AP3827A - Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof - Google Patents

Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof

Info

Publication number
AP3827A
AP3827A AP2013006962A AP2013006962A AP3827A AP 3827 A AP3827 A AP 3827A AP 2013006962 A AP2013006962 A AP 2013006962A AP 2013006962 A AP2013006962 A AP 2013006962A AP 3827 A AP3827 A AP 3827A
Authority
AP
ARIPO
Prior art keywords
methods
polynucleotides encoding
modifying enzymes
isoprenoid modifying
encoding isoprenoid
Prior art date
Application number
AP2013006962A
Other languages
English (en)
Other versions
AP2013006962A0 (en
Inventor
Timothy Ham
Kimberly Ho
Karyn Newman
Rachel Eachus
Dae-Kyun Ro
Eric M Paradise
Mario Ouellet
Jay D Keasling
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of AP2013006962A0 publication Critical patent/AP2013006962A0/xx
Application granted granted Critical
Publication of AP3827A publication Critical patent/AP3827A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12N9/0042NADPH-cytochrome P450 reductase (1.6.2.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y106/00Oxidoreductases acting on NADH or NADPH (1.6)
    • C12Y106/02Oxidoreductases acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12Y106/02004NADPH-hemoprotein reductase (1.6.2.4), i.e. NADP-cytochrome P450-reductase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
AP2013006962A 2005-07-05 2006-06-29 Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof AP3827A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69706705P 2005-07-05 2005-07-05
PCT/US2006/025572 WO2007005604A2 (en) 2005-07-05 2006-06-29 Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof

Publications (2)

Publication Number Publication Date
AP2013006962A0 AP2013006962A0 (en) 2013-07-31
AP3827A true AP3827A (en) 2016-09-30

Family

ID=37605033

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2013006962A AP3827A (en) 2005-07-05 2006-06-29 Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof

Country Status (18)

