ES2483996T3 - Sistemas y métodos de tratamiento de los huesos - Google Patents
Sistemas y métodos de tratamiento de los huesos Download PDFInfo
- Publication number
- ES2483996T3 ES2483996T3 ES09715413.2T ES09715413T ES2483996T3 ES 2483996 T3 ES2483996 T3 ES 2483996T3 ES 09715413 T ES09715413 T ES 09715413T ES 2483996 T3 ES2483996 T3 ES 2483996T3
- Authority
- ES
- Spain
- Prior art keywords
- polymer
- polymer particles
- volume
- bpo
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 210000000988 bone and bone Anatomy 0.000 title 1
- 229920000642 polymer Polymers 0.000 abstract 12
- 239000002245 particle Substances 0.000 abstract 9
- 239000004342 Benzoyl peroxide Substances 0.000 abstract 5
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 abstract 5
- 235000019400 benzoyl peroxide Nutrition 0.000 abstract 5
- 229920003229 poly(methyl methacrylate) Polymers 0.000 abstract 4
- 239000002639 bone cement Substances 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000004926 polymethyl methacrylate Substances 0.000 abstract 3
- 239000000843 powder Substances 0.000 abstract 3
- 239000000178 monomer Substances 0.000 abstract 2
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
- A61L24/0094—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing macromolecular fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7094—Solid vertebral fillers; devices for inserting such fillers
- A61B17/7095—Solid vertebral fillers; devices for inserting such fillers the filler comprising unlinked macroscopic particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
- A61B17/8822—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it characterised by means facilitating expulsion of fluid from the introducer, e.g. a screw pump plunger, hydraulic force transmissions, application of vibrations or a vacuum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8833—Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8833—Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means
- A61B17/8836—Osteosynthesis tools specially adapted for handling bone cement or fluid fillers; Means for supplying bone cement or fluid fillers to introducing tools, e.g. cartridge handling means for heating, cooling or curing of bone cement or fluid fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
- A61L24/0084—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing fillers of phosphorus-containing inorganic compounds, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
- A61L24/0089—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing inorganic fillers not covered by groups A61L24/0078 or A61L24/0084
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Medicinal Chemistry (AREA)
- Composite Materials (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials For Medical Uses (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6747908P | 2008-02-28 | 2008-02-28 | |
| US6748008P | 2008-02-28 | 2008-02-28 | |
| US67480P | 2008-02-28 | ||
| US67479P | 2008-02-28 | ||
| US12433808P | 2008-04-16 | 2008-04-16 | |
| US12433608P | 2008-04-16 | 2008-04-16 | |
| US124336P | 2008-04-16 | ||
| US124338P | 2008-04-16 | ||
| US19037508P | 2008-08-28 | 2008-08-28 | |
| US190375P | 2008-08-28 | ||
| PCT/US2009/035549 WO2009108893A2 (en) | 2008-02-28 | 2009-02-27 | Bone treatment systems and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2483996T3 true ES2483996T3 (es) | 2014-08-08 |
Family
ID=40873304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09715413.2T Active ES2483996T3 (es) | 2008-02-28 | 2009-02-27 | Sistemas y métodos de tratamiento de los huesos |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8487021B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2252336B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5509098B2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2483996T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009108893A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8361067B2 (en) | 2002-09-30 | 2013-01-29 | Relievant Medsystems, Inc. | Methods of therapeutically heating a vertebral body to treat back pain |
