ES2432353T3 - Inhalador de polvo seco - Google Patents

Inhalador de polvo seco Download PDF

Info

Publication number
ES2432353T3
ES2432353T3 ES01905307T ES01905307T ES2432353T3 ES 2432353 T3 ES2432353 T3 ES 2432353T3 ES 01905307 T ES01905307 T ES 01905307T ES 01905307 T ES01905307 T ES 01905307T ES 2432353 T3 ES2432353 T3 ES 2432353T3
Authority
ES
Spain
Prior art keywords
inhaler
chamber
dispersion chamber
account
inlet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES01905307T
Other languages
English (en)
Spanish (es)
Inventor
Michael Ligotke
Andrew W. Gieschen
Robert F. Eisele
Thomas F. Jackson
Jeffrey Chen
Bernard Greenspan
Clyde Witham
Gary Ward
Charles Ganem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quadrant Technologies Ltd
Original Assignee
Quadrant Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadrant Technologies Ltd filed Critical Quadrant Technologies Ltd
Application granted granted Critical
Publication of ES2432353T3 publication Critical patent/ES2432353T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0031—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043—Non-destructive separation of the package, e.g. peeling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/43—General characteristics of the apparatus making noise when used correctly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/18—Coaxial flows, e.g. one flow within another

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
ES01905307T 2000-02-01 2001-01-31 Inhalador de polvo seco Expired - Lifetime ES2432353T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US495494 2000-02-01
US09/495,494 US6427688B1 (en) 2000-02-01 2000-02-01 Dry powder inhaler
PCT/US2001/003248 WO2001056640A1 (en) 2000-02-01 2001-01-31 Dry powder inhaler

Publications (1)

Publication Number Publication Date
ES2432353T3 true ES2432353T3 (es) 2013-12-02

Family

ID=23968860

Family Applications (1)

Application Number Title Priority Date Filing Date
ES01905307T Expired - Lifetime ES2432353T3 (es) 2000-02-01 2001-01-31 Inhalador de polvo seco

Country Status (7)

Country Link
US (5) US6427688B1 (cg-RX-API-DMAC7.html)
EP (1) EP1307256B1 (cg-RX-API-DMAC7.html)
JP (1) JP4886143B2 (cg-RX-API-DMAC7.html)
AU (1) AU2001233201A1 (cg-RX-API-DMAC7.html)
CA (1) CA2398815C (cg-RX-API-DMAC7.html)
ES (1) ES2432353T3 (cg-RX-API-DMAC7.html)
WO (1) WO2001056640A1 (cg-RX-API-DMAC7.html)

