ES2313118T3 - Procedimiento para la purificacion de (-)-d9-trans-tetrahidrocannabidol. - Google Patents

Procedimiento para la purificacion de (-)-d9-trans-tetrahidrocannabidol. Download PDF

Info

Publication number
ES2313118T3
ES2313118T3 ES04806191T ES04806191T ES2313118T3 ES 2313118 T3 ES2313118 T3 ES 2313118T3 ES 04806191 T ES04806191 T ES 04806191T ES 04806191 T ES04806191 T ES 04806191T ES 2313118 T3 ES2313118 T3 ES 2313118T3
Authority
ES
Spain
Prior art keywords
phase
stationary
chromatographic
thc
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES04806191T
Other languages
English (en)
Spanish (es)
Inventor
Fiona Obrock Geiser
John James Keenan
Ronald Rossi
Albert Sanchez
John Michael Whelan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson Matthey PLC
Original Assignee
Johnson Matthey PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson Matthey PLC filed Critical Johnson Matthey PLC
Application granted granted Critical
Publication of ES2313118T3 publication Critical patent/ES2313118T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES04806191T 2003-12-23 2004-12-17 Procedimiento para la purificacion de (-)-d9-trans-tetrahidrocannabidol. Expired - Lifetime ES2313118T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0329635 2003-12-23
GBGB0329635.7A GB0329635D0 (en) 2003-12-23 2003-12-23 Process for purifying trans-tetrahydrocannabinol

Publications (1)

Publication Number Publication Date
ES2313118T3 true ES2313118T3 (es) 2009-03-01

Family

ID=30776243

Family Applications (1)

Application Number Title Priority Date Filing Date
ES04806191T Expired - Lifetime ES2313118T3 (es) 2003-12-23 2004-12-17 Procedimiento para la purificacion de (-)-d9-trans-tetrahidrocannabidol.

Country Status (13)

Country Link
US (1) US7449589B2 (https=)
EP (1) EP1697340B1 (https=)
JP (1) JP5566565B2 (https=)
CN (1) CN100482657C (https=)
AT (1) ATE412644T1 (https=)
AU (1) AU2004303593B2 (https=)
CA (1) CA2549399C (https=)
DE (1) DE602004017506D1 (https=)
DK (1) DK1697340T3 (https=)
ES (1) ES2313118T3 (https=)
GB (1) GB0329635D0 (https=)
IL (1) IL176197A (https=)
WO (1) WO2005061480A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI436991B (zh) * 2004-11-22 2014-05-11 歐 賽提克股份有限公司 用於純化反-（-）-△９-四氫大麻酚與反-（＋）-△９-四氫大麻酚之方法
TWI366460B (en) * 2005-06-16 2012-06-21 Euro Celtique Sa Cannabinoid active pharmaceutical ingredient for improved dosage forms
US8980940B2 (en) 2006-11-10 2015-03-17 Johnson Matthey Public Limited Company Stable cannabinoid compositions and methods for making and storing them
US8039509B2 (en) 2006-11-10 2011-10-18 Johnson Matthey Public Limited Company Composition comprising (−)-Δ9-trans-tetrahydrocannabinol
JP6087147B2 (ja) * 2009-06-22 2017-03-01 ジョンソン、マッセイ、パブリック、リミテッド、カンパニーＪｏｈｎｓｏｎ Ｍａｔｔｈｅｙ Ｐｕｂｌｉｃ Ｌｉｍｉｔｅｄ Ｃｏｍｐａｎｙ プロスタグランジンの精製方法
WO2012071389A2 (en) 2010-11-22 2012-05-31 Johnson Matthey Public Limited Company Stable cannabinoid compositions and methods for making and storing them
EP3261629A4 (en) * 2015-02-27 2018-12-05 Ebbu, LLC Compositions comprising combinations of purified cannabinoids, with at least one flavonoid, terpene, or mineral
BR112017018316A2 (pt) 2015-02-27 2018-04-17 Ebbu Llc composições compreendendo combinações de canabinoides purificados, com pelo menos um flavonoide, terpeno ou mineral
DK3455213T3 (da) 2016-05-13 2022-03-07 Symrise Ag Fremgangsmåde til at oprense cannabinoid-forbindelser via simulated moving bed-kromatografi
US12485129B2 (en) 2016-08-29 2025-12-02 Canopy Growth Corporation Water soluble compositions comprising purified cannabinoids
WO2018044953A1 (en) 2016-08-29 2018-03-08 Ebbu, LLC Water soluble compositions comprising purified cannabinoids
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
US11299470B2 (en) 2017-08-07 2022-04-12 Massachusetts Institute Of Technology Systems and methods for separating cannabis-derived compounds using chromatography with liquid or supercritical carbon dioxide
US10307392B2 (en) 2017-10-21 2019-06-04 Alexander Kariman Compound and method for treatment of diseases and disorders
EP3745884A1 (en) 2018-01-31 2020-12-09 Canopy Holdings, Llc Hemp powder
US10751380B2 (en) 2018-03-08 2020-08-25 Alexander Kariman Compound and method for treating spasms, inflammation and pain
US11324718B2 (en) 2018-10-09 2022-05-10 Sartorius Chromatography Equipment Method for purifying cannabinoids
CA3119729A1 (en) 2018-10-10 2020-04-16 Treehouse Biotech, Inc. Synthesis of cannabigerol
CN111848356A (zh) * 2019-04-30 2020-10-30 黑龙江阳光工业大麻研究院 一种大麻二酚的制备方法
EP4337356A1 (en) * 2021-05-13 2024-03-20 Grow Group Plc Method for selective recovery of lipophilic compounds
CN114814009B (zh) * 2022-04-07 2024-06-07 国家烟草质量监督检验中心 一种同时适用于新型烟草产品中酚类化合物及尿液中酚类化合物的代谢物的分析方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403126B1 (en) 1999-05-26 2002-06-11 Websar Innovations Inc. Cannabinoid extraction method
US20030050334A1 (en) 2001-04-30 2003-03-13 Murty Ram B. Process for extraction of Delta-9-Tetrahydrocannabinol and other related cannabinoids and preparation of specific strength marijuana cigarettes
GB0112752D0 (en) 2001-05-25 2001-07-18 Johnson Matthey Plc Synthesis of cannabinoids

Also Published As

Publication number Publication date
WO2005061480A1 (en) 2005-07-07
JP5566565B2 (ja) 2014-08-06
CN1898230A (zh) 2007-01-17
AU2004303593B2 (en) 2010-12-23
IL176197A0 (en) 2006-10-05
ATE412644T1 (de) 2008-11-15
IL176197A (en) 2011-04-28
CA2549399C (en) 2012-12-04
EP1697340B1 (en) 2008-10-29
GB0329635D0 (en) 2004-01-28
DE602004017506D1 (de) 2008-12-11
EP1697340A1 (en) 2006-09-06
CN100482657C (zh) 2009-04-29
DK1697340T3 (da) 2009-03-02
CA2549399A1 (en) 2005-07-07
AU2004303593A1 (en) 2005-07-07
US20070276031A1 (en) 2007-11-29
US7449589B2 (en) 2008-11-11
JP2007516271A (ja) 2007-06-21

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