ES2386554T3 - Polinucleótidos que codifican enzimas modificadoras de isoprenoides y procedimientos de uso de los mismos - Google Patents
Polinucleótidos que codifican enzimas modificadoras de isoprenoides y procedimientos de uso de los mismos Download PDFInfo
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- ES2386554T3 ES2386554T3 ES06785959T ES06785959T ES2386554T3 ES 2386554 T3 ES2386554 T3 ES 2386554T3 ES 06785959 T ES06785959 T ES 06785959T ES 06785959 T ES06785959 T ES 06785959T ES 2386554 T3 ES2386554 T3 ES 2386554T3
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- 235000021309 simple sugar Nutrition 0.000 description 1
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- 238000011282 treatment Methods 0.000 description 1
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- 229940038773 trisodium citrate Drugs 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
- C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
- C12N9/0042—NADPH-cytochrome P450 reductase (1.6.2.4)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y106/00—Oxidoreductases acting on NADH or NADPH (1.6)
- C12Y106/02—Oxidoreductases acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
- C12Y106/02004—NADPH-hemoprotein reductase (1.6.2.4), i.e. NADP-cytochrome P450-reductase
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Molecular Biology (AREA)
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- Medicinal Chemistry (AREA)
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- General Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
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| PCT/US2006/025572 WO2007005604A2 (en) | 2005-07-05 | 2006-06-29 | Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof |
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| ES2386554T3 true ES2386554T3 (es) | 2012-08-22 |
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| ES12158465.0T Active ES2621657T3 (es) | 2005-07-05 | 2006-06-29 | Polinucleótidos que codifican enzimas modificadoras de isoprenoides y procedimientos de uso de los mismos |
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| CA (1) | CA2613469C (enExample) |
| DK (1) | DK1919514T3 (enExample) |
| ES (2) | ES2386554T3 (enExample) |
| IL (1) | IL188376A (enExample) |
| MX (1) | MX2008000200A (enExample) |
| PL (1) | PL1919514T3 (enExample) |
| PT (1) | PT1919514E (enExample) |
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| SI (1) | SI1919514T1 (enExample) |
| WO (1) | WO2007005604A2 (enExample) |
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| ES2386359T3 (es) * | 2004-07-27 | 2012-08-17 | The Regents Of The University Of California | Células huésped modificadas genéticamente y uso de las mismas para producir compuestos isoprenoides |
| DK1919514T3 (da) * | 2005-07-05 | 2012-08-20 | Univ California | Polynucleotider kodende for isoprenoid-modificerende enzymer og fremgangsmåder til anvendelse deraf |
| CA2651747C (en) | 2006-05-26 | 2017-10-24 | Amyris Biotechnologies, Inc. | Production of isoprenoids |
| DK3020799T3 (da) | 2006-09-26 | 2020-09-21 | Amyris Biotechnologies Inc | Fremstilling af isoprenoider og isoprenoid-prækursorer |
| CA2692893C (en) | 2007-06-01 | 2015-06-23 | The Scripps Research Institute | High throughput screening of genetically modified photosynthetic organisms |
| NZ583620A (en) | 2007-09-11 | 2012-08-31 | Sapphire Energy Inc | Methods of producing organic fuel products with photosynthetic organisms |