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US6511676B1 (en) * 1999-11-05 2003-01-28 Teni Boulikas Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
US6651655B1 (en) 2000-01-18 2003-11-25 Quadrant Technologies Limited Inhaled vaccines
US6427688B1 (en) * 2000-02-01 2002-08-06 Dura Pharmaceuticals, Icn. Dry powder inhaler
US7171965B2 (en) * 2000-02-01 2007-02-06 Valois S.A.S. Breath actuated dry powder inhaler and tape dose strip
US7069929B2 (en) * 2000-02-01 2006-07-04 Quadrant Technologies Limited Dry powder inhaler
US6595210B2 (en) * 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
FI20010538A0 (fi) * 2001-03-16 2001-03-16 Orion Corp Jauheinhalaattori
GB2375308A (en) * 2001-05-10 2002-11-13 Cambridge Consultants Inhalers
EP1392383A2 (en) * 2001-05-10 2004-03-03 Vectura Delivery Devices Limited Inhalers
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
JP2004195191A (ja) * 2002-10-22 2004-07-15 Akihiko Miyamoto 呼子付喘息治療薬吸入器
AU2002952683A0 (en) * 2002-11-15 2002-11-28 Commonwealth Scientific And Industrial Research Organisation Apparatus for delivering dry aerosols to the respiratory tract
BR0316924A (pt) * 2002-12-02 2005-10-18 Univ Alberta Dispositivo e método para desaglomeração de pó para inalação
BR0316603B1 (pt) * 2002-12-13 2014-03-11 Otsuka Pharma Co Ltd Dispositivo de inalação para administração transpulmonar
US6941947B2 (en) * 2002-12-18 2005-09-13 Quadrant Technologies Limited Unit dose dry powder inhaler
US20040206350A1 (en) * 2002-12-19 2004-10-21 Nektar Therapeutics Aerosolization apparatus with non-circular aerosolization chamber
US8869794B1 (en) 2003-04-09 2014-10-28 Novartis Pharma Ag Aerosolization apparatus with capsule puncturing member
KR101066788B1 (ko) 2003-04-09 2011-09-21 노바르티스 아게 공기 입구 차폐 부재를 갖춘 에어로졸화 장치
GB0313604D0 (en) * 2003-06-12 2003-07-16 Britannia Pharmaceuticals Ltd Delivery device for powdered medicament
EP1635762B1 (en) * 2003-06-13 2021-03-03 Civitas Therapeutics, Inc. Low dose pharmaceutical powders for inhalation
US20050263153A1 (en) * 2004-05-28 2005-12-01 Quadrant Technologies Limited Unit dose dry powder inhaler
US7556035B2 (en) * 2004-05-28 2009-07-07 Quadrant Technologies Limited Unit dose dry powder inhaler
DE602005024413D1 (de) 2004-08-20 2010-12-09 Mannkind Corp Katalyse der diketopiperazinsynthese
CN104436170B (zh) 2004-08-23 2018-02-23 曼金德公司 用于药物输送的二酮哌嗪盐
EP1802669B1 (en) * 2004-10-21 2011-03-09 Basell Polyolefine GmbH 1-butene polymer and process for the preparation thereof
BRPI0516701B1 (pt) * 2004-11-10 2017-11-28 Cipla Ltd. Inhaler device for inhalation of a medication of a perforable capsule
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
NZ555501A (en) 2004-11-24 2010-01-29 Medpointe Healthcare Inc Compositions comprising azelastine and methods of use thereof
FR2881117B1 (fr) * 2005-01-25 2010-07-30 Valois Sas Dispositif de distribution de produit fluide.
FR2881118B1 (fr) * 2005-01-25 2007-04-20 Valois Sas Dispositif de distribution de produit fluide.
US7407156B2 (en) * 2005-03-22 2008-08-05 Toshiba Tec Kabushiki Kaisha Sheet finishing apparatus
US8763605B2 (en) 2005-07-20 2014-07-01 Manta Devices, Llc Inhalation device
JP5167133B2 (ja) 2005-09-14 2013-03-21 マンカインド コーポレイション 結晶性微粒子表面に対する活性薬剤の親和性の増大に基づく薬物処方の方法
GB0520794D0 (en) * 2005-10-12 2005-11-23 Innovata Biomed Ltd Inhaler
DE102005057685A1 (de) * 2005-12-01 2007-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator und Speicher für eine trockene Arzneimittelformulierung sowie diesbezügliche Verfahren und Verwendung
US7832397B2 (en) * 2005-12-28 2010-11-16 Philip Morris Usa Inc. Aerosol powder delivery device
GB2433207B (en) * 2006-02-21 2009-01-07 Jianhe Li Active suction actuated inhalers with timing devices
MX2008010721A (es) 2006-02-22 2008-09-01 Mannkind Corp Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo.
JP5188991B2 (ja) * 2006-03-03 2013-04-24 エスティーシー．ユーエヌエム 空力弾性分配メカニズムを有するドライパウダー吸入器
