ES2385666T3 - SFRP y motivos peptídicos que interactúan con SFRP y sus métodos de uso - Google Patents
SFRP y motivos peptídicos que interactúan con SFRP y sus métodos de uso Download PDFInfo
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- ES2385666T3 ES2385666T3 ES02707454T ES02707454T ES2385666T3 ES 2385666 T3 ES2385666 T3 ES 2385666T3 ES 02707454 T ES02707454 T ES 02707454T ES 02707454 T ES02707454 T ES 02707454T ES 2385666 T3 ES2385666 T3 ES 2385666T3
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- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
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- Organic Chemistry (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US26090801P | 2001-01-10 | 2001-01-10 | |
| US260908P | 2001-01-10 | ||
| PCT/US2002/000869 WO2002055547A2 (en) | 2001-01-10 | 2002-01-10 | Sfrp and peptide motifs that interact with sfrp and methods of their use |
Publications (1)
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| ES2385666T3 true ES2385666T3 (es) | 2012-07-30 |
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| EP (1) | EP1387854B1 (enExample) |
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| EP1731908B1 (en) * | 2004-03-31 | 2010-09-01 | Kazuo Shinya | Method of biosubstance trapping, structural analysis or/and identification with use of a labeling substance |
| KR20070102684A (ko) * | 2004-12-23 | 2007-10-19 | 몰메드 에스피에이 | 접합 생성물 |
| WO2008061029A1 (en) * | 2006-11-10 | 2008-05-22 | Wyeth | Aryl sulfonamide derivatives and methods of their use |
| MX2010010266A (es) * | 2008-03-21 | 2010-12-14 | Adlyfe Inc | Uso de pireno para llevar peptidos a traves de la barrera hematoencefalica. |
| NZ589539A (en) * | 2008-05-16 | 2012-08-31 | Bioexx Specialty Proteins Ltd | Oilseed protein concentrates and isolates, and processes for the production thereof |
| JP2013006783A (ja) * | 2011-06-22 | 2013-01-10 | Nagasaki Univ | 荷重感知遺伝子 |
| FI3116521T3 (fi) * | 2014-03-14 | 2024-10-30 | Univ New York State Res Found | Luun kasvun ja luun rappeutumisen neurogeeninen regulaatio |
| DK3139979T3 (da) | 2014-05-07 | 2023-10-09 | Boehringer Ingelheim Int | Enhed, forstøver og fremgangsmåde |
| US12344886B2 (en) * | 2017-06-15 | 2025-07-01 | Technion Research & Development Foundation Limited | Compositions and methods for detection of genomic variations |
| EP3696192A1 (en) * | 2019-02-15 | 2020-08-19 | Consejo Superior De Investigaciones Científicas | Therapeutic target and monoclonal antibodies against it for the diagnosis and treatment of alzheimer´s disease |
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| US5238839A (en) | 1988-02-09 | 1993-08-24 | Dana Farber Cancer Institute | Nucleic Acids Encoding proteins which induce immunological effector cell activation and chemattraction, vectors, and recombinant cells |
| US5204328A (en) | 1990-06-26 | 1993-04-20 | Merck & Co., Inc. | Peptides having atrial natriuretic factor activity |
| CA2117282A1 (en) | 1991-11-22 | 1993-05-27 | Ofer Lider | Non-peptidic surrogates of the arg-gly-asp sequence and pharmaceutical compositions comprosing them |
| US5578569A (en) | 1993-03-12 | 1996-11-26 | Tam; Cherk S. | Method of increasing bone growth |
| US5536814A (en) | 1993-09-27 | 1996-07-16 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
| US5726156A (en) | 1995-03-06 | 1998-03-10 | Trega Biosciences, Inc. | Cytokine regulatory agents and methods of use in pathologies and conditions associated with altered cytokine levels |
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| US5632983A (en) | 1994-11-17 | 1997-05-27 | University Of South Florida | Method for treating secondary immunodeficiency |
| US5861483A (en) | 1996-04-03 | 1999-01-19 | Pro-Neuron, Inc. | Inhibitor of stem cell proliferation and uses thereof |
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| US5851984A (en) | 1996-08-16 | 1998-12-22 | Genentech, Inc. | Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides |
| PT932678E (pt) | 1996-09-24 | 2006-07-31 | Tanox Inc | Familia de genes que codificam peptidos relacionados com apoptose, peptidos por eles codificados e metodos para sua utilizacao |
| US5939271A (en) | 1997-02-19 | 1999-08-17 | The Regents Of The University Of California | Netrin receptor |
| BR9808545A (pt) | 1997-04-16 | 2000-05-23 | Amgen Inc | ácido nucleico isolado, vetor de expressão, célula hospedeira, processos para produzir uma proteìna de ligação da osteoprotegerina, para detectar a presença de uma proteìna de ligação à osteoprotegerina em uma amostra biológica, para avaliar a capacidade de um composto candidato de ligar-se a uma proteìna de ligação da osteoprotegerina e de um composto de teste para aumentar ou reduzir a ligação da proteìna de ligação da osteoprotegerina a odar, para regular a expressão de uma proteìna de ligação da osteoprotegerina em um animal e para prevenir ou tratar de doença óssea em um mamìfero, polipeptìdeo, protéina de ligação da osteroprotegerina purificada e isolada, ou seu fragmento, análogo ou derivado, e, anticorpo ou seu fragmento |
| US6043053A (en) | 1997-05-23 | 2000-03-28 | Smithkline Beecham Corporation | Wnt-3 polynucleotides |
| AU7704498A (en) | 1997-05-29 | 1998-12-30 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Human frp and fragments thereof including methods for using them |
| EP1012262A4 (en) | 1997-08-12 | 2002-11-06 | Human Genome Sciences Inc | HFLP PROTEIN HFLP |
| WO1999026960A2 (en) | 1997-11-25 | 1999-06-03 | Millennium Pharmaceuticals, Inc. | Genes encoding frizzled-like proteins |
| WO1999029865A2 (en) | 1997-12-12 | 1999-06-17 | The Rockefeller University | A protein belonging to the tnf superfamily, nucleic acids encoding same, and methods of use thereof |
| JPH11196864A (ja) | 1998-01-08 | 1999-07-27 | Deinabekku Kenkyusho:Kk | 破骨細胞の分化を誘導する方法 |
| US6110718A (en) * | 1998-03-20 | 2000-08-29 | Wayne State University | Mammalian putative phosphatidylinositol-4-phosphate-5-kinase |
| WO2001057188A2 (en) | 2000-02-03 | 2001-08-09 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| AU7131200A (en) | 1999-09-13 | 2001-04-17 | Wyeth | Pharmaceutical compositions and methods of using secreted frizzled related protein |
| US6600018B1 (en) * | 2000-04-10 | 2003-07-29 | The United States Of America As Represented By The Department Of Health And Human Services | Secreted frizzled related protein, sFRP, fragments and methods of use thereof |
| JP2002181893A (ja) * | 2000-12-11 | 2002-06-26 | Mitsubishi Electric Corp | 半導体装置の検査方法および検査装置 |
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| US20040077828A1 (en) | 2004-04-22 |
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| PT1387854E (pt) | 2012-06-26 |
| JP2009005704A (ja) | 2009-01-15 |
| JP2007300920A (ja) | 2007-11-22 |
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| DK1387854T3 (da) | 2012-07-09 |
| EP1387854A2 (en) | 2004-02-11 |
| EP1387854B1 (en) | 2012-03-21 |
| US20080145884A1 (en) | 2008-06-19 |
| ATE550345T1 (de) | 2012-04-15 |
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