ES2281658T3 - 3-hidroxi-6-fenilfenantridinas como inhibidores de pde-4. - Google Patents
3-hidroxi-6-fenilfenantridinas como inhibidores de pde-4. Download PDFInfo
- Publication number
- ES2281658T3 ES2281658T3 ES03757767T ES03757767T ES2281658T3 ES 2281658 T3 ES2281658 T3 ES 2281658T3 ES 03757767 T ES03757767 T ES 03757767T ES 03757767 T ES03757767 T ES 03757767T ES 2281658 T3 ES2281658 T3 ES 2281658T3
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- Prior art keywords
- hydrogen
- compounds
- alkoxy
- salts
- alkyl
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| CN108658778A (zh) * | 2018-06-19 | 2018-10-16 | 上海华堇生物技术有限责任公司 | 一种3,4-二甲氧基-β-硝基苯乙烯的新制备方法 |
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| JP4728259B2 (ja) | 2004-02-18 | 2011-07-20 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 効果的なホスホジエステラーゼ（ｐｄｅ）４インヒビターとしての新規のグアニジニル置換されたヒドロキシ−６−フェニルフェナントリジン |
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| RS53543B1 (sr) | 2004-03-03 | 2015-02-27 | Takeda Gmbh | Novi hidroksi-6-heteroarilfenantridini i njihova primena kao pde4 inhibitori |
| EP1745025A2 (en) | 2004-03-09 | 2007-01-24 | Altana Pharma AG | Novel isoamido-substituted hydroxy-6-phenylphenanthridines and their use as pde4 inhibitors |
| JP2007527900A (ja) | 2004-03-10 | 2007-10-04 | アルタナ ファルマ アクチエンゲゼルシャフト | チオ含有の新規のヒドロキシ−６−フェニルフェナントリジン及びｐｄｅ４インヒビターとしてのそれらの使用 |
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| AU2005219581A1 (en) | 2004-03-10 | 2005-09-15 | Nycomed Gmbh | Novel difluoroethoxy-substituted hydroxy-6-phenylphenanthridines and their use as PDE4 inhibitors |
| KR101421914B1 (ko) | 2005-03-02 | 2014-07-22 | 다케다 게엠베하 | 6-헤테로시클릴 치환된 헥사히드로페난트리딘 유도체의 신규한 염 |
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2008
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| WO2004019945A1 (en) | 2004-03-11 |
| DE60311662T2 (de) | 2007-10-25 |
| JP2006508913A (ja) | 2006-03-16 |
| AU2003273805B8 (en) | 2010-06-17 |
| ATE353217T1 (de) | 2007-02-15 |
| JP4587295B2 (ja) | 2010-11-24 |
| DE60311662D1 (en) | 2007-03-22 |
| AU2003273805A1 (en) | 2004-03-19 |
| CA2496459A1 (en) | 2004-03-11 |
| US20050239818A1 (en) | 2005-10-27 |
| AU2003273805B2 (en) | 2009-10-01 |
| EP1536798A1 (en) | 2005-06-08 |
| CA2496459C (en) | 2013-06-25 |
| US7423046B2 (en) | 2008-09-09 |
| US8202880B2 (en) | 2012-06-19 |
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