ES2320550T3 - Parches de principio activo medicinal de aspecto discreto sobre la piel. - Google Patents
Parches de principio activo medicinal de aspecto discreto sobre la piel. Download PDFInfo
- Publication number
- ES2320550T3 ES2320550T3 ES04726478T ES04726478T ES2320550T3 ES 2320550 T3 ES2320550 T3 ES 2320550T3 ES 04726478 T ES04726478 T ES 04726478T ES 04726478 T ES04726478 T ES 04726478T ES 2320550 T3 ES2320550 T3 ES 2320550T3
- Authority
- ES
- Spain
- Prior art keywords
- patch
- skin
- matrix
- active ingredient
- light intensity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000010410 layer Substances 0.000 claims abstract description 53
- 239000004480 active ingredient Substances 0.000 claims abstract description 40
- 239000011159 matrix material Substances 0.000 claims abstract description 30
- 239000000049 pigment Substances 0.000 claims abstract description 28
- 239000000975 dye Substances 0.000 claims abstract description 23
- 239000004615 ingredient Substances 0.000 claims abstract description 15
- 239000000126 substance Substances 0.000 claims abstract description 15
- 238000003860 storage Methods 0.000 claims abstract description 9
- 239000002356 single layer Substances 0.000 claims abstract description 5
- 238000010276 construction Methods 0.000 claims abstract description 3
- 238000004519 manufacturing process Methods 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 12
- 230000003287 optical effect Effects 0.000 claims description 6
- 239000011248 coating agent Substances 0.000 claims description 5
- 238000000576 coating method Methods 0.000 claims description 5
- 238000005259 measurement Methods 0.000 claims description 5
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims description 4
- 230000003667 anti-reflective effect Effects 0.000 claims description 4
- 229960002715 nicotine Drugs 0.000 claims description 4
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims description 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 4
- 230000001225 therapeutic effect Effects 0.000 claims description 3
- 238000004026 adhesive bonding Methods 0.000 claims description 2
- 210000003298 dental enamel Anatomy 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 claims description 2
- 238000000053 physical method Methods 0.000 claims 1
- 235000019646 color tone Nutrition 0.000 description 8
- 239000013543 active substance Substances 0.000 description 7
- 239000003086 colorant Substances 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 229920000139 polyethylene terephthalate Polymers 0.000 description 6
- 239000005020 polyethylene terephthalate Substances 0.000 description 6
- 230000004075 alteration Effects 0.000 description 5
- -1 polydimethylsiloxane, ethylene vinyl acetate copolymers Polymers 0.000 description 5
- 230000000007 visual effect Effects 0.000 description 5
- 239000002537 cosmetic Substances 0.000 description 4
- 230000000873 masking effect Effects 0.000 description 4
- 238000004040 coloring Methods 0.000 description 3
- 238000000354 decomposition reaction Methods 0.000 description 3
- 239000007933 dermal patch Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 229920001400 block copolymer Polymers 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000002483 medication Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000036555 skin type Effects 0.000 description 2
- 229920002554 vinyl polymer Polymers 0.000 description 2
- 238000004383 yellowing Methods 0.000 description 2
- VSKJLJHPAFKHBX-UHFFFAOYSA-N 2-methylbuta-1,3-diene;styrene Chemical compound CC(=C)C=C.C=CC1=CC=CC=C1.C=CC1=CC=CC=C1 VSKJLJHPAFKHBX-UHFFFAOYSA-N 0.000 description 1
- 239000001856 Ethyl cellulose Substances 0.000 description 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
- 238000007123 Ladenburg reaction Methods 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 229920002367 Polyisobutene Polymers 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000003044 adaptive effect Effects 0.000 description 1
- 239000004840 adhesive resin Substances 0.000 description 1
- 229920006223 adhesive resin Polymers 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 239000006117 anti-reflective coating Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- FACXGONDLDSNOE-UHFFFAOYSA-N buta-1,3-diene;styrene Chemical compound C=CC=C.C=CC1=CC=CC=C1.C=CC1=CC=CC=C1 FACXGONDLDSNOE-UHFFFAOYSA-N 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 238000002144 chemical decomposition reaction Methods 0.000 description 1