GB0611659D0 (en) * 2006-06-13 2006-07-19 Cambridge Consultants Dry powder inhalers
AP2007000277S (en) * 2007-03-28 2007-10-04 Xerxes Rao Cartridge for multidose inhaler
CA2683724A1 (en) * 2007-04-30 2009-01-15 Sun Pharma Advanced Research Company Limited Inhalation device
EP1992376A1 (en) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
US11224704B2 (en) 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
EP2898914B1 (en) * 2007-07-06 2018-06-20 Manta Devices, LLC Inhalation devices for storing and delivering medicament
EP2224983B1 (en) 2007-12-20 2017-05-10 AstraZeneca AB Device and method for deaggregating powder 854
EP2082762A1 (en) * 2008-01-24 2009-07-29 Boehringer Ingelheim International Gmbh Inhaler
EP2082764A1 (en) * 2008-01-24 2009-07-29 Boehringer Ingelheim International GmbH Inhaler
PT2254629E (pt) * 2008-03-27 2016-03-02 Mannkind Corp Um sistema de inalação de pó seco
GB2459257B (en) * 2008-04-14 2012-12-19 Alchemy Healthcare Ltd Particulate dispenser
JP5421362B2 (ja) 2008-06-13 2014-02-19 マンカインド コーポレイション 薬物送達用の乾燥粉末吸入器およびシステム
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
RU2470681C2 (ru) 2008-06-20 2012-12-27 Маннкайнд Корпорейшн Интерактивное устройство и способ профилирования усилий при ингаляции в реальном масштабе времени
FR2933619B1 (fr) * 2008-07-11 2012-03-30 Valois Sas Dispositif d'inhalation de poudre
FR2933620B1 (fr) * 2008-07-11 2010-09-03 Valois Sa Dispositif d'inhalation de poudre.
WO2010011329A2 (en) * 2008-07-23 2010-01-28 Map Pharmaceuticals, Inc. The delivery of powdered drug via inhalation
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
FR2936424B1 (fr) * 2008-09-30 2012-01-20 Valois Sas Dispositif d'inhalation de poudre.
FR2936425B1 (fr) * 2008-09-30 2012-02-17 Valois Sas Dispositif d'inhalation de poudre.
GB0818476D0 (en) * 2008-10-09 2008-11-12 Vectura Delivery Device Ltd Inhaler
BRPI0922255A2 (pt) * 2008-12-15 2016-01-12 Profibrix Bv dispositivo para fornecimento de soluções em pó
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US8550074B2 (en) 2009-01-15 2013-10-08 Manta Devices, Llc Delivery device and related methods
EP2405963B1 (en) 2009-03-11 2013-11-06 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
FR2946537B1 (fr) * 2009-06-11 2012-08-03 Valois Sas Dispositif d'inhalation de poudre
FR2946538B1 (fr) * 2009-06-11 2012-08-03 Valois Sas Dispositif d'inhalation de poudre
US8551528B2 (en) 2009-06-12 2013-10-08 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
CA2765497A1 (en) 2009-07-01 2011-01-06 Astrazeneca Ab Dispenser and method for entraining powder in an airflow
US9138167B1 (en) * 2009-09-25 2015-09-22 Krispin Johan Leydon Means for rendering key respiratory measurements accessible to mobile digital devices
US10869638B2 (en) 2009-09-25 2020-12-22 Krispin Johan Leydon Systems, devices and methods for rendering key respiratory measurements accessible to mobile digital devices
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
US9492625B2 (en) 2009-11-12 2016-11-15 Stc.Unm Dry powder inhaler with flutter dispersion member
BR112012011249A2 (pt) * 2009-11-13 2016-04-12 Schering Corp dispensador de pó, droga, e, produto de droga
GB2489383A (en) 2009-12-30 2012-09-26 Vijayan Thirumalai Anandampillai An improved dry powder inhaler
WO2011116293A2 (en) 2010-03-19 2011-09-22 Manta Devices, Llc Delivery device and related methods
USD635246S1 (en) * 2010-03-26 2011-03-29 Oriel Therapeutics, Inc. Dose disk for dry powder inhalers
JP6385673B2 (ja) 2010-06-21 2018-09-05 マンカインド コーポレイション 乾燥粉末薬物送達システム
AU2016222336B2 (en) * 2010-06-21 2018-09-13 Mannkind Corporation Dry powder drug delivery system and methods
ES2535979T3 (es) * 2010-07-21 2015-05-19 Astrazeneca Ab Inhalador
US9427533B2 (en) * 2010-11-29 2016-08-30 Sanofi-Aventis Deutschland Gmbh Medicated module for an inhaler
