ES2390243T3 - Agentes de unión biespecíficos específicos de especies cruzadas - Google Patents

Agentes de unión biespecíficos específicos de especies cruzadas Download PDF

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Publication number
ES2390243T3
ES2390243T3 ES08735000T ES08735000T ES2390243T3 ES 2390243 T3 ES2390243 T3 ES 2390243T3 ES 08735000 T ES08735000 T ES 08735000T ES 08735000 T ES08735000 T ES 08735000T ES 2390243 T3 ES2390243 T3 ES 2390243T3
Authority
ES
Spain
Prior art keywords
seq
cdr
represented
human
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08735000T
Other languages
English (en)
Spanish (es)
Inventor
Matthias Klinger
Tobias Raum
Doris Rau
Susanne Mangold
Roman Kischel
Ralf Lutterbüse
Patrick Hoffmann
Peter Kufer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Research Munich GmbH
Original Assignee
Micromet GmbH
Amgen Research Munich GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromet GmbH, Amgen Research Munich GmbH filed Critical Micromet GmbH
Priority claimed from PCT/EP2008/002663 external-priority patent/WO2008119566A2/en
Application granted granted Critical
Publication of ES2390243T3 publication Critical patent/ES2390243T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES08735000T 2007-04-03 2008-04-03 Agentes de unión biespecíficos específicos de especies cruzadas Active ES2390243T3 (es)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
EP07006988 2007-04-03
EP07006988 2007-04-03
EP07006990 2007-04-03
EP07006990 2007-04-03
US91366807P 2007-04-24 2007-04-24
US913668P 2007-04-24
EP07020640 2007-10-22
EP07020646 2007-10-22
EP07020646 2007-10-22
EP07020640 2007-10-22
EP07020641 2007-10-22
EP07020641 2007-10-22
EP08004741 2008-03-13
EP08004741 2008-03-13
PCT/EP2008/002663 WO2008119566A2 (en) 2007-04-03 2008-04-03 Cross-species-specific bispecific binders

Publications (1)

Publication Number Publication Date
ES2390243T3 true ES2390243T3 (es) 2012-11-07

Family

ID=42582614

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08735000T Active ES2390243T3 (es) 2007-04-03 2008-04-03 Agentes de unión biespecíficos específicos de especies cruzadas

Country Status (8)

