (zh) | 2013-10-22 | 2015-06-01 | Dow Agrosciences Llc | 殺蟲組成物及相關方法（四） |
| AR098090A1 (es) | 2013-10-22 | 2016-05-04 | Dow Agrosciences Llc | Composiciones plaguicidas sinérgicas y métodos relacionados |
| US10603197B2 (en) | 2013-11-19 | 2020-03-31 | Endospan Ltd. | Stent system with radial-expansion locking |
| US9249122B1 (en) | 2014-07-31 | 2016-02-02 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
| JP2017523163A (ja) | 2014-07-31 | 2017-08-17 | ダウ アグロサイエンシィズ エルエルシー | ３−（３−クロロ−１ｈ−ピラゾール−１−イル）ピリジンの製造方法 |
| BR112017000418A2 (pt) | 2014-07-31 | 2017-11-07 | Dow Agrosciences Llc | processo para a preparação de 3-(3-cloro-1h-pirazol-1-il)piridina |
| US9024031B1 (en) | 2014-08-19 | 2015-05-05 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
| EP3191455A4 (en) | 2014-09-12 | 2018-01-24 | Dow AgroSciences LLC | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
| WO2016098113A1 (en) | 2014-12-18 | 2016-06-23 | Endospan Ltd. | Endovascular stent-graft with fatigue-resistant lateral tube |
| KR101613245B1 (ko) | 2015-04-27 | 2016-04-18 | 주식회사 대웅제약 | 신규의 4-메톡시 피롤 유도체 또는 이의 염 및 이를 포함하는 약학 조성물 |
| WO2018125817A1 (en) | 2016-12-29 | 2018-07-05 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| WO2018125815A1 (en) | 2016-12-29 | 2018-07-05 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| JP7362916B2 (ja) * | 2019-10-30 | 2023-10-17 | ドンバオ・パープル・スター・（ハンジョウ）・バイオファーマシューティカル・カンパニー・リミテッド | キサンチンオキシダーゼ阻害剤としてのチオフェン誘導体およびその使用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2579596B1 (fr) | 1985-03-26 | 1987-11-20 | Inst Nat Sante Rech Med | (imidazolyl-4) piperidines, leur preparation et leur application en therapeutique |
| FR2671083B1 (fr) | 1990-12-31 | 1994-12-23 | Inst Nat Sante Rech Med | Nouvelles 4-(4-imidazolyl) piperidines substituees en 1, leur preparation ainsi que leurs applications therapeutiques. |
| US5652258A (en) | 1995-05-30 | 1997-07-29 | Gliatech, Inc. | 2-(4-imidazoyl) cyclopropyl derivatives |
| AU721325B2 (en) | 1995-05-30 | 2000-06-29 | Gliatech Inc. | 1H-4(5)-substituted imidazole derivatives |
| AU709611B2 (en) | 1996-02-09 | 1999-09-02 | James Black Foundation Limited | Histamine h3 receptor ligands |
| CA2441080A1 (en) | 2001-03-23 | 2002-10-03 | Eli Lilly And Company | Non-imidazole aryl alkylamines compounds as histamine h3 receptor antagonists, preparation and therapeutic uses |
| IL162834A0 (en) * | 2002-02-01 | 2005-11-20 | Novo Nordisk As | Amides of aminoalkyl-substituted azetidines, pyrrolidines, piperidines and azepanes |
| ES2502490T3 (es) | 2003-02-26 | 2014-10-03 | Sugen, Inc. | Compuestos aminoheteroarílicos como inhibidores de proteín quinasas |
| US7632857B2 (en) * | 2004-04-01 | 2009-12-15 | Eli Lilly And Company | Histamine H3 receptor agents, preparation and therapeutic uses |
-
2005
- 2005-08-15 CA CA2577061A patent/CA2577061C/en not_active Expired - Fee Related
- 2005-08-15 BR BRPI0514553-8A patent/BRPI0514553A/pt not_active IP Right Cessation
- 2005-08-15 MX MX2007002274A patent/MX2007002274A/es active IP Right Grant
- 2005-08-15 EP EP05789881.9A patent/EP1784400B1/en not_active Expired - Lifetime
- 2005-08-15 WO PCT/US2005/029032 patent/WO2006023462A1/en not_active Ceased
- 2005-08-15 AU AU2005277518A patent/AU2005277518B2/en not_active Ceased
- 2005-08-15 CN CN200580028163XA patent/CN101006082B/zh not_active Expired - Fee Related
- 2005-08-15 JP JP2007529947A patent/JP4942654B2/ja not_active Expired - Fee Related
- 2005-08-15 ES ES05789881.9T patent/ES2534605T3/es not_active Expired - Lifetime
- 2005-08-15 US US11/574,044 patent/US7705025B2/en not_active Expired - Fee Related
-
2009
- 2009-10-13 US US12/577,843 patent/US20100029608A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101006082A (zh) | 2007-07-25 |
| WO2006023462A1 (en) | 2006-03-02 |
| US7705025B2 (en) | 2010-04-27 |
| JP2008510808A (ja) | 2008-04-10 |
| AU2005277518A1 (en) | 2006-03-02 |
| US20090048225A1 (en) | 2009-02-19 |
| AU2005277518B2 (en) | 2011-08-04 |
| CA2577061A1 (en) | 2006-03-02 |
| CA2577061C (en) | 2014-02-18 |
| MX2007002274A (es) | 2007-05-07 |
| EP1784400A1 (en) | 2007-05-16 |
| EP1784400B1 (en) | 2015-01-14 |
| CN101006082B (zh) | 2010-09-29 |
| BRPI0514553A (pt) | 2008-06-17 |
| US20100029608A1 (en) | 2010-02-04 |
| JP4942654B2 (ja) | 2012-05-30 |
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