ES2376493T3 - Procedimiento para reducir o aliviar la inflamación en el tubo digestivo. - Google Patents

Procedimiento para reducir o aliviar la inflamación en el tubo digestivo. Download PDF

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Publication number
ES2376493T3
ES2376493T3 ES07814746T ES07814746T ES2376493T3 ES 2376493 T3 ES2376493 T3 ES 2376493T3 ES 07814746 T ES07814746 T ES 07814746T ES 07814746 T ES07814746 T ES 07814746T ES 2376493 T3 ES2376493 T3 ES 2376493T3
Authority
ES
Spain
Prior art keywords
medicament
disease
ace2
inflammatory
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07814746T
Other languages
English (en)
Spanish (es)
Inventor
Louis Anthony Tartaglia
Thomas Michael Barnes
Robert Mark Coopersmith
Scott Edward Malstrom
David William White
Dominic Picarella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ore Pharmaceuticals Inc
Original Assignee
Ore Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ore Pharmaceuticals Inc filed Critical Ore Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2376493T3 publication Critical patent/ES2376493T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
ES07814746T 2006-09-08 2007-09-07 Procedimiento para reducir o aliviar la inflamación en el tubo digestivo. Active ES2376493T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US82507506P 2006-09-08 2006-09-08
US825075P 2006-09-08
US82780706P 2006-10-02 2006-10-02
US827807P 2006-10-02
PCT/US2007/077857 WO2008031014A1 (en) 2006-09-08 2007-09-07 Method for reducing or alleviating inflammation in the digestive tract

Publications (1)

Publication Number Publication Date
ES2376493T3 true ES2376493T3 (es) 2012-03-14

Family

ID=38670723

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07814746T Active ES2376493T3 (es) 2006-09-08 2007-09-07 Procedimiento para reducir o aliviar la inflamación en el tubo digestivo.

Country Status (11)

Country Link
US (1) US20080234345A1 (enExample)
EP (1) EP2059234B1 (enExample)
JP (1) JP2010502736A (enExample)
CN (1) CN101568331A (enExample)
AT (1) ATE531362T1 (enExample)
AU (1) AU2007292247A1 (enExample)
CA (1) CA2662535A1 (enExample)
DK (1) DK2059234T3 (enExample)
ES (1) ES2376493T3 (enExample)
IL (1) IL197362A0 (enExample)
WO (1) WO2008031014A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2095819A1 (en) * 2008-02-28 2009-09-02 Maastricht University N-benzyl imidazole derivatives and their use as aldosterone synthase inhibitors
JP2011513491A (ja) * 2008-03-10 2011-04-28 オレ・ファーマシューティカルズ・インコーポレーテッド 近位消化管の障害の治療
US20100204286A1 (en) * 2009-02-12 2010-08-12 Donahue Stephen R Method for reducing gastrointestinal adverse effects of cytotoxic agents
JP5845171B2 (ja) * 2010-03-04 2016-01-20 大日本住友製薬株式会社 炎症性腸疾患用薬剤
ES2742195T3 (es) 2010-03-12 2020-02-13 Omeros Corp Inhibidores de PDE10 y composiciones y métodos relacionados
NZ716494A (en) 2014-04-28 2017-07-28 Omeros Corp Processes and intermediates for the preparation of a pde10 inhibitor
NZ716462A (en) 2014-04-28 2017-11-24 Omeros Corp Optically active pde10 inhibitor
MA41271A (fr) * 2014-12-26 2017-10-31 Celgene Alpine Invest Company Ii Llc Méthodes d'utilisation d'oligonucléotides antisens ciblant smad7
AU2016250843A1 (en) 2015-04-24 2017-10-12 Omeros Corporation PDE10 inhibitors and related compositions and methods
WO2017079678A1 (en) 2015-11-04 2017-05-11 Omeros Corporation Solid state forms of a pde10 inhibitor
GB202116266D0 (en) * 2021-11-11 2021-12-29 Bicycletx Ltd Novel use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194556B1 (en) * 1997-12-11 2001-02-27 Millennium Pharmaceuticals, Inc. Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therfor
US7045532B2 (en) 1999-04-30 2006-05-16 Millennium Pharmaceuticals, Inc. ACE-2 modulating compounds and methods of use thereof
IL146000A0 (en) * 1999-04-30 2002-07-25 Millennium Pharm Inc Ace-2 inhibiting compounds and methods of use thereof
US6900033B2 (en) * 2001-06-04 2005-05-31 Human Genome Sciences, Inc. Methods and compositions for modulating ACE-2 activity
GB0203061D0 (en) 2002-02-08 2002-03-27 Novartis Ag Organic compounds
CA2509526A1 (en) * 2002-09-24 2004-04-15 Combinatorx, Incorporated Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
TW200509958A (en) * 2003-02-14 2005-03-16 Combinatorx Inc Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
US20050203168A1 (en) * 2004-03-11 2005-09-15 The Regents Of The University Of Michigan Angiotensin converting enzyme inhibitor use for treatment and prevention of gastrointestinal disorders
WO2008031013A1 (en) * 2006-09-08 2008-03-13 Gene Logic Inc. Method for treating inflammatory diseases of the digestive tract

Also Published As

Publication number Publication date
IL197362A0 (en) 2009-12-24
US20080234345A1 (en) 2008-09-25
WO2008031014A1 (en) 2008-03-13
DK2059234T3 (da) 2011-11-28
EP2059234B1 (en) 2011-11-02
AU2007292247A1 (en) 2008-03-13
EP2059234A1 (en) 2009-05-20
JP2010502736A (ja) 2010-01-28
AU2007292247A2 (en) 2009-03-26
CA2662535A1 (en) 2008-03-13
ATE531362T1 (de) 2011-11-15
CN101568331A (zh) 2009-10-28

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