- 238000004737 colorimetric analysis Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- 235000019325 ethyl cellulose Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000006864 oxidative decomposition reaction Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 238000010422 painting Methods 0.000 description 1
- 230000008447 perception Effects 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920001707 polybutylene terephthalate Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- CHHHXKFHOYLYRE-STWYSWDKSA-M potassium sorbate Chemical compound [K+].C\C=C\C=C\C([O-])=O CHHHXKFHOYLYRE-STWYSWDKSA-M 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 229920000468 styrene butadiene styrene block copolymer Polymers 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Spectrometry And Color Measurement (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10317692 | 2003-04-17 | ||
| DE10317692A DE10317692A1 (de) | 2003-04-17 | 2003-04-17 | Medizinische Wirkstoffpflaster mit veringerter optischer Auffälligkeit auf der Haut |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2320550T3 true ES2320550T3 (es) | 2009-05-25 |
Family
ID=33154271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES04726478T Expired - Lifetime ES2320550T3 (es) | 2003-04-17 | 2004-04-08 | Parches de principio activo medicinal de aspecto discreto sobre la piel. |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US10653636B2 (enExample) |
| EP (1) | EP1615628B1 (enExample) |
| JP (2) | JP5733875B2 (enExample) |
| KR (1) | KR101052127B1 (enExample) |
| CN (1) | CN100450472C (enExample) |
| AT (1) | ATE415954T1 (enExample) |
| AU (1) | AU2004229159B2 (enExample) |
| BR (1) | BRPI0409889B8 (enExample) |
| CA (1) | CA2522962C (enExample) |
| CY (1) | CY1108832T1 (enExample) |
| DE (2) | DE10317692A1 (enExample) |
| DK (1) | DK1615628T3 (enExample) |
| ES (1) | ES2320550T3 (enExample) |
| IL (1) | IL171399A (enExample) |
| MX (1) | MXPA05010935A (enExample) |
| NZ (1) | NZ543195A (enExample) |
| PL (1) | PL1615628T3 (enExample) |
| PT (1) | PT1615628E (enExample) |
| RU (1) | RU2336866C2 (enExample) |
| SI (1) | SI1615628T1 (enExample) |
| WO (1) | WO2004091590A1 (enExample) |
| ZA (1) | ZA200507034B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10317692A1 (de) * | 2003-04-17 | 2004-11-11 | Lts Lohmann Therapie-Systeme Ag | Medizinische Wirkstoffpflaster mit veringerter optischer Auffälligkeit auf der Haut |
| DE102005010255A1 (de) * | 2005-03-07 | 2006-09-14 | Lts Lohmann Therapie-Systeme Ag | Faserfreies transdermales therapeutisches System und Verfahren zu seiner Herstellung |
| RU2367577C1 (ru) | 2005-08-12 | 2009-09-20 | Рик Б. ЙЕГЕР | Система и способ для нанесения изменяющего отражательную способность вещества в целях улучшения визуальной привлекательности человеческой кожи |
| US8942775B2 (en) | 2006-08-14 | 2015-01-27 | Tcms Transparent Beauty Llc | Handheld apparatus and method for the automated application of cosmetics and other substances |
| US8184901B2 (en) | 2007-02-12 | 2012-05-22 | Tcms Transparent Beauty Llc | System and method for applying a reflectance modifying agent to change a person's appearance based on a digital image |
| JP5237112B2 (ja) * | 2006-12-01 | 2013-07-17 | 日東電工株式会社 | 経皮吸収製剤 |
| KR101408454B1 (ko) * | 2006-12-01 | 2014-06-17 | 닛토덴코 가부시키가이샤 | 도네페질 함유 접착 제제의 착색을 억제하는 방법 및 도네페질의 친척 물질의 생성량을 감소시키는 방법 |
| JP2010519185A (ja) | 2007-02-12 | 2010-06-03 | リック ビー． イェーガー， | 作用物質を静電気的に人の皮膚に塗布するためのシステムおよび方法 |
| US10092082B2 (en) | 2007-05-29 | 2018-10-09 | Tcms Transparent Beauty Llc | Apparatus and method for the precision application of cosmetics |
| RU2483729C2 (ru) * | 2008-05-30 | 2013-06-10 | Нитто Денко Корпорейшн | Чрескожно абсорбируемый препарат |
| RU2481826C2 (ru) * | 2008-05-30 | 2013-05-20 | Нитто Денко Корпорейшн | Содержащий донепезил адгезивный препарат и упаковка для него |
| EP3310327A2 (en) * | 2015-06-22 | 2018-04-25 | Johnson & Johnson Consumer Inc. | Method for providing a benefit to skin |
| JP7398750B2 (ja) * | 2019-02-28 | 2023-12-15 | パナソニックＩｐマネジメント株式会社 | 画像処理装置、画像処理方法およびシート |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE7529365U (de) | 1976-01-08 | Beiersdorf Ag, 2000 Hamburg | Wund schnell verband | |
| JPS55111416A (en) * | 1979-02-20 | 1980-08-28 | Taisho Pharmaceut Co Ltd | Paster |
| US4594276A (en) * | 1984-04-09 | 1986-06-10 | Minnesota Mining And Manufacturing Company | Printed, removable body tattoos on a translucent substrate |
