ES2359467T3 - Compuestos útiles como inhibidores de proteína quinasas. - Google Patents
Compuestos útiles como inhibidores de proteína quinasas. Download PDFInfo
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- ES2359467T3 ES2359467T3 ES07862967T ES07862967T ES2359467T3 ES 2359467 T3 ES2359467 T3 ES 2359467T3 ES 07862967 T ES07862967 T ES 07862967T ES 07862967 T ES07862967 T ES 07862967T ES 2359467 T3 ES2359467 T3 ES 2359467T3
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- aliphatic
- compound
- optionally substituted
- independently
- cycloaliphatic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87487806P | 2006-12-14 | 2006-12-14 | |
| US874878P | 2006-12-14 |
Publications (1)
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|---|---|
| ES2359467T3 true ES2359467T3 (es) | 2011-05-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| ES07862967T Active ES2359467T3 (es) | 2006-12-14 | 2007-12-14 | Compuestos útiles como inhibidores de proteína quinasas. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8129387B2 (enExample) |
| EP (1) | EP2102210B1 (enExample) |
| JP (1) | JP5406725B2 (enExample) |
| CN (1) | CN101646671A (enExample) |
| AT (1) | ATE497961T1 (enExample) |
| AU (1) | AU2007334379B2 (enExample) |
| CA (1) | CA2672612A1 (enExample) |
| DE (1) | DE602007012473D1 (enExample) |
| ES (1) | ES2359467T3 (enExample) |
| MX (1) | MX2009006345A (enExample) |
| NZ (1) | NZ577638A (enExample) |
| WO (1) | WO2008076392A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
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| AR060316A1 (es) | 2006-01-17 | 2008-06-11 | Vertex Pharma | Azaindoles de utilidad como inhibidores de janus quinasas |
| EP2247748A2 (en) * | 2008-02-13 | 2010-11-10 | Elan Pharma International Limited | Alpha-synuclein kinase |
| MX2011000026A (es) | 2008-06-23 | 2011-02-24 | Vertex Pharma | Inhibidores de proteina cinasas. |
| MX2011000021A (es) | 2008-06-23 | 2011-02-24 | Vertex Pharma | Inhibidores de proteina cinasas. |
| US20100075973A1 (en) * | 2008-08-28 | 2010-03-25 | Takeda Pharmaceutical Company Limited | Polo-like kinase inhibitors |
| GEAP202213376A (en) | 2009-06-17 | 2022-02-25 | Vertex Pharmaceuticals Incorporated Us | Inhibitors of influenza viruses replication |
| WO2011079114A1 (en) | 2009-12-23 | 2011-06-30 | Elan Pharmaceuticals, Inc. | Pteridinones as inhibitors of polo - like kinase |
| WO2012048129A2 (en) | 2010-10-08 | 2012-04-12 | Elan Pharmaceuticals, Inc. | Inhibitors of polo-like kinase |
| CN103492381A (zh) | 2010-12-16 | 2014-01-01 | 沃泰克斯药物股份有限公司 | 流感病毒复制的抑制剂 |
| NZ619699A (en) | 2011-07-05 | 2016-03-31 | Vertex Pharma | Processes and intermediates for producing azaindoles |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| WO2014209978A1 (en) * | 2013-06-24 | 2014-12-31 | Merck Patent Gmbh | Imidazole compounds as modulators of fshr and uses thereof |
| LT3068776T (lt) | 2013-11-13 | 2019-08-12 | Vertex Pharmaceuticals Incorporated | Gripo virusų replikacijos inhibitoriai |
| HUE052178T2 (hu) | 2013-11-13 | 2021-04-28 | Vertex Pharma | Eljárások influenzavírus-replikáció inhibitorainak elõállítására |
| WO2016183071A1 (en) | 2015-05-11 | 2016-11-17 | Incyte Corporation | Hetero-tricyclic compounds and their use for the treatment of cancer |
| JP6857617B2 (ja) | 2015-05-13 | 2021-04-14 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | インフルエンザウイルスの複製の阻害剤 |
| WO2016183116A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Methods of preparing inhibitors of influenza viruses replication |
| WO2017027717A1 (en) | 2015-08-12 | 2017-02-16 | Incyte Corporation | Bicyclic fused pyrimidine compounds as tam inhibitors |