| EP2444415A1 (en) * | 2010-10-20 | 2012-04-25 | Genoplante-Valor | 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis |
| MX352318B (es) * | 2011-11-01 | 2017-11-21 | Firmenich & Cie | Citocromo p450 y su uso para oxidacion enzimatica de terpenos. |
| JP5827601B2 (ja) * | 2012-07-04 | 2015-12-02 | 住友ゴム工業株式会社 | 特定の蛋白質の発現を光応答転写因子により調整する方法、光応答転写因子をコードする遺伝子が導入されたイソプレノイド産生植物、及び該イソプレノイド産生植物を用いたポリイソプレノイドの製造方法 |
| CA2880929A1 (en) * | 2012-09-07 | 2014-03-13 | Sanofi | Fusion proteins for treating a metabolic syndrome |
| PL224377B1 (pl) * | 2012-11-02 | 2016-12-30 | Inst Biochemii I Biofizyki Polskiej Akademii Nauk | Szczep Trichoderma atroviride, sposób otrzymywania i zastosowanie szczepu Trichoderma atroviride jako środka biobójczego |
| CA2924541A1 (en) * | 2013-09-19 | 2015-03-26 | Firmenich Sa | Method for producing fragrant alcohols |
| JP6475336B2 (ja) * | 2014-08-21 | 2019-02-27 | チュン−アン ユニヴァーシティ インダストリー−アカデミー コーポレーション ファウンデーションＣｈｕｎｇ−Ａｎｇ Ｕｎｉｖｅｒｓｉｔｙ Ｉｎｄｕｓｔｒｙ−Ａｃａｄｅｍｙ Ｃｏｏｐｅｒａｔｉｏｎ Ｆｏｕｎｄａｔｉｏｎ | ｒＤＮＡ ＮＴＳ基盤の遺伝子多重挿入カセットセット、及びそれを用いたＧＲＡＳ等級の組換え酵母菌株 |
| EP3283615A4 (en) * | 2015-04-15 | 2018-09-05 | William Marsh Rice University | Iterative platform for the synthesis of alpha functionalized products |
| US11697830B2 (en) * | 2015-04-15 | 2023-07-11 | Ramon Gonzalez | Iterative platform for the synthesis of alpha functionalized products |
| CN105177007B (zh) * | 2015-10-30 | 2017-11-10 | 上海交通大学 | 一种调控基因在非分泌型腺毛中表达的启动子及其应用 |
| CN105274109B (zh) * | 2015-10-30 | 2017-12-29 | 上海交通大学 | 一种调控基因在非分泌型腺毛中表达的启动子及其应用 |
| CN105483236A (zh) * | 2015-12-26 | 2016-04-13 | 吉林省农业科学院 | 转基因植物中cry1C基因的LAMP检测引物组、试剂盒及检测方法 |
| CN105567685B (zh) * | 2016-01-18 | 2018-07-13 | 上海交通大学 | AaPDR3基因启动子及其应用 |
| CA3036968A1 (en) | 2016-09-20 | 2018-03-29 | 22Nd Century Limited, Llc | Trichome specific promoters for the manipulation of cannabinoids and other compounds in glandular trichomes |
| WO2018111194A1 (en) * | 2016-12-16 | 2018-06-21 | Temasek Life Sciences Laboratory Limited | Targets for improving terpene production in rhodosporidium toruloides |
| AU2018239671B2 (en) | 2017-03-24 | 2024-08-15 | Trait Biosciences, Inc. | High level In vivo biosynthesis and isolation of water-soluble cannabinoids in plant systems |
| US11946059B2 (en) | 2017-07-11 | 2024-04-02 | Trait Biosciences, Inc. | In vivo generation of water-soluble cannabinoids in plant cell suspension cultures |
| EP3730145A1 (en) | 2017-07-11 | 2020-10-28 | Trait Biosciences, Inc. | Generation of water-soluble cannabinoid compounds in yeast and plant cell suspension cultures and compositions of matter |
| US11905543B2 (en) | 2017-07-11 | 2024-02-20 | Trait Biosceinces, Inc. | In vivo generation of water-soluble acetylated cannabinoid glycoside compounds in plant cell suspension cultures |
| EP3877519B1 (en) | 2018-11-09 | 2026-03-11 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
| MX2022009071A (es) * | 2020-01-23 | 2022-08-15 | Amyris Inc | Variantes de amorfa-4, 11-dieno 12-monooxigenasa y usos de las mismas. |
| CN111621508B (zh) * | 2020-06-11 | 2022-07-01 | 云南中烟工业有限责任公司 | 烟草萜类合成酶NtTPS7基因及其载体与应用 |
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| US5451513A (en) | 1990-05-01 | 1995-09-19 | The State University of New Jersey Rutgers | Method for stably transforming plastids of multicellular plants |
| EP0640136B1 (en) * | 1992-03-27 | 2003-05-07 | INTERNATIONAL FLOWER DEVELOPMENTS Pty. Ltd. | Genetic sequences encoding flavonoid pathway enzymes with flavonoid 3'-hydroxylase activity and uses thereof |