| US7722620B2 (en) | 2004-12-06 | 2010-05-25 | Dfine, Inc. | Bone treatment systems and methods |
| US8777479B2 (en) | 2008-10-13 | 2014-07-15 | Dfine, Inc. | System for use in bone cement preparation and delivery |
| US8540723B2 (en) | 2009-04-14 | 2013-09-24 | Dfine, Inc. | Medical system and method of use |
| WO2008137428A2 (en) | 2007-04-30 | 2008-11-13 | Dfine, Inc. | Bone treatment systems and methods |
| US9597118B2 (en) | 2007-07-20 | 2017-03-21 | Dfine, Inc. | Bone anchor apparatus and method |
| US9445854B2 (en) | 2008-02-01 | 2016-09-20 | Dfine, Inc. | Bone treatment systems and methods |
| US9161798B2 (en) * | 2008-02-01 | 2015-10-20 | Dfine, Inc. | Bone treatment systems and methods |
| US20100030220A1 (en) * | 2008-07-31 | 2010-02-04 | Dfine, Inc. | Bone treatment systems and methods |
| JP5509098B2 (ja) * | 2008-02-28 | 2014-06-04 | ディーエフアイエヌイー・インコーポレーテッド | 骨治療システムおよび方法 |
| US9180416B2 (en) | 2008-04-21 | 2015-11-10 | Dfine, Inc. | System for use in bone cement preparation and delivery |
| JP5688022B2 (ja) | 2008-09-26 | 2015-03-25 | リリーバント メドシステムズ、インコーポレイテッド | 骨の内部を通って器具を誘導するためのシステムおよび方法 |
| US10028753B2 (en) | 2008-09-26 | 2018-07-24 | Relievant Medsystems, Inc. | Spine treatment kits |
| BR112012004038A2 (pt) * | 2009-09-01 | 2016-03-29 | Synthes Gmbh | cimento ósseo que contém medula óssea |
| DE102009043550A1 (de) * | 2009-09-30 | 2011-05-19 | Aap Biomaterials Gmbh | Knochenzement und Verfahren zu dessen Herstellung |
| US8795369B1 (en) | 2010-07-16 | 2014-08-05 | Nuvasive, Inc. | Fracture reduction device and methods |
| CN103298430B (zh) * | 2010-09-21 | 2016-01-13 | 斯伯威丁股份公司 | 用于修复人或动物关节的装置 |
| JP5927297B2 (ja) * | 2011-08-18 | 2016-06-01 | ミリッツ マティーアス | 骨拡大のための医療装置 |
| US10390877B2 (en) | 2011-12-30 | 2019-08-27 | Relievant Medsystems, Inc. | Systems and methods for treating back pain |
| KR20140132345A (ko) * | 2012-02-29 | 2014-11-17 | 이시하라 산교 가부시끼가이샤 | 골 시멘트 조성물 |
| US10588691B2 (en) | 2012-09-12 | 2020-03-17 | Relievant Medsystems, Inc. | Radiofrequency ablation of tissue within a vertebral body |
| CA3093398C (en) | 2012-11-05 | 2022-05-24 | Relievant Medsystems, Inc. | Systems and methods for creating curved paths through bone and modulating nerves within the bone |
| TW201422268A (zh) * | 2012-12-07 | 2014-06-16 | Ind Tech Res Inst | 填充裝置及其加熱裝置 |
| US9724151B2 (en) | 2013-08-08 | 2017-08-08 | Relievant Medsystems, Inc. | Modulating nerves within bone using bone fasteners |
| AU2014326370B2 (en) | 2013-09-30 | 2017-07-27 | Lucite International Speciality Polymers & Resins Limited | A hardenable multi-part acrylic composition |
| GB201317299D0 (en) * | 2013-09-30 | 2013-11-13 | Lucite Int Uk Ltd | A hardenable multi-part acrylic composition |
| WO2017066190A1 (en) * | 2015-10-12 | 2017-04-20 | Merit Medical Systems, Inc. | Devices for performing a medical procedure within an appropriate interval and related systems and methods |
| FR3053239B1 (fr) * | 2016-06-30 | 2022-02-25 | Teknimed | Susbtitut osseux et systeme d'injection autonome |
| CN106620841B (zh) * | 2016-12-22 | 2019-09-03 | 宁波华科润生物科技有限公司 | 低温可注射丙烯酸树脂骨水泥及其制备方法 |
| AU2018242783B2 (en) * | 2017-03-31 | 2021-01-07 | Mitsui Chemicals, Inc. | Hard tissue repair composition and hard tissue repair kit |
| DE102017113126A1 (de) * | 2017-06-14 | 2018-12-20 | Heraeus Medical Gmbh | Knochenzementapplikator mit Leitungselement und Verschlussaufnahme |
| CA3094607C (en) * | 2018-03-20 | 2023-08-15 | Mitsui Chemicals, Inc. | Composition for hard tissue repair and kit for hard tissue repair |
