ES2307733T3 - Uso topico de compuestos señuelo nf-kb para tratar la dermatitis atopica. - Google Patents
Uso topico de compuestos señuelo nf-kb para tratar la dermatitis atopica. Download PDFInfo
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- ES2307733T3 ES2307733T3 ES02711351T ES02711351T ES2307733T3 ES 2307733 T3 ES2307733 T3 ES 2307733T3 ES 02711351 T ES02711351 T ES 02711351T ES 02711351 T ES02711351 T ES 02711351T ES 2307733 T3 ES2307733 T3 ES 2307733T3
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- decoy
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- ointment
- kappab
- lure
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/13—Decoys
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Marine Sciences & Fisheries (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001-44350 | 2001-02-20 | ||
| JP2001044350 | 2001-02-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2307733T3 true ES2307733T3 (es) | 2008-12-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| ES02711351T Expired - Lifetime ES2307733T3 (es) | 2001-02-20 | 2002-02-06 | Uso topico de compuestos señuelo nf-kb para tratar la dermatitis atopica. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9012417B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1362600B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP3778357B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE390938T1 (cg-RX-API-DMAC7.html) |
| CY (1) | CY1108165T1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60225899T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1362600T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2307733T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1362600E (cg-RX-API-DMAC7.html) |
| TW (1) | TWI308492B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002066070A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT732929E (pt) * | 1993-10-29 | 2008-08-26 | Brigham & Womens Hospital | Utilização terapêutica de ''engodos'' de elementos cis in vivo |
| TWI308492B (cg-RX-API-DMAC7.html) * | 2001-02-20 | 2009-04-11 | Anges Mg Inc | |
| DE10148886A1 (de) * | 2001-10-04 | 2003-04-30 | Avontec Gmbh | Inhibition von STAT-1 |
| US20070066935A1 (en) * | 2003-05-09 | 2007-03-22 | Ryuichi Morishita | Needleless syringe having medical agent accomodated therein |
| AU2003252493A1 (en) * | 2003-07-09 | 2005-01-28 | Anges Mg, Inc. | Pharmaceutical composition containing decoy and method of using the same |
| US20070293447A1 (en) * | 2003-08-29 | 2007-12-20 | Yasuo Kunugiza | Gene Therapy for Skin Disorders Using Needleless Syringes |
| JP2007512845A (ja) * | 2003-12-02 | 2007-05-24 | アネシバ・インコーポレイテッド | Ｎｆ−κｂオリゴヌクレオチドデコイ分子 |
| US8034619B2 (en) * | 2003-12-19 | 2011-10-11 | University Of Cincinnati | Polyamides for nucleic acid delivery |
| WO2006034433A2 (en) * | 2004-09-21 | 2006-03-30 | Anesiva, Inc. | Delivery of polynucleotides |
| US8067384B2 (en) | 2004-10-22 | 2011-11-29 | Anges Mg, Inc. | Chimera (double) decoy |
| US20090214630A1 (en) * | 2005-05-10 | 2009-08-27 | Warren Strober | Compositions and Methods for the Treatment of Inflammatory Bowel Disease Utilizing NF-KappaB Decoy Polynucleotides |
| US20060258604A1 (en) * | 2005-05-10 | 2006-11-16 | Warren Strober | Compositions and methods for the treatment of inflammatory bowel disease utilizing NF-kappaB decoy polynucleotides |
| EP1892293A4 (en) * | 2005-06-06 | 2008-12-10 | Anges Mg Inc | TRANSCRIPTION FACTOR DECOY |
| US20100035793A1 (en) * | 2005-07-27 | 2010-02-11 | Cheh Peng Lim | Modulators |
| US20100167390A1 (en) * | 2005-12-22 | 2010-07-01 | Toshohiro Nakajima | Novel Oligonucleotide and NF-kB Decoy Comprising the Same |
| WO2007071069A1 (en) * | 2005-12-22 | 2007-06-28 | Institut De Cardiologie De Montreal | Transcription factor decoy oligodeoxynucleotides having multiple cis elements |
| JP4602298B2 (ja) * | 2006-08-31 | 2010-12-22 | ホソカワミクロン株式会社 | 医薬製剤 |
| WO2008099906A1 (ja) | 2007-02-16 | 2008-08-21 | Anges Mg, Inc. | 歯周病、及び外科手術による歯槽骨欠損の治療剤 |
| US20080249044A1 (en) * | 2007-04-03 | 2008-10-09 | Masaya Tanaka | Nucleic acid external skin formulation |
| HRP20150759T1 (hr) | 2007-05-11 | 2015-08-14 | Adynxx, Inc. | Ekspresija gena i bolovi |
| WO2009119836A1 (ja) * | 2008-03-28 | 2009-10-01 | アンジェスＭｇ株式会社 | 転写因子デコイを有効成分とする外用剤組成物 |
