ES2523591T3 - Derivados de ácidos biliares como ligandos de FXR para la prevención o el tratamiento de enfermedades o estados mediados por FXR - Google Patents
Derivados de ácidos biliares como ligandos de FXR para la prevención o el tratamiento de enfermedades o estados mediados por FXR Download PDFInfo
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- ES2523591T3 ES2523591T3 ES07809913.2T ES07809913T ES2523591T3 ES 2523591 T3 ES2523591 T3 ES 2523591T3 ES 07809913 T ES07809913 T ES 07809913T ES 2523591 T3 ES2523591 T3 ES 2523591T3
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- disease
- compound
- fxr
- pharmaceutically acceptable
- bile
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
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| PCT/US2007/014829 WO2008002573A2 (en) | 2006-06-27 | 2007-06-27 | Bile acid derivatives as fxr ligands for the prevention or treatment of fxr-mediated deseases or conditions |
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2007
- 2007-06-27 ES ES07809913.2T patent/ES2523591T3/es active Active
- 2007-06-27 PT PT78099132T patent/PT2040713E/pt unknown
- 2007-06-27 DK DK07809913.2T patent/DK2040713T3/da active
- 2007-06-27 CA CA2656320A patent/CA2656320C/en active Active
- 2007-06-27 US US11/819,517 patent/US7932244B2/en active Active
- 2007-06-27 JP JP2009518230A patent/JP5222846B2/ja not_active Expired - Fee Related
- 2007-06-27 SI SI200731515T patent/SI2040713T1/sl unknown
- 2007-06-27 AU AU2007265457A patent/AU2007265457C1/en not_active Ceased
- 2007-06-27 CN CN2007800321119A patent/CN101522703B/zh not_active Expired - Fee Related
- 2007-06-27 EP EP07809913.2A patent/EP2040713B1/en active Active
- 2007-06-27 WO PCT/US2007/014829 patent/WO2008002573A2/en not_active Ceased
- 2007-06-27 PL PL07809913T patent/PL2040713T3/pl unknown
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2008
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2011
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- 2013-08-28 US US14/012,401 patent/US9090652B2/en not_active Expired - Fee Related
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2014
- 2014-09-16 CY CY20141100746T patent/CY1115533T1/el unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2007265457C1 (en) | 2012-11-29 |
| WO2008002573A3 (en) | 2008-02-28 |
| EP2040713A2 (en) | 2009-04-01 |
| IL221764A0 (en) | 2012-10-31 |
| CA2656320A1 (en) | 2008-01-03 |
| US20120283234A1 (en) | 2012-11-08 |
| JP5222846B2 (ja) | 2013-06-26 |
| US20140057886A1 (en) | 2014-02-27 |
| PL2040713T3 (pl) | 2014-11-28 |
| US8546365B2 (en) | 2013-10-01 |
| SI2040713T1 (sl) | 2014-11-28 |
| DK2040713T3 (da) | 2014-09-29 |
| IL196169A (en) | 2012-10-31 |
| CY1115533T1 (el) | 2017-01-04 |
| US20080182832A1 (en) | 2008-07-31 |
| HK1130187A1 (en) | 2009-12-24 |
| EP2040713A4 (en) | 2012-08-29 |
| JP2010500285A (ja) | 2010-01-07 |
| IL196169A0 (en) | 2009-09-22 |
| WO2008002573A2 (en) | 2008-01-03 |
| CN101522703B (zh) | 2013-04-17 |
| CA2656320C (en) | 2015-04-28 |
| PT2040713E (pt) | 2014-10-13 |
| IL221764A (en) | 2016-09-29 |
| US9090652B2 (en) | 2015-07-28 |
| AU2007265457B2 (en) | 2012-06-14 |
| AU2007265457A1 (en) | 2008-01-03 |
| US20150359805A1 (en) | 2015-12-17 |
| EP2040713B1 (en) | 2014-06-18 |
| CN101522703A (zh) | 2009-09-02 |
| US7932244B2 (en) | 2011-04-26 |
| US9763964B2 (en) | 2017-09-19 |
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