ES2298785T3 - Proteinas de fusion. - Google Patents

Proteinas de fusion. Download PDF

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Publication number
ES2298785T3
ES2298785T3 ES04753440T ES04753440T ES2298785T3 ES 2298785 T3 ES2298785 T3 ES 2298785T3 ES 04753440 T ES04753440 T ES 04753440T ES 04753440 T ES04753440 T ES 04753440T ES 2298785 T3 ES2298785 T3 ES 2298785T3
Authority
ES
Spain
Prior art keywords
gly
baselineskip
heterologous fusion
fusion proteins
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES04753440T
Other languages
English (en)
Spanish (es)
Inventor
Wolfgang Glaesner
Rohn Lee Millican, Jr.
Yu Tian
Sheng-Hung Rainbow Tschang
Andrew Mark Vick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2298785T3 publication Critical patent/ES2298785T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • C07K14/503Fibroblast growth factor [FGF] basic FGF [bFGF]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES04753440T 2003-06-12 2004-06-10 Proteinas de fusion. Expired - Lifetime ES2298785T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US47788003P 2003-06-12 2003-06-12
US477880P 2003-06-12
US57090804P 2004-05-13 2004-05-13
US570908P 2004-05-13

Publications (1)

Publication Number Publication Date
ES2298785T3 true ES2298785T3 (es) 2008-05-16

Family

ID=33555478

Family Applications (1)

Application Number Title Priority Date Filing Date
ES04753440T Expired - Lifetime ES2298785T3 (es) 2003-06-12 2004-06-10 Proteinas de fusion.

Country Status (17)

Country Link
US (1) US20070253966A1 (enExample)
EP (1) EP1641483B1 (enExample)
JP (1) JP2007505643A (enExample)
CN (1) CN1802167A (enExample)
AT (1) ATE385806T1 (enExample)
AU (1) AU2004247042A1 (enExample)
BR (1) BRPI0411112A (enExample)
CA (1) CA2526169A1 (enExample)
CY (1) CY1107248T1 (enExample)
DE (1) DE602004011770T2 (enExample)
DK (1) DK1641483T3 (enExample)
ES (1) ES2298785T3 (enExample)
MX (1) MXPA05013564A (enExample)
PL (1) PL1641483T3 (enExample)
PT (1) PT1641483E (enExample)
SI (1) SI1641483T1 (enExample)
WO (1) WO2004110472A2 (enExample)

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Also Published As

Publication number Publication date
WO2004110472A2 (en) 2004-12-23
PL1641483T3 (pl) 2008-07-31
MXPA05013564A (es) 2006-03-09
ATE385806T1 (de) 2008-03-15
DE602004011770D1 (de) 2008-03-27
DK1641483T3 (da) 2008-06-02
CY1107248T1 (el) 2012-11-21
CN1802167A (zh) 2006-07-12
BRPI0411112A (pt) 2006-07-18
EP1641483B1 (en) 2008-02-13
US20070253966A1 (en) 2007-11-01
AU2004247042A1 (en) 2004-12-23
WO2004110472A3 (en) 2005-02-03
CA2526169A1 (en) 2004-12-23
DE602004011770T2 (de) 2009-02-05
EP1641483A2 (en) 2006-04-05
PT1641483E (pt) 2008-04-29
SI1641483T1 (sl) 2008-08-31
JP2007505643A (ja) 2007-03-15

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