| CN108714250A (zh) * | 2018-05-30 | 2018-10-30 | 上海尚融生物科技有限公司 | 一种凝胶状快速聚合骨填充材料及其制备方法 |
| EP4027912B1 (en) | 2019-09-12 | 2024-12-18 | Relievant Medsystems, Inc. | Systems for tissue modulation |
| CN111388759B (zh) * | 2020-04-28 | 2021-09-07 | 四川大学 | 一种骨水泥复合材料及其制备方法 |
| WO2022011115A1 (en) | 2020-07-10 | 2022-01-13 | Relievant Medsystems, Inc. | Vertebral denervation in conjunction with vertebral fusion |
| US12082876B1 (en) | 2020-09-28 | 2024-09-10 | Relievant Medsystems, Inc. | Introducer drill |
| AU2021409967A1 (en) | 2020-12-22 | 2023-08-03 | Relievant Medsystems, Inc. | Prediction of candidates for spinal neuromodulation |
| EP4312805A4 (en) * | 2021-03-23 | 2025-02-12 | RevBio, Inc. | IMAGE-GUIDED ADMINISTRATION OF COMPOSITIONS AND RELATED METHODS |
| US12433668B1 (en) | 2021-11-08 | 2025-10-07 | Relievant Medsystems, Inc. | Impedance stoppage mitigation during radiofrequency tissue ablation procedures |
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| US2496908A (en) | 1949-04-20 | 1950-02-07 | Alfred W Doux | Serving device |
| US3349840A (en) | 1965-04-05 | 1967-10-31 | Whirlpool Co | Fluid flow control apparatus |
| US3629187A (en) * | 1969-06-25 | 1971-12-21 | Dentsply Int Inc | Dental compositions containing adduct of 2 2' - propane bis 3-(4-phenoxy)-1 2-hydroxy propane - 1 - methacrylate and isocyanate |
| US4265618A (en) | 1977-09-09 | 1981-05-05 | Solar Energy Technology, Inc. | Electrically heated endodontic syringe for injecting thermoplastic material into a root canal cavity |
| DE2758374A1 (de) | 1977-12-28 | 1979-07-12 | Hilti Ag | Spreizduebel |
| US4294251A (en) | 1978-10-17 | 1981-10-13 | Greenwald A Seth | Method of suction lavage |
| US4281420A (en) | 1979-02-15 | 1981-08-04 | Raab S | Bone connective prostheses adapted to maximize strength and durability of prostheses-bone cement interface; and methods of forming same |
| US4250887A (en) | 1979-04-18 | 1981-02-17 | Dardik Surgical Associates, P.A. | Remote manual injecting apparatus |
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| JPS62182146A (ja) | 1985-10-11 | 1987-08-10 | 三井東圧化学株式会社 | 硬化性材料 |
| WO1988003811A1 (en) | 1986-11-19 | 1988-06-02 | Laboratorium Für Experimentelle Chirurgie, Forschu | Method and apparatus for preparing a self-curing two-component powder liquid bone cement |
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| US4837279A (en) | 1988-02-22 | 1989-06-06 | Pfizer Hospital Products Corp, Inc. | Bone cement |
| US4910259A (en) | 1988-09-26 | 1990-03-20 | Wolff & Kaaber A/S | Bone cement |
| US4963151A (en) | 1988-12-28 | 1990-10-16 | Trustees Of The University Of Pennsylvania | Reinforced bone cement, method of production thereof and reinforcing fiber bundles therefor |
| US4969888A (en) | 1989-02-09 | 1990-11-13 | Arie Scholten | Surgical protocol for fixation of osteoporotic bone using inflatable device |
| DE3919534A1 (de) | 1989-06-15 | 1990-12-20 | Merck Patent Gmbh | Verfahren und einrichtung zum vorbereiten von knochenzement |
| US5037437B1 (en) | 1990-01-18 | 1998-04-14 | Univ Washington | Method of bone preparation for prosthetic fixation |
| US5130950A (en) | 1990-05-16 | 1992-07-14 | Schlumberger Technology Corporation | Ultrasonic measurement apparatus |
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| US20090247664A1 (en) | 2009-10-01 |
| US9821085B2 (en) | 2017-11-21 |
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| EP2810664B1 (en) | 2019-05-29 |
| US20160058906A1 (en) | 2016-03-03 |
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| US20140031450A1 (en) | 2014-01-30 |
| EP2252336B1 (en) | 2014-06-25 |
| WO2009108893A2 (en) | 2009-09-03 |
| EP2810664A1 (en) | 2014-12-10 |
| US8487021B2 (en) | 2013-07-16 |
| US9216195B2 (en) | 2015-12-22 |
| EP2252336A2 (en) | 2010-11-24 |
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