Country Link
JP (1) JP2010524435A (cg-RX-API-DMAC7.html)
DK (1) DK2155788T3 (cg-RX-API-DMAC7.html)
ES (1) ES2390243T3 (cg-RX-API-DMAC7.html)
NZ (1) NZ580746A (cg-RX-API-DMAC7.html)
PT (1) PT2155788E (cg-RX-API-DMAC7.html)
RS (1) RS52492B (cg-RX-API-DMAC7.html)
RU (1) RU2535992C2 (cg-RX-API-DMAC7.html)
SI (1) SI2155788T1 (cg-RX-API-DMAC7.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2155788T3 (pl) * 2007-04-03 2013-02-28 Amgen Res Munich Gmbh Swoiste międzygatunkowe bispecyficzne czynniki wiążące
PT2520590T (pt) * 2007-04-03 2018-11-14 Amgen Res Munich Gmbh Domínio de ligação específico de espécies cruzadas
EP3974453A3 (en) * 2010-11-16 2022-08-03 Amgen Inc. Agents and methods for treating diseases that correlate with bcma expression
JP6400470B2 (ja) * 2011-05-16 2018-10-03 ジェネロン(シャンハイ)コーポレイション リミテッド 多重特異性Fab融合タンパク質および使用法
CN107722124A (zh) * 2011-05-21 2018-02-23 宏观基因有限公司 能够与人和非人cd3结合的cd3结合分子
CN106029696B (zh) 2013-12-17 2020-07-28 基因泰克公司 抗cd3抗体及使用方法
KR20170003591A (ko) * 2014-05-28 2017-01-09 에프. 호프만-라 로슈 아게 인간 및 사이노몰구스 cd3 엡실론에 결합하는 항체
AU2015292406B2 (en) * 2014-07-25 2021-03-11 Cytomx Therapeutics, Inc Anti-CD3 antibodies, activatable anti-CD3 antibodies, multispecific anti-CD3 antibodies, multispecific activatable anti-CD3 antibodies, and methods of using the same
JP6698065B2 (ja) * 2014-07-31 2020-05-27 アムゲン リサーチ (ミュンヘン) ゲーエムベーハーAMGEN Research(Munich)GmbH 組織分布が向上した二重特異性単鎖抗体コンストラクト
HK1250997A1 (zh) * 2015-05-01 2019-01-18 基因泰克公司 掩蔽抗cd3抗体和使用方法
AU2017233121B2 (en) 2016-03-15 2023-12-21 Itabmed (Hk) Limited Multispecific Fab fusion proteins and use thereof
US11466094B2 (en) 2016-11-15 2022-10-11 Genentech, Inc. Dosing for treatment with anti-CD20/anti-CD3 bispecific antibodies
US10426424B2 (en) 2017-11-21 2019-10-01 General Electric Company System and method for generating and performing imaging protocol simulations
CN118772288A (zh) 2018-02-08 2024-10-15 豪夫迈·罗氏有限公司 双特异性抗原结合分子和使用方法
EP3847196A4 (en) 2018-09-07 2023-01-04 ITabMed (HK) Limited BISPECIFIC ANTIGEN BINDING PROTEINS AND USES THEREOF
US20230067182A1 (en) * 2019-11-29 2023-03-02 Boe Technology Group Co., Ltd. Data Processing Device and Method, and Computer Readable Storage Medium
AR120741A1 (es) 2019-12-13 2022-03-16 Genentech Inc Anticuerpos anti-ly6g6d y métodos de uso
JP2022087602A (ja) * 2020-12-01 2022-06-13 株式会社バイオピーク 組換え大腸菌による有用タンパク質の生産性を向上するための培養方法
CA3218578A1 (en) 2021-05-14 2022-11-17 Carol Elaine O'hear Methods for treatment of cd20-positive proliferative disorder with mosunetuzumab and polatuzumab vedotin
CN115932808B (zh) * 2022-11-04 2025-05-27 四川九洲电器集团有限责任公司 一种基于多特征融合的被动声纳智能探测方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2179862C1 (ru) * 2000-12-26 2002-02-27 Общество с ограниченной ответственностью Научно-производственный центр "МедБиоСпектр" Лекарственное средство для предотвращения отторжения трансплантата, моноклональное антитело к cd3-антигену т-лимфоцитов человека, гибридома и способ лечения больных, имеющих реакцию острого отторжения трансплантата после пересадки почки
US7919089B2 (en) * 2003-05-31 2011-04-05 Micromet Ag Pharmaceutical composition comprising a bispecific antibody for EpCAM
US7235641B2 (en) * 2003-12-22 2007-06-26 Micromet Ag Bispecific antibodies
BRPI0511782B8 (pt) * 2004-06-03 2021-05-25 Novimmune Sa anticorpos anti-cd3, uso e método de produção dos mesmos, composição farmacêutica, molécula de ácido nucleico isolada e vetor
EP1933868A2 (en) * 2005-09-12 2008-06-25 NovImmune SA Anti-cd3 antibody formulations
WO2007042261A2 (en) * 2005-10-11 2007-04-19 Micromet Ag Compositions comprising cross-species-specific antibodies and uses thereof

Also Published As

Publication number Publication date
JP2010524435A (ja) 2010-07-22
PT2155788E (pt) 2012-09-25
NZ580746A (en) 2012-05-25
RS52492B (sr) 2013-02-28
SI2155788T1 (sl) 2012-11-30
DK2155788T3 (da) 2012-10-08
RU2009136913A (ru) 2011-06-20
RU2535992C2 (ru) 2014-12-20

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