ATE314359T1 - Endiandric acid h derivate als c-maf inhibitoren zur verwendung gegen asthma - Google Patents
Endiandric acid h derivate als c-maf inhibitoren zur verwendung gegen asthmaInfo
- Publication number
- ATE314359T1 ATE314359T1 AT03784025T AT03784025T ATE314359T1 AT E314359 T1 ATE314359 T1 AT E314359T1 AT 03784025 T AT03784025 T AT 03784025T AT 03784025 T AT03784025 T AT 03784025T AT E314359 T1 ATE314359 T1 AT E314359T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- optionally substituted
- use against
- against asthma
- alkenyloxy
- Prior art date
Links
- 208000006673 asthma Diseases 0.000 title 1
- XYHDKVJBIKILGM-UHFFFAOYSA-N endiandric acid H Natural products C1=C2OCOC2=CC(C2=CC(C3CC4C(CC(O)=O)C5C=CC2C3C54)O)=C1 XYHDKVJBIKILGM-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000006323 alkenyl amino group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000005133 alkynyloxy group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- AOJDZKCUAATBGE-UHFFFAOYSA-N bromomethane Chemical compound Br[CH2] AOJDZKCUAATBGE-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Medicines Containing Plant Substances (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10235624A DE10235624A1 (de) | 2002-08-02 | 2002-08-02 | Endiandric acid H und ihre Derivate, Verfahren zu ihrer Herstellung und Verwendung derselben |
| PCT/EP2003/007821 WO2004014888A1 (de) | 2002-08-02 | 2003-07-18 | Endiandric acid h derivate als c-maf inhibitoren zur verwendung gegen asthma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE314359T1 true ATE314359T1 (de) | 2006-01-15 |
Family
ID=30469404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03784025T ATE314359T1 (de) | 2002-08-02 | 2003-07-18 | Endiandric acid h derivate als c-maf inhibitoren zur verwendung gegen asthma |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7019028B2 (https=) |
| EP (1) | EP1529040B1 (https=) |
| JP (1) | JP4598523B2 (https=) |
| AT (1) | ATE314359T1 (https=) |
| AU (1) | AU2003250099B2 (https=) |
| BR (1) | BR0313199A (https=) |
| CA (1) | CA2493483C (https=) |
| DE (2) | DE10235624A1 (https=) |
| DK (1) | DK1529040T3 (https=) |
| ES (1) | ES2254980T3 (https=) |
| IL (1) | IL166439A (https=) |
| MX (1) | MXPA05000387A (https=) |
| WO (1) | WO2004014888A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1944361A1 (en) | 2007-01-11 | 2008-07-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A method for expanding monocytes |
| CN108192972B (zh) | 2010-10-06 | 2022-09-09 | 生物医学研究机构基金会 | 用于乳腺癌转移的诊断、预后和治疗的方法 |
| EP2650682A1 (en) | 2012-04-09 | 2013-10-16 | Fundació Privada Institut de Recerca Biomèdica | Method for the prognosis and treatment of cancer metastasis |
| BR112014030750A2 (pt) | 2012-06-06 | 2017-08-22 | Inst Catalana Recerca Estudis Avancats | Método para diagnóstico, prognóstico e tratamento da metástase do câncer pulmonar |
| US10119171B2 (en) | 2012-10-12 | 2018-11-06 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
| ES2906586T3 (es) | 2012-10-12 | 2022-04-19 | Inbiomotion Sl | Método para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de próstata |
| WO2015019125A1 (en) * | 2013-08-05 | 2015-02-12 | Societe De Developpement Et De Recherche Industrielle | Molecular targets for the treatment of wounds, in particular chronic wounds |
| US11596642B2 (en) | 2016-05-25 | 2023-03-07 | Inbiomotion S.L. | Therapeutic treatment of breast cancer based on c-MAF status |
| KR20200104298A (ko) | 2017-11-22 | 2020-09-03 | 인바이오모션 에스.엘. | c-MAF 상태에 기반한 유방암의 요법 치료 |
-
2002
- 2002-08-02 DE DE10235624A patent/DE10235624A1/de not_active Withdrawn
-
2003
- 2003-07-18 MX MXPA05000387A patent/MXPA05000387A/es active IP Right Grant
- 2003-07-18 EP EP03784025A patent/EP1529040B1/de not_active Expired - Lifetime
- 2003-07-18 DE DE50302084T patent/DE50302084D1/de not_active Expired - Lifetime
- 2003-07-18 WO PCT/EP2003/007821 patent/WO2004014888A1/de not_active Ceased
- 2003-07-18 ES ES03784025T patent/ES2254980T3/es not_active Expired - Lifetime
- 2003-07-18 AT AT03784025T patent/ATE314359T1/de active
- 2003-07-18 AU AU2003250099A patent/AU2003250099B2/en not_active Ceased
- 2003-07-18 CA CA2493483A patent/CA2493483C/en not_active Expired - Fee Related
- 2003-07-18 DK DK03784025T patent/DK1529040T3/da active
- 2003-07-18 JP JP2004526742A patent/JP4598523B2/ja not_active Expired - Fee Related
- 2003-07-18 BR BR0313199-8A patent/BR0313199A/pt not_active Application Discontinuation
- 2003-07-25 US US10/627,850 patent/US7019028B2/en not_active Expired - Fee Related
-
2005
- 2005-01-23 IL IL166439A patent/IL166439A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BR0313199A (pt) | 2005-06-21 |
| IL166439A (en) | 2009-12-24 |
| MXPA05000387A (es) | 2005-03-23 |
| IL166439A0 (en) | 2006-01-15 |
| US7019028B2 (en) | 2006-03-28 |
| DE50302084D1 (de) | 2006-02-02 |
| EP1529040B1 (de) | 2005-12-28 |
| AU2003250099B2 (en) | 2008-12-18 |
| DE10235624A1 (de) | 2004-02-19 |
| JP2006503006A (ja) | 2006-01-26 |
| ES2254980T3 (es) | 2006-06-16 |
| DK1529040T3 (da) | 2006-05-08 |
| CA2493483A1 (en) | 2004-02-19 |
| US20040138313A1 (en) | 2004-07-15 |
| AU2003250099A1 (en) | 2004-02-25 |
| CA2493483C (en) | 2011-09-20 |
| JP4598523B2 (ja) | 2010-12-15 |
| EP1529040A1 (de) | 2005-05-11 |
| WO2004014888A1 (de) | 2004-02-19 |
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