WO2012078804A1 (en) 2010-12-07 2012-06-14 Respira Therapeutics, Inc. Dry powder inhaler
CN102553038B (zh) * 2010-12-17 2014-07-02 陈庆堂 药粉吸嘴放置盒
GB201021881D0 (en) 2010-12-23 2011-02-02 Profibrix Bv Powder delivery device
WO2012135765A2 (en) 2011-04-01 2012-10-04 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US11103659B2 (en) 2011-07-06 2021-08-31 Manta Devices, Llc Delivery device and related methods
EP2731572B1 (en) * 2011-07-13 2021-04-07 Pharmaxis Ltd. Improvements relating to delivery devices
EP2731573B1 (en) * 2011-07-13 2019-10-30 Pharmaxis Ltd Improvements relating to delivery devices
DK2731571T3 (da) 2011-07-13 2020-02-17 Pharmaxis Ltd Forbedringer vedrørende leveringsanordninger
FR2979057B1 (fr) * 2011-08-19 2013-08-30 Valois Sas Dispositif d'inhalation de poudre.
FR2979058B1 (fr) * 2011-08-19 2013-08-30 Valois Sas Dispositif d'inhalation de poudre.
CN106730186B (zh) 2011-09-07 2020-06-09 康森特里克斯药物公司 干粉吸入装置
IN2014DN03093A (cg-RX-API-DMAC7.html) 2011-10-24 2015-05-15 Mannkind Corp
US10463815B2 (en) * 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
CA2865876A1 (en) 2012-03-07 2013-09-12 Advanced Inhalation Therapies (Ait) Ltd. Inhalation of nitric oxide for treating respiratory diseases
US9649454B2 (en) 2012-05-03 2017-05-16 Manta Devices, Llc Delivery device and related methods
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
US9839756B2 (en) 2012-11-27 2017-12-12 Resmed Limited Methods and apparatus for ionization therapy
ES2754388T3 (es) 2013-03-15 2020-04-17 Mannkind Corp Composiciones y métodos de dicetopiperazina microcristalina
AU2014290438B2 (en) 2013-07-18 2019-11-07 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
US20150020806A1 (en) * 2013-07-19 2015-01-22 Merck Sharp & Dohme Corp. Dry powder inhaler for delivering multipe agglomerate formulations
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
EP3110484A4 (en) * 2014-02-21 2018-02-14 Respira Therapeutics, Inc. Powder inhaler, system and methods
NO2709641T3 (cg-RX-API-DMAC7.html) 2014-03-10 2018-05-12
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US11147936B2 (en) 2014-05-02 2021-10-19 Manta Devices, Llc Dose delivery device with cover connected to dose chamber seal
PT3151893T (pt) * 2014-06-06 2018-05-18 Univ Groningen Um inalador de pó seco acionado por respiração
FR3025110B1 (fr) * 2014-09-02 2016-12-23 Univ Francois-Rabelais De Tours Dispositif de pulverisation nasale de produit fluide
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP3244952A4 (en) * 2015-01-14 2018-11-14 Respira Therapeutics, Inc. Powder dispersion methods and devices
EP3061501A1 (en) 2015-02-27 2016-08-31 Rottapharm Ltd. Composition for the treatment of acne
WO2016159889A1 (en) 2015-04-02 2016-10-06 Hill-Rom Services Pte. Ltd. Manifold for respiratory device
EP3117825A1 (en) 2015-07-16 2017-01-18 Rottapharm S.p.A. Oral formulation comprising berberine and morus alba extract
US20180164134A1 (en) * 2015-07-28 2018-06-14 Nazhiyuan Technology (Tangshan), LLC. Pneumatic sensor in electronic cigarette, device for processing airflow, and electronic cigarette
US10238821B2 (en) * 2016-10-11 2019-03-26 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
EP3600504B1 (en) 2017-03-28 2023-07-12 Concentrx Pharmaceuticals, Inc. Device for delivering dry powder medicaments
EP3840803A4 (en) * 2018-09-10 2022-05-18 Cipla Limited Single blister-strip based dispenser
DE102019219277A1 (de) * 2019-12-10 2021-06-10 Christian-Albrechts-Universität Zu Kiel Pulverförmige Formulierungen zur Inhalation
US11289063B1 (en) * 2020-07-17 2022-03-29 Whistle Shield LLC Hygienic whistle with enhanced sound-generating chamber
CN115105695B (zh) * 2022-06-02 2023-05-16 宁波职业技术学院 一种哮喘呼吸器及哮喘呼吸器的使用方法
WO2025252974A1 (en) * 2024-06-07 2025-12-11 Vectura Delivery Devices Limited Dry powder inhaler with a mixing element
CN118491823B (zh) * 2024-07-17 2024-09-13 安徽墙煌科技股份有限公司 一种铝单板喷涂工艺

