ES2275729T3 - Compuestos utiles en el tratamiento de enfermedades inflamatorias. - Google Patents
Compuestos utiles en el tratamiento de enfermedades inflamatorias. Download PDFInfo
- Publication number
- ES2275729T3 ES2275729T3 ES01970027T ES01970027T ES2275729T3 ES 2275729 T3 ES2275729 T3 ES 2275729T3 ES 01970027 T ES01970027 T ES 01970027T ES 01970027 T ES01970027 T ES 01970027T ES 2275729 T3 ES2275729 T3 ES 2275729T3
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- Prior art keywords
- reference example
- mixture
- methyl
- morpholin
- give
- Prior art date
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- Expired - Lifetime
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- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/10—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
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Applications Claiming Priority (4)
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| GB0023973A GB0023973D0 (en) | 2000-09-29 | 2000-09-29 | Therapeutically useful compounds |
| GB0023973 | 2000-09-29 | ||
| GB0107643 | 2001-03-27 | ||
| GB0107643A GB0107643D0 (en) | 2001-03-27 | 2001-03-27 | Therapeutically useful compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2275729T3 true ES2275729T3 (es) | 2007-06-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES01970027T Expired - Lifetime ES2275729T3 (es) | 2000-09-29 | 2001-09-28 | Compuestos utiles en el tratamiento de enfermedades inflamatorias. |
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| IL (1) | IL155092A0 (enExample) |
| MX (1) | MXPA03002813A (enExample) |
| NO (1) | NO20031443L (enExample) |
| NZ (1) | NZ525055A (enExample) |
| PL (1) | PL362984A1 (enExample) |
| WO (1) | WO2002026723A1 (enExample) |
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| GB0207450D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| US6750210B2 (en) | 2000-08-05 | 2004-06-15 | Smithkline Beecham Corporation | Formulation containing novel anti-inflammatory androstane derivative |
| US6777399B2 (en) | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
| US6858596B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivative |
| US6787532B2 (en) | 2000-08-05 | 2004-09-07 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivatives |
| GB0019172D0 (en) | 2000-08-05 | 2000-09-27 | Glaxo Group Ltd | Novel compounds |
| US6759398B2 (en) | 2000-08-05 | 2004-07-06 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative |
| US6858593B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
| CA2417826A1 (en) | 2000-08-05 | 2002-02-14 | Glaxo Group Limited | 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents |
| US6777400B2 (en) | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
| UA77656C2 (en) | 2001-04-07 | 2007-01-15 | Glaxo Group Ltd | S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent |
| AR033290A1 (es) | 2001-04-30 | 2003-12-10 | Glaxo Group Ltd | Derivados antiinflamatorios de androstano |
| GB0207449D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| GB0207447D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| TW200400035A (en) | 2002-03-28 | 2004-01-01 | Glaxo Group Ltd | Novel compounds |
| GB0207439D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| GB0207432D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| GB0207436D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| GB0211759D0 (en) * | 2002-05-22 | 2002-07-03 | Glaxo Group Ltd | Novel compounds |
| GB0212357D0 (en) * | 2002-05-29 | 2002-07-10 | Glaxo Group Ltd | Novel compounds |
| GB2389530B (en) | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
| AU2003275257A1 (en) | 2002-09-26 | 2004-04-19 | Bristol-Myers Squibb Company | N-substituted heterocyclic amines as modulators of chemokine receptor activity |
| ATE446951T1 (de) * | 2003-06-10 | 2009-11-15 | Biondi Ricardo Miguel | Verwendung einer verbingung gemäss formel i zur herstellung einer pharmazeutischen zubereitung |
| RU2387646C2 (ru) | 2003-08-29 | 2010-04-27 | Рэнбакси Лабораториз Лимитед | Ингибиторы фосфодиэстеразы типа-iv |
| CA2579207C (en) | 2004-09-08 | 2011-10-18 | Mitsubishi Pharma Corporation | Morpholine compound |
| EP1992628A1 (en) | 2007-05-18 | 2008-11-19 | Glaxo Group Limited | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones |
| EP1958947A1 (en) | 2007-02-15 | 2008-08-20 | Ranbaxy Laboratories Limited | Inhibitors of phosphodiesterase type 4 |
| JP2010521456A (ja) * | 2007-03-13 | 2010-06-24 | アレテ セラピューティクス， インコーポレイテッド | 可溶性エポキシドヒドロラーゼ阻害剤 |
| JP5313881B2 (ja) | 2007-04-04 | 2013-10-09 | 興和株式会社 | テトラヒドロイソキノリン化合物 |
| US8093248B2 (en) | 2007-12-05 | 2012-01-10 | Astrazeneca Ab (Publ) | Compounds useful for the treatment of conditions associated with weight gain |
| WO2009071658A1 (en) | 2007-12-05 | 2009-06-11 | Biovitrum Ab (Publ) | Piperazines as anti-obesity agents |
| US20140335083A1 (en) | 2011-12-01 | 2014-11-13 | Glaxo Group Limited | Methods of treatment and prevention of eye diseases |
| FR3022142B1 (fr) | 2014-06-16 | 2019-07-12 | Universite Paul Sabatier - Toulouse Iii | Inhibition de la chimiokine ccl7 ou de son recepteur ccr3 pour le traitement et le diagnostic du cancer de la prostate |
| AR101674A1 (es) | 2014-08-22 | 2017-01-04 | Glaxosmithkline Ip Dev Ltd | Uso de un compuesto tricíclico que contiene nitrógeno |
| WO2018134731A1 (en) | 2017-01-17 | 2018-07-26 | Glaxosmithkline Intellectual Property Development Limited | Non peptidic heterobivalent molecules for treating inflammatory diseases |
| TW202140550A (zh) | 2020-01-29 | 2021-11-01 | 瑞士商諾華公司 | 使用抗ｔｓｌｐ抗體治療炎性或阻塞性氣道疾病之方法 |
| CN111269340B (zh) * | 2020-03-31 | 2020-12-29 | 台州学院 | 一种以1-甲烷磺酰哌嗪为配体的螯合树脂及其制备方法和应用 |
| CN120132049B (zh) * | 2025-03-05 | 2025-08-26 | 西南医科大学附属口腔医院 | 茶多酚涂层改性的3d打印掺锶羟基磷灰石复合支架的制备方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP3087763B2 (ja) | 1990-11-30 | 2000-09-11 | 三井化学株式会社 | 新規な複素環式化合物およびそれを含有する医薬組成物 |
| JPH04247074A (ja) * | 1991-02-01 | 1992-09-03 | Yoshitomi Pharmaceut Ind Ltd | ４−モルホリノ安息香酸誘導体の製造法 |
| JPH04270272A (ja) * | 1991-02-25 | 1992-09-25 | Yoshitomi Pharmaceut Ind Ltd | アミノアルキルモルホリン誘導体の製造法 |
| WO1995031431A1 (en) | 1994-05-18 | 1995-11-23 | Nisshin Flour Milling Co., Ltd. | Novel diaminomethylidene derivative |
| US5753654A (en) * | 1994-05-18 | 1998-05-19 | Nisshin Flour Milling Co., Ltd. | Diaminomethylidene derivatives |
| HU227841B1 (en) * | 1997-11-12 | 2012-05-02 | Bayer Pharma AG | 2-phenyl substituted imidazotriazinones, process for their preparation and pharmaceutical compositions thereof |
| BR9915520A (pt) * | 1998-11-20 | 2001-07-17 | Hoffmann La Roche | Antagonistas receptores ccr-3 derivados de pirrolidina |
| AU2482100A (en) * | 1998-12-18 | 2000-07-03 | Du Pont Pharmaceuticals Company | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
| EP1140833A1 (en) * | 1998-12-18 | 2001-10-10 | Du Pont Pharmaceuticals Company | 2-substituted-4-nitrogen heterocycles as modulators of chemokine receptor activity |
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- 2001-09-28 CA CA002423305A patent/CA2423305A1/en not_active Abandoned
- 2001-09-28 KR KR10-2003-7004593A patent/KR20030040510A/ko not_active Withdrawn
- 2001-09-28 CN CNA018196489A patent/CN1478084A/zh active Pending
- 2001-09-28 HU HU0303107A patent/HUP0303107A2/hu unknown
- 2001-09-28 EP EP01970027A patent/EP1324991B1/en not_active Expired - Lifetime
- 2001-09-28 JP JP2002531107A patent/JP5069392B2/ja not_active Expired - Lifetime
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- 2001-09-28 CZ CZ20031194A patent/CZ20031194A3/cs unknown
- 2001-09-28 US US10/381,871 patent/US7157457B2/en not_active Expired - Lifetime
- 2001-09-28 WO PCT/GB2001/004350 patent/WO2002026723A1/en not_active Ceased
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- 2001-09-28 AR ARP010104603A patent/AR037080A1/es not_active Application Discontinuation
- 2001-09-28 MX MXPA03002813A patent/MXPA03002813A/es unknown
- 2001-09-28 EP EP05076503A patent/EP1586567A1/en not_active Withdrawn
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2003
- 2003-03-28 NO NO20031443A patent/NO20031443L/no unknown
Also Published As
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| AU2001290146A1 (en) | 2002-04-08 |
| NZ525055A (en) | 2004-09-24 |
| CZ20031194A3 (cs) | 2003-08-13 |
| KR20030040510A (ko) | 2003-05-22 |
| ATE345331T1 (de) | 2006-12-15 |
| AR037080A1 (es) | 2004-10-20 |
| DE60124576T2 (de) | 2007-06-21 |
| WO2002026723A1 (en) | 2002-04-04 |
| DE60124576D1 (de) | 2006-12-28 |
| JP5069392B2 (ja) | 2012-11-07 |
| US20040058907A1 (en) | 2004-03-25 |
| NO20031443D0 (no) | 2003-03-28 |
| CA2423305A1 (en) | 2002-04-04 |
| CN1478084A (zh) | 2004-02-25 |
| NO20031443L (no) | 2003-05-26 |
| US7157457B2 (en) | 2007-01-02 |
| BR0114321A (pt) | 2003-07-01 |
| EP1324991B1 (en) | 2006-11-15 |
| MXPA03002813A (es) | 2003-10-15 |
| EP1586567A1 (en) | 2005-10-19 |
| IL155092A0 (en) | 2003-10-31 |
| PL362984A1 (en) | 2004-11-15 |
| JP2004509953A (ja) | 2004-04-02 |
| EP1324991A1 (en) | 2003-07-09 |
| HUP0303107A2 (hu) | 2004-03-01 |
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