ES2304462T3 - Metodo de deteccion de cancer de prostata. - Google Patents
Metodo de deteccion de cancer de prostata. Download PDFInfo
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- ES2304462T3 ES2304462T3 ES02789696T ES02789696T ES2304462T3 ES 2304462 T3 ES2304462 T3 ES 2304462T3 ES 02789696 T ES02789696 T ES 02789696T ES 02789696 T ES02789696 T ES 02789696T ES 2304462 T3 ES2304462 T3 ES 2304462T3
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- methylation
- prostate
- gstp1
- subject
- methylated
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- C12Q2523/00—Reactions characterised by treatment of reaction samples
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- C12Q2600/00—Oligonucleotides characterized by their use
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| PCT/US2002/036784 WO2003044232A1 (en) | 2001-11-16 | 2002-11-15 | Method of detection of prostate cancer |
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| US8008012B2 (en) * | 2002-01-24 | 2011-08-30 | Health Discovery Corporation | Biomarkers downregulated in prostate cancer |
| US7718364B2 (en) * | 2003-03-25 | 2010-05-18 | John Wayne Cancer Institute | DNA markers for management of cancer |
| GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
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| EP1689885B1 (en) * | 2003-10-20 | 2012-10-17 | St Vincent's Hospital Sydney Limited | Assessment of predisposition to cancer by quantitative determination of methylation in normal cells of healthy persons. |
| ES2801379T3 (es) | 2003-12-01 | 2021-01-11 | Epigenomics Ag | Métodos y ácidos nucleicos para el análisis de la expresión génica asociada con el desarrollo de trastornos proliferativos de células de próstata |
| JP4537050B2 (ja) * | 2003-12-25 | 2010-09-01 | 国立大学法人三重大学 | 前立腺癌、そのリスク又はその初期罹患の判定方法 |
| WO2005089414A2 (en) * | 2004-03-17 | 2005-09-29 | The Johns Hopkins University | Neoplasia diagnostic compositions and methods of use |
| AU2005230936B2 (en) | 2004-03-26 | 2010-08-05 | Agena Bioscience, Inc. | Base specific cleavage of methylation-specific amplification products in combination with mass analysis |
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| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| US11105808B2 (en) | 2004-11-12 | 2021-08-31 | Health Discovery Corporation | Methods for screening, predicting and monitoring prostate cancer |
| US8268549B2 (en) * | 2005-04-15 | 2012-09-18 | University Of Maryland, Baltimore | Method and assay for determining methylation of GAL3 promoter for early diagnosis of prostate cancer |
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| AU2006339538A1 (en) * | 2005-11-08 | 2007-09-13 | Euclid Diagnostics Llc | Materials and methods for assaying for methylation of CpG islands associated with genes in the evaluation of cancer |
| WO2007081791A2 (en) * | 2006-01-04 | 2007-07-19 | The Johns Hopkins University | Compare-ms:method rapid, sensitive and accurate detection of dna methylation |
| EP1984738A2 (en) | 2006-01-11 | 2008-10-29 | Raindance Technologies, Inc. | Microfluidic devices and methods of use in the formation and control of nanoreactors |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
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| EP2077912B1 (en) | 2006-08-07 | 2019-03-27 | The President and Fellows of Harvard College | Fluorocarbon emulsion stabilizing surfactants |
| IL186935A0 (en) * | 2006-10-31 | 2008-02-09 | Veridex Llc | Prostate cancer field effect analysis methods and kits |
| US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| US20080213781A1 (en) * | 2007-02-15 | 2008-09-04 | Baden Jonathan F | Methods of detecting methylation patterns within a CpG island |
| JP2008202978A (ja) * | 2007-02-16 | 2008-09-04 | Hirosaki Univ | 前立腺癌の診断方法 |
| US20080254455A1 (en) * | 2007-04-12 | 2008-10-16 | Haiying Wang | Detecting prostate cancer |
| WO2008130623A1 (en) | 2007-04-19 | 2008-10-30 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| CN102016067A (zh) * | 2008-01-22 | 2011-04-13 | 维里德克斯有限责任公司 | 前列腺癌中gstp1高甲基化的检测 |
| WO2010009365A1 (en) | 2008-07-18 | 2010-01-21 | Raindance Technologies, Inc. | Droplet libraries |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| US8968210B2 (en) | 2008-10-01 | 2015-03-03 | Covidien LLP | Device for needle biopsy with integrated needle protection |
| US9186128B2 (en) | 2008-10-01 | 2015-11-17 | Covidien Lp | Needle biopsy device |
| US9332973B2 (en) | 2008-10-01 | 2016-05-10 | Covidien Lp | Needle biopsy device with exchangeable needle and integrated needle protection |
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| US9782565B2 (en) | 2008-10-01 | 2017-10-10 | Covidien Lp | Endoscopic ultrasound-guided biliary access system |
| US9279157B2 (en) * | 2009-02-06 | 2016-03-08 | The Regents Of The University Of California | EMX2 in cancer diagnosis and prognosis |
| US8528589B2 (en) | 2009-03-23 | 2013-09-10 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| EP2486409A1 (en) | 2009-10-09 | 2012-08-15 | Universite De Strasbourg | Labelled silica-based nanomaterial with enhanced properties and uses thereof |
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| US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
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| JP2014519310A (ja) | 2011-02-02 | 2014-08-14 | エクザクト サイエンシーズ コーポレイション | Ｄｎａメチル化のデジタル配列分析 |
| WO2012109600A2 (en) | 2011-02-11 | 2012-08-16 | Raindance Technologies, Inc. | Methods for forming mixed droplets |
| US9150852B2 (en) | 2011-02-18 | 2015-10-06 | Raindance Technologies, Inc. | Compositions and methods for molecular labeling |
| EP3709018A1 (en) | 2011-06-02 | 2020-09-16 | Bio-Rad Laboratories, Inc. | Microfluidic apparatus for identifying components of a chemical reaction |
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| US20140274767A1 (en) | 2013-01-23 | 2014-09-18 | The Johns Hopkins University | Dna methylation markers for metastatic prostate cancer |
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| WO2014172288A2 (en) | 2013-04-19 | 2014-10-23 | Raindance Technologies, Inc. | Digital analyte analysis |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| WO2015103367A1 (en) | 2013-12-31 | 2015-07-09 | Raindance Technologies, Inc. | System and method for detection of rna species |
| US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
| US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
| US11427874B1 (en) | 2019-08-26 | 2022-08-30 | Epi One Inc. | Methods and systems for detection of prostate cancer by DNA methylation analysis |
| CN110951871B (zh) * | 2019-11-21 | 2024-01-05 | 瑞博奥(广州)生物科技股份有限公司 | Pca3和psa rna检测试剂盒和扩增体系 |
| CN116179694B (zh) * | 2022-11-02 | 2024-11-05 | 武汉艾米森生命科技有限公司 | 检测甲基化水平的试剂在制备前列腺癌诊断产品中的应用以及前列腺癌诊断试剂盒 |
| CN119391860B (zh) * | 2024-12-25 | 2025-03-21 | 慧算基因科技(上海)有限公司 | 一种用于胰腺癌术后mrd检测及动态监测的引物探针组合物、试剂盒及应用 |
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| US6017704A (en) * | 1996-06-03 | 2000-01-25 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
| AUPP312998A0 (en) * | 1998-04-23 | 1998-05-14 | Commonwealth Scientific And Industrial Research Organisation | Diagnostic assay |
| US6331393B1 (en) * | 1999-05-14 | 2001-12-18 | University Of Southern California | Process for high-throughput DNA methylation analysis |
| JP2004505612A (ja) * | 2000-03-31 | 2004-02-26 | ユニバーシティ・オブ・サザン・カリフォルニア | 食道腺ガンに関する後成的配列 |
| US20050021240A1 (en) * | 2000-11-02 | 2005-01-27 | Epigenomics Ag | Systems, methods and computer program products for guiding selection of a therapeutic treatment regimen based on the methylation status of the DNA |
| DE10112515B4 (de) * | 2001-03-09 | 2004-02-12 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungsmustern mit hoher Sensitivität |
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| EP1456413A4 (en) | 2005-05-18 |
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| US20090181400A1 (en) | 2009-07-16 |
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| ATE393240T1 (de) | 2008-05-15 |
| DE60226271D1 (de) | 2008-06-05 |
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| US20080026395A1 (en) | 2008-01-31 |
| CA2467455A1 (en) | 2003-05-30 |
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| EP1456413B1 (en) | 2008-04-23 |
| US20030124600A1 (en) | 2003-07-03 |
| JP2005509445A (ja) | 2005-04-14 |
| WO2003044232A1 (en) | 2003-05-30 |
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