ES2319776T3 - Terapia de melanoma. - Google Patents

Terapia de melanoma. Download PDF

Info

Publication number
ES2319776T3
ES2319776T3 ES05002951T ES05002951T ES2319776T3 ES 2319776 T3 ES2319776 T3 ES 2319776T3 ES 05002951 T ES05002951 T ES 05002951T ES 05002951 T ES05002951 T ES 05002951T ES 2319776 T3 ES2319776 T3 ES 2319776T3
Authority
ES
Spain
Prior art keywords
melanoma
interferon
interferon alfa
patient
pegylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES05002951T
Other languages
English (en)
Spanish (es)
Inventor
Mary Ellen Rybak
Esther Helen Rose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ES2319776T3 publication Critical patent/ES2319776T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
ES05002951T 1999-04-08 2000-04-06 Terapia de melanoma. Expired - Lifetime ES2319776T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28836699A 1999-04-08 1999-04-08
US288366 1999-04-08

Publications (1)

Publication Number Publication Date
ES2319776T3 true ES2319776T3 (es) 2009-05-12

Family

ID=23106795

Family Applications (2)

Application Number Title Priority Date Filing Date
ES05002951T Expired - Lifetime ES2319776T3 (es) 1999-04-08 2000-04-06 Terapia de melanoma.
ES00107101T Expired - Lifetime ES2239954T3 (es) 1999-04-08 2000-04-06 Terapia contra el melanoma.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES00107101T Expired - Lifetime ES2239954T3 (es) 1999-04-08 2000-04-06 Terapia contra el melanoma.

Country Status (22)

Country Link
EP (3) EP2025344B1 (de)
JP (1) JP2000319195A (de)
CN (1) CN1390132A (de)
AR (1) AR023398A1 (de)
AT (3) ATE496631T1 (de)
AU (1) AU771569B2 (de)
BR (1) BR0009646A (de)
CA (1) CA2303992A1 (de)
CO (1) CO5170404A1 (de)
CY (1) CY1108922T1 (de)
DE (3) DE60020444T2 (de)
DK (2) DK1535622T3 (de)
ES (2) ES2319776T3 (de)
HK (2) HK1032349A1 (de)
HU (1) HU230057B1 (de)
MY (1) MY126763A (de)
NO (1) NO328111B1 (de)
PE (1) PE20010027A1 (de)
PT (2) PT1535622E (de)
TW (1) TWI292320B (de)
WO (1) WO2000061175A2 (de)
ZA (1) ZA200108173B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2710137B1 (de) 2011-03-10 2018-09-19 Provectus Pharmatech, Inc. Eine kombination aus bengalrosa und anti-ctla4 antikörper zur behandlung von krebs

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4530901A (en) 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
US4492537A (en) 1982-12-10 1985-01-08 Awerkamp John B Fluid-operated oil or water well pump
US4917888A (en) 1985-06-26 1990-04-17 Cetus Corporation Solubilization of immunotoxins for pharmaceutical compositions using polymer conjugation
US4766106A (en) 1985-06-26 1988-08-23 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
JP2514950B2 (ja) 1986-03-10 1996-07-10 エフ・ホフマン―ラ ロシユ アーゲー 化学修飾蛋白質,その製造法および中間体
US5595732A (en) 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US5382657A (en) 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
DK0730470T3 (da) 1993-11-10 2002-06-03 Enzon Inc Forbedrede interferonpolymerkonjugater
US5766582A (en) 1994-10-11 1998-06-16 Schering Corporation Stable, aqueous alfa interferon solution formulations
TW426523B (en) 1995-04-06 2001-03-21 Hoffmann La Roche Interferon solution
US5908621A (en) * 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
TW517067B (en) 1996-05-31 2003-01-11 Hoffmann La Roche Interferon conjugates

Also Published As

Publication number Publication date
DE60020444D1 (de) 2005-07-07
DK1535622T3 (da) 2009-04-20
EP2025344B1 (de) 2011-01-26
JP2000319195A (ja) 2000-11-21
ZA200108173B (en) 2003-01-06
WO2000061175A3 (en) 2001-02-01
EP1043026A2 (de) 2000-10-11
ATE496631T1 (de) 2011-02-15
ES2239954T3 (es) 2005-10-16
HK1032349A1 (en) 2001-07-20
CO5170404A1 (es) 2002-06-27
CY1108922T1 (el) 2014-07-02
HUP0200775A2 (en) 2002-08-28
AU771569B2 (en) 2004-03-25
PE20010027A1 (es) 2001-02-05
MY126763A (en) 2006-10-31
AU4204600A (en) 2000-11-14
CN1390132A (zh) 2003-01-08
PT1535622E (pt) 2009-03-19
CA2303992A1 (en) 2000-10-08
DE60020444T2 (de) 2006-05-04
BR0009646A (pt) 2002-02-05
AR023398A1 (es) 2002-09-04
DE60041290D1 (de) 2009-02-12
WO2000061175A2 (en) 2000-10-19
HU230057B1 (hu) 2015-06-29
NO20014852L (no) 2001-12-06
NO328111B1 (no) 2009-12-07
EP1043026A3 (de) 2000-12-20
EP1535622B1 (de) 2008-12-31
PT1043026E (pt) 2005-09-30
DK1043026T3 (da) 2005-07-04
NO20014852D0 (no) 2001-10-05
EP2025344A1 (de) 2009-02-18
DE60045591D1 (de) 2011-03-10
HUP0200775A3 (en) 2002-09-30
HK1075416A1 (en) 2005-12-16
EP1535622A1 (de) 2005-06-01
EP1043026B1 (de) 2005-06-01
ATE296639T1 (de) 2005-06-15
TWI292320B (en) 2008-01-11
ATE419001T1 (de) 2009-01-15

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