Country Link
US (2) US8163980B2 (enExample)
EP (2) EP2489672B1 (enExample)
JP (1) JP2009504138A (enExample)
KR (2) KR101444090B1 (enExample)
CN (4) CN106939323B (enExample)
AP (1) AP3827A (enExample)
BR (1) BRPI0612411B8 (enExample)
CA (1) CA2613469C (enExample)
DK (1) DK1919514T3 (enExample)
ES (2) ES2386554T3 (enExample)
IL (1) IL188376A (enExample)
MX (1) MX2008000200A (enExample)
PL (1) PL1919514T3 (enExample)
PT (1) PT1919514E (enExample)
SG (1) SG176459A1 (enExample)
SI (1) SI1919514T1 (enExample)
WO (1) WO2007005604A2 (enExample)
ZA (1) ZA200800889B (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006014837A1 (en) 2004-07-27 2006-02-09 The Regents Of The University Of California Genetically modified host cells and use of same for producing isoprenoid compounds
US8163980B2 (en) * 2005-07-05 2012-04-24 The Regents Of The University Of California Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof
EP3031924A1 (en) 2006-05-26 2016-06-15 Amyris, Inc. Production of isoprenoids
DK3020799T3 (da) 2006-09-26 2020-09-21 Amyris Biotechnologies Inc Fremstilling af isoprenoider og isoprenoid-prækursorer
CN101835901B (zh) 2007-06-01 2013-03-06 蓝宝石能源公司 遗传修饰的光合生物的高通量筛选
JP2010539294A (ja) 2007-09-11 2010-12-16 サファイア エナジー,インコーポレイティド 光合成生物を用いた有機製品の製造方法ならびにその製品および組成物
EP2444415A1 (en) * 2010-10-20 2012-04-25 Genoplante-Valor 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis
PL2773751T3 (pl) * 2011-11-01 2017-08-31 Firmenich Sa Cytochrom 450 i jego zastosowanie w enzymatycznym utlenianiu terpenów
JP5827601B2 (ja) * 2012-07-04 2015-12-02 住友ゴム工業株式会社 特定の蛋白質の発現を光応答転写因子により調整する方法、光応答転写因子をコードする遺伝子が導入されたイソプレノイド産生植物、及び該イソプレノイド産生植物を用いたポリイソプレノイドの製造方法
SG11201500682WA (en) * 2012-09-07 2015-02-27 Sanofi Sa Fusion proteins for treating a metabolic syndrome
PL224377B1 (pl) * 2012-11-02 2016-12-30 Inst Biochemii I Biofizyki Polskiej Akademii Nauk Szczep Trichoderma atroviride, sposób otrzymywania i zastosowanie szczepu Trichoderma atroviride jako środka biobójczego
US9909145B2 (en) * 2013-09-19 2018-03-06 Firmenich Sa Method for producing fragrant alcohols
EP3184639B1 (en) * 2014-08-21 2019-06-12 Chung-Ang University Industry-Academy Cooperation Foundation Rdna nts based gene multiple insertion cassette set and gras-grade recombinant yeast strain
WO2016168681A1 (en) * 2015-04-15 2016-10-20 William Marsh Rice University Iterative platform for the synthesis of alpha functionalized products
US11697830B2 (en) * 2015-04-15 2023-07-11 Ramon Gonzalez Iterative platform for the synthesis of alpha functionalized products
CN105274109B (zh) * 2015-10-30 2017-12-29 上海交通大学 一种调控基因在非分泌型腺毛中表达的启动子及其应用
CN105177007B (zh) * 2015-10-30 2017-11-10 上海交通大学 一种调控基因在非分泌型腺毛中表达的启动子及其应用
CN105483236A (zh) * 2015-12-26 2016-04-13 吉林省农业科学院 转基因植物中cry1C基因的LAMP检测引物组、试剂盒及检测方法
CN105567685B (zh) * 2016-01-18 2018-07-13 上海交通大学 AaPDR3基因启动子及其应用
ES2940673T3 (es) 2016-09-20 2023-05-10 22Nd Century Ltd Llc Promotores específicos de tricomas para la manipulación de cannabinoides y otros compuestos en tricomas glandulares
WO2018111194A1 (en) * 2016-12-16 2018-06-21 Temasek Life Sciences Laboratory Limited Targets for improving terpene production in rhodosporidium toruloides
WO2018176055A2 (en) 2017-03-24 2018-09-27 Trait Biosciences, Inc. High level in vivo biosynthesis and isolation of water-soluble cannabinoids in plant systems
US11905543B2 (en) 2017-07-11 2024-02-20 Trait Biosceinces, Inc. In vivo generation of water-soluble acetylated cannabinoid glycoside compounds in plant cell suspension cultures
AU2018301674B2 (en) 2017-07-11 2024-03-28 Trait Biosciences, Inc. Generation of water-soluble cannabinoid compounds in yeast and plant cell suspension cultures and compositions of matter
US11946059B2 (en) 2017-07-11 2024-04-02 Trait Biosciences, Inc. In vivo generation of water-soluble cannabinoids in plant cell suspension cultures
CA3118924A1 (en) 2018-11-09 2020-05-14 Ginkgo Bioworks, Inc. Biosynthesis of mogrosides
BR112022013523A2 (pt) * 2020-01-23 2022-09-13 Amyris Inc Polipeptídeo da amorfa-4,11-dieno 12-mono-oxigenase variante, ácido nucleico, célula hospedeira e método para gerar uma variante
CN111621508B (zh) * 2020-06-11 2022-07-01 云南中烟工业有限责任公司 烟草萜类合成酶NtTPS7基因及其载体与应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
DE69332951T2 (de) * 1992-03-27 2004-02-26 International Flower Developments Pty. Ltd., Collingwood Gensequenzen kodierend für enzyme des flavonoid stoffwechselweges mit einer flavonoid 3'-hydroxylase aktivität une ihre anwendungen
FR2689905B1 (fr) * 1992-04-13 1995-07-13 Orsan Procede de clonage d'une sequence d'adn codant pour une nadph cytochrome p450 reductase et sequences d'adn codant pour une nadph-cytochrome p450 reductase, notamment de plantes.
US5576198A (en) 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
US5545818A (en) 1994-03-11 1996-08-13 Calgene Inc. Expression of Bacillus thuringiensis cry proteins in plant plastids
US5545817A (en) 1994-03-11 1996-08-13 Calgene, Inc. Enhanced expression in a plant plastid
WO1996017951A2 (en) 1994-12-09 1996-06-13 Rpms Technology Limited Identification of genes responsible for in vivo survival of microorganisms
TR199902183T2 (xx) * 1997-03-07 1999-12-21 Novartis Ag Sitokrom P450 monoksigenazlar
US6900012B1 (en) 1997-06-03 2005-05-31 The University Of Chicago Plant artificial chromosome compositions and methods
US6083731A (en) * 1997-06-24 2000-07-04 Washington State University Research Foundation Recombinant materials and methods for the production of limonene hydroxylases
US6080849A (en) 1997-09-10 2000-06-27 Vion Pharmaceuticals, Inc. Genetically modified tumor-targeted bacteria with reduced virulence
EP0982404A1 (en) * 1998-08-27 2000-03-01 Wallaart, Thorvald Eelco DNA encoding amorpha-4,11-diene synthase
US6645747B1 (en) 1999-09-21 2003-11-11 E. I. Du Pont De Nemours And Company Cis-prenyltransferases from plants
US6369212B1 (en) 2000-02-07 2002-04-09 Korea Kumbo Petrochemical Co., Ltd. Cytochrome P450 gene highly expressed in the incompatible interaction
CA2433529A1 (en) * 2000-12-28 2002-07-11 Toyota Jidosha Kabushiki Kaisha Process for producing prenyl alcohol
GB0105924D0 (en) 2001-03-09 2001-04-25 Microscience Ltd Promoter
JP2004532014A (ja) * 2001-03-09 2004-10-21 ユニバーシティ・オブ・ケンタッキー・リサーチ・ファウンデーション チトクロームp450類及びその使用
AUPR446701A0 (en) * 2001-04-18 2001-05-17 Gene Stream Pty Ltd Transgenic mammals for pharmacological and toxicological studies
WO2003025193A1 (en) 2001-09-17 2003-03-27 Plant Research International B.V. Plant enzymes for bioconversion
US20040162420A1 (en) 2002-10-16 2004-08-19 U.S. Smokeless Tobacco Company Cloning of cytochrome p450 genes from nicotiana
US7172886B2 (en) 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
US7192751B2 (en) 2001-12-06 2007-03-20 The Regents Of The University Of California Biosynthesis of amorpha-4,11-diene
US6733996B2 (en) 2002-08-26 2004-05-11 Trustees Of Dartmouth College Methods for regulating gene expression using light
US8163980B2 (en) * 2005-07-05 2012-04-24 The Regents Of The University Of California Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof
CA2630305A1 (en) * 2005-10-24 2007-05-03 National Research Council Of Canada A novel gene encoding amorphadiene hydroxylase and a process to produce artemisinic alcohol therewith

Also Published As

Publication number Publication date
CN101495499A (zh) 2009-07-29
KR101444090B1 (ko) 2014-09-26
CA2613469C (en) 2014-08-12
WO2007005604A3 (en) 2008-12-31
SI1919514T1 (sl) 2012-08-31
BRPI0612411B1 (pt) 2020-05-05
ES2621657T3 (es) 2017-07-04
KR20080031054A (ko) 2008-04-07
EP2489672A2 (en) 2012-08-22
AP2013006962A0 (en) 2013-07-31
KR101487304B1 (ko) 2015-01-28
PT1919514E (pt) 2012-08-16
HK1134495A1 (en) 2010-04-30
CA2613469A1 (en) 2007-01-11
ZA200800889B (en) 2009-09-30
EP2489672B1 (en) 2017-01-18
CN105950667A (zh) 2016-09-21
JP2009504138A (ja) 2009-02-05
MX2008000200A (es) 2008-04-07
US8163980B2 (en) 2012-04-24
EP2489672A3 (en) 2013-01-09
US20120288905A1 (en) 2012-11-15
US20100218283A1 (en) 2010-08-26
IL188376A (en) 2012-12-31
BRPI0612411A2 (pt) 2010-11-09
IL188376A0 (en) 2008-04-13
CN103667370A (zh) 2014-03-26
WO2007005604A2 (en) 2007-01-11
US8759632B2 (en) 2014-06-24
SG176459A1 (en) 2011-12-29
BRPI0612411B8 (pt) 2021-05-25
ES2386554T3 (es) 2012-08-22
CN101495499B (zh) 2013-09-04
CN106939323B (zh) 2021-07-13
DK1919514T3 (da) 2012-08-20
EP1919514B1 (en) 2012-05-16
BRPI0612411A8 (pt) 2017-12-26
CN103667370B (zh) 2016-08-10
CN106939323A (zh) 2017-07-11
EP1919514A2 (en) 2008-05-14
PL1919514T3 (pl) 2012-10-31
EP1919514A4 (en) 2009-12-02
KR20130054468A (ko) 2013-05-24

Similar Documents

Publication Publication Date Title
IL188376A0 (en) Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof
EP1874759A4 (en) C-MET MODULATORS MODULATORS AND METHODS OF USE
GB2429023B (en) Connector assembly and method of use
ZA200710173B (en) Tygecycline and methods of preparing 9-nitrominocycline
ZA200802501B (en) Indenoisoquinolinone analogs and methods of use thereof
EP1864488A4 (en) METHOD AND SYSTEM FOR PROVIDING A USER INTERFACE
IL186490A0 (en) Multicyclic compounds and methods of their use
IL213843A0 (en) 4-aminotetracyclines and methods of use thereof
IL188078A0 (en) Nano-ionic liquids and methods of use
IL176958A0 (en) Compounds and methods of use
IL191139A0 (en) Novel pyridopyrazines and their use as modulators of kinases
IL186342A0 (en) Spirocyclic heterocycic derivaives and methods of their use
IL185309A0 (en) Isoqunoline compounds and methods of use thereof
IL185757A0 (en) Methods of decreasing calcifcation
EP1874731A4 (en) CHINOBENZOXAZINANALOGA AND METHOD FOR THE APPLICATION
IL185259A0 (en) Tetracyclic amino and carboxamido compounds and methods of use thereof
EP1888779A4 (en) METHOD FOR THE ANALYSIS OF POLYMORPHISMS AND USES THEREOF
GB2428890B (en) Fluid-based switch, and method of making same
EP1934140A4 (en) SILICA NANOBOITIERS AND METHODS OF ELEMENTS AND USES THEREOF
ZA200803864B (en) Novel pyridopyrazines and their use as modulators of kinases
EP1915443A4 (en) IMMOBILIZED ENZYMES AND USE METHOD THEREFOR
GB0404487D0 (en) Use of enzyme
GB0520930D0 (en) Composition and method of use
AP2741A (en) Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof
IL178683A0 (en) Methods of diminishing co-abuse potenitial