| FR2689905B1 (fr) * | 1992-04-13 | 1995-07-13 | Orsan | Procede de clonage d'une sequence d'adn codant pour une nadph cytochrome p450 reductase et sequences d'adn codant pour une nadph-cytochrome p450 reductase, notamment de plantes. |
| US5576198A (en) | 1993-12-14 | 1996-11-19 | Calgene, Inc. | Controlled expression of transgenic constructs in plant plastids |
| US5545818A (en) | 1994-03-11 | 1996-08-13 | Calgene Inc. | Expression of Bacillus thuringiensis cry proteins in plant plastids |
| US5545817A (en) | 1994-03-11 | 1996-08-13 | Calgene, Inc. | Enhanced expression in a plant plastid |
| DE69526377T2 (de) | 1994-12-09 | 2002-11-07 | Microscience Ltd | Virulenzgene in der VGC2-Region von Salmonella |
| AR011182A1 (es) * | 1997-03-07 | 2000-08-02 | Syngenta Participations Ag | Molecula de adn, monooxigenasa de citocromo p450, codificada por dicha molecula, un metodo para el aislamiento de una molecula de adnc, un metodo parala produccion de una monooxigenasa de citocromo p450 recombinante purificada, una planta transgenica, un metodo para obtener dicha planta, el uso de d |
| US6900012B1 (en) | 1997-06-03 | 2005-05-31 | The University Of Chicago | Plant artificial chromosome compositions and methods |
| US6083731A (en) * | 1997-06-24 | 2000-07-04 | Washington State University Research Foundation | Recombinant materials and methods for the production of limonene hydroxylases |
| US6080849A (en) | 1997-09-10 | 2000-06-27 | Vion Pharmaceuticals, Inc. | Genetically modified tumor-targeted bacteria with reduced virulence |
| EP0982404A1 (en) * | 1998-08-27 | 2000-03-01 | Wallaart, Thorvald Eelco | DNA encoding amorpha-4,11-diene synthase |
| US6645747B1 (en) | 1999-09-21 | 2003-11-11 | E. I. Du Pont De Nemours And Company | Cis-prenyltransferases from plants |
| US6369212B1 (en) | 2000-02-07 | 2002-04-09 | Korea Kumbo Petrochemical Co., Ltd. | Cytochrome P450 gene highly expressed in the incompatible interaction |
| EP1354955A4 (en) * | 2000-12-28 | 2005-01-05 | Toyota Motor Co Ltd | PROCESS FOR PREPARING PRENYL ALCOHOL |
| ATE513046T1 (de) * | 2001-03-09 | 2011-07-15 | Univ Kentucky Res Found | Cytochrom p450s und verwendungen davon |
| GB0105924D0 (en) | 2001-03-09 | 2001-04-25 | Microscience Ltd | Promoter |
| AUPR446701A0 (en) * | 2001-04-18 | 2001-05-17 | Gene Stream Pty Ltd | Transgenic mammals for pharmacological and toxicological studies |
| CN1589327A (zh) | 2001-09-17 | 2005-03-02 | 植物研究国际公司 | 用于生物转化的植物酶 |
| US20040162420A1 (en) | 2002-10-16 | 2004-08-19 | U.S. Smokeless Tobacco Company | Cloning of cytochrome p450 genes from nicotiana |
| US7172886B2 (en) | 2001-12-06 | 2007-02-06 | The Regents Of The University Of California | Biosynthesis of isopentenyl pyrophosphate |
| US7192751B2 (en) | 2001-12-06 | 2007-03-20 | The Regents Of The University Of California | Biosynthesis of amorpha-4,11-diene |
| US6733996B2 (en) | 2002-08-26 | 2004-05-11 | Trustees Of Dartmouth College | Methods for regulating gene expression using light |
| DK1919514T3 (da) * | 2005-07-05 | 2012-08-20 | Univ California | Polynucleotider kodende for isoprenoid-modificerende enzymer og fremgangsmåder til anvendelse deraf |
| CA2630305A1 (en) * | 2005-10-24 | 2007-05-03 | National Research Council Of Canada | A novel gene encoding amorphadiene hydroxylase and a process to produce artemisinic alcohol therewith |
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