ES2530345T3 - Derivados de pirazolopiridinona como antagonistas del receptor del LPA - Google Patents

Derivados de pirazolopiridinona como antagonistas del receptor del LPA Download PDF

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Publication number
ES2530345T3
ES2530345T3 ES11741410T ES11741410T ES2530345T3 ES 2530345 T3 ES2530345 T3 ES 2530345T3 ES 11741410 T ES11741410 T ES 11741410T ES 11741410 T ES11741410 T ES 11741410T ES 2530345 T3 ES2530345 T3 ES 2530345T3
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alkyl
aryl
heterocyclyl
cycloalkyl
heteroaryl
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Spanish (es)
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Kai Schiemann
Wolfgang Staehle
Dirk Wienke
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Merck Patent GmbH
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Merck Patent GmbH
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Medicinal Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
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  • Pain & Pain Management (AREA)
  • AIDS & HIV (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
ES11741410T 2010-09-02 2011-08-05 Derivados de pirazolopiridinona como antagonistas del receptor del LPA Active ES2530345T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10009117 2010-09-02
PCT/EP2011/003949 WO2012028243A1 (en) 2010-09-02 2011-08-05 Pyrazolopyridinone derivatives as lpa receptor antagonists

Publications (1)

Publication Number Publication Date
ES2530345T3 true ES2530345T3 (es) 2015-03-02

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ES11741410T Active ES2530345T3 (es) 2010-09-02 2011-08-05 Derivados de pirazolopiridinona como antagonistas del receptor del LPA

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US (2) US8859775B2 (cg-RX-API-DMAC7.html)
EP (1) EP2611808B1 (cg-RX-API-DMAC7.html)
JP (1) JP6039559B2 (cg-RX-API-DMAC7.html)
CN (1) CN103189378B (cg-RX-API-DMAC7.html)
AR (1) AR082880A1 (cg-RX-API-DMAC7.html)
AU (1) AU2011297961B2 (cg-RX-API-DMAC7.html)
CA (1) CA2809892C (cg-RX-API-DMAC7.html)
ES (1) ES2530345T3 (cg-RX-API-DMAC7.html)
IL (1) IL225015A (cg-RX-API-DMAC7.html)
WO (1) WO2012028243A1 (cg-RX-API-DMAC7.html)

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CA2809892A1 (en) 2012-03-08
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CN103189378A (zh) 2013-07-03
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AR082880A1 (es) 2013-01-16
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