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE483136A (cg-RX-API-DMAC7.html) 1947-09-04 1942-06-30
US2470296A (en) * 1948-04-30 1949-05-17 Abbott Lab Inhalator
US2534636A (en) 1949-02-12 1950-12-19 American Cyanamid Co Powder dispenser
US2816549A (en) 1956-11-16 1957-12-17 Isaac E Webster Dispensing device
US3362405A (en) * 1964-04-06 1968-01-09 Hamilton O. Hazel Method and apparatus for admixing gas with solid particles
US3809084A (en) 1970-02-16 1974-05-07 American Cyanamid Co Pressurized portable dispenser
SE367249B (cg-RX-API-DMAC7.html) * 1971-11-10 1974-05-20 T Griverus
YU41046B (en) * 1974-08-22 1986-10-31 Schering Ag Medicine inholating device
US3998226A (en) * 1975-09-22 1976-12-21 Edward G. Gomez Inhalation device for encapsulated concentrates
FR2352556A1 (fr) 1976-05-26 1977-12-23 Pasteur Institut Inhalateur de poudre
US4452239A (en) * 1980-03-25 1984-06-05 Hilal Malem Medical nebulizing apparatus
ES8206980A1 (es) * 1980-10-30 1982-09-01 Riker Laboratories Inc Un dispositivo para facilitar la inhalacion oral de medica- mentos en forma de polvo
US4509515A (en) 1982-02-23 1985-04-09 Fisons Plc Inhalation device
AT396333B (de) * 1982-10-08 1993-08-25 Glaxo Group Ltd Vorrichtung zur verabreichung von medikamenten an patienten, einrichtung mit mehreren solchen vorrichtungen und traeger mit medikamentbehaeltern hiefuer
AT384552B (de) 1985-08-01 1987-12-10 Hurka Wilhelm Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft
US4653494A (en) * 1985-12-20 1987-03-31 Ruderian Max J Nasal inhalation system
US4790305A (en) * 1986-06-23 1988-12-13 The Johns Hopkins University Medication delivery system
GB8909891D0 (en) 1989-04-28 1989-06-14 Riker Laboratories Inc Device
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
DE407028T1 (de) 1989-05-31 1994-03-17 Fisons Plc Medikament und Inhalationsvorrichtung dafür.
FI84698C (fi) 1989-06-16 1992-01-10 Huhtamaeki Oy Anordning foer finfoerdelning av agglomerat av en enkeldos av ett laekemedelpreparat i pulverform.
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.
US5042467A (en) * 1990-03-28 1991-08-27 Trudell Medical Medication inhaler with fitting having a sonic signalling device
IL111254A (en) * 1990-06-14 1998-10-30 Rhone Poulenc Rorer Ltd Powder inhalers
US5042472A (en) 1990-10-15 1991-08-27 Merck & Co., Inc. Powder inhaler device
EP0504459B1 (de) 1991-03-21 1996-06-05 PAUL RITZAU PARI-WERK GmbH Vernebler insbesondere zur Anwendung in Geräten für die Inhalationstherapie
US5797391A (en) 1991-03-28 1998-08-25 Rhone-Poulenc Rorer Limited Inhaler
US5492112A (en) 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
US5476093A (en) * 1992-02-14 1995-12-19 Huhtamaki Oy Device for more effective pulverization of a powdered inhalation medicament
EP0558879B1 (en) 1992-03-04 1997-05-14 Astra Aktiebolag Disposable inhaler
SE9302550D0 (sv) * 1993-07-30 1993-07-30 Ernst Hoerlin Powder inhaler
ES2122319T3 (es) * 1993-08-18 1998-12-16 Fisons Plc Inhalador con regulacion del caudal de aire.
DE4340768A1 (de) * 1993-11-30 1995-06-01 Bayer Ag Vorrichtung zum Inhalieren
DE59409856D1 (de) * 1994-05-19 2001-10-11 Pari Gmbh Vorrichtung zur Trocknung und Pufferung von Aerosolen
US5714007A (en) 1995-06-06 1998-02-03 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate
SE504458C2 (sv) 1995-06-21 1997-02-17 Lars Gunnar Nilsson Inhalator för elektrisk dosering av substanser
US5642727A (en) 1995-07-25 1997-07-01 David Sarnoff Research Center, Inc. Inhaler apparatus using a tribo-electric charging technique
US5669378A (en) * 1995-12-21 1997-09-23 Pera; Ivo Inhaling device
US6470884B2 (en) * 1996-01-29 2002-10-29 Aventis Pharma Limited Capsule opening arrangement for use in a powder inhaler
SE9600306D0 (sv) * 1996-01-29 1996-01-29 Ernst Hoerlin Capsule opening arrangement for use in a powder inhaler
GB9626233D0 (en) * 1996-12-18 1997-02-05 Chawla Brinda P S Medicament packaging and deliveery device
GB9720283D0 (en) 1997-09-25 1997-11-26 Norton Healthcare Ltd Inhaler spacer
US6073629A (en) * 1997-09-25 2000-06-13 Norton Healthcare Ltd. Inhaler spacer
US6125998A (en) * 1997-12-17 2000-10-03 Batista; Christina Whistle case
US6096368A (en) 1998-02-19 2000-08-01 Delsys Pharmaceutical Corporation Bead transporter chucks using repulsive field guidance and method
US6063194A (en) 1998-06-10 2000-05-16 Delsys Pharmaceutical Corporation Dry powder deposition apparatus
US6615826B1 (en) * 1999-02-26 2003-09-09 3M Innovative Properties Company Slow spray metered dose inhaler
GB9905538D0 (en) 1999-03-10 1999-05-05 Glaxo Group Ltd A device
US6427688B1 (en) * 2000-02-01 2002-08-06 Dura Pharmaceuticals, Icn. Dry powder inhaler
AU2001283546A1 (en) 2000-08-14 2002-02-25 Advanced Inhalation Research, Inc. Inhalation device and method
US6722364B2 (en) * 2001-01-12 2004-04-20 Becton, Dickinson And Company Medicament inhalation delivery devices and methods for using the same

