ES2254980T3 - Derivados de acido endiandrico h como inhibidores de c-maf para uso contra el asma. - Google Patents

Derivados de acido endiandrico h como inhibidores de c-maf para uso contra el asma.

Info

Publication number
ES2254980T3
ES2254980T3 ES03784025T ES03784025T ES2254980T3 ES 2254980 T3 ES2254980 T3 ES 2254980T3 ES 03784025 T ES03784025 T ES 03784025T ES 03784025 T ES03784025 T ES 03784025T ES 2254980 T3 ES2254980 T3 ES 2254980T3
Authority
ES
Spain
Prior art keywords
compound
formula
alkenyl
alkyl
branched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES03784025T
Other languages
English (en)
Spanish (es)
Inventor
Claudia Eder
Herbert Kogler
Sabine Haag-Richter
Robert Walker Singleton
Arun Subramaniam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Sanofi Aventis Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Application granted granted Critical
Publication of ES2254980T3 publication Critical patent/ES2254980T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ES03784025T 2002-08-02 2003-07-18 Derivados de acido endiandrico h como inhibidores de c-maf para uso contra el asma. Expired - Lifetime ES2254980T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10235624A DE10235624A1 (de) 2002-08-02 2002-08-02 Endiandric acid H und ihre Derivate, Verfahren zu ihrer Herstellung und Verwendung derselben
DE10235624 2002-08-02

Publications (1)

Publication Number Publication Date
ES2254980T3 true ES2254980T3 (es) 2006-06-16

Family

ID=30469404

Family Applications (1)

Application Number Title Priority Date Filing Date
ES03784025T Expired - Lifetime ES2254980T3 (es) 2002-08-02 2003-07-18 Derivados de acido endiandrico h como inhibidores de c-maf para uso contra el asma.

Country Status (13)

Country Link
US (1) US7019028B2 (https=)
EP (1) EP1529040B1 (https=)
JP (1) JP4598523B2 (https=)
AT (1) ATE314359T1 (https=)
AU (1) AU2003250099B2 (https=)
BR (1) BR0313199A (https=)
CA (1) CA2493483C (https=)
DE (2) DE10235624A1 (https=)
DK (1) DK1529040T3 (https=)
ES (1) ES2254980T3 (https=)
IL (1) IL166439A (https=)
MX (1) MXPA05000387A (https=)
WO (1) WO2004014888A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1944361A1 (en) 2007-01-11 2008-07-16 INSERM (Institut National de la Santé et de la Recherche Médicale) A method for expanding monocytes
CN108192972B (zh) 2010-10-06 2022-09-09 生物医学研究机构基金会 用于乳腺癌转移的诊断、预后和治疗的方法
EP2650682A1 (en) 2012-04-09 2013-10-16 Fundació Privada Institut de Recerca Biomèdica Method for the prognosis and treatment of cancer metastasis
BR112014030750A2 (pt) 2012-06-06 2017-08-22 Inst Catalana Recerca Estudis Avancats Método para diagnóstico, prognóstico e tratamento da metástase do câncer pulmonar
US10119171B2 (en) 2012-10-12 2018-11-06 Inbiomotion S.L. Method for the diagnosis, prognosis and treatment of prostate cancer metastasis
ES2906586T3 (es) 2012-10-12 2022-04-19 Inbiomotion Sl Método para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de próstata
WO2015019125A1 (en) * 2013-08-05 2015-02-12 Societe De Developpement Et De Recherche Industrielle Molecular targets for the treatment of wounds, in particular chronic wounds
US11596642B2 (en) 2016-05-25 2023-03-07 Inbiomotion S.L. Therapeutic treatment of breast cancer based on c-MAF status
KR20200104298A (ko) 2017-11-22 2020-09-03 인바이오모션 에스.엘. c-MAF 상태에 기반한 유방암의 요법 치료

Also Published As

Publication number Publication date
BR0313199A (pt) 2005-06-21
IL166439A (en) 2009-12-24
MXPA05000387A (es) 2005-03-23
IL166439A0 (en) 2006-01-15
US7019028B2 (en) 2006-03-28
DE50302084D1 (de) 2006-02-02
EP1529040B1 (de) 2005-12-28
AU2003250099B2 (en) 2008-12-18
DE10235624A1 (de) 2004-02-19
JP2006503006A (ja) 2006-01-26
ATE314359T1 (de) 2006-01-15
DK1529040T3 (da) 2006-05-08
CA2493483A1 (en) 2004-02-19
US20040138313A1 (en) 2004-07-15
AU2003250099A1 (en) 2004-02-25
CA2493483C (en) 2011-09-20
JP4598523B2 (ja) 2010-12-15
EP1529040A1 (de) 2005-05-11
WO2004014888A1 (de) 2004-02-19

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