ES2308040T3 - Comprimido multicapa que contiene parvastatina y aspirina y procedimiento. - Google Patents
Comprimido multicapa que contiene parvastatina y aspirina y procedimiento. Download PDFInfo
- Publication number
- ES2308040T3 ES2308040T3 ES03812825T ES03812825T ES2308040T3 ES 2308040 T3 ES2308040 T3 ES 2308040T3 ES 03812825 T ES03812825 T ES 03812825T ES 03812825 T ES03812825 T ES 03812825T ES 2308040 T3 ES2308040 T3 ES 2308040T3
- Authority
- ES
- Spain
- Prior art keywords
- layer
- aspirin
- tablet
- pravastatin
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 238000000034 method Methods 0.000 title claims abstract description 16
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- TUZYXOIXSAXUGO-PZAWKZKUSA-N pravastatin Chemical compound C1=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@H]2[C@@H](OC(=O)[C@@H](C)CC)C[C@H](O)C=C21 TUZYXOIXSAXUGO-PZAWKZKUSA-N 0.000 claims abstract description 85
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- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
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- Hematology (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US316424 | 1994-09-30 | ||
| US10/316,424 US20040115265A1 (en) | 2002-12-11 | 2002-12-11 | Multilayered tablet containing pravastatin and aspirin and method |
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| ES03812825T Expired - Lifetime ES2308040T3 (es) | 2002-12-11 | 2003-12-03 | Comprimido multicapa que contiene parvastatina y aspirina y procedimiento. |
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| SI (1) | SI1581194T1 (enExample) |
| TW (1) | TWI361700B (enExample) |
| WO (1) | WO2004052289A2 (enExample) |
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| WO2004096201A1 (en) | 2003-04-29 | 2004-11-11 | Orexigen Therapeutics, Inc. | Compositions for affecting weight loss |
| US8163797B2 (en) * | 2003-12-31 | 2012-04-24 | Actavis Elizabeth Llc | Method of treating with stable pravastatin formulation |
| EP1830832A1 (en) * | 2004-12-30 | 2007-09-12 | Genzyme Corporation | Zinc-containing treatments for hyperphosphatemia |
| US20060251722A1 (en) * | 2005-05-03 | 2006-11-09 | Novavax, Inc. | Multi-component vitamin and mineral supplement for the optimal absorption of components |
| WO2007027566A2 (en) * | 2005-09-02 | 2007-03-08 | Genzyme Corporation | Method for removing phosphate and polymer used therefore |
| JP2009514966A (ja) * | 2005-11-08 | 2009-04-09 | ジェンザイム・コーポレーション | 高リン血症のためのマグネシウム含有重合体 |
| ES2761812T3 (es) | 2005-11-22 | 2020-05-21 | Nalpropion Pharmaceuticals Inc | Composición y métodos de aumento de la sensibilidad a la insulina |
| WO2007072060A2 (en) * | 2005-12-23 | 2007-06-28 | Cipla Limited | Particles comprising a core containing a hmg-coa reductase inhibitor and coated with a film |
| EP1970055B1 (en) | 2005-12-29 | 2010-11-24 | Osmotica Kereskedelmi És Szolgáltató Kft | Multi-layered tablet with triple release combination |
| US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
| WO2008005217A2 (en) * | 2006-07-05 | 2008-01-10 | Genzyme Corporation | Iron(ii)-containing treatments for hyperphosphatemia |
| US8765178B2 (en) * | 2006-07-19 | 2014-07-01 | Watson Laboratories, Inc. | Controlled release formulations and associated methods |
| KR20150082689A (ko) | 2006-11-09 | 2015-07-15 | 오렉시젠 세러퓨틱스 인크. | 단위 용량 팩키지 |
| DK2089005T3 (da) * | 2006-11-09 | 2010-07-19 | Orexigen Therapeutics Inc | Lagdelte farmaceutiske formuleringer omfattende et hurtigt opløsende mellemlag |
| WO2008112706A1 (en) | 2007-03-13 | 2008-09-18 | Nutrition 21, Inc. | Methods and compositions for the sustained release of chromium |
| WO2009002867A2 (en) | 2007-06-26 | 2008-12-31 | Nutrition 21, Inc. | Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement |
| KR101330096B1 (ko) * | 2007-10-12 | 2013-11-15 | 페링 인터내셔널 센터 에스 에이 | 구연산, 산화 마그네슘, 중탄산칼륨 및 피코황산나트륨을 포함하는 의약품의 제조 방법, 이러한 방법에 의해 제조된 과립을 포함하는 약제학적 조성물 및 중간체 |
| WO2009158114A1 (en) | 2008-05-30 | 2009-12-30 | Orexigen Therapeutics, Inc. | Methods for treating visceral fat conditions |
| CN102724878A (zh) | 2010-01-11 | 2012-10-10 | 奥雷西根治疗公司 | 在重度抑郁症患者中提供体重减轻疗法的方法 |
| TR201005325A2 (tr) | 2010-06-30 | 2012-01-23 | Bi̇lgi̇ç Mahmut | Atorvastatin ve aspirin içeren farmasötik formülasyonlar |
| KR20120068277A (ko) * | 2010-12-17 | 2012-06-27 | 한미사이언스 주식회사 | ＨＭＧ－ＣｏＡ 환원효소 억제제 및 아스피린을 포함하는 약제학적 복합제제 |
| JP5905031B2 (ja) * | 2011-01-28 | 2016-04-20 | インタッチ テクノロジーズ インコーポレイテッド | モバイルテレプレゼンスロボットとのインタフェーシング |
| HUE072188T2 (hu) | 2012-06-06 | 2025-10-28 | Nalpropion Pharmaceuticals Llc | Készítmény magas kardiovaszkuláris kockázatú túlsúlyos és elhízott páciensek kezelésére szolgáló eljárásban történõ alkalmazásra |
| EP2810644A1 (en) * | 2013-06-06 | 2014-12-10 | Ferrer Internacional, S.A. | Oral formulation for the treatment of cardiovascular diseases |
| GB2564295A (en) | 2016-02-11 | 2019-01-09 | Nutrition 21 Llc | Chromium containing compositions for improving health and fitness |
| JP7109748B2 (ja) * | 2018-12-11 | 2022-08-01 | 日本ジェネリック株式会社 | アジルサルタンとアムロジピンベシル酸塩含有固形製剤及び固形製剤の製造方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4590183A (en) * | 1985-04-22 | 1986-05-20 | Sterling Drug Inc. | Gastric cytoprotection with sodium thiosulfate in oral administration of aspirin |
| JP3172749B2 (ja) * | 1992-02-17 | 2001-06-04 | ライオン株式会社 | イブプロフェン含有製剤 |
| IT1255522B (it) * | 1992-09-24 | 1995-11-09 | Ubaldo Conte | Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita' |
| IT1264517B1 (it) * | 1993-05-31 | 1996-09-24 | Ekita Investments Nv | Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati |
| FR2772615B1 (fr) * | 1997-12-23 | 2002-06-14 | Lipha | Comprime multicouche pour la liberation instantanee puis prolongee de substances actives |
| US6235311B1 (en) * | 1998-03-18 | 2001-05-22 | Bristol-Myers Squibb Company | Pharmaceutical composition containing a combination of a statin and aspirin and method |
| EP1063973B1 (en) * | 1998-03-19 | 2016-11-16 | Bristol-Myers Squibb Company | Biphasic controlled release delivery system for high solubility pharmaceuticals and method |
| US6669955B2 (en) * | 2001-08-28 | 2003-12-30 | Longwood Pharmaceutical Research, Inc. | Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin |
-
2002
- 2002-12-11 US US10/316,424 patent/US20040115265A1/en not_active Abandoned
-
2003
- 2003-12-03 WO PCT/US2003/038774 patent/WO2004052289A2/en not_active Ceased
- 2003-12-03 EP EP03812825A patent/EP1581194B1/en not_active Expired - Lifetime
- 2003-12-03 AT AT03812825T patent/ATE401061T1/de active
- 2003-12-03 PL PL377265A patent/PL206190B1/pl unknown
- 2003-12-03 ES ES03812825T patent/ES2308040T3/es not_active Expired - Lifetime
- 2003-12-03 AU AU2003297689A patent/AU2003297689A1/en not_active Abandoned
- 2003-12-03 PT PT03812825T patent/PT1581194E/pt unknown
- 2003-12-03 DE DE60322264T patent/DE60322264D1/de not_active Expired - Lifetime
- 2003-12-03 DK DK03812825T patent/DK1581194T3/da active
- 2003-12-03 SI SI200331302T patent/SI1581194T1/sl unknown
- 2003-12-03 JP JP2004559355A patent/JP2006511520A/ja active Pending
- 2003-12-08 TW TW092134590A patent/TWI361700B/zh active
- 2003-12-10 MY MYPI20034728A patent/MY140947A/en unknown
-
2005
- 2005-06-07 NO NO20052734A patent/NO338696B1/no not_active IP Right Cessation
- 2005-06-10 IS IS7889A patent/IS2877B/is unknown
-
2008
- 2008-10-14 CY CY20081101137T patent/CY1108414T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1581194B1 (en) | 2008-07-16 |
| TW200505432A (en) | 2005-02-16 |
| CY1108414T1 (el) | 2014-02-12 |
| WO2004052289A3 (en) | 2005-03-24 |
| IS7889A (is) | 2005-06-10 |
| NO20052734D0 (no) | 2005-06-07 |
| DE60322264D1 (de) | 2008-08-28 |
| US20040115265A1 (en) | 2004-06-17 |
| PL377265A1 (pl) | 2006-01-23 |
| NO338696B1 (no) | 2016-10-03 |
| TWI361700B (en) | 2012-04-11 |
| AU2003297689A8 (en) | 2004-06-30 |
| AU2003297689A1 (en) | 2004-06-30 |
| EP1581194A4 (en) | 2006-03-15 |
| ATE401061T1 (de) | 2008-08-15 |
| PL206190B1 (pl) | 2010-07-30 |
| DK1581194T3 (da) | 2008-10-20 |
| EP1581194A2 (en) | 2005-10-05 |
| WO2004052289A2 (en) | 2004-06-24 |
| JP2006511520A (ja) | 2006-04-06 |
| SI1581194T1 (sl) | 2008-12-31 |
| NO20052734L (no) | 2005-07-07 |
| MY140947A (en) | 2010-02-12 |
| PT1581194E (pt) | 2008-09-24 |
| IS2877B (is) | 2014-04-15 |
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