Also Published As

Publication number Publication date
US7958890B2 (en) 2011-06-14
US20010027790A1 (en) 2001-10-11
EP1307256B1 (en) 2013-07-24
US20090084380A1 (en) 2009-04-02
US6715486B2 (en) 2004-04-06
CA2398815A1 (en) 2001-08-09
US20060005833A1 (en) 2006-01-12
AU2001233201A1 (en) 2001-08-14
JP4886143B2 (ja) 2012-02-29
WO2001056640A1 (en) 2001-08-09
JP2004502472A (ja) 2004-01-29
CA2398815C (en) 2012-04-17
EP1307256A4 (en) 2006-04-12
US20040163644A1 (en) 2004-08-26
US6427688B1 (en) 2002-08-06
WO2001056640A9 (en) 2002-10-24
EP1307256A1 (en) 2003-05-07
US6971384B2 (en) 2005-12-06

Similar Documents

Publication Publication Date Title
ES2432353T3 (es) Inhalador de polvo seco
RU2127612C1 (ru) Порошковый ингалятор
ES2383213T3 (es) Inhaladores de polvo seco
ES2638279T3 (es) Cartucho de dosis unitaria e inhalador de polvo seco
US11471623B2 (en) Powder dispersion methods and devices
JP3747076B2 (ja) 医薬吸入装置
RU2484852C2 (ru) Устройство и способ дезагрегации порошкообразного средства 854
ES2359576T3 (es) Inhalador de polvo.
ES2546025T3 (es) Inhalador
RU2089227C1 (ru) Устройство для эффективного распыления агломератов, образовавшихся в дозе порошкообразного медпрепарата, предназначенного для подачи в легкие пациента
ES2256293T3 (es) Inhaladores.
US20040159321A1 (en) Inhaler
CN106794325B (zh) 粉末吸入器、系统和方法
ES2772710T3 (es) Inhalador de polvo seco
US20250108180A1 (en) Powder dispersion methods and devices