| WO2017035366A1 (en) | 2015-08-26 | 2017-03-02 | Incyte Corporation | Pyrrolopyrimidine derivatives as tam inhibitors |
| AU2017241524B2 (en) | 2016-03-28 | 2021-07-08 | Incyte Corporation | Pyrrolotriazine compounds as TAM inhibitors |
| TWI821200B (zh) | 2017-09-27 | 2023-11-11 | 美商英塞特公司 | Tam抑制劑之鹽 |
| US11241438B2 (en) | 2018-06-29 | 2022-02-08 | Incyte Corporation | Formulations of an AXL/MER inhibitor |
| CN111217815B (zh) * | 2018-11-27 | 2021-06-18 | 沈阳药科大学 | 含有喋啶酮骨架的化合物及其制备方法和应用 |
| EP4114401A1 (en) | 2020-03-06 | 2023-01-11 | Incyte Corporation | Combination therapy comprising axl/mer and pd-1/pd-l1 inhibitors |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002505330A (ja) | 1998-03-04 | 2002-02-19 | ブリストル−マイヤーズ スクイブ カンパニー | ヘテロシクロ−置換イミダゾピラジン・たんぱくチロシンキナーゼ抑制剤 |
| UA80743C2 (en) * | 2003-02-26 | 2007-10-25 | Boehringer Ingelheim Pharma | Dihydropteridinones, method for the production and use thereof in the form of drugs |
| US7728134B2 (en) | 2004-08-14 | 2010-06-01 | Boehringer Ingelheim International Gmbh | Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament |
| US20060058311A1 (en) | 2004-08-14 | 2006-03-16 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation |
| US20060074088A1 (en) | 2004-08-14 | 2006-04-06 | Boehringer Ingelheim International Gmbh | Dihydropteridinones for the treatment of cancer diseases |
| NZ577153A (en) | 2006-10-25 | 2012-02-24 | Chroma Therapeutics Ltd | Pteridine derivatives as polo-like kinase inhibitors useful in the treatment of cancer |
| GB0621203D0 (en) | 2006-10-25 | 2006-12-06 | Chroma Therapeutics Ltd | PLK inhibitors |
| JP5580731B2 (ja) | 2007-04-05 | 2014-08-27 | アンドレイ・アレクサンドロビッチ・イワシェンコ | 置換された２，３，４，５−テトラヒドロ−１ｈ−ピリド［４，３−ｂ］インドール、その製造のための方法及び使用 |
| RU2339637C1 (ru) | 2007-04-05 | 2008-11-27 | Андрей Александрович Иващенко | Блокаторы гистаминного рецептора для фармацевтических композиций, обладающих противоаллергическим и аутоиммунным действием |
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2007
- 2007-12-14 CA CA002672612A patent/CA2672612A1/en not_active Abandoned
- 2007-12-14 US US12/448,258 patent/US8129387B2/en not_active Expired - Fee Related
- 2007-12-14 WO PCT/US2007/025688 patent/WO2008076392A2/en not_active Ceased
- 2007-12-14 DE DE602007012473T patent/DE602007012473D1/de active Active
- 2007-12-14 NZ NZ577638A patent/NZ577638A/en not_active IP Right Cessation
- 2007-12-14 JP JP2009541404A patent/JP5406725B2/ja not_active Expired - Fee Related
- 2007-12-14 MX MX2009006345A patent/MX2009006345A/es active IP Right Grant
- 2007-12-14 ES ES07862967T patent/ES2359467T3/es active Active
- 2007-12-14 AT AT07862967T patent/ATE497961T1/de not_active IP Right Cessation
- 2007-12-14 AU AU2007334379A patent/AU2007334379B2/en not_active Ceased
- 2007-12-14 EP EP07862967A patent/EP2102210B1/en not_active Not-in-force
- 2007-12-14 CN CN200780050825A patent/CN101646671A/zh active Pending
-
2012
- 2012-01-24 US US13/356,924 patent/US8557818B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010513285A (ja) | 2010-04-30 |
| JP5406725B2 (ja) | 2014-02-05 |
| EP2102210B1 (en) | 2011-02-09 |
| WO2008076392A2 (en) | 2008-06-26 |
| AU2007334379B2 (en) | 2013-04-18 |
| AU2007334379A1 (en) | 2008-06-26 |
| US20120122879A1 (en) | 2012-05-17 |
| US8129387B2 (en) | 2012-03-06 |
| EP2102210A2 (en) | 2009-09-23 |
| US8557818B2 (en) | 2013-10-15 |
| CA2672612A1 (en) | 2008-06-26 |
| US20100099686A1 (en) | 2010-04-22 |
| WO2008076392A3 (en) | 2008-08-07 |
| CN101646671A (zh) | 2010-02-10 |
| DE602007012473D1 (de) | 2011-03-24 |
| MX2009006345A (es) | 2009-06-23 |
| ATE497961T1 (de) | 2011-02-15 |
| NZ577638A (en) | 2012-03-30 |
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