| JPH0739566B2 (ja) | 1986-02-21 | 1995-05-01 | 積水化学工業株式会社 | 医療用粘着テープもしくはシートの製造方法 |
| US5004610A (en) * | 1988-06-14 | 1991-04-02 | Alza Corporation | Subsaturated nicotine transdermal therapeutic system |
| US5004510A (en) * | 1989-01-30 | 1991-04-02 | Panzhihua Iron & Steel Co. | Process for manufacturing high strength railroad rails |
| DE4030465C2 (de) * | 1990-09-26 | 1994-06-01 | Ruschke Mona | Pflaster |
| US5120325A (en) * | 1991-06-12 | 1992-06-09 | Fleshtones Products Co., Inc. | Color-matched sterile adhesive bandages containing melanin-like pigment composition |
| CA2075517C (en) * | 1992-04-01 | 1997-03-11 | John Wick | Transdermal patch incorporating a polymer film incorporated with an active agent |
| US5264219A (en) * | 1992-08-07 | 1993-11-23 | Minnesota Mining And Manufacturing Company | Transdermal drug delivery backing |
| JPH07206624A (ja) | 1994-01-20 | 1995-08-08 | Shiseido Co Ltd | 皮膚外用剤 |
| US5536263A (en) * | 1994-03-30 | 1996-07-16 | Lectec Corporation | Non-occulusive adhesive patch for applying medication to the skin |
| DE19519593C1 (de) * | 1995-05-29 | 1996-08-29 | Horstmann Michael | Transdermales Therapeutisches System mit druckfarbenfreier Identifikation und Verfahren zu seiner Herstellung |
| TR199802659T2 (xx) * | 1996-06-20 | 1999-03-22 | Lavipharm S.A. | Topikal akne tedavisi i�in bir ara� ve tedavi y�ntemi. |
| US6025535A (en) * | 1996-10-28 | 2000-02-15 | The Procter & Gamble Company | Topsheet for absorbent articles exhibiting improved masking properties |
| JPH11116470A (ja) * | 1997-08-12 | 1999-04-27 | Takeda Chem Ind Ltd | イデベノン含有経皮投与製剤 |
| HUP0104728A3 (en) * | 1998-12-18 | 2006-07-28 | Alza Corp Mountain View | Transparent transdermal nicotine delivery device |
| DE19912623A1 (de) * | 1999-03-20 | 2000-09-28 | Lohmann Therapie Syst Lts | Verfahren zur Erhöhung der Stabilität bei Lagerung und/oder Anwendung lichtempfindlicher therapeutischer Systeme oder deren Bestandteile |
| AU2000242314B2 (en) * | 2000-04-12 | 2005-11-03 | The Procter & Gamble Company | Pre-formed sheet devices suitable for topical application |
| DE10053375C1 (de) * | 2000-10-27 | 2002-01-24 | Lohmann Therapie Syst Lts | Transdermale therapeutische Systeme mit lichtempfindlichen Wirkstoffen |
| US8586079B2 (en) * | 2002-06-21 | 2013-11-19 | Graphic Productions Inc. | Promotional simulation for transdermal patch sampler |
| DE10317692A1 (de) * | 2003-04-17 | 2004-11-11 | Lts Lohmann Therapie-Systeme Ag | Medizinische Wirkstoffpflaster mit veringerter optischer Auffälligkeit auf der Haut |
-
2003
- 2003-04-17 DE DE10317692A patent/DE10317692A1/de not_active Withdrawn
-
2004
- 2004-04-08 WO PCT/EP2004/003748 patent/WO2004091590A1/de not_active Ceased
- 2004-04-08 NZ NZ543195A patent/NZ543195A/xx not_active IP Right Cessation
- 2004-04-08 KR KR1020057019784A patent/KR101052127B1/ko not_active Expired - Lifetime
- 2004-04-08 DE DE502004008582T patent/DE502004008582D1/de not_active Expired - Lifetime
- 2004-04-08 CA CA2522962A patent/CA2522962C/en not_active Expired - Lifetime
- 2004-04-08 US US10/553,708 patent/US10653636B2/en active Active
- 2004-04-08 CN CNB2004800102813A patent/CN100450472C/zh not_active Expired - Lifetime
- 2004-04-08 AU AU2004229159A patent/AU2004229159B2/en not_active Expired
- 2004-04-08 PL PL04726478T patent/PL1615628T3/pl unknown
- 2004-04-08 AT AT04726478T patent/ATE415954T1/de active
- 2004-04-08 SI SI200431046T patent/SI1615628T1/sl unknown
- 2004-04-08 DK DK04726478T patent/DK1615628T3/da active
- 2004-04-08 MX MXPA05010935A patent/MXPA05010935A/es active IP Right Grant
- 2004-04-08 EP EP04726478A patent/EP1615628B1/de not_active Expired - Lifetime
- 2004-04-08 BR BRPI0409889A patent/BRPI0409889B8/pt not_active IP Right Cessation
- 2004-04-08 PT PT04726478T patent/PT1615628E/pt unknown
- 2004-04-08 ES ES04726478T patent/ES2320550T3/es not_active Expired - Lifetime
- 2004-04-08 JP JP2006505058A patent/JP5733875B2/ja not_active Ceased
- 2004-04-08 RU RU2005129528/15A patent/RU2336866C2/ru active
-
2005
- 2005-09-02 ZA ZA200507034A patent/ZA200507034B/en unknown
- 2005-10-11 IL IL171399A patent/IL171399A/en not_active IP Right Cessation
-
2009
- 2009-02-27 CY CY20091100230T patent/CY1108832T1/el unknown
-
2011
- 2011-12-26 JP JP2011283480A patent/JP2012092133A/ja active Pending
-
2019
- 2019-02-01 US US16/265,427 patent/US10646453B2/en not_active Expired - Lifetime
-
2020
- 2020-03-11 US US16/815,286 patent/US11426358B2/en not_active Expired - Lifetime
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