JP2009504138A - イソプレノイド修飾酵素をコードするポリヌクレオチド、およびその使用方法 - Google Patents

イソプレノイド修飾酵素をコードするポリヌクレオチド、およびその使用方法 Download PDF

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JP2009504138A
JP2009504138A JP2008519611A JP2008519611A JP2009504138A JP 2009504138 A JP2009504138 A JP 2009504138A JP 2008519611 A JP2008519611 A JP 2008519611A JP 2008519611 A JP2008519611 A JP 2008519611A JP 2009504138 A JP2009504138 A JP 2009504138A
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nucleotide sequence
isoprenoid
host cell
nucleic acid
terpene
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JP2009504138A5 (enExample
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デ−ギョン ロ
カーリン ニューマン
エリック エム． パラダイス
ジェイ ディー． キースリング
マリオ ウェレット
レイチェル エアチュス
キンバリー ホー
ティモシー ハム
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University of California
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University of California
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12N9/0042—NADPH-cytochrome P450 reductase (1.6.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y106/00—Oxidoreductases acting on NADH or NADPH (1.6)
    • C12Y106/02—Oxidoreductases acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
    • C12Y106/02004—NADPH-hemoprotein reductase (1.6.2.4), i.e. NADP-cytochrome P450-reductase

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
JP2008519611A 2005-07-05 2006-06-29 イソプレノイド修飾酵素をコードするポリヌクレオチド、およびその使用方法 Withdrawn JP2009504138A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69706705P 2005-07-05 2005-07-05
PCT/US2006/025572 WO2007005604A2 (en) 2005-07-05 2006-06-29 Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof

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JP2009504138A true JP2009504138A (ja) 2009-02-05
JP2009504138A5 JP2009504138A5 (enExample) 2009-09-10

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JP2008519611A Withdrawn JP2009504138A (ja) 2005-07-05 2006-06-29 イソプレノイド修飾酵素をコードするポリヌクレオチド、およびその使用方法

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US (2) US8163980B2 (enExample)
EP (2) EP2489672B1 (enExample)
JP (1) JP2009504138A (enExample)
KR (2) KR101444090B1 (enExample)
CN (4) CN101495499B (enExample)
AP (1) AP3827A (enExample)
BR (1) BRPI0612411B8 (enExample)
CA (1) CA2613469C (enExample)
DK (1) DK1919514T3 (enExample)
ES (2) ES2386554T3 (enExample)
IL (1) IL188376A (enExample)
MX (1) MX2008000200A (enExample)
PL (1) PL1919514T3 (enExample)
PT (1) PT1919514E (enExample)
SG (1) SG176459A1 (enExample)
SI (1) SI1919514T1 (enExample)
WO (1) WO2007005604A2 (enExample)
ZA (1) ZA200800889B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014007285A1 (ja) * 2012-07-04 2014-01-09 住友ゴム工業株式会社 特定の蛋白質の発現を光応答転写因子により調整する方法、光応答転写因子をコードする遺伝子が導入されたイソプレノイド産生植物、及び該イソプレノイド産生植物を用いたポリイソプレノイドの製造方法
JP2014532418A (ja) * 2011-11-01 2014-12-08 フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ シトクロムｐ４５０及びテルペンの酵素的酸化のためのそれらの使用

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DK1919514T3 (da) * 2005-07-05 2012-08-20 Univ California Polynucleotider kodende for isoprenoid-modificerende enzymer og fremgangsmåder til anvendelse deraf
CA2651747C (en) 2006-05-26 2017-10-24 Amyris Biotechnologies, Inc. Production of isoprenoids
DK3020799T3 (da) 2006-09-26 2020-09-21 Amyris Biotechnologies Inc Fremstilling af isoprenoider og isoprenoid-prækursorer
CA2692893C (en) 2007-06-01 2015-06-23 The Scripps Research Institute High throughput screening of genetically modified photosynthetic organisms
NZ583620A (en) 2007-09-11 2012-08-31 Sapphire Energy Inc Methods of producing organic fuel products with photosynthetic organisms
EP2444415A1 (en) * 2010-10-20 2012-04-25 Genoplante-Valor 1-Deoxy-D-xylulose 5-phosphate synthase alleles responsible for enhanced terpene biosynthesis
CA2880929A1 (en) * 2012-09-07 2014-03-13 Sanofi Fusion proteins for treating a metabolic syndrome
PL224377B1 (pl) * 2012-11-02 2016-12-30 Inst Biochemii I Biofizyki Polskiej Akademii Nauk Szczep Trichoderma atroviride, sposób otrzymywania i zastosowanie szczepu Trichoderma atroviride jako środka biobójczego
CA2924541A1 (en) * 2013-09-19 2015-03-26 Firmenich Sa Method for producing fragrant alcohols
JP6475336B2 (ja) * 2014-08-21 2019-02-27 チュン−アン ユニヴァーシティ インダストリー−アカデミー コーポレーション ファウンデーションＣｈｕｎｇ−Ａｎｇ Ｕｎｉｖｅｒｓｉｔｙ Ｉｎｄｕｓｔｒｙ−Ａｃａｄｅｍｙ Ｃｏｏｐｅｒａｔｉｏｎ Ｆｏｕｎｄａｔｉｏｎ ｒＤＮＡ ＮＴＳ基盤の遺伝子多重挿入カセットセット、及びそれを用いたＧＲＡＳ等級の組換え酵母菌株
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US11697830B2 (en) * 2015-04-15 2023-07-11 Ramon Gonzalez Iterative platform for the synthesis of alpha functionalized products
CN105177007B (zh) * 2015-10-30 2017-11-10 上海交通大学 一种调控基因在非分泌型腺毛中表达的启动子及其应用
CN105274109B (zh) * 2015-10-30 2017-12-29 上海交通大学 一种调控基因在非分泌型腺毛中表达的启动子及其应用
CN105483236A (zh) * 2015-12-26 2016-04-13 吉林省农业科学院 转基因植物中cry1C基因的LAMP检测引物组、试剂盒及检测方法
CN105567685B (zh) * 2016-01-18 2018-07-13 上海交通大学 AaPDR3基因启动子及其应用
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AU2018239671B2 (en) 2017-03-24 2024-08-15 Trait Biosciences, Inc. High level In vivo biosynthesis and isolation of water-soluble cannabinoids in plant systems
US11946059B2 (en) 2017-07-11 2024-04-02 Trait Biosciences, Inc. In vivo generation of water-soluble cannabinoids in plant cell suspension cultures
EP3730145A1 (en) 2017-07-11 2020-10-28 Trait Biosciences, Inc. Generation of water-soluble cannabinoid compounds in yeast and plant cell suspension cultures and compositions of matter
US11905543B2 (en) 2017-07-11 2024-02-20 Trait Biosceinces, Inc. In vivo generation of water-soluble acetylated cannabinoid glycoside compounds in plant cell suspension cultures
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MX2022009071A (es) * 2020-01-23 2022-08-15 Amyris Inc Variantes de amorfa-4, 11-dieno 12-monooxigenasa y usos de las mismas.
CN111621508B (zh) * 2020-06-11 2022-07-01 云南中烟工业有限责任公司 烟草萜类合成酶NtTPS7基因及其载体与应用

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014532418A (ja) * 2011-11-01 2014-12-08 フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ シトクロムｐ４５０及びテルペンの酵素的酸化のためのそれらの使用
JP2017042161A (ja) * 2011-11-01 2017-03-02 フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ シトクロムｐ４５０、及びテルペンの酵素的酸化のためのそれらの使用
WO2014007285A1 (ja) * 2012-07-04 2014-01-09 住友ゴム工業株式会社 特定の蛋白質の発現を光応答転写因子により調整する方法、光応答転写因子をコードする遺伝子が導入されたイソプレノイド産生植物、及び該イソプレノイド産生植物を用いたポリイソプレノイドの製造方法
JP2014011972A (ja) * 2012-07-04 2014-01-23 Sumitomo Rubber Ind Ltd 特定の蛋白質の発現を光応答転写因子により調整する方法、光応答転写因子をコードする遺伝子が導入されたイソプレノイド産生植物、及び該イソプレノイド産生植物を用いたポリイソプレノイドの製造方法
US9834779B2 (en) 2012-07-04 2017-12-05 Sumitomo Rubber Industries, Ltd. Method for regulating expression of specific protein using photoresponsive transcriptional factor, isoprenoid-producing plant having gene encoding photoresponsive transcriptional factor introduced thereinto, and method for producing polyisoprenoid using said isoprenoid-producing plant

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EP2489672A2 (en) 2012-08-22
WO2007005604A2 (en) 2007-01-11
SG176459A1 (en) 2011-12-29
CN103667370B (zh) 2016-08-10
CN103667370A (zh) 2014-03-26
EP1919514B1 (en) 2012-05-16
CN106939323A (zh) 2017-07-11
KR20130054468A (ko) 2013-05-24
EP1919514A2 (en) 2008-05-14
ES2621657T3 (es) 2017-07-04
EP1919514A4 (en) 2009-12-02
PL1919514T3 (pl) 2012-10-31
ZA200800889B (en) 2009-09-30
SI1919514T1 (sl) 2012-08-31
BRPI0612411B8 (pt) 2021-05-25
BRPI0612411B1 (pt) 2020-05-05
MX2008000200A (es) 2008-04-07
US8759632B2 (en) 2014-06-24
US20120288905A1 (en) 2012-11-15
CN105950667A (zh) 2016-09-21
CN101495499B (zh) 2013-09-04
KR101444090B1 (ko) 2014-09-26
PT1919514E (pt) 2012-08-16
AP3827A (en) 2016-09-30
CN106939323B (zh) 2021-07-13
ES2386554T3 (es) 2012-08-22
CA2613469A1 (en) 2007-01-11
AP2013006962A0 (en) 2013-07-31
IL188376A0 (en) 2008-04-13
EP2489672A3 (en) 2013-01-09
CN101495499A (zh) 2009-07-29
KR20080031054A (ko) 2008-04-07
US20100218283A1 (en) 2010-08-26
DK1919514T3 (da) 2012-08-20
KR101487304B1 (ko) 2015-01-28
WO2007005604A3 (en) 2008-12-31
BRPI0612411A2 (pt) 2010-11-09
IL188376A (en) 2012-12-31
BRPI0612411A8 (pt) 2017-12-26
US8163980B2 (en) 2012-04-24
CA2613469C (en) 2014-08-12
HK1134495A1 (en) 2010-04-30
EP2489672B1 (en) 2017-01-18

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