| PT2846839T (pt) | 2012-05-10 | 2019-05-29 | Adynxx Inc | Formulações para a administração de ingredientes ativos |
| BR112017002629A2 (pt) | 2014-08-15 | 2018-02-20 | Adynxx, Inc. | decoys de oligonucleotídeo para o tratamento de dor |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2361756A (en) * | 1942-03-31 | 1944-10-31 | George W Fiero | Ointments and the like |
| JPS56135416A (en) * | 1980-03-27 | 1981-10-22 | Mitsubishi Chem Ind Ltd | Pharmaceutical preparation for skin |
| US4301145A (en) * | 1980-07-28 | 1981-11-17 | Cestari Joseph E | Antiseptic skin cream |
| US6150090A (en) | 1986-01-09 | 2000-11-21 | Massachusetts Institute Of Technology | Nuclear factors associated with transcriptional regulation |
| JPH05331066A (ja) * | 1992-05-25 | 1993-12-14 | Toko Yakuhin Kogyo Kk | 尋常性ざ瘡治療用組成物 |
| PT732929E (pt) * | 1993-10-29 | 2008-08-26 | Brigham & Womens Hospital | Utilização terapêutica de ''engodos'' de elementos cis in vivo |
| US6399376B1 (en) * | 1993-11-05 | 2002-06-04 | Isis Pharmaceuticals, Inc. | Modulation of vascular cell adhesive molecule expression through oligonucleotide interactions |
| CA2203566C (en) * | 1994-10-24 | 2001-10-23 | Yuko Hosokawa | Percutaneously administration preparation |
| ES2285712T3 (es) | 1995-05-12 | 2007-11-16 | Anges Mg, Inc. | Medicamento para la terapia y profilaxis de varias enfermedades relacionadas con nf-kappa b. |
| JPH11507245A (ja) * | 1995-11-21 | 1999-06-29 | アイシーエヌ・ファーマシューティカルズ・インコーポレイテッド | Ｉｌ―８およびｉｌ―８受容体に対するアンチセンスオリゴヌクレオチドによる睡瘍増殖の阻害 |
| CA2294988C (en) * | 1997-07-01 | 2015-11-24 | Isis Pharmaceuticals Inc. | Compositions and methods for the delivery of oligonucleotides via the alimentary canal |
| JP2001055331A (ja) * | 1999-06-11 | 2001-02-27 | Toyama Chem Co Ltd | アトピー性皮膚炎治療剤 |
| WO2001057204A1 (en) * | 2000-02-02 | 2001-08-09 | Yasufumi Kaneda | Virus envelope vector for gene transfer |
| DE10049549A1 (de) * | 2000-10-06 | 2002-05-02 | Markus Hecker | Modulation der Transkription pro-inflammatorischer Genprodukte |
| TWI308492B (cg-RX-API-DMAC7.html) | 2001-02-20 | 2009-04-11 | Anges Mg Inc | |
| WO2003063911A1 (en) * | 2002-02-01 | 2003-08-07 | Anges Mg, Inc. | Decoy-containing pharmaceutical compositions and method of using the same |
| JP4971609B2 (ja) | 2004-08-27 | 2012-07-11 | アンジェスＭｇ株式会社 | 核酸皮膚外用製剤 |
| JP2006111591A (ja) | 2004-10-15 | 2006-04-27 | Anges Mg Inc | 核酸医薬を標的特異的に細胞内送達するための製剤 |
-
2002
- 2002-02-06 TW TW091102095A patent/TWI308492B/zh not_active IP Right Cessation
- 2002-02-06 JP JP2002565628A patent/JP3778357B2/ja not_active Expired - Lifetime
- 2002-02-06 PT PT02711351T patent/PT1362600E/pt unknown
- 2002-02-06 EP EP02711351A patent/EP1362600B1/en not_active Expired - Lifetime
- 2002-02-06 DK DK02711351T patent/DK1362600T3/da active
- 2002-02-06 EP EP06004446.8A patent/EP1690544B1/en not_active Expired - Lifetime
- 2002-02-06 ES ES02711351T patent/ES2307733T3/es not_active Expired - Lifetime
- 2002-02-06 US US10/468,717 patent/US9012417B2/en not_active Expired - Fee Related
- 2002-02-06 WO PCT/JP2002/000990 patent/WO2002066070A1/ja not_active Ceased
- 2002-02-06 AT AT02711351T patent/ATE390938T1/de active
- 2002-02-06 DE DE60225899T patent/DE60225899T2/de not_active Expired - Lifetime
-
2008
- 2008-06-30 CY CY20081100682T patent/CY1108165T1/el unknown
- 2008-12-02 US US12/314,009 patent/US20090105183A1/en not_active Abandoned
-
2009
- 2009-02-06 JP JP2009026797A patent/JP4987022B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT1362600E (pt) | 2008-07-09 |
| EP1690544B1 (en) | 2017-09-13 |
| DK1362600T3 (da) | 2008-07-28 |
| TWI308492B (cg-RX-API-DMAC7.html) | 2009-04-11 |
| JP2009102428A (ja) | 2009-05-14 |
| JPWO2002066070A1 (ja) | 2004-06-17 |
| US9012417B2 (en) | 2015-04-21 |
| EP1690544A3 (en) | 2012-03-07 |
| EP1362600A4 (en) | 2005-09-21 |
| EP1690544A2 (en) | 2006-08-16 |
| DE60225899D1 (de) | 2008-05-15 |
| WO2002066070A1 (fr) | 2002-08-29 |
| US20090105183A1 (en) | 2009-04-23 |
| EP1362600A1 (en) | 2003-11-19 |
| ATE390938T1 (de) | 2008-04-15 |
| JP3778357B2 (ja) | 2006-05-24 |
| DE60225899T2 (de) | 2009-04-09 |
| EP1362600B1 (en) | 2008-04-02 |
| US20040162251A1 (en) | 2004-08-19 |
| CY1108165T1 (el) | 2014-02-12 |
| JP4987022B2 (ja) | 2012-07-25 |
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