ES2262893T3 - Derivados de imidazo-piridina para su uso en el tratamiento de infeccion virica por herpes. - Google Patents

Derivados de imidazo-piridina para su uso en el tratamiento de infeccion virica por herpes.

Info

Publication number
ES2262893T3
ES2262893T3 ES02800844T ES02800844T ES2262893T3 ES 2262893 T3 ES2262893 T3 ES 2262893T3 ES 02800844 T ES02800844 T ES 02800844T ES 02800844 T ES02800844 T ES 02800844T ES 2262893 T3 ES2262893 T3 ES 2262893T3
Authority
ES
Spain
Prior art keywords
formula
compound
group
het
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02800844T
Other languages
English (en)
Spanish (es)
Inventor
Kristjan GlaxoSmithKline GUDMUNDSSON
Brian A. GlaxoSmithKline JOHNS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of ES2262893T3 publication Critical patent/ES2262893T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES02800844T 2001-10-05 2002-09-23 Derivados de imidazo-piridina para su uso en el tratamiento de infeccion virica por herpes. Expired - Lifetime ES2262893T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32770501P 2001-10-05 2001-10-05
US327705P 2001-10-05

Publications (1)

Publication Number Publication Date
ES2262893T3 true ES2262893T3 (es) 2006-12-01

Family

ID=23277681

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02800844T Expired - Lifetime ES2262893T3 (es) 2001-10-05 2002-09-23 Derivados de imidazo-piridina para su uso en el tratamiento de infeccion virica por herpes.

Country Status (7)

Country Link
US (2) US7244740B2 (OSRAM)
EP (1) EP1432712B1 (OSRAM)
JP (1) JP2005508955A (OSRAM)
AT (1) ATE326466T1 (OSRAM)
DE (1) DE60211539T2 (OSRAM)
ES (1) ES2262893T3 (OSRAM)
WO (1) WO2003031446A1 (OSRAM)

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US7442697B2 (en) 2002-03-09 2008-10-28 Astrazeneca Ab 4-imidazolyl substituted pyrimidine derivatives with CDK inhibitory activity
JP2006520819A (ja) * 2003-03-06 2006-09-14 メルク　エンド　カムパニー　インコーポレーテッド 抗原虫薬イミダゾピリジン化合物
GB0311274D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
GB0311276D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
TW200528101A (en) 2004-02-03 2005-09-01 Astrazeneca Ab Chemical compounds
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UA103319C2 (en) 2008-05-06 2013-10-10 Глаксосмитклайн Ллк Thiazole- and oxazole-benzene sulfonamide compounds
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CA2729965A1 (en) 2008-07-14 2010-01-21 Gilead Sciences, Inc. Fused heterocyclyc inhibitor compounds
JP5640005B2 (ja) 2008-07-14 2014-12-10 ギリアード サイエンシーズ， インコーポレイテッド Ｈｄａｃおよび／またはｃｄｋ阻害剤としてのイミダゾシルピリジン化合物
KR20110038159A (ko) 2008-07-28 2011-04-13 길리애드 사이언시즈, 인코포레이티드 사이클로알킬리덴 및 헤테로사이클로알킬리덴 히스톤 데아세틸라아제 억제제 화합물
AU2010259035A1 (en) 2009-06-08 2011-12-08 Gilead Sciences, Inc. Alkanoylamino benzamide aniline HDAC inhibitor compounds
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NZ599597A (en) 2009-10-30 2013-05-31 Janssen Pharmaceutica Nv IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVES AND THEIR USE AS PDE10 INHIBITORS
AR080754A1 (es) 2010-03-09 2012-05-09 Janssen Pharmaceutica Nv Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10
ES2575092T3 (es) 2011-06-27 2016-06-24 Janssen Pharmaceutica, N.V. Derivados de 1-aril-4-metil-[1,2,4]triazolo[4,3-a]quinoxalina
RU2657540C2 (ru) 2012-06-26 2018-06-14 Янссен Фармацевтика Нв Комбинации, содержащие ингибиторы pde 2, такие как 1-арил-4-метил-[1,2,4]триазоло[4,3-а]хиноксалиновые соединения, и ингибиторы pde 10, для применения в лечении неврологических или метаболических расстройств
KR102171706B1 (ko) 2012-07-09 2020-10-30 얀센 파마슈티카 엔.브이. 포스포디에스테라아제 10 효소의 억제제
US11111245B2 (en) 2017-02-01 2021-09-07 Aucentra Therapeutics Pty Ltd Derivatives of N-cycloalkyl/heterocycloalkyl-4-(imidazo[1,2-a]pyridine)pyrimidin-2-amine as therapeutic agents
CN120829428A (zh) * 2024-04-18 2025-10-24 中国医学科学院药物研究所 咪唑并吡啶衍生物及其用途

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Also Published As

Publication number Publication date
US7244740B2 (en) 2007-07-17
US20080139594A1 (en) 2008-06-12
JP2005508955A (ja) 2005-04-07
US20040248917A1 (en) 2004-12-09
DE60211539D1 (de) 2006-06-22
EP1432712B1 (en) 2006-05-17
DE60211539T2 (de) 2006-09-21
ATE326466T1 (de) 2006-06-15
WO2003031446A1 (en) 2003-04-17
EP1432712A1 (